Anda di halaman 1dari 52

1.

2.
3.
4.
5.
6.
7.
8.
9.

1.
2.
3.
4.
5.
6.





2554

1.1
1.2
1.3
1.4
1.5

1.6
1.7

7
8
8
9

9
11
11

15

2.1
2.2
2.3
2.4

15
16
16
16

19

3.1
3.2
3.3


3.4

19
26
27
27
37
38




3.3.1
3.3.2

41

43

49

53

1.1

1.1.1
1.1.2

1.2

(Ambient environmental Quality Standard)

(Effluent Standard)

(Descriptive)

(Performance Based)

(Effluent Standard)




1.3


1.3.1

( 3.00 ) (U.S. EPA. 2001)



1.3.2



()

1.4

()

1.5




1.5.1

20 (.. 2543) -

.. 2535

25 (.. 2547)



1.5.2

1.5.2.1




Soil Screening Guidance

U.S. Environmental Protection Agency U.S. EPA.

National Priorities List (NPL)

(Conservative)

1.5.2.2

1)


2)

1.1 1.4

1.5.2.3

3

( < 1.0) ( < 104 106)

10

1.6

1)
2)
3)



1.6.1



1.6.2 ()

1.6.3

1.6.4 (Default)

1.6.5 2

( < 1.0) ( < 106)

1.7




1.7.1

(Concept)

11

2 3

( 1.1)



1.1 (Concept)

12


1.7.2 1.7.1

(Default)



1.7.3

1.7.2

1.7.1

1.7.4

13

14

2.1

U.S. EPA.



Integrated

Risk Information System (IRIS) (U.S. EPA, 1995a) Health Effects Assessment Summary Tables (HEAST)

(U.S. EPA, 1995b)

15

2.2



1) Hazard Quotient (HQ)

< 1.0

2) Cancer Risk (Rc)

< 10-6 ( < 10-4 10-6)



(Toxicity Endpoint)

2.3

2.4


2.4.1
(Commercial/Industrial) 3

2.4.2 4

2.4.3
5


16

2.1

2.1

2.1

17

2.1



1)



2)

18

5 1) 2)

3) 4)

5)

3.1


3.1



1) Oral Cancer Slope Factor (SFo)

Noncancer Reference Dose (RfDs)



2) Unit Risk Factors (URFs)

Reference Concentrations (RfCs)



3)

Drinking Water Standards (MCLs) Drinking Water

Health-Based Levels (HBLs) U.S. EPA

19


3.1 Integrated Risk Information System (IRIS) (U.S. EPA, 1995a) Health

Effects Assessment Summary Tables (HEAST) (U.S. EPA, 1995b) 3.1

20

HEAST The EPA Superfund Health Effects Assessment Summary Tables



(http://rais.ornl.gov/cgi-bin/tox/TOX_select?select=chem)
CalEPA California Environmental Protection Agency

(http://www.oehha.ca.gov/risk/chemicalDB/index.asp)
ATSDR The Agency for Toxic Substances and Disease Registry

(http://www.atsdr.cdc.gov/mrls/index.html)

83-32-9
67-64-1
309-00-2
120-12-7
7440-36-0
7440-38-2
1332-21-4
7440-39-3
56-55-3
71-43-2
205-99-2
207-08-9
65-85-0
50-32-8
7440-41-7
111-44-4
117-81-7
75-27-4
75-25-2

71-36-3
85-68-7
7440-43-9
86-74-8
75-15-0
56-23-5
57-74-9
106-47-8

Acenaphthene
Acetone (2-Propanone)
Aldrin
Anthracene
Antimony
Arsenic
Asbestos
Barium
Benz(a)anthracene
Benzene
Benzo(b)fluoranthene
Benzo(k)fluoranthene
Benzoic acid
Benzo(a)pyrene
Beryllium
Bis(2-chloroethyl)ether
Bis(2-ethylhexyl)phthalate
Bromodichloromethane
Bromoform
(tribromomethane)
Butanol
Butyl benzyl phthalate
Cadmium
Carbazole
Carbon disulfide
Carbon tetrachloride
Chlordane
p - Chloroaniline





6.00E-03
5.00E-02

2.00E+00

5.00E-03



2.00E-04
4.00E-03

6.00E-03
1.00E-01
1.00E-01



5.00E-03


5.00E-03
2.00E-03

MCL



3


3
3





3
3

3

3



3
3

3
3
3

4.00E+00
7.00E+00

4.00E-03
4.00E+00


1.00E-01

2.00E+00
4.00E+00
5.00E-06
1.00E+01




1.00E-04

1.00E-04
1.00E-03
1.00E+02


8.00E-05


HBL

RfD
RfD

SFo
RfD


RfD

RfD
RfD
SFo
RfD




SFo

SFo
SFo
RfD


SFo


D
C

B2

B2
B2




2.00E-02

1.30E-01
1.30E+00




2

1
1

C
B1


B2
B2

D


1.80E-03

5.70E-06
1.50E-05
3.70E-04


1

9
1
1

1.00E-01
2.00E-01
1.00E-03

1.00E-01
7.00E-04
6.00E-05
4.00E-03

... ()

1
1.4E+01
9
1
7.0E-01
9
1



1
7.00E-01
1
1


1


1
1.40E-02
9

Cancer Slope Factor


Unit Risk Factor
Reference Dose
Reference Concentration
(SFo)C
(URF)D
(RfD)E
(RfC)F
(-/)
(/)
(/-)
(/)
Carc.
SFo
G Carc.
URF
G
RfD
G
RfC
G
H
H
Class
Class






6.00E-02
1
2.10E-01
9
D


D


1.00E-01
1
3.5E-01
9
B2 1.70E+01
1
B2
4.90E-03
1
3.00E-05
1


D


D


3.00E-01
1








4.00E-04
1


A
1.50E+00
1
A
4.30E-03
1
3.00E-04
1





A
2.3E+05
8



B2


7.00E-02
1
5.00E-04
2
B2
7.30E-01
4
A
8.30E-06
1




A
2.90E-02
1
B2
7.80E-06
10




B2
7.30E-01
4
B2
2.1E-04
9




B2
7.30E-02
4

2.1E-05
9







B2


4.00E+00
1


B2 7.30E+00
1
B2
2.40E-03
1




B2 4.30E+00
1
B2
3.30E-04
1
5.00E-03
1


B2 1.10E+00
1
B2






B2
1.40E-02
1
B2
4.0E-06
9
2.00E-02
1


B2
6.20E-02
1
B2
1.10E-06
1
2.00E-02
1


B2
7.90E-03
1
D


2.00E-02
1

Asbestos /

CAS
Number

Maximum Contaminant Water Health Based


Level (MCL)A
Limits (HBL)B
(/)
(/)

