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one molecule of FAD is reduced to FADH2 . These molecules then transfer their energy to the electron transport chain, a pathway that is part of the third stage of cellular respiration. The electron transport chain in turn releases energy so that it can be converted to ATP through the process of oxidative phosphorylation.
The German-born British biochemist Sir Hans Adolf Krebs proposed this cycle, which he called the citric acid cycle, in 1937. For his work he received the 1953 Nobel Prize in Physiology or Medicine. Although Krebs elucidated most of the reactions in this pathway, there were some gaps in his design. The discovery of coenzyme A in 1945 by Fritz Lipmann and Nathan Kaplan allowed researchers to work out the cycle of reactions as it is known today.
"tricarboxylic acid cycle". Encyclopdia Britannica. Encyclopdia Britannica Online. Encyclopdia Britannica Inc., 2012. Web. 19 Dec. 2012 <http://www.britannica.com/EBchecked/topic/604852/tricarboxylic-acid-cycle>.
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