QMU 4th WEEK Patho 23 mac 1) Death of group of hepatocyte in the middle of lobule Which type of necrosis refered

to the statement : A. Bridging necrosis B. Interface necrosis C. Lytic necrosis D. Single cell death answer = C 2) All are the cause of systemic viral infection , Except : A. Rubella virus B. Cytomegalovirus C. Yellow fever D. Herpes simplex virus type 2 Answer = D 3) Intrahepatic cause of portal hypertension is A. Bilharzial hepatic fibrosis B. Budd Chiari syndrome C. Right side heart failure d. Portal vein obstruction Answer = B 4) Jaundice appears in _________ phase of acute hepatitis. A. Incubation period B. Preicteric phase C. Icteric phase D. Convalescence Answer= C 5) All of this are biochemical changes of Acute viral hepatitis , Except : A. Elevation alkaline phosphate B. Prolong prothrombin time C. Elevation serus transaminase D. Conjugated hyperbilirubinemia Answer = A

Microbe 23 mac 1) family virus of hepatitis C : A. Heparnaviridae B. Flaviviridae C. Picornaviridae answer = B

2) Transmission of hepatitis B , Except : A. Fecal oral route B. Sexual transmission C. Breast feeding D. Needle stick injury Answer = A 3) All the following are true about Hepatitis B , Except : A. 90-95 % adults recover completely B. EM shown Spherical , filamentous, & Dane particle C. Prevention by Formalin Vaccine D. HBIG & vaccine is needed for Infant born to HBV positive mother Answer= C 4) Hepatitis D : A. Sexually transmitted B. Small circular RNA genome C. Can replicate itself and have gene code for envelope protein D. Incubation period is 2-12 weeks Answer = C 5) Why HCV RNA test is very helpful in Lab diagnosis: A. confirm the presence of active disease B. Diagnose infection in early seronegative phase C. diagnose infection in patient with poor serologic response D. All the above Answer = D

Patho 24 mac 1.The cause of hepatic encephalopathy is : a. Increase urea in the blood. b. Increase ammonia in the blood. c. Increase K in the blood. d. All the above. 2.Carrier state: a. Could occur with HBV,HCV and HEV b. An individual cannot transmit the virus during this period c. An individual does not manifest symptoms d. A & C 3.Rapidly progressing hepatic insufficiency with hepatic encephalopathy extends up to 3 months : a. Fulminant hepatic failure b. Acute hepatic failure c. Subfulminant hepatic failure d. None of the above 4.All of the following are clinical features of hepatic failure, except: a. Gynecomastia b. Increased tendency for blood clotting c. Respiratory failure d. Fetor hepaticus 5. which virus lead to fuliminant in case of pregnancy a. HBV b. HEV c. HDV d. HCV ANSWER: B,C,C,B,B Parasite 24 mac 1) Which of the following is the infective stage of Fachiola Hepatica A. Metacarcria B. Encysted metacacria C. Radiae D. Eggs

2) Which is the correct statement regarding Fasciola Hepatica : A. The testes faschiola hepatica are more than two B. Metacercaria distributed at normal sites are called Ectopic fasciolisis C. The lateral diverticulae of the intestinal caeca are highly branched and the medial ones pocket-like. D. The eggs are one the infective stage 3) The following are the clinical manifestations of the established infection stage , Except : A. Edema B. Fever C. Liver enlargement D. Acute epigastric pain

4) Which of the following is True : A. Halzoun is due to ingestion of cooked liver. B. True fuscioliasis is due to ingestion of raw liver C. False Fascioliasis is to be examined after 3 days ingestion of liver D. Ectopic fascioliasis is distributed at normal sites 5) The drug use to treat fasciola hepatica insfection A. Triclabendazote B. Erithromyocin C. Cephalosporine D. Tetracycline Patho 25 mac

1)those are the intrahepatic cause of portal hypertension except a- portal microcirculation disease b- Budd chiari syndrome c- diffuse granulomatous disease d- cirrhosis

2) what is the manifestation of portal hypertension? a. decrease hydrostatic P within intestinal capillaries b. dehydration c. caput medusae D. haemoptysis of blood due to esophageal varices

3) Cavernous hamengioma is benign. which is correct? a- rupture lead to intra abdominal hamorrhage b- located outside liver capsule c- well circum capsulated benign llesion d- might be mistaken for hepatocellular carcinoma

4) which is true about hepatocellular carcinoma a- gain of weight due to inability to secrete bile which emusify fat b- microscopic type of conventional type and fibrocircular carcinoma c- 90% patients have elevated alpha 1 antitrypsin activity d- hard mass due to carcinoma type tumor

5) metastatic tumor: a- elevated alphafetoprotein b- less malignant than hepatocellular carcinoma as it does not arise primarily in the liver c- usual primary sites include the colon, lungs, pancreas d- liver enlarged with multiple nodules show central necrosis

Parasite 25 mac

1) Eggs of schistosoma mansoni . All are correct Except: A. oval B. Immature miracidium C. lateral spine D. 150 x 65 micro m size 2) Egg S. mansoni escape to fall in the lumen of A. Miracidial antigens B. Egg shell spine C. Contraction intestinal muscle D. All of the above

3) Infective stage of S. Mansoni A. cercariae B. Metacercariae C. Sporocyts D. Miracdia 4) Stage of invansion and maturation includes , Except A. cercarial penetration B. Schistosoma migration C. maturation D. Egg extrusion 5) Treatment of schistosoma mansoni : A. Vermox B. Egaten C. Praziquentel D. Antiver