3.1

21

22

Chlorobenzene
Chlorodibromomethane
Chloroform
2-Chlorophenol
Chromium
Chromium (III)
Chromium (VI)
Chrysene
Cyanide
DDD
DDE
DDT
Dibenz(a,h)anthracene
Di-n-butyl phthalate
1,2-Dichlorobenzene
1,4-Dichlorobenzene
3,3-Dichlorobenzidine
1,1-Dichloroethane
1,2-Dichloroethane
1,1-Dichloroethylene
cis-1,2-Dichloroethylene
trans-1,2-Dichloroethylene
2,4-Dichlorophenol
1,2-Dichloropropane
1,3-Dichloropropene
Dieldrin
Diethyl phthalate
2,4-Dimethylphenol
2,4-Dinitrophenol
2,4-Dinitrotoluene**
2,6-Dinitrotoluene**
Di-n-octyl phthalate
Endosulfan

108-90-7
124-48-1
67-66-3
95-57-8
7440-47-3
16065-83-1
18540-29-9
218-01-9
57-12-5
72-54-8
72-55-9
50-29-3
53-70-3
84-74-2
95-50-1
106-46-7
91-94-1
75-34-3
107-06-2
75-35-4
156-59-2
156-60-5
120-83-2
78-87-5
542-75-6
60-57-1
84-66-2
105-67-9
51-28-5
121-14-2
606-20-2
117-84-0
115-29-7

CAS
Number

1.00E-01
1.00E-01
1.00E-01

1.00E-01

1.00E-01

2.00E-01





6.00E-01
7.50E-02


5.00E-03
7.00E-03
7.00E-02
1.00E-01

5.00E-03








MCL

3
3
3

3

3

3





3
3


3
3
3
3

3











2.00E-01

4.00E+01

1.00E-02

4.00E-04
3.00E-04
3.00E-04
1.00E-05
4.00E+00


2.00E-04
4.00E+00




1.00E-01

5.00E-04
5.00E-06
3.00E+01
7.00E-01
4.00E-02
1.00E-04
1.00E-04
7.00E-01
2.00E-01

HBL




RfD

RfD

SFo

SFo
SFo
SFo
SFo
RfD


SFo
RfD




RfD

SFo
SFo
RfD
RfD
RfD
SFo
SFo
RfD
RfD

Maximum Contaminant Water Health Based


Level (MCL)A
Limits (HBL)B
(/)
(/)

... ()

Reference Dose
Cancer Slope Factor
Unit Risk Factor
Reference Concentration
(RfD)E
(SFo)C
(URF)D
(RfC)F

(-/)
(/)
(/-)
(/)
Carc.
SFo
G Carc.
URF
G
RfD
G
RfC
G
ClassH
ClassH
D


C


2.00E-02
1
2.00E-02
2
C
8.40E-02
1
B2
2.30E-05
1
2.00E-02
1


B2
6.10E-03
1
B2


1.00E-02
1








5.00E-03
1
1.80E-02
9
A


A
1.20E-02
1
5.00E-03
1








1.00E+00
1


A


A
1.20E-02
1
5.00E-03
1


B2
7.30E-03
4

2.10E-06
9




D


D


2.00E-02
1


B2
2.40E-01
1
B2
6.90E-05
9




B2
3.40E-01
1
B2
3.40E-01
9




B2
3.40E-01
1
B2
9.70E-05
1
5.00E-04
1


B2 7.30E+00
4
B2
2.10E-03
9




D


D


1.00E-01
1
3.50E-01
9
D


D


9.00E-02
1
2.00E-01
2
B2
2.40E-02
2
B2




8.00E-01
1
B2
4.50E-01
1
B2
1.30E-04
9




C


C


1.00E-01
7
5.00E-01
2
B2
9.10E-02
1
B2
2.60E-05
1




C
6.00E-01
1
C
5.00E-05
1
9.00E-03
1


D


D


1.00E-02
2
3.50E-02
9






2.00E-02
1
7.00E-02
9






3.00E-03
1
1.10E-02
9
B2
6.80E-02
2
B2




4.00E-03
1
B2
1.80E-01
2
B2
3.70E-05
2
3.00E-04
1
2.00E-02
1
B2 1.60E+01
1
B2
4.60E-03
1
5.00E-05
1


D


D


8.00E-01
1
2.80E+00
9






2.00E-02
1
7.00E-02
9






2.00E-03
1
7.00E-03
9
B2
6.80E-01
1

1.90E-04
9
2.00E-03
1


B2
6.80E-01
1

1.90E-04
9
1.00E-03
2








2.00E-02
2
7.00E-02
9






6.00E-03
2
2.10E-02
9

... ()

Endrin
Ethylbenzene
Fluoranthene
Fluorene
Heptachlor
Heptachlor epoxide
Hexachlorobenzene
Hexachloro-1,3-butadiene
-HCH (-BHC)
-HCH (-BHC)
-HCH (Lindane)
Hexachlorocyclopentadiene
Hexachloroethane
Indeno(1,2,3-cd)pyrene
Isophorone
Lead
Mercury
Methoxychlor
Methyl bromide
Methylene chloride
2-Methylphenol (o-cresol)
Naphthalene
Nickel
Nitrobenzene
N-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
Pentachlorophenol
Phenol
Pyrene
Selenium
Silver

2.00E-03
7.00E-01


4.00E-04
2.00E-04
1.00E-03
1.00E-03


2.00E-04
5.00E-02



1.50E-02
2.00E-03
4.00E-02

5.00E-03






1.00E-03


5.00E-02

MCL

3
3


3
3
3
3


3
3



11
3
3

3






3


3



1.00E+00
1.00E+00



1.00E-03
1.00E-05
5.00E-05


6.00E-03
1.00E-04
9.00E-02



5.00E-02

2.00E+00
1.00E+00
1.00E-01
2.00E-02
2.00E-02
1.00E-05

2.00E+01
1.00E+00

2.00E-01

HBL



RfD
RfD



SFo
SFo
SFo


SFo
SFo
SFo



RfD

RfD
RfD
HA
RfD
SFo
SFo

RfD
RfD

RfD

Health Advisory (HA) EPA Office of Science and Technology, 7/10/95.

