Omega-3 Research Spotlight June 2007, Vol 1

the benefits of fish oil

Omega-3 Fatty Acids linked
to maintaining overall “By properly supplementing a healthy
Good Health* diet with Omega-3 fish oils, one
can powerfully support the optimal
The positive benefits of fish consumption functioning of the heart, brain,
continues to be validated by researchers and
scientists worldwide.  While fish serves as a bones, joints, skin and just about
great source of high quality protein, there every cell in the body.”*
are also numerous positive health supporting Dr. Irfan Qureshi
benefits.  Fish is a tremendous source of
healthy fats commonly known as Omega-
3 Fatty Acids. Studies conducted over the High levels of DHA and EPA
last decade continue to demonstrate the support cardiovascular
importance of consuming adequate amounts
of Omega-3 Fats. It is clear, these “good
health* 
fats” are a major contributor to sustaining
overall good health. Most importantly, these High levels of DHA/EPA in heart tissue
fats are a key factor in supporting optimal mirrors the concentration found in red
cardiovascular health. They also help blood cells. Those with the highest levels
maintain the proper function of our of DHA/EPA in the blood tend to have
brain, joints, skin, and each and every cell healthier cardiovascular function than those
throughout our body.* with lower levels. One such study followed
94 healthy men, without any evidence of
prior cardiovascular disease, for a period of
Healthier cardiovascular up to 17 years.  Baseline measurements of
function the fatty acid composition of the blood were
taken at the beginning of the trial. The trial
The relationship between cardiovascular
health and Omega-3 Fatty Acids
has been researched extensively. DHA
(Docosahexaenoic Acid) and EPA
(Eicosapentaenoic Acid), both powerful
Omega-3 Acids from fish oil, are also found
in high levels in heart tissue. (1) Studies
reveal a correlation between these high levels
of DHA/EPA in heart tissue and healthier
cardiovascular function.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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the benefits of fish oil
(continued)

analysis revealed that the men with the directly benefit the heart by promoting the
highest levels of Omega-3 Fatty Acids in maintenance of a normal, healthy heart
their blood were the least likely to suffer rhythm. (4) A healthy heart rhythm is
cardiovascular problems later in life. (2) essential for smooth, uninterrupted blood
flow and provides the basic foundation for
optimal cardiac function.

Omega-3 fish Oils Are

essential for Brain health*
The Benefits of fish consumption/Omega-
3 intake is confirmed in another trial that
studied women between the ages of 34 and Aside from being heart healthy, research
59. This study followed 79,839 healthy shows Omega-3 Fish Oils are also essential
women for up to 14 years to determine for brain health. DHA is by far the most
the relative risk of cardiovascular events predominant fatty acid in brain tissue,
compared to their dietary intake of Omega- accounting for upwards of 40% of the total
3 Fatty Acids.  The authors showed that weight of the human brain. (5) Therefore,
women who consumed fish at least 2 to 4 it should come as no surprise that Omega-
times per week had a 48% lower risk of 3 Fatty Acids play a major role in brain
cardiovascular problems than those who development, cognition, mood regulation
ate no fish, whereas those eating fish once and transmission of nerve signals.  A 4 year
weekly had a 22% lower risk. (3) study of men and women between the ages
Commenting on the reasons for these results, of 63-74 measured blood cell levels of fatty
the authors mention that Omega-3 Fatty acids. At the end of the 4-year period, the
Acids affect the production of the cascade men and women who had higher levels
of inflammatory prostaglandins and of Omega-3 Fats as a component of their
leukotrienes, thereby favoring the blood cell membranes were best able to
production of less inflammatory maintain normal cognitive function over
mediators.  This may allow this length of time.
for maintenance of the (6) Other studies have
pliability and elasticity of arteries, promoting found similar results. A
normal blood flow throughout the study conducted in The
circulatory system. Enhancing the health Netherlands looked at
of arteries naturally promotes healthy the link between fish
circulation, allowing for a healthy heart and fatty acid intake and
cardiovascular system.  Additional research cognitive function.  This
has confirmed that Omega-3 Oils can population based
study of over 1,600

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Purity Products 2
Omega-3 Fish Oil Powerfully Supports:

