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shamhu@varichem.co.

zw

Definition
glycogen breakdown to glucose in response to

hypoglycaemia through negative feed back mechanisms of the sympathetic nervous system

shamhu@varichem.co.zw

Effects.
Prevents hypoglycemia
Powerful system to degrade glycogen Increases glucose synthesis from amino acids

Increases with exercise independent of blood glucose


Exerts effects through cAMP second messenger

system

shamhu@varichem.co.zw

Glucagon Control
Exercise Amino acids

Adipose

Triglyceride breakdown Triglyceride storage

Fatty acids

Pancreas
Alpha cells Epinephrine (stress)

Liver

Glycogen breakdown Glucose synthesis Glucose release

Blood glucose

Brain
No effect Feedback

shamhu@varichem.co.zw

shamhu@varichem.co.zw

shamhu@varichem.co.zw

Thank you.

shamhu@varichem.co.zw

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