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Curriculum Vitae Provide a brief CV showing education and research training, including any prizes or awards: (no more than one page)

Education: MSc in Biotechnology; CGPA 3.93 out of 4; Academic Standing: Highest Distinction

Research Experiences: 1. MS Fellow, Bangladesh Academy of Sciences - United States Department of Agricultural funded project for salinity tolerant tomato production employing transgenic approach. Accomplishment: MS thesis entitled Cloning of an antiporter gene from PCR amplicons into a recombination competent vector containing a constitutive prompter (CaMV35S) Duration: November 2010 October 2011 2. Research Associate, Plant Biotechnology Lab, Department of MNS, BRAC University, Dhaka, Bangladesh Responsibilities: Biological data analysis applying novel and existed bioinformatics tools; Agrobacterium mediated Transformation, Cloning; Lab management, Presentation on the work progress, Guide on the other MS students MS thesis work, Lab procurements etc. Duration: November 2011 to till to date

Training and Conferences: 1. 5th International Conference on Microbiology of Food, Health and Environment: Problems and Prospect in Developing Countries, Organized by Microbiology Department, University of Dhaka. 2. Five day long workshop in Immunology and High Throughput Techniques at Immunology Lab, ICDDR,B, Dhaka 3. Training Program in General Laboratory Safety, Safe Laboratory Design, Chemical Safety, Waste Management and Bio-safety, ICDDR,B, Dhaka 4. Conference of the Bangladesh Society for Biochemistry and Molecular Biology, 2012 Organized by: Bangladesh Society for Biochemistry and Molecular Biology

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5. 3rd National Congress on Biotechnology and its prospect, Organized by Young Biotechnologists Bangladesh. 6. Novartis Biocamp-2011 7. Participation as a surveyor in a base line survey on Situation analysis of Medical Biotechnology in Bangladesh. Directed by Centre for Medical Biotechnology, Govt. of Bangladesh. Awards and Achievements: 1. Performance based tuition fees waiver at BRAC University during MS 2. Full tuition Fees Waiver at Higher Secondary Level from A.M.R. College 3. Board Stipend after Secondary School Certificate Examination 4. Junior Scholarship 5. Primary Scholarship

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List of Publications in International Journals*

Publications: 1. Amitav Das, Alak K Dutta, S. Razzaque, B.Saha, Partha S. Gope (2011), Analgesic and Antidiarrheal Properties of the Latex of Calotropis Procera, International Journal of Pharmaceutical & Biological Archives, Page 521-525 2. Md.Abu shoyeb, Samsad Razzaque, Aubhishek Zaman, Mohammed Rahamatulla (2012), Assaying Antihyperglycemic Effects of Crude Methanol Extract of Amaranthus spinosus in Swiss Albino Mice, International Journal of Research in Phytochemistry and Pharmacology. Accepted 3. Abstract Publication on Designing an in-silico protein-protein interaction profile and gene regulatory network for Kaposis Sarcoma-associated Harpes Virus in an ICGEB, New Delhi Symposium on Anti-virals for the Developing Worlds. 4. Samsad Razzaque, Naiyyum Choudhury (2012), Techniques of Proteomics and its Application in Health and Disease Control, Bangladesh journal of Medical Sciences. Submitted 5. Abstract Publication on Proteomics in Health and Disease Control, Published in 5th International Conference on Microbiology of Food, Health and Environment: Problems and Prospect in Developing Countries, Organized by the Department of Microbiology, University of Dhaka. 6. Abstract publication on Molecular cloning of the Na+/H+ exchanger gene from Arabidopsis thaliana and Oryza sativa for tomato (Lycopersicon esculentum Miller) transformation and conferring salt tolerance in Biochemistry and Molecular Biology Conference, Rajshahi University, Bangladesh. 7. Manzur E- Mohsina Ferdous, Samsad Razzaque, Debashis Chakrobarty, Zeba Islam Seraj, Aparna Islam (2012), Cloning of Na+ /H+ antiporter gene and establishment of in vitro regeneration protocol in tomato (Lycopersicon esculentum Miller) to develop salinity stress tolerant variety, International Conference on Biotechnology and Food Engineering. Accepted 8. Taslima Haque, Samsad Razzaque, Zeba Islam Seraj (2012) In silico prediction of MicroRNA and their targets in Plasmodium Falciperum, Manuscript in Progress. 9. Samsad Razzaque, Cloning of an Antiporter gene from PCR amplicons into a recombination competent vector containing a constitutive promoter. MS thesis. BRAC University online library. Popular Science article for GNOBB (www.gnobb.org) 1. Evidence Adduced for Lateral Gene transfer in Eukaryotes, published online at GNOBB website on March 6, 2012 2. Cross kingdom transfer of functionally active miRNAs, published online at GNOBB website on March 22nd , 2012 3. Novel Mechanism of Influenza Virus against Human Antiviral Response, published online at GNOBB website on March 31st , 2012
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4. The sequencing of tomato genome: Hopes and Prospects, published online at GNOBB website on June 13 , 2012 5. Comparative Epigenomics - A classified approach to functionally annotate genomes, published online at GNOBB website on June 17 , 2012 6. Influenza virus: Transmission possibility between mammals, published online at GNOBB on June 27, 2012 7. Genome sequencing of bonobo: A comparative study on evolutionary relationship, published online at GNOBB on July 1, 2012 8. A computational model proposed to elucidate mutation scenario, published online at GNOBB on July 4, 2012 9. Impact of the mechanical pressure during cell division, published online at GNOBB on July 8, 2012 10. Salt cress genome provides new clues for adaptive evolution, published online at GNOBB on July 17, 2012 11. A Unique Computer Model Proposed for Mycoplasma genitalium, published online at GNOBB on July 23, 2012

