The Assurance Minerals

Dr Ganesh K Saini Product Manager - Poultry

 Essential inorganic nutrients, required in small amounts Required for growth, maintenance, reproduction and production (Egg & Meat)

Classified into two groups:

Macro or major elements (required > 100 ppm)

7 macro minerals are Ca, P, Mg, Na, K, Cl and S

Micro or trace mineral elements (required <100 ppm)

The 18 trace elements are Fe, Cu, Co, Zn, I, Mn, Se, Mo, Cr, F, Ni, Va, Si, Pb, Hg, Cd, Sn and As.

Soil

Plant

Relationship

Bird

Emerging Nutrient Deficiencies in soils as a Result of Increased Food Production (Swarup & Ganeshamurthy, 1998)

Year Food Production

1950 50mt

1960 70mt

70 108

80 112

1990 172

2000 209mt

N
Emerging Nutrient Deficiencies ?

N Fe

N Fe P Zn K

N Fe P Zn K S Mn

N Fe P Zn K S Mn B

N Fe P Zn K S Mn B

Mineral Deficiency in feeds All India

REGIONS
Northern

Minerals deficient in feeds

Ca , P , Mg, Zn ,Cu, Mn, I,

Western
Southern

Ca, P, S, Cu, Zn,

Ca, P, Mg, Cu, Zn,

Eastern

Ca, P, Mg, Mn, Cu, Zn, Co,

How to Interpret the Mineral Wheel

The arrows indicate the relationship between the minerals. If a mineral has an arrow pointing to another mineral, it indicates that mineral is a requirement for absorption.

Mineral Deficiency Response

Immune Function
Mineral Status

Growth or Fertility

Clinical Signs

Sub-Clinical
Time

Clinical

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TRACE MINERAL ABSORPTION

Outcome 1. Excretion

Ingested

Zn+
2

Zn+
2

Gut Wall
Blood

CB - 50

Outcome 2. Excretion

Ingested

Zn+
2

Zn+ 2

Zn+
2

Antagonist

Gut Wall
Blood

CB - 50

Outcome 3.

Natural Success

Ingested

Zn+
2

Zn+
2

Complexing Agent

Zn+
2

Gut Wall

Blood

Zn+
2

CB - 50

Engineered for Success

Ingested

Zn+
2

Zn+
2

Zn+
2

Gut Wall Zn+ BLOOD Zn+

2 2

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What about Chelation?

Chelation . . . The process by which metal ions form a complex with an organic ligand via a coordinate bond.

From: Holwerda, R. A., R. C. Albin and F. C. Madsen (1995) Chelation effectiveness of zinc proteinates demonstrated, Feedstuffs, June 19, 1995, 12-13 and 23.
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Assured Response

Assured Results
Assured Bioavailability Assured Returns

Amino Acid

Complexed to Metal

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TRACE MINERALS ARE NOT THE SAME

Sulfates EDTA Proteinates complex Carbonates Chelates

Oxides
Chlorides

DIFFERENTIATION OF ORGANIC TRACE MINERALS

Metal (Specific Amino Acid) Complex

Zn

Zn

Met

AA

Metal Amino Acid Chelate

AA

Zn

Zn

AA
AA

AA

AA

Metal Amino Acid Chelate

Zn

AA AA

AA

AA AA

Metal Proteinate

AA AA AA AA AA A AA AA AA A

AA AA
Zn

AA AA

AA

Metal Polysaccharide Complex

Zn

Zn Zn Zn Zn Zn Zn Zn Zn Zn

Zn

Metal Propionate

Prop.-1
Zn+2

Prop.-1 Zn

Zn Zn Zn Zn

CPX - 22

SIZE MATTERS
Need to be <360
daltons.
Webb et. al. 1992

Absorption

SMALLER IS BETTER!

ORGANIC TRACE MINERAL COMPARISON

(Based on AAFCO)

360 Daltons

PROTEINATE

M
1065 Daltons

AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein

THIS IS ALSO A PROTEINATE

6365 Daltons

AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein

DIGESTION
Most Large Peptides and Protein Ligands will be Broken Into Single Amino Acids, Di- or Tripeptides for absorption The Digestion Process Will Destroy the Weak Bond Between the Metal and the Peptide or Protein Ligand

Z CPX - 38

Science also confirms that as the ligand size increase the ability of the ligand to form a strong bond decrease rapidly.
Relative Stability Constant of OTM
120
Relative Stability Constant %

100 80 60 40 20 0

Stability Constant %

Amino Acid Di- Peptide Tri- Peptide Peptide (4 AA)

Peptide (5 AA)

LIGAND TYPE

FORMULATION STRATEGIES FOR LOWERING TRACE MINERAL SUPPLEMENTATION LEVELS

Complexes Parameter

Inorganic Inorganic + Antagonists

Increasing Trace Mineral Level Nutrient Utilization Performance Immunity

CB - 42.2

Status vs. Time and Level Single Source - All Complexes Environment

Parameters Type Metal Bond

Methomin Amino acid Chelate 1:2 (metal: AA)

Bioplex Proteinate Metal bonded with a protein molecule

Molecule Size Composition

Below 360 dalton

More than 1000 dalton 40,40,5,15 of Zinc, Manganese, Copper and Iron respectively.; Iodine and chromium thru inorganic route and Se thru Selenium yeast route.

Research

Published data mostly in popular magazines

STANDARD MINERALS

Assurance
MINERALS

Prevent Deficiency Normal growth Normal Repro Normal immunity

Increased growth Improved Efficiency Improved Reproduction Improved immunity

Assured Response Assured Results Assured Bioavailability Assured Returns

Methomin SPL
Per Kg METHOMIN TOTAL Contains

Zinc Manganese Copper Iron Chromium Iodine Selenimum Cobalt

40 grams 40 grams 10 grams 12 grams 250 mg 4 grams 300 mg 250 mg

Mixing Rate : 0.5 - 1 Kg / MT

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Advantage of Methomin
Egg quality: shell quality,albumin quality,nutritional value of egg, free from defects. Zinc helps in activation of carbonic anhydrase and formation of cuticle Blood plasma - shell gland - egg shell

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Benefits
Source of methionine. Reduction in egg shell breakage. Improvement in egg shell quality. Improvement in hatchability Growth and feed efficiency. Improves egg production. Better performance during heat stress

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MHA V/S DLM

MHA
Absorbed throughout the intestinal tract Absorption is a passive process Converted to L-methionine much faster Absorption is unaffected by heat stress Non-toxic at higher doses

DLM
Absorbed mainly in the ileum Is active process Comparatively slower conversion Decreases during heat stress Toxic at higher doses

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Objective
1. Reduction of antagonism, interferences and competition among

minerals.
2. Improve the bioavailability of minerals 3. Counteract antinutritional factors, which affecting minerals

4. Performance improvement
5. Health improvement (immune status, functional nutrition) 6. Over all animal welfare 7. Improvement in animal produces quality (meat, milk, egg, wool etc.,) 8. Reduce degenerative effect of trace minerals on vitamins in premixes feed. 9. Protect environment by reducing metal pollution.

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Mixing Rate and Presentation

Mixing Rate : Poultry -0.5-1Kg/ton of feed As recