‫) ) في الدواجن‬IB ‫تقرير لبرنامج التطعيم ضد ال‬

‫والسللت المسببه للمرض والسللت المستخدمه في التطيعم‬

‫ خالد إبراهيم احمد الشرفا‬: ‫السم‬

‫فلسطيني‬:‫الجنسيه‬
‫ نابلس – بيتا‬:‫المدينه‬

‫كليه الطب البيطري جامعة النجاح الوطنية‬

Name : khaled Ibrahim AL-shorafa

Palestinian young
From nablus city-baita

College of veterinary medicine AL- najah

national university

Infectious bronchitis vaccination programe

))IB

Email address: palestinekh@hotmail.com

 Infectious Bronchitis vaccination program
IB((

IB( it is an important disease in poultry production . it cause(

large economic losses in Broilers , Layers and breeders .these
. disease affect respiratory system , kidneys, and oviduct

Aim of vaccination against Infectious Bronchitis

It is important to establish the purpose of vaccination.

Broilers - Vaccination is focused on reducing the economic

losses caused by IB infections as these are reflected in weight
loss and general poor performance of the flock.

Layers and breeders - The aim of vaccination is to protect

the oviduct as IB infections may result in false layers, drops in
production and changes in the internal and external quality of
the eggs.

In this context vaccination of young chickens is often done at an

early age (first day(s( of life(, and especially in broilers focusing
on inducing enough protection so as to cover the whole fattening
period. In layers and breeders the programs are focused in
protecting the oviduct during the first weeks of life with
modified live vaccines. Later on during the production period
immunity needs to be broad and long lasting, and inactivated
vaccines are often used.

: Etiologic agent
the Disease caused by virus belong to coronavirus super
family, (IB( virus is antigenically distinct from other
:coronaviruses , the virus had eight classical types
.Massachusetts -1
.Connecticute -2
.Georgea -3
.Delware -4
.Iowa 97 -5
.Iowa 609 -6
.New Hampshire -7
.(Australian(T-strain -8

These serotypes participate in one specific antigen which we

can detect by using; agar gel precipitation (AGP(test, serum
.(neutralizing test(SN(,and (ALLISA
Every type of these types give Homologus Protection , if there
infection or vaccination for one type it give complete
immunity for the same type only, and if there an infection or
vaccination of one type these don’t give complete immunity for
.other types

and it consist of Variant Types which is cause different

symptoms, it don’t give certain disease.
-1D 207
-2D 3896
3-D 3128
4-D 212 . - 5 D-274

Vaccines:
No general vaccination rule can be applied. Each vaccination
program must be adapted to the demands of the field
situation.Some considerations have to be taken into account
when applying IB vaccines:

I-(IB( strains variant, so there no ideal strain for vaccination

against (IB(, the most proper vaccine used should be isolated
from same Geographic area (autogenously(, there some strains
give broad protection against (IB( but not complete protection.

II-At what age protection against Infectious Bronchitis (IB( is

most needed.

III-The field situation .

VI-Interference viruses present will determine which vaccines
(protectotype( to choose with other (live( vaccinations must be
avoided (IB vaccine viruses can interfere with for example
Newcastle disease vaccine viruses(.

V-Geographic area .

Used Vaccines:
I- live vaccines: it given in drinking water, aerosol , drops in
nostril or eye. The live vaccine include the following: )H120(
attenuated Massachusetts live vaccine is attenuated by serial
passage the strain in emroynated eggs 120 time, the (H120(
vaccine give good immunity but to short time :and so we
revaccinate with other dose after 6-8 weeks from the first dose
these dose we use (H52( Massachusetts live vaacines is
attenuated by serial passage the with emroynated eggs 52 time,
so (H52( more virulence than the (H120( . (H52( use only in the
second dose after using (H120( in the first dose.

The serial passage of vaccine in embryonated eggs is

procedure used in production of live attenuated vaccines , these
serial passage reduce pathogenicity but also increase
immunogenicity.

Other type of live vaccine Connecticut3 serotype ;it attenuated

serotype has the same effect like (H120(, but Connecticut3 don’t
give wide range of protection like Massachusetts serotypes
.witch give wide range of protection for other (IB( virus strains

The fourth type of vaccines is K-vaccine, witch consist of tow

types,K50,K100,these it consist from three strains
101+L535+0728, it use in livestock that infected with these
strains(autogenously( , it give protection for D-274 variant strain
and other variantstrianes, we vaccinate with these vaccine in 10
weeks ,there some companies produce these vaccine mixed with
.H120
II- inactivated vaccines : it produced by the most of
.companies in world
.oily vaccines, using Massachusetts serotype -1
there is accompanies produce Massachusetts serotype mixed -2
. with other variant serotypes
there some Companies produce the vaccines for (IB( -3
separated, and sometimes add the vaccine for other dead
.Newcastle disease and(IBD( to be one dual-purpose or three

Vaccination programs in layers , broilers breeders ,

-:and broilers

I- vaccination in broilers breeders: the aim of vaccination

against IB in breeders to protect their oviducts and give high
.titer of maternal antibodies to their progeny
In the first day the vaccination with H120 live vaccine by
.aerosol , or in 3 to 4 weeks by aerosol or drinking water
After the first dose that inactivated vaccine is given
.intramuscularly twice in 8-16 weeks

II- vaccination in broilers: the vaccination with H120 is

enough after hatching or in 2 – 3 weeks of age . but farms with
high distribution of disease the vaccination twice in first day and
. after 3 weeks

III- vaccination in layers : three doses of the vaccine is

used, that give good immunity before start in egg production to
.prevent drop in egg production
The first dose in first day with H120 by aerosol or in 3-4 weeks
. by aerosol or in drinking water
. The second dose in 8-12 weeks with H120 or H52
The third dose 14 -18 weeks by using inactivated vaccine giving
.intramuscularly
:PRECAUTIONS
Vaccinate only healthy chickens. Although disease may
not be evident, coccidiosis, mycoplasma infection,
infectious bursal disease, Marek’s disease and other
disease conditions may cause complications or reduce
.immunity
All susceptible chickens on the same farme should be
.vaccinated at the same time
Efforts should be taken to reduce stress conditions at the
.time of vaccination and during the reaction period

DVM: khaled ibrahim hammad AL-shorafa