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12. Abstract Indicate below the abstract that is submitted by you for presentation at the YSP and the FAOBMB Congress in Bangkok (include all authors, affiliation(s) and the text of the abstract)

Designing an In-silico proteinprotein interaction profile and Gene regulatory network for Kaposis sarcoma associated Herpes Virus

Aubhishek Zaman1, 4, Md. Habibur Rahaman1, 3, 4, Samsad Razzaque2, 3, 4

1. Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka1000, Bangladesh 2. Biotechnology Program, Department of MNS, BRAC University, Dhaka-1212, Bangladesh 3. Plant Biotechnology Lab, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka- 1000, Bangladesh 4. Contributed equally ABSTRACT:

Herpes Simplex Virus 8 (HSV8) is the causative agent for a cancerous tumor of connective tissue which is widely known as Kaposi's sarcoma. The cancer involves skin, lungs, gastrointestinal tract, and other organs and is often associated with AIDS. Inspired by an urge to design an effective drug against the virus through a systems approach, here we have tried to establish a regulatory network involving key host virus interactions. The network comprises uncharacterized ORFs of the virus as well as interacting host proteins. We collected sequence information from public databases and structurally characterized the protein products of the ORFs using online servers- PSIPRED, CPHmodels- 3.0 and I-TASSER. For functional analysis of the individual ORFs MotifFinder tool was used. Consequently partner profile for each ORFs was predicted using String 9.0. Data mining tool Ali Baba further helped us to integrate predicted networks and interactions. SAGE and Microarray data, signifying gene expression temporally, was useful to quantify association between the nodes.To compare our interaction topology with standard known ones, PathBLAST and NetworkBLAST were used. Moreover, MicroRNAs were predicted applying online tools and databases like RNAFold, MatureBayes, Mipred etc. Targets of the predicted MicroRNAs were also analyzed applying Miranda in the host and Human. Finally, with the help of Cytoskape and CentiBin bioinformatic platform the results were represented as networks. Our study establishes both a protein-protein interaction profile and a gene regulatory network. The topology of the protein-protein interaction profile helped us to predict a pathway whereas the gene regulatory network revealed binary relationships among the genes. This study needs to be further investigated and validated in vitro. The network we propose here can be used to design antivirals in the future against HSV8 by targeting the network.

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Personal Statement Indicate briefly here your Research Interests and Career Goals, why you are interested to participate in the YSP Program (including what you will bring to the YSP and what you hope to gain from it): (no more than one page)

Science has always been a passion to me since high school days. A basic and fundamental difference with the glimpse of epigenomics, the whole structure of life is a mystery to me. I started finding the answer through the available source, and then I decided to pursue my Undergrad in Zoology and then did my MS in Biotechnology with a thesis in Molecular Biology. I am still on my way searching the answer and the beauty of nature in creating such ways to transform the characters into a multi tasking approach still amaze me.

To build up a greater or significant community in science it is very important to establish an interacting environment to do the sharing and thoughts. I believe interacting with researchers around the globe will surely enhance my ideas and thoughts towards science more precisely. This opportunity will apparently help me in understanding the trends and challenges in the expansion of different applied and classical biological sectors like Cell biology, Genetics, Human biology, Microbiology, and newly developed biological techniques. This knowledge will not only allow me in better understanding biological and natural principles but will also allow me to learn all the breakthrough of new discoveries and the trends & challenges in the applied biology sector. This conference will also give a chance to interact with key experts and leaders from all around the world. Therefore, I believe attending in this conference of FAOBMB will provide the necessary background for me to be to anticipate and to react to ever-changing environments using the experience of the experts.

In this regard I would like to mention that during my undergraduate and graduate studies, emphasis was given entirely to understand the fundamental biological principles that govern modern day of Biological advancements. I also learned about other topics such as bio-safety, laboratory management and recombinant DNA technology. I am highly interested to deal with novel Biological techniques to follow up the regulation and corresponding genetic pathways that lead to specific functional characteristics and want to find out specific regulatory promoters and specific signaling pathways from both the indoor and outdoor influences. My aim in life is to explore and to see the inner beauties of genetic mechanisms through all possible ways. I am very much interested in Molecular Biology, Cell Biology, Drug Designing, Neural Biochemistry and Bioinformatics. Being a part of the program, I will get a more expand area on my thoughts and beliefs. I would really love to be a part of the event and waiting like to see a horizon through it.