72-20-8
100-41-4
206-44-0
86-73-7
76-44-8
1024-57-3
118-74-1
87-68-3
319-84-6
319-85-7
58-89-9
77-47-4
67-72-1
193-39-5
78-59-1
7439-92-1
7439-97-6
72-43-5
74-83-9
75-09-2
95-48-7
91-20-3
7440-02-0
98-95-3
86-30-6
621-64-7
87-86-5
108-95-2
129-00-0
7782-49-2
7440-22-4

... ()

Cancer Slope Factor


Unit Risk Factor
Reference Dose
Reference Concentration
(SFo)C
(URF)D
(RfD)E
(RfC)F
(-/)
(/)
(/-)
(/)
Carc.
SFo
G Carc.
URF
G
RfD
G
RfC
G
H
H
Class
Class
D


D


3.00E-04
1
1.10E-03
9
D


D


1.00E-01
1
1.00E+00
1
D


D


4.00E-02
1
1.40E-01
9
D





4.00E-02
1
1.40E-01
9
B2 4.50E+00
1
B2
1.30E-03
1
5.00E-04
1


B2 9.10E+00
1
B2
2.60E-03
1
1.30E-05
1


B2 1.60E+00
1
B2
4.60E-04
1
8.00E-04
1


C
7.80E-02
1
C
2.20E-05
1
2.00E-04
2


B2 6.30E+00
1
B2
1.80E-03
1




C
1.80E+00
1
C
5.30E-04
1




B2 1.30E+00
2
C
3.70E-04
9
3.00E-04
1


D


D


7.00E-03
1
7.00E-05
2
C
1.40E-02
1
C
4.00E-06
1
1.00E-03
1


B2
7.30E-01
4
B2
2.10E-04
9




C
9.50E-04
1
C
2.70E-07
9
2.00E-01
1












D


D


3.00E-04
2
3.00E-04
2
D


D


5.00E-03
1
1.80E-02
9
D


D


1.40E-03
1
5.00E-03
1
B2
7.50E-03
1
B2
4.70E-07
1
6.00E-02
1
3.00E+00
2
C


C


5.00E-02
1
1.80E-01
9
D


D


4.00E-02
6
1.40E-01
9
A


A
2.40E-04
1
2.00E-02
1


D


D


5.00E-04
1
2.00E-03
2
B2
4.90E-03
1
B2
1.40E-06
9




B2 7.00E+00
1
B2
2.00E-03
9




B2
1.20E-01
1
B2
3.40E-05
9
3.00E-02
1


D


D


6.00E-01
1
2.10E+00
9
D


D


3.00E-02
1
1.10E-01
9
D


D


5.00E-03
1


D


D


5.00E-03
1

CAS
Number

Maximum Contaminant Water Health Based


Level (MCL)A
Limits (HBL)B
(/)
(/)

... ()

23

24

100-42-5
79-34-5
127-18-4
7440-28-0
108-88-3
8001-35-2
120-82-1
71-55-6
79-00-5
79-01-6
95-95-4
88-06-2
7440-62-2
108-05-4
75-01-4

108-38-3
95-47-6
106-42-3
1330-20-7
7440-66-6

Styrene
1,1,2,2-Tetrachloroethane
Tetrachloroethylene
Thallium
Toluene
Toxaphene
1,2,4-Trichlorobenzene
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Trichloroethylene
2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
Vanadium
Vinyl acetate
Vinyl chloride
(chloroethene)
m-Xylene
o-Xylene
p-Xylene
Xylene (Total)
Zinc

1.00E-01

5.00E-03
2.00E-03
1.00E+00
3.00E-03
7.00E-02
2.00E-01
5.00E-03
5.00E-03




2.00E-03

1.00E+01
1.00E+01
1.00E+01
1.00E+01

MCL


4.00E-04








4.00E+00
8.00E-03
3.00E-01
4.00E+01





1.00E+01

3
3
3
3

HBL

3

3
3
3
3
3
3
3
3




3





RfD


SFo








RfD
SFo
RfD
RfD

D
D
D
D
D

D
D
D
D
D

2.00E+00
2.00E+00
2.00E+00
2.00E+00
3.00E-01

2
2
1
2
1

7.00E+00
7.00E+00
7.00E+00

A
B

Maximum Contaminant Level (MCL) : U.S. EPA. Safe Drinking Water Act
Water Health Based Limits (HBL) : 30 10-6 = 1

9
9
9

Cancer Slope Factor


Unit Risk Factor
Reference Dose
Reference Concentration
(SFo)C
(URF)D
(RfD)E
(RfC)F

(-/)
(/)
(/-)
(/)
G
G
Carc.
SFo
Carc.
URF

RfD
G
RfC
G
ClassH
ClassH






2.00E-01
1
1.00E+00
1
C
2.00E-01
1
C
5.80E-05
1





5.20E-02
5

5.80E-07
5
1.00E-02
1












D


D


2.00E-01
1
4.00E-01
1
B2 1.10E+00
1
B2
3.20E-04
1




D


D


1.00E-02
1
2.00E-01
2
D


D




1.00E+00
5
C
5.70E-02
1
C
1.60E-05
1
4.00E-03
1



1.10E-02
5

1.70E-06
5










1.00E-01
1
3.50E-01
9
B2
1.10E-02
1
B2
3.10E-06
1










7.00E-03
2








1.00E+00
1
2.00E-01
1
A
1.90E+00
2
A
8.40E-05
2



Tetrachloroethylene Perchloroethylene (PCE) Trichloroethylene (TCE) U.S. EPA.