PHYSIOLOGY(26 MAC 2013) 1. Below are types of food digested by pancreatic secretion, EXCEPT A. Fats B. Vitamin C C. Protein D. Carbohydrates Answer : B 2. Substances that neutralize the gastric acid chyme in duodenum are i.sodium bicarbonate ii.bile iii.sodium phosphate iv.intestinal juice A.ii, iii B.iii,iv C.i,ii,iv D. I,iv Answer : C 3. Which one is type of proteolytic enzyme A. Cholesterol esterase B. Proelastase C. Pancreatic lipase D. Pancreatic amylase Answer : B 4. Which is TRUE regarding the effects of loss of pancreatic juice ? A. No digestion occur B. Metabolic alkalosis C. Steatorrhea D. Dehydration Answer : D 5. Choose the CORRECT types under the hormonal regulation of pancreatic secretion i.vasoactive intestinal peptide(VIP) ii.gastric juice iii.CCK iv.secretin A.i, iv B.i, iii, iv C.ii, iv D.i, ii, iii, iv Answer : B

6. Choose the TRUE statement regarding extra-pancreatic acting on CCK A. High intestinal movements B. Regulation of food intake C. Contraction of pyloric sphincter D. All of the above Answer : D
Anatomy 26 mac

1. The following are the peritoneal recesses except a. Superior duodenal recess b. Supra duodenal recess c. Inferior duodenal recess d. Paradudenal recess e. Retroduodenal recess 2. The following are branch of coeliac trunk except a. Left gastric artery b. Splenic artery c. Hepatic artery d. Superior mesenteric artery 3. Which of the following is false regarding the relations of 2nd part of duodenum a. Anterior : right lobe of the liver b. Posterior : hilum of the right kidney c. Lateral : Hepatic flexure of the large intestine d. Medial : head of pancreas, bile duct, and gastro-duodenal duct 4. 2nd part of duodenum covered by peritoneum anteriorly and posteriorly a. True b. False

5. Superior pancreatico-duodenal artery supply the midgut of the duodenum a. True b. False

ANATOMY 27 MAC 1- all of the following are the structures crossed by the root of mesentery EXCEPT A : IVC B : left genito femoral nerve C : 3rd part of deudenum D : abdominal aorta 2- Arterial arcades are found in between 2 layer of mesentery A : true B : false 3- what is the arterial supply of posterial wall of the caecum ? A : posterior coecal artery B : right colic artery C : colic branch D : middle colic artery 4- superior mesentric artery is the artery of .......... A : foregut B: midgut C : hindgut 5- the descending branch of the right colic artery runs down to anastomose with ............. A : middle colic artery B : anterior coecal artery C : colic branch D : posterior coecal artery

Histology 27 mac 1) Which of the following are the modification of intestinal lumen? I. Permanent folds that mostly developed at the jejunum II. Numerous villi that is finger-like and leaf-like III. Closely packed mucuous neck cell IV. Microvilli covering each of the epithelial cell A. B. C. D. 2) A. B. C. D. I,II II,III I,II,IV I,III,IV Choose the correct pair. Intestinal epithelium lined by simple columnar cells with surface mucuous cells Central core of villus-rich in capillary loops, lacteal and few striated muscles Maximum absorption-jejunum>duodenum>ileum No of goblet cells-duodenum>jejunum>ileum

3) A. B. C. D.

Which of the following is False regarding lamina propria of intestinal mucosa? Its occupied by intestinal glands Contains large number of lymphocytes,macrophages,mast cells and plasma cells The appearance of Payer's patches at the ileum It occupies spaces between the crypts of Lieberkuhn

4) A. B. C. D. 5) A. B. C. D.

All of the following are the cell of the intestinal villi,EXCEPT. Absorptive columnar cells Goblet cells Paneth cell M-cell Choose the CORRECT pair Goblet cells-protects the epithelium from the abrasion M-cells-secrete lysozyme for immunological function Brunner's gland-abundant at the jejunum Absorptive columnar cell-resemble zymogen cells in small intestine

Answers: C,D,C,C,A Anatomy 28 mac 1. Presence of the following are the main differences between small and large intestine except: a. teniae coli b. microvilli c. sacculations d. appendices epiploicae

2. Which of the following positions of the appendix is true? a) Retrocecal (56%) b) Pelvic (20%) c) Subcecal (9%) d) Pre or post ileal (2%)

3. Which of the following is the arterial supply for pelvic (sigmoid) colon? a) A branch of ileocolic artery b) A branch from hepatic artery proper c) A branch from superior mesenteric artery d) Branches from inferior mesenteric artery

4. Which of the following is a content of transverse mesocolon? a) Superior mesenteric artery b) Middle colic artery c) Inferior mesenteric artery d) Appendicular artery 5. Transverse mesocolon is suspended from posterior abdominal wall by a) Greater omentum b) Flciform ligament c) Transverse mesocolon d) Mesentery Phisiology 28 mac 1. Brunners glands secretion is stimulated by all of the below EXCEPT A. Gastrin hormone B. Secretin hormone C. Vagal stimulation D. Contact of acidic chime with duodenal hormone Answer: A 2. Local nerve plexuses control the secretion of A. Brunners gland B. Goblet cells C. Mucous cells of intestinal gland D. Parietal cells Answer: C 3. Final digestion in intestine occurs in A. Intestinal lumen B. Brush border C. Cytoplasm of mucosal cells D. All of the above Answer; D 4. Enzyme responsible for trypsinogen activation is A. Trypsin B. Enterokinase C. Endopeptidase D. B and C Answer: B

5. The following hormone stimulate intestinal secretion A. CCK B. Secretin C. All of the above D. None of the above Answer: C