William C. Menninger Memorial Award Lecture: PTSD and Other Trauma-Related Disorders
AL 003
Faculty
Robert J. Ursano, MD Disclosure: Has no relationship with any proprietary entity producing health care goods or services consumed by or used on patients. Clinical questions to be addressed: 1.What psychiatric and behavioral disorders follow traumatic events, disasters, and war? 2.What are predictors of these disorders? Who is at risk? 3.How to treat and care for post traumatic stress disorder and behavioral problems after the trauma.
Natural
The Past One type of symptomatic behavior associated with depressions, either neurotic or psychotic in type, is suicide. Between July, 1940, and June 1946, there were 2,214 suicides in the Army, 300 of which occurred among officers.1 .these figures represent g g p a sharp drop during the war period from the peacetime suicide rate in the Army. 2 There was also a sharp drop in the number of suicides in the Army in World War
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Army News Service, http://www.army.mil/-news/2009/03/31/19022-army-vicechief-addresses-suicide-rate-across-army/, March 31, 2009 Jelinek, P., Army suicide rates at record high. Associated Press, 5/30/2008
Suicide Ideation
WHO Study: 108,664 respondents from 21 countries
A wide range of mental disorders increased the odds of experiencing suicide ideation ideation.
Survival Bivariate models : number of temporally primary lifetime DSM-IV/CIDI disorders and the subsequent first occurrence of a suicide attempt Response variable: lifetime attempt among total sample (n = 5692)
Exactly 1 disorder Exactly 2 disorders E Exactly 3 di d tl disorders Exactly 4 disorders Exactly 5 disorders
3.7 (2.84.9)* 6.8 (4.89.7)* 12 1 (7 8 18 6)* 12.1 (7.818.6)* 16.4 (11.722.9)* 12.8 (7.422.1)*
U.S. Army Child Neglect Rates Age 1-2 year olds, 1989-2004
7 6 Rate per 1,000 5 4 3 2 1 0
1 to 2 Years
19 89 19 90 19 91 19 92 19 93 19 94 19 95 19 96 19 97 19 98 19 99 20 00 20 01 20 02 20 03 20 04
Years
McCarroll J et al CSTS USU, 2005
Engel: Green et al. Ecology of medical care revisited. NEJM 2001; 344(26):2021-5
http://commonfund.nih.gov/epigenomics/
TBI
Headache Nausea vomiting Dizziness
Anxiety
Jaffee et al DVBIC 2008; Chen et al Dep TBI Arch Gen Psych 2008
100 95% 90
7% contact within year of PTSD onset and 12-year median delay to first treatment contact
94% 90% 88% 86%
80
70
65%
Panic Disorder Dysthymic Disorder Bipolar Disorder Major Depression GAD PTSD
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GAD, generalized anxiety disorder. Wang PS, et al. Arch Gen Psychiatry. 2005;62:603-613.
Controversies
or Please answer
1) Debriefing 2) EMDR? 3) CBT? 4) Benzodiazapines? 5) SSRIs? 6) We can prevent PTSD? 7) We should intervene early to prevent PTSD? 8) Psychodynamic Rx is irrelevent to PTSD? ***Prazosin, Virtual Real, DcycloS (alpha adrenergic antagonist)
CSTS Books
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