International Agency for Research on Cancer (IARC) (probable carcinogenic to humans)

CAS
Number

Maximum Contaminant Water Health Based


Level (MCL)A
Limits (HBL)B
(/)
(/)

... ()

Cancer Slope Factor (SF) :

1 10-6 Oral Cancer Slope Factor (SFo)


Unit Risk Factor (URF) : 1


Reference Dose (RfD) :

RfD
Reference Concentration (RfC) :


:

1 IRIS, U.S. EPA (1995a)
2 HEAST, U.S. EPA (1995b)



3 U.S. EPA (1995a)
4 OHEA, U.S. EPA (1993c)



5 Interim toxicity criteria provided by Superfund Health Risk Technical Support Center,
6 ECAO, U.S. EPA (1994b)
Environmental Criteria Assessment Office Group (ECAO), Cincinnati, OH (1994)
7 ECAO, U.S. EPA (1994c)
8 U.S. EPA (2004a)
9 U.S. EPA (1995b) Appendix B
10 U.S. EPA. (1999b) Integrated Risk Information System (IRIS). http://www.epa.gov/iris. National Center for Environmental Assessment, Washington, DC.
11 http://water.epa.gov/drink/contaminants/index.cfm#List

U.S. EPA.:
Group A : (human carcinogen)
Group B : (probable human carcinogen)
B1 : (limited evidence from epidemiologic studies)
B2 :

(sufficient evidence from animal studies and inadequate evidence or no data from epidemiologic studies)
Group C : (possible human carcinogen)
Group D : (not classifiable as to health carcinogenicity)
Group E : (evidence of non-carcinogenicity for humans)

C


D

E

F

G






25

3.2

3.2


3.2

(/)
()
(/)
(/)
()
()

225
25
100
14.4
65
71

5 45 (1 52 )

U.S. EPA. (2001)

(Tidal Volume, TV) - 500

(respiratory rate) 16 - 20 / 20 / 1

14.4 / ( 8)

17 - 29 ( http://www.

sizethailand.org/information.html) U.S. EPA (1991b) 70

71 ( 75 68 ) ( , 2549)

26

3.3

3.3.1






(1)

(/)
=

(1)



(2)

(/)
=
(2)




Particulate Emission Factor (PEF)

U.S. EPA. (1996b) Connor et al. (1994) Cowherd et al. (1985)

7 (3)


(PEF) =
(3)

(/)


(Default) 3.3

27

3.3



1.0

THQ Target Hazard Quotient



RfC Inhalation Reference
Concentration
URF Inhalation Unit Risk Factor
AT Averaging Time


EF Exposure Frequency
ED Exposure Duration
P Emission Coefficient

Um Mean Annual Wind Speed
Ut Equivalent Wind Speed at
7 Meter Height
V Fraction of Vegetation Cover
F(x) Function Dependent on
Ut / Um


/


25


71


/
225


25


/- 70.0 ( )

/


/
0.708 ( )

/
0.808 ( )
7


-
0.5
Ut / Um
-
1.60 ( )

1,600 ( 400 )

0.5

28


(4)
(/)
=

(4)


(5)
(/)
=

(5)



Volatilization Factor (VF)

U.S. EPA. (1996b) Connor et al. (1994)

(Chamber)

3.1 (6) - (10)

3.1

Connor et al. (1994)


(VF) (/)

(6)

(7)

(8)

(9)

(10)

(Default) 3.4

29

3.4

VF

THQ Target Hazard Quotient

RfC Inhalation Reference
Concentration
URF Inhalation Unit Risk Factor
AT Averaging Time

EF Exposure Frequency
ED Exposure Duration
P Emission Coefficient

T Averaging Time for
Vapor Flux
Da Apparent Diffusivity
a Air-Filled Soil Porosity
w Air-Filled Soil Porosity
n Total Porosity
b Dry Soil Bulk Density
S Soil Particle Density
Di Diffusivity in Air

Dw Diffusivity in Water

H Dimensionless Henrys
Law Constant
Kd Soil-Water Partitioning
Coefficient
Kow Octanol-water Partitioning
Coefficient
oc Soil Organic Carbon
Content

1.0


/





/



/-
/




/

-

-

-

/

/

/

( )

/

( )

-



/



-



-


25
71
225
25
70.0
1.15 x 109

0.28
0.15
0.43
1,500
2,650



( )

( )

( )
0.006

25
U.S. EPA (1996b) b S 1,500 2,650 /

U.S. EPA (1996b) a , w n 0.28, 0.15 0.43

U.S. EPA (1996b) oc 0.006 ( 0.6 )

pH pH 7

30



(4) (5) 3.5.2

U.S. EPA. (1996b) Connor et al. (1994)

3.2 (11)

3.2

Connor et al. (1994)

(VF) (/)

(11)

(Default) (11) 3.5

31

3.5 (11)



Uair Wind Speed Above Ground


/
Surface at air
air




air Air Mixing Zone Height in the

Breathing Zone


(

3.1 )

W Width of Source Area Parallel

to Wind, or Groundwater Flow
Direction


T Averaging Time for


Vapor Flux


b Dry Soil Bulk Density

/


ds Average Source Depth


0.708 (

)
2.0

40

1.15 x 109
1,500
3.00

40
U.S. EPA (1996b) b 1,500 /




3.00


Saturation

Limit (Csat)

Non-aqueous Phase Liquid (NAPL) (

NAPL )

(Saturation Limit)

32

(Csat)
(/)

(Default) (12) 3.6

(12)

3.6 (14)


Csat Soil Saturation Concentration
S Solubility in Water
Kd Soil-Water Partitioning
Coefficient
Koc Soil-Organic Carbon
Partitioning Coefficient
b Dry Soil Bulk Density
oc Soil Organic Carbon Content
w Air-Filled Soil Porosity
a Air-Filled Soil Porosity


/

/
/


/



/

-

-

-


H Dimensionless Henrys Law
-
Constant





(10)

1,500
0.006
0.15
0.28

3.5.2 3.5.3



(Saturation Limit)

(VF)

(Saturation Limit, Csat)


(13)


(/)


RfDABS (/-)

(13)

(14)

(Default) 3.7

33

3.7



THQ Target Hazard Quotient




RfDo Oral Reference Dose
RfDABS Dermally-Adjusted

Reference Dose
BW Body Weight
AT Averaging Time


EF Exposure Frequency
ED Exposure Duration
AF Skin-Soil Adherence Factor


ABSd Dermal Absorption Factor


-


/ -

/ -








/



/

-

-

EV Event Frequency


()



SA Skin Surface Area


1.0

(14)
70
25
225
25
0.2

( 3.10)

18,000

AT

3.8 (14) RfDABS







RfDo Oral Reference Dose

ABSGI Gastro-Intestinal Absorption Factor



3.1

34

/ -
-


1
( 3.15)

