Right sided heart Hepatotoxic drugs Post hepatic/ post necrotic cirrhosis failure Excessive alcohol ingestion 1 biliary cirrhosis 2ndary biliary Chemical toxins Viral cirrhosis Hepa a virus infection Hepatitis B virus & hepatitis c virus Destructive metabolites Intrahepatic obstruction Extrahepatic Mild acute obstruction injury Continued or repeated Exaggerated Cell Fat Massive liver infection detoxification protein accumulation Blockage of bile necrosis in hepatocytes excretion Accumulation of Liver Chronic regeneration persistent Chronic active Inflammato bile in the hepatitis hepatitis ry cell hepatomegaly steatosis Autoimmune liver infiltration cell destruction Formation of Recovery stasis
Bile duct Decrease bile in the
Liver parynchymal Functional obstruction intestine Fibrosis stimulation Failure to destruction hepetocytes Death conjugate bilirubin Cholestatic Light colored feces Foci of regeneration jaundice Fibrous repair tissue Hyperbilirubinemia formed Scarring Bile salts Decreased bile salts Fibrosis Macro µ nodules formation Hepatocellular accumulate in in the liver jaundice the blood Diminished fat Liver cirrhosis Steatorrhea emulsification and Bile salts carries absorption Impaired Faulty urea Faulty protein Faulty Hormone Vascular Increase arterial Hepatorenal into tissues detoxification synthesis synthesis inactivation compression loading syndrome activity Increase gastrin in the Decreased vit. K Weight loss blood Pruritus absorption Increase Hypoalbuminemia Increase Increase resistance Increase flow Destruction of Toxin ammonia circulating of blood flow through hepatic live exaggeration in the Excessive stimulation through the liver vasoconstrictor Decrease clotting General of stomach parietal artery weakness Tissue exposure to factor synthesis cells Increase Hepatic estrogen Decrease blood Increase blood Increase susceptibility encephalopathy Oversecretion of acid flow to hepatic volume in sinusoid vasoconstrictor Clotting defects to infection veins and veins in circulation Gynecomastia Palmar erythem Ulcer formation DIC Agitation, Asterixis a Portal Congestion Interference in Kidney lethargy & (liver Flap) congestion kidney blood damage stupor Increase pressure in capillary Portal hypertension flow Coma beds Diversion of blood to Splenomegaly Hepatic shunting collateral channel Increase capillary Decrease venous return permeability Decrease leukopenia Hypersplenism thrombocytopenia Blood bypasses colloidal Fluid shift to extravascular Decrease BP the liver osmotic pressure compartment Susceptibility Excessive RBC Anemia Release of renin to infection lysis Increase portal flow By: Romeo Q. Rivera Jr. 09282434418 Ascites Hemoglobin release Engorgement Reference: Joyce Black: Medical-Surgical dyspnea Conversion of angiotensin 1 to angiotensin 2 & to angiotensin 3 Nursing Increase bilirubin Carol Porth: Pathophysiology,High vascular pressure Concepts Esophageal varices Hemorrhoids formation Abdominal vessel congestion of Altered Health States Secretion of Vasoconstriction aldosterone Lemone & Burke: Medical-Surgical Organisms gain access Hemolytic to peritoneal cavity Increase BP jaundice Protrusion in Caput esophageal lumen medusae Na & H2O retention Rapid proliferation Blood in stool Edema Hematemesis Erosion, rupture