Corpus, Carmencita L.

Generic Name Losartan potassium Brand Name: Cozaa r Dosage/ Frequency Classification Angiotensin II receptor blocker (ARB), Antihypertensi ve Indication Treatment of hypertension, alone or in combination with other antihypertensi ve agents Treatment of diabetic neuropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension Contraindicati on Contraindicat ed with hypersensitivi ty to losartan, pregnancy (use during the second or third trimester can cause injury or even death to the fetus), lactation. Side effects Headache, dizziness, syncope, insomnia, Hypotension, Rash, urticaria, pruritus, alopecia, dry skin, Diarrhea, abdominal pain, nausea, constipation, dry mouth, URI symptoms, cough, sinus disorders, Cancer in preclinical studies, back pain, fever, gout, muscle weakness Nursing responsibilities Administer without regard to meals. Ensure that patient is not pregnant before beginning therapy, suggest the use of barrier birth control while using losartan; fetal injury and deaths have been reported. Find an alternative method of feeding the baby if given to a nursing mother. Depression of the reninangiotensin system in infants is potentially very dangerous. Alert surgeon and mark patient's chart with notice that losartan is being taken. The blockage of the reninangiotensin system following surgery can produce problems. Hypotension may be reversed with volume expansion. Monitor patient closely

Corpus, Carmencita L.
in any situation that may lead to a decrease in blood pressure secondary to reduction in fluid volume-excessive perspiration, dehydration, vomiting, diarrhea--excessive hypotension can occur.

Corpus, Carmencita L.

Generic Name Furosemide

Dosage/ Frequency PO: ADULTS, ELDERLY: Initially, 20-80 mg/dose; may increase by 20-40 mg/dose at 68 hour intervals. May titrate up to 600 mg/day in severe edematous state, CHILDREN: 1-6 mg/kg/day in divided doses q6-12 hours. IM/IV: ADULTS, ELDERLY: 2040 mg/dose; may repeat in 1-2 hours and increase by 20 mg/dose. CHILDREN: 1-2 mg/kg/dose q6-12 hours. NEONATES: 12 mg/kg/dose

Classification

Indication Treatment of edema associated with congestive heart failure, chronic renal failure, hepatic cirrhosis, and acute pulmonary edema. It is also used for treatment of hypertension, alone or in combination with other hypertensives . Can also be used for treatment of hypercalcemi a.

Contraindicati on Contraindicat ed with hypersensitivi ty to furosemide

Side effects

Increase in urinary frequency or volume Nausea Gastric upset with cramping Diarrhea or constipation Electrolyte disturbances Dizziness or light headedness Headache Blurred Vision Paresthesia Photosensitivity Rash Weakness Bladder spasm Restlessness Diaphoresis Flank or loin pain

Nursing responsibilities Give with food to avoid gastroinestinal upset, preferably with breakfast (to prevent nocturia).

If given IM, temporary pain at injection site may be noted. Check vital signs especially blood pressure for hypotension prior to administration. Assess baseline electrolyte, particularly check for low potassium. Assess edema, skin turgor, and mucous membranes for hydration status.

Corpus, Carmencita L.
q12-24 hours. IV infusion: ADUL TS, ELDERLY: Bolus of 0.1 mg/kg, then 0.1 mg/kg/hour; may double q2hours. Maximum: 0.4 mg/kg/hour. CHILDREN: 0.05 mg/kg/hour, titrate to desired effect.

Assess muscle strength and mental status. Obtain baseline weight. Initiate Input and Output monitoring. Note extent of diuresis.

Corpus, Carmencita L.

Generic Name Amlodipine

Dosage/ Frequency Alert: Dosage should be titrated over 714 days. Hypertension PO: ADULTS: Initially 5 mg/day as single dose. Maximum : 10 mg per day. PO: SMALLFRAME, FRAGILE, ELDERLY: Initially 2.5 mg/day as single dose. Angina (Chronic, Stable, or

Classification Calcium channel blocker, antihypertensive, and antianginal.

Indication Hypertension, chronic stable angina, and vasospastic angina. It may be used alone or with other antihypertensives or antianginals.

Contraindicati on Contraindicate d with hypersensitivi ty to Amlodipine

Side effects

Nursing responsibilities

Peripheral edema Headache Flushing Dizziness Palpitations Nausea Unusual tiredness or weakness Chest pain Bradycardia Orthostatic Hypotension

Assess baseline renal and liver function. Assess blood pressure. Assess apical pulse. Assess for peripheral edema behind medial malleolus. Assess skin for flushing. Question for headache and weakness. May be given without regards to food. Grapefruit juice may increase drug

Corpus, Carmencita L.
Vasospastic) PO: ADULTS: 520 mg. ELDERLY, HEPATIC, INSUFFICIENCY: 5 mg. Dosage in Liver Impairment PO: ADULTS, ELDERLY: Initially, 2.5 mg per day concentration.