3.9 Gastro-Intestinal Absorption Factor Dermally-Adjusted Reference Dose


CAS Number

(%)

ABSGI

80
70 - 90
> 90
76 - 100
58 - 89
> 50

0.8
0.9
1.0
1.0
0.9
1.0

95
2.5 - 5

1.0
0.025

57-74-9
50-29-3
94-75-7
87-86-5
-
-

7440-38-2
7440-43-9

Chlordane
DDT
2,4-Dichlorophenoxyacetic acid
Pentachlorophenol
Polycyclic aromatic hydrocarbons (PAHs)


Arsenic
Cadmium

1.0
: U.S. EPA. (2001)

3.10 (ABSd) (13) (15)





CAS Number

ABSd

0.04
0.03
0.05
0.04
0.25
0.13
0.10

U.S. EPA. (2001)


Wester et al. (1990)
U.S. EPA. (2001)
Kissel et al. (1996)
Wester et al. (1993)
Wester et al. (1990)
U.S. EPA. (2001)

0.03
0.001

U.S. EPA. (2001)


U.S. EPA. (2001)

57-74-9
50-29-3
94-75-7
58-89-9
87-86-5
-
-

7440-38-2
7440-43-9

Chlordane
DDT
2,4-Dichlorophenoxyacetic acid
Lindane
Pentachlorophenol
Polycyclic aromatic hydrocarbons (PAHs)


Arsenic
Cadmium

0.1




=
(/)

(15)

(Default) 3.11

35

3.11 (15)




TR Target Cancer Risk
AT Averaging Time


EF Exposure Frequency
SFABS Dermally-Adjusted Cancer

Slope Factor
SFS Age-Adjusted Dermal Factor
ABSd Dermal Absorption Factor


EV Event Frequency


SFo Oral Slope Factor


-





/

-/



-/-

-



/
()


-/


10-6
71
225
(16)
(17)

3.10
1

AT
3.1

SFABS (-/)

(16)

(Default) 3.12

3.12 SFABS


SFo Oral Slope Factor
ABSGI Gastro-Intestinal Absorption Factor


-/
-


1
( 3.9)

3.1


SFS

(-/-)

36

(Default) 3.13

(17)

3.13 (17)


SFS Age-Adjusted Dermal Factor
SA Skin Surface Area
ED Exposure Duration During
AF Skin-Soil Adherence Factor-

Adult
BW Average Body Weight


-/-





/

-


153*
18,000
25
0.07
70

* 3.18

3.3.2

MCL

Reference Dose Slope Factor

MCL HBL ( 3.1) MCL HBL

(18)

(/)

(18)

(19)

(/)

(19)

(Default) 3.14

37

3.14



-

-
/-
-/



/

-

/

1.0


THQ Target Hazard Quotient


TR Target Cancer Risk
RfDo Oral Reference Dose
SFo Oral Slope Factor
BW Body Weight
AT Averaging Time


EF Exposure Frequency
ED Exposure Duration
IF Ingestion Fraction


IR Water Ingestion Rate

10-6


70
25
71
225
25

0.7
5.0

U.S. EPA (1989)

38

3.4

3.3 3.4



3.1


(PEF)
(3)

(VF)
(6) - (10)


(VF)
(11)



PEF
(1) (2)



VF
(4) (5)



VF
(4) (5)


(Csat)
(12) VF






RfDABS
(14)
SFABS
(16)
ABSGI

3.9
ABSd

3.10


RfDABS
ABSd (13)

SFABS
ABSd (15)

Csat
Csat Csat

Csat

3.3

39




3.1




(18) (19)


MCL HBL MCL HBL
MCL HBL

MCL HBL MCL HBL
RfD SF MCL HBL



3.4

40

3 U.S. EPA



RfD RfC (U.S EPA 1999 U.S EPA 2010)

U.S. EPA (1996d)



1)

(PbBadult, 0)



2)

Linear Biokinetic Slope Factor BKSF




3)


4)

5) 200 / ( 0.2 /)

41

(/ /)

(Default) 4.1

(20)

4.1 (20)

PbBgoal Goal of lead



/
10.0

concentration in

(/)

blood

/
3.25
PbBadult,0 Initial Blood Lead

Concentration in the
(/)

Absence of Site


Exposure


AT Averaging Time


33




BSKF Biokinetic Slope Factor Relating Increase in Typical Adult /
0.4

Blood Lead Concentration to Average Daily Lead Uptake (



) /



()

IR Ingestion Rate of Soil
/
0.20





EF Exposure Frequency

/
255
AS Absorption Factor

-
0.12
(U.S. EPA., 1994d)

40 ()
ACGIH = 30 ()

Sirivarasai et al. (2002) 3.25 / .. 2545


Wananukul et al. (1998) 5.95 + 2.01 /

Pocock et al. (1983) Sherlock et al. (1984)

U.S. EPA. (1994d) absorption factor 0.20 relative bioavailability

0.6

42

()

25 (.. 2547) 20 (.. 2543)

.. 2535 5.2

43

5.1


(/)

(/)
CAS
Number

44

83-32-9
67-64-1
309-00-2
120-12-7
7440-36-0
7440-38-2
1332-21-4
7440-39-3
56-55-3
71-43-2
205-99-2
207-08-9
65-85-0
50-32-8
7440-41-7
111-44-4
117-81-7
75-27-4
75-25-2

71-36-3
85-68-7
7440-43-9
86-74-8
75-15-0
56-23-5
57-74-9
106-47-8
108-90-7
124-48-1
67-66-3
95-57-8
7440-47-3
16065-83-1
18540-29-9
218-01-9
57-12-5
72-54-8

Acenaphthene
Acetone (2-Propanone)
Aldrin
Anthracene
Antimony
Arsenic
Asbestos
Barium
Benz (a) anthracene
Benzene
Benzo (b) fluoranthene
Benzo (k) fluoranthene
Benzoic acid
Benzo (a) pyrene
Beryllium
Bis (2-chloroethyl) ether
Bis (2-ethylhexyl) phthalate
Bromodichloromethane
Bromoform
(tribromomethane)
Butanol
Butyl benzyl phthalate
Cadmium
Carbazole
Carbon disulfide
Carbon tetrachloride
Chlordane
p - Chloroaniline
Chlorobenzene
Chlorodibromomethane
Chloroform
2-Chlorophenol
Chromium
Chromium (III)
Chromium (VI)
Chrysene
Cyanide
DDD