•  Heart/Cardiovascular Health* •  Healthy Triglyceride Levels*

•  Brain Health* •  Healthier Wrinkle Free Skin*
•  Memory and Concentration* •  Cellular Health*

subjects found that individuals with higher

fish and fish oil intake were on average
better able to maintain healthy memory
function and normal cognition. (7)

Omega-3 Fish oil and Positive

Mood

Another area where research on fish

oil is being conducted is that of mood structure and function of joint cartilage.  A
regulation and learning ability.  Studies show recent laboratory study conducted on human
that Omega-3 Fish Oils may have a profound and animal cartilage showed that when the
effect on promoting normal mood and affect. cartilage tissue was supplied with Omega-
One study examining the population of 3 Oils a noticeable protective effect was
different countries reveled a correlation seen. Degradation of the human and animal
between consumption of fish and enhanced cartilage in this lab experiment was
mood within the population. (8) A clinical noticeably slowed by the administration of
trial conducted at Harvard University omega-3 oils. (10) Given the research in
confirmed the ability of fish oil supplements this area, it is widely believed that omega-3
to enhance mood versus no effect seen in the oils have a positive impact on maintaining
placebo group. (9) These effects were seen healthy joint function.*
with high doses of fish oil.  Consumption
of fish and supplementation with fish oil in New research also
promoting optimal cognitive function is links Omega-3 oils to
certainly well indicated. Omega-3 fatty acids sustaining the health
play vastly important roles in maintaining and structure of our
excellent neural health. bones.* Studies show
that the makeup of
protect your bones and fats, consumed in our
joints* diets, has an impact
on the strength of our
bones.
Omega-3 Fatty Acids play a large role in
maintaining the health of yet another critical
part of the body, our bones and joints.
Studies have shown that Omega-3 Oils may
have a beneficial effect on maintaining the

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Purity Products 3
 Purity’s Advanced Omega-3 Formula provides Super Quality Omega-3 Fish Oil!
3 Super Concentrated 3 No Fish Aftertaste
3 Ultra-Purified 3 Pharmaceutical Grade
3 Up to 3X More Powerful 3 Easy to Swallow Lemon
Than Ordinary Fish OIl Flavored Soft Gels

Omega-3 Fish Oils support Maintain and enhance skin

Cellular health* health*

Omega-3 Oils derived from fish have the Omega-3 oils also help maintain and
potential to improve overall health through enhance the health of our skin.* The
their interactions with cells throughout incorporation of these fats into the epidermis
the body.*  Cell membranes are composed can result in improved look and feel of
of phospholipids, or fats, that can have skin tissue. (12) In vitro research on various
effects on membrane fluidity and cell-to-cell lines of skin cells shows that exposure to
communication.  Immune function, toxin EPA and DHA confers possible protection
removal and energy production all occur against some forms of ultraviolet radiation,
at the cellular level. The composition of maintaining the skin’s healthy resistance
phospholipid membranes is a direct against potentially harmful UV damage. (13)
reflection of the types of fats we eat.  Some Some trials have also shown that Omega-
components of these membranes include 3 Fatty Acid supplementation is able to
cholesterol and various other fats, including preserve the normal proliferation rate of
omega-3 and omega-6 oils.  A high skin cells (14), which makes it useful in
accumulation of certain fats can bog down maintaining supple, healthy and vibrant skin.
the vital processes of cellular communication
and processing of toxins.  Omega-3 fats are
preferentially incorporated into the cell
membranes because they can increase the
efficiency and fluidity of the cells, thereby
allowing them to perform their various tasks. 
A deficiency of omega-3 oils in the diet
causes the operation of these cells to bog
down. A number of studies have shown
that supplemental omega-3 oils become
incorporated into various cellular
membranes by displacing other less
desirable fats and cholesterol molecules.
(11) By affecting these important functions,
supplementation of omega-3 oils can support
cellular health and communication.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Purity Products 4
Omega-3 Research Spotlight June 2007, Vol 1

