• Hemodynamics
o Compliance - ΔV/ΔP
o Poisseuille's
• 4th power law
• Q = ΔPπr^4/8ηl
η - viscosity
l - length
• Thus even small constriction / dilation can have large influence on blood flow
• Anemia - dec viscosity - inc blood flow
o Autoregulation - Tissues does it itself
• Blood flow is extremely constant over a range of pressure (~60-160)
• Diameter dec to prevent pressure from having negative effects on important organs
• Note
Flow = P1-p2 (Part - Pven)
Compliance = Pin - Pout
• EKG's
o Fast response- contractile cells – see lectura for pic
o
• Phase 0 - Na+
• 1-
• 2 - Ca+ : L-type
• 3-K-+
• RMp - mostly K+ diffusion
o Slow response - SA node, AV node
• 0 - Ca+ T-type
• 3- K+
• 4 - 3 parts
A - slow Na+
B - ca++ leak
C - K+ close - MOST IMPORT
o Normal vector
o Process
• SA - AV = atrial depol
• Stalls at AV node
• Av -> purkinje -> vent = vent depol
o Normal EKG