4.43 X 106
7.38 X 106
1.22 X 101
- - -
- - -
1.39 X 101
2.61 X 10-4
1.05 X 104
7.22 X 103
7.67 X 103
2.85 X 102
2.85 X 103
- - -
2.50 X 101
1.82 X 102
- - -
1.50 X 104
5.45 X 104
- - -

2.95 X 108
3.33 X 101
- - -
1.05 X 104
1.48 X 107
1.62 X 102
- - -
2.95 X 105
4.22 X 105
2.61 X 103
- - -
3.80 X 105
4.99 X 10
- - -
4.99 X 10
2.85 X 104
- - -
8.68 X 102

2.12 X 105
3.55 X 106
2.62 X 105
- - -
- - -
- - -
- - -
- - -
2.83 X 104
8.20 X 104
1.43 X 104
7.61 X 103
- - -
1.25 X 104
- - -
- - -
4.07 X 107
1.60 X 106
- - -

1.54 X 103
2.57 X 103
4.25 X 10-3
- - -
- - -
- - -
- - -
- - -
2.51
2.67
9.92 X 10-2
9.92 X 10-1
- - -
8.68 X 10-3
- - -
- - -
5.21
1.89 X 10
- - -

1.31 X 104
2.43 X 104
1.51 X 10-1
6.55 X 104
9.71 X 10
5.69
- - -
1.70 X 104
2.43
8.83 X 10
2.43
2.43 X 10
9.71 X 105
2.43 X 10-1
4.58 X 10-1
2.33
1.83 X 102
4.13 X 10
3.24 X 102

1.54 X 103
2.57 X 103
4.25 X 10-3
6.55 X 104
9.71 X 10
5.69
2.61 X 10-4
1.05 X 104
2.43
2.67
9.92 X 10-2
9.92 X 10-1
9.71 X 105
8.68 X 10-3
4.58 X 10-1
2.33
5.21
1.89 X 10
3.24 X 102

2.00
4.00
5.42 X 10-6
1.00 X 10
1.30 X 10-2
5.00 X 10-2
--2.27
1.26 X 10-4
5.00 X 10-3
1.26 X 10-4
1.26 X 10-3
1.30 X 102
2.00 X 10-4
4.00 X 10-3
8.38 X 10-5
6.58 X 10-3
1.00 X 10-1
1.00 X 10-1

3.15 X 106
8.29 X 105
- - -
1.75 X 105
7.14 X 105
1.39 X 103
- - -
2.25 X 106
2.05 X 106
1.46 X 105
- - -
1.86 X 107
- - -
- - -
- - -
4.81 X 103
- - -
6.80 X 105

1.03 X 105
1.16 X 10-2
- - -
3.66
5.14 X 103
5.63 X 10-2
- - -
1.03 X 102
1.47 X 102
9.06 X 10-1
- - -
1.32 X 102
- - -
- - -
- - -
9.92
- - -
3.02 X 10-1

2.43 X 104
4.85 X 104
6.07
1.28 X 102
2.43 X 104
1.97 X 10
3.94
9.71 X 102
4.85 X 103
3.05 X 10
4.20 X 102
1.21 X 103
1.21 X 103
2.43 X 105
1.21 X 103
2.43 X 102
4.85 X 103
1.07 X 10

2.43 X 104
1.16 X 10-2
6.07
3.66
5.14 X 103
5.63 X 10-2
3.94
1.03 X 102
1.47 X 102
9.06 X 10-1
4.20 X 102
1.32 X 102
4.99
2.43 X 105
4.99
9.92
4.85 X 103
3.02 X 10-1

4.00
7.00
3.24 X 10-2
4.61 X 10-3
4.00
5.00 X 10-3
2.00 X 10-3
1.30 X 10-1
6.49 X 10-1
1.00 X 10-1
1.00 X 10-1
2.00 X 10-1
1.62 X 10-1
4.00 X 10
1.62 X 10-1
1.26 X 10-2
6.49 X 10-1
4.00 X 10-4
... ()

... ()

(/)

(/)
CAS
Number


72-55-9 DDE

50-29-3 DDT

53-70-3 Dibenz (a, h) anthracene

84-74-2 Di-n-butyl phthalate

95-50-1 1, 2-Dichlorobenzene
106-46-7 1, 4-Dichlorobenzene

91-94-1 3, 3-Dichlorobenzidine

75-34-3 1, 1-Dichloroethane
107-06-2 1, 2-Dichloroethane

75-35-4 1, 1-Dichloroethylene
156-59-2 cis-1, 2-Dichloroethylene
156-60-5 trans-1, 2-Dichloroethylene
120-83-2 2, 4-Dichlorophenol

78-87-5 1, 2-Dichloropropane
542-75-6 1, 3-Dichloropropene

60-57-1 Dieldrin

84-66-2 Diethyl phthalate
105-67-9 2, 4-Dimethylphenol

51-28-5 2, 4-Dinitrophenol
121-14-2 2, 4-Dinitrotoluene
606-20-2 2, 6-Dinitrotoluene
117-84-0 Di-n-octyl phthalate
115-29-7 Endosulfan

72-20-8 Endrin
100-41-4 Ethylbenzene
206-44-0 Fluoranthene

86-73-7 Fluorene

76-44-8 Heptachlor
1024-57-3 Heptachlor epoxide
118-74-1 Hexachlorobenzene

87-68-3 Hexachloro-1,3-butadiene
319-84-6 a-HCH (a-BHC)
319-85-7 b-HCH (b-BHC)

58-89-9 g-HCH (Lindane)

77-47-4 Hexachlorocyclopentadiene

67-72-1 Hexachloroethane
193-39-5 Indeno (1, 2 ,3-cd) pyrene

78-59-1 Isophorone

1.76 X 10-1
6.18 X 102
2.85 X 101
7.38 X 106
4.22 X 106
1.69 X 107
4.61 X 102
1.05 X 107
2.30 X 103
1.20 X 103
7.38 X 105
1.48 X 106
2.32 X 105
8.44 X 104
1.62 X 103
1.30 X 10
5.91 X 107
1.48 X 106
1.48 X 105
3.15 X 102
3.15 X 102
1.48 X 106
4.43 X 105
2.32 X 104
2.11 X 107
2.95 X 106
2.95 X 106
4.61 X 10
2.30 X 10
1.30 X 102
2.72 X 103
3.33 X 10
1.13 X 102
1.62 X 102
1.48 X 103
1.50 X 104
2.85 X 102
2.22 X 105