the benefits of fish oil

Summary
The benefits of DHA and EPA-rich fish
oil are numerous. Science continues to affirm
that these Omega-3 Fatty Acids have the
potential to positively influence many organs
and tissues. By properly supplementing a
healthy diet with Omega-3 Oils from fish,
one can support the optimal functioning of
the heart, brain, bones, joints, skin and just
about every cell in the body.*  Journal of Clinical Nutrition, Vol. 77, February 2003, pp.
References
1) Harris, WS, et al. Omega-3 fatty acids in cardiac
biopsies from heart transplantation patients: correlation
with erythrocytes and response to supplementation.
Circulation, Vol. 110, September 21, 2004, pp. 1645-49
2) A
 lbert, CM, et al. Blood levels of long-chain n-3 fatty
acids and the risk of sudden death. N Engl J Med 2002;
346:1113-8.
3) I so, H, et al. Intake of fish and omega-3 fatty acids and risk
of stroke in women. JAMA 2001;285:304-312.
4) L
 emaitre, RN, et al. n-3 polyunsaturated fatty acids, fatal
ischemic heart disease, and nonfatal myocardial infarction
in older adults: the Cardiovascular Health Study. American
319-25

Top 10 Fish Oil Benefits 5) S ingh M. Essential fatty acids, DHA and human brain. 
Indian J Pediatr. 2005 Mar;72(3):239-42.
1. F
 ish oils comprehensively support healthy 6) H
 eude B, Ducimetiere P, Berr C. Cognitive decline and fatty
acid composition of erythrocyte membranes—The EVA
heart and cardiovascular function* Study. Am J Clin Nutr. 2003 Apr;77(4):803-8.
2. F
 ish oils enhance the structure and 7) K
 almijn S, et al. Dietary intake of fatty acids and fish in
relation to cognitive performance at middle age. Neurology.
function of cellular membranes* 2004 Jan 27;62(2):275-80.
3. E
 PA and DHA promote healthy brain 8) H
 ibbeln, Joseph R. Fish consumption and major
depression. The Lancet, Vol. 351, April 18, 1998, p. 1213
development* (correspondence)
4. E
 PA and DHA support healthy cognitive 9) K
 aufman, Marc (1999), “Fish oil may aid against manic
function and enable efficient cell-to-cell depression”, The Washington Post, 27 Apr, Health
section.
function*
10) C
 urtis CL, et al. Effects of n-3 fatty acids on cartilage
5. Fish oils support healthy circulation* metabolism. Proc Nutr Soc. 2002 Aug;61(3):381-9.
11) H
 ashimoto, M, et al. Effects of eicosapentaenoic acid and
6. E
 PA and DHA may enhance healthy docosahexaenoic acid on plasma membrane
vision by promoting normal retinal fluidity of aortic endothelial cells. Lipids. 1999; 34(12):
1297-1304.
function*
12) Z
 iboh VA, et al. Metabolism of polyunsaturated fatty acids
7. E
 PA and DHA enhance free radical by skin epidermal enzymes: generation of
antiinflammatory and antiproliferative metabolites. Am J
scavenging in tissues and organs* Clin Nutr. 2000 Jan;71(1 Suppl):361S-6S.
8. O
 mega-3 fatty acids enhance the function 13) S torey A, et al. Eicosapentaenoic acid and
of complex signaling pathways in the docosahexaenoic acid reduce UVB- and TNF-alpha-induced
IL-8 secretion in keratinocytes and UVB-induced IL-8 in
human body* fibroblasts. J Invest Dermatol. 2005 Jan;124(1):248-55.

9. O
 mega-3 fatty acids enhance the cellular 14) M
 ayser P, et al. Omega-3 fatty acid-based lipid
infusion in patients with chronic plaque psoriasis: results of
uptake of vital nutrients* a double-blind, randomized, placebo-
controlled, multicenter trial. J Am Acad Dermatol. 1998
10. E
 PA and DHA promote vibrant and Apr;38(4):539-47
youthful skin*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Purity Products 5
Omega-3 Research Spotlight June 2007, Vol 1

the benefits of fish oil

The research is in and it is clear that

supplementing your diet with Omega-3 Fish Oils
is crucial in maintaining overall good health.*
Numerous studies conclude that Omega-3 Fish
Oils can have a positive impact on the optimal

• heart* • joints*
• brain* • skin*
• bones* • cells*

Purity’s Quality Promise - Purity’s Omega-3 contains only the highest

grade, concentrated, ultra purified, molecularly distilled, lemon flavored
Omega-3 soft gels.

200 Terminal Drive • Plainview, NY 11803

Order Line: 1-800-281-7781
Customer Care: 1-888-769-7873
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Purity Products 6