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Attachments:

Letters of recommendation from two referees.

Submission methods: You can apply in either of two ways:

by sending an email with scanned attachments to the Chair of the FAOBMB Fellowship Committee, Prof. Piamsook Pongsawasdi: piamsook.p@chula.ac.th or piamsook.p@gmail.com

This is the preferred method. If using this method, please assemble the Application Form and the Attachments into a single PDF file.

by sending a hard copy of the application form and supporting documents to: Professor Piamsook Pongsawasdi, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

Closing Date: Applications must be received by 31 July, 2012 (Bangkok time, GMT + 7 Hours). Applicants will be notified by email of the decision of the Committee by no later than 15 September, 2012.

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BRAC UNIVERSITY
To whom it may concern
It is a great pleasure to spend a moment writing this letter of recommendation for Mr. Samsad Razzaque whom I have known for more than 2 years as he has taken the following courses which I teach:, Environmental Biotechnology, Fermentation and Industrial Biotechnology and Enzymology. I had the opportunity to work with Samsad in most of the facultys activities. He showed true leadership characters when working with people, utilizing diplomatic approach. As a result of his manners, his friends always supported him. In class, Samsad showed his intelligence, creativeness, and high responsibility attitude. His grade is the indicator of intelligent and academic integrity. As per his performance records, he can be on the overall in the top of the class. He is intelligent, inquisitive and yearns to gain an indepth knowledge. With his determination and hard work I have no doubt that he will succeed in all his endeavors. With the combination of his leadership character, knowledge and intelligence, talent, and much contribution to fellow students and faculty activities, he was one of my outstanding students. I strongly recommend him with pride and confidence without any reservations and wish him further success. Sincerely,

Dr. Naiyyum Choudhury, Professor Coordinator, Biotechnology Program Department of Mathematics and Natural sciences BRAC University 66 Mohakhali, Dhaka-1212 Bangladesh Mobile No +88-01712-680-879 E-mail: naiyyum@gmail.com Website: http://www.bas.org.bd/fellowship/list-of-fellows-/userprofile/naiyyum.html

66 Mohakhali, Dhaka-1212, Bangladesh Tel: +880 2 882 4051 Fax +880 2 8810383 e-mail: info@bracuniversity.ac.bd www.bracuniversity.ac.bd

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BRAC UNIVERSITY
To Whom It May Concern
I know Mr. Samsad Razzaque since January 2010 in the capacity of his course teacher, guide for his research programme and PI of the project he is working at the moment. His performance was outstanding as a student and also as a researcher. Mr. Razzaque has kin aptitude for science specially in the field of Molecular Biology and Bioinformatics and have an open mind to learn more and more. He actually believes that there is no end of learning. Mr. Razzaque possesses good general knowledge and analyzing capacity related to research issues with productiveness. As his project supervisor, I had the occasion to evaluate his working attitude and trouble shooting of any research hurdle which really amazed me. His presentation skill is equally appreciable. This I witnessed when he offered a seminar on his project Cloning of an Antiporter Gene from PCR amplicons into a recombination competent vector containing a constitutive promoter. His mode of presentation using the audio visual aid was really impressive. Mr. Razzaque has the aptitude, thorough knowledge and management skills in carrying out any given assignment with perfection and within time. I found him excellent as group worker and his potential as a group leader is really highly recommendable. A candidate with good reading, writing and communication skills, I trust Mr. Razzaque will fulfill the academic expectations of your esteemed faculty. I am sure that with the guidance and expertise of your renowned graduate school, he will be able to develop independent school of thought and judgment towards the life science research. He has maintained a consistent academic record of CGPA 3.93 out of 4.00 and in my opinion I rank him among the top 5% of the students I have come across. He is a candidate with reading and writing skills and I am sure that he will fulfill the academic expectations of your University. His conduct and character are very good and I very strongly recommend him for admission in your University. In one word I am proud to be his teacher and guide. I wish him all success in his future academic feat.

Sincerely, Aparna Islam, PhD Editor, Journal of Plant Tissue Culture & Biotechnology (PTC&B) Website of PTC&B: http://www.baptcb.org/ Assistant Professor, Biotechnology Program, Department of Mathematics and Natural Sciences, BRAC University, Dhaka-1212, BD Ph: 0088-8824051-4, extn 4153 Ph: 00-88-02-8954487; 00-88-01817114304 (m), Skype:aparnai20
66 Mohakhali, Dhaka-1212, Bangladesh Tel: +880 2 882 4051 Fax +880 2 8810383 e-mail: info@bracuniversity.ac.bd www.bracuniversity.ac.bd

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