1.35 X 104
5.08 X 105
7.32 X 104
2.74 X 106
2.52 X 106
1.16 X 106
6.04 X 104
1.87 X 106
2.25 X 104
5.21 X 103
1.52 X 106
4.44 X 106
3.99 X 107
9.98 X 105
8.82 X 103
2.54 X 105
2.05 X 106
1.08 X 107
8.99 X 105
1.66 X 105
8.10 X 104
1.38 X 107
3.85 X 104
1.72 X 105
1.40 X 106
1.63 X 105
1.93 X 105
3.22 X 105
1.20 X 105
2.46 X 105
5.87 X 105
7.57 X 104
9.30 X 103
2.19 X 105
6.35 X 105
3.00 X 106
5.90 X 102
3.61 X 106

6.13 X 10-5
2.15 X 10-1
9.92 X 10-3
2.57 X 103
1.47 X 103
5.87 X 103
1.60 X 10-1
3.67 X 103
8.02 X 10-1
4.17 X 10-1
2.57 X 102
5.14 X 102
8.07 X 10
2.94 X 10
5.63 X 10-1
4.53 X 10-3
2.05 X 104
5.14 X 102
5.14 X 10
1.10 X 10-1
1.10 X 10-1
5.14 X 102
1.54 X 102
8.07
7.34 X 103
1.03 X 103
1.03 X 103
1.60 X 10-2
8.02 X 10-3
4.53 X 10-2
9.47 X 10-1
1.16 X 10-2
3.93 X 10-2
5.63 X 10-2
5.14 X 10-1
5.21
9.92 X 10-2
7.72 X 10

7.53
2.26 X 10
2.43 X 10-1
2.43 X 104
2.18 X 104
1.07 X 102
5.69
2.43 X 104
2.81 X 10
4.27
2.43 X 103
4.85 X 103
7.28 X 102
3.76 X 10
1.42 X 10
1.60 X 10-1
1.94 X 105
4.85 X 103
4.85 X 102
3.76
3.76
4.85 X 103
1.46 X 103
7.28 X 10
2.43 X 104
8.74 X 103
8.74 X 103
5.69 X 10-1
2.81 X 10-1
1.60
3.28 X 10
4.06 X 10-1
1.42
4.92
1.70 X 103
1.83 X 102
2.43
2.69 X 103

6.13 X 10-5
2.15 X 10-1
9.92 X 10-3
2.57 X 103
1.47 X 103
1.07 X 102
1.60 X 10-1
3.67 X 103
8.02 X 10-1
4.17 X 10-1
2.57 X 102
5.14 X 102
8.07 X 10
2.94 X 10
5.63 X 10-1
4.53 X 10-3
2.05 X 104
5.14 X 102
5.14 X 10
1.10 X 10-1
1.10 X 10-1
5.14 X 102
1.54 X 102
8.07
7.34 X 103
1.03 X 103
1.03 X 103
1.60 X 10-2
8.02 X 10-3
4.53 X 10-2
9.47 X 10-1
1.16 X 10-2
3.93 X 10-2
5.63 X 10-2
5.14 X 10-1
5.21
9.92 X 10-2
7.72 X 10

3.00 X 10-4
3.00 X 10-4
1.26 X 10-5
4.00
2.92
7.50 X 10-2
2.05 X 10-4
4.00
5.00 X 10-3
7.00 X 10-3
3.24 X 10-1
6.49 X 10-1
1.00 X 10-1
5.00 X 10-3
5.12 X 10-4
5.76 X 10-6
3.00 X 10
7.00 X 10-1
6.49 X 10-2
1.36 X 10-4
1.36 X 10-4
7.00 X 10-1
2.00 X 10-1
9.73 X 10-3
3.24
1.30
1.30
4.00 X 10-4
2.00 X 10-4
1.00 X 10-3
1.18 X 10-3
1.46 X 10-5
5.12 X 10-5
2.00 X 10-4
2.27 X 10-1
6.58 X 10-3
1.26 X 10-4
9.70 X 10-2
... ()

45

... ()

(/)

(/)
CAS
Number

46

7439-92-1
7439-97-6
72-43-5
74-83-9
75-09-2
95-48-7
91-20-3
7440-02-0
98-95-3
86-30-6
621-64-7
87-86-5
108-95-2
129-00-0
7782-49-2
7440-22-4
100-42-5
79-34-5
127-18-4
108-88-3
8001-35-2
120-82-1
71-55-6
79-00-5
79-01-6
95-95-4
88-06-2
7440-62-2
108-05-4
75-01-4

108-38-3
95-47-6
106-42-3
1330-20-7
7440-66-6

Lead
Mercury
Methoxychlor
Methyl bromide
Methylene chloride
2-Methylphenol (o-cresol)
Naphthalene
Nickel
Nitrobenzene
N-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
Pentachlorophenol
Phenol
Pyrene
Selenium
Silver
Styrene
1, 1, 2, 2-Tetrachloroethane
Tetrachloroethylene
Toluene
Toxaphene
1, 2, 4-Trichlorobenzene
1, 1, 1-Trichloroethane
1, 1, 2-Trichloroethane
Trichloroethylene
2, 4, 5-Trichlorophenol
2, 4, 6-Trichlorophenol
Vanadium
Vinyl acetate
Vinyl chloride
(chloroethene)
m-Xylene
o-Xylene
p-Xylene
Xylene (Total)
Zinc

- - -
6.33 X 103
3.80 X 105
1.05 X 105
2.11 X 107
3.80 X 106
3.71 X 106
2.50 X 102
4.22 X 104
4.28 X 104
3.00 X 10
1.76 X 103
4.43 X 107
2.32 X 106
- - -
- - -
2.11 X 107
1.03 X 103
1.03 X 105
8.44 X 106
1.87 X 102
4.22 X 106
2.11 X 107
3.74 X 103
3.52 X 104
7.38 X 106
1.93 X 104
- - -
4.22 X 106
7.13 X 102

1.48 X 108
1.48 X 108
1.48 X 108
1.48 X 108
- - -

- - -
2.27 X 104
3.85 X 104
3.53 X 105
6.55 X 105
1.52 X 107
4.26 X 105
- - -
8.68 X 105
3.04 X 105
7.09 X 103
8.21 X 107
1.50 X 107
1.04 X 105
- - -
- - -
1.62 X 106
5.93 X 104
5.61 X 105
1.82 X 106
1.40 X 106
1.08 X 105
1.06 X 104
8.59 X 103
9.87 X 103
4.54 X 107
1.15 X 107
- - -
6.47 X 105
1.36 X 103

- - -
2.20
1.32 X 102
3.67 X 10
3.55
1.32 X 103
1.03 X 103
- - -
1.47 X 10
1.49 X 10
1.04 X 10-2
6.13 X 10-1
1.54 X 104
8.07 X 102
- - -
- - -
7.34 X 103
3.59 X 10-1
3.59 X 10
2.94 X 103
6.51 X 10-2
1.47 X 103
4.24 X 103
1.30
1.23 X 10
2.57 X 103
6.72
- - -
1.47 X 103
2.48 X 10-1

- - -
7.28 X 10
1.21 X 103
3.40 X 102
3.41 X 102
1.21 X 104
8.74 X 103
4.85 X 103
1.21 X 102
5.22 X 102
3.66 X 10-1
8.53
1.46 X 105
6.55 X 103
1.21 X 103
1.21 X 103
4.85 X 104
1.28 X 10
4.92 X 10
4.85 X 104
2.33
2.43 X 103
- - -
4.49 X 10
2.33 X 102
2.43 X 104
2.33 X 102
1.70 X 103
2.43 X 105
1.35

1.03 X 102
2.20
1.32 X 102
3.67 X 10
3.55
1.32 X 103
1.03 X 103
2.50 X 102
1.47 X 10
1.49 X 10
1.04 X 10-2
6.13 X 10-1
1.54 X 104
8.07 X 102
1.21 X 103
1.21 X 103
7.34 X 103
3.59 X 10-1
3.59 X 10
2.94 X 103
6.51 X 10-2
1.47 X 103
4.24 X 103
1.30
1.23 X 10
2.57 X 103
6.72
1.70 X 103
1.47 X 103
2.48 X 10-1

1.50 X 10-2
9.73 X 10-3
1.62 X 10-1
5.00 X 10-2
1.23 X 10-2
2.00
1.30
6.49 X 10-1
2.00 X 10-2
2.00 X 10-2
1.32 X 10-5
1.00 X 10-3
2.00 X 10
1.00
1.62 X 10-1
2.00 X 10-1
6.49
4.61 X 10-4
5.00 X 10-3
6.49
3.00 X 10-3
3.24 X 10-1
2.00 X 10-1
5.00 X 10-3
8.38 X 10-3
4.00
8.38 X 10-3
3.00 X 10-1
4.00 X 10
2.00 X 10-3

1.53 X 106
1.44 X 106
1.64 X 106
1.64 X 106
- - -

5.14 X 104
5.14 X 104
5.14 X 104
5.14 X 104
- - -

4.85 X 105
4.85 X 105
4.85 X 105
4.85 X 105
7.28 X 104

5.14 X 104
5.14 X 104
5.14 X 104
5.14 X 104
7.28 X 104

6.49 X 10
6.49 X 10
6.49 X 10
6.49 X 10
1.00 X 10

5.2


25 (.. 2547) 20 (.. 2543)

CAS
Number
7440-38-2

71-43-2

50-32-8
7440-43-9

56-23-5

57-74-9
18540-29-9

57-12-5

50-29-3
107-06-2
156-59-2
156-60-5

60-57-1
100-41-4

76-44-8
1024-57-3

58-89-9
7439-92-1
7439-97-6
7440-02-0

87-86-5
7782-49-2
100-42-5
127-18-4
108-88-3

79-00-5

79-01-6

75-01-4
1330-20-7
7439-96-5

75-35-4

75-09-2
74552-83-3
93616-39-8

94-75-7
7440-50-8
9029-97-4

(/)

(/)

(/)

(/)

Arsenic
Benzene
Benzo(a)pyrene
Cadmium
Carbon tetrachloride
Chlordane
Chromium (VI)
Cyanide
DDT
1,2-Dichloroethane
cis-1,2-Dichloroethylene
trans-1,2-Dichloroethylene
Dieldrin
Ethylbenzene
Heptachlor
Heptachlor epoxide
g-HCH (Lindane)
Lead
Mercury
Nickel
Pentachlorophenol
Selenium
Styrene
Tetrachloroethylene
Toluene
1,1,2-Trichloroethane
Trichloroethylene
Vinyl chloride (chloroethene)
Xylene (Total)
Manganese
1,1-Dichloroethylene
Dichloromethane
1,1,1-Trichloroethane
Atrazine
2,4-D
Copper
Zinc

5.7
2.7
0.009
6.1
0.06
3.9
5.0
4,850
0.2
0.8
257
514
0.005
7,340
0.02
0.008
0.06
103
2.2
250
0.6
1,210
7,340
36.0
2,940
1.3
12
0.25
51,400
2.2
0.4
3.5
21.0
4.0
5.0
-
-

27
15
2.9
810
5.3
110
640
35
120
7.6
150
210
1.5
230
5.5
2.7
29
750
610
41,000
110
10,000
1,700
190
520
19
61
8.3
210
32,000
1.2
210
1,400
110
12,000
-
-

0.05
0.005
0.009
0.03
0.005
0.002
0.2
0.7
0.0003
0.005
0.3
0.7
0.00001
3.2
0.0004
0.0002
0.0002
0.02
0.01
0.6
0.001
0.2
6.5
0.005
6.5
0.005
0.008
0.002
65.0
0.01
0.01
0.01
0.2
0.01
0.1
10.0
10.0

0.00001
0.005
0.0002
0.000003
0.005
0.0002
0.00005
0.2
0.002
0.005
0.07
0.1
0.00003
0.7
0.0004
0.0002
0.0002
0.00001
0.000001
0.00002
0.001
0.00001
0.1
0.005
1
0.005
0.005
0.002
10.0
0.5
7.0
5.0
200
3
30
1.0
5.0

47

48


. 2549. .


2 2549 ...


3 . , 30 2549,


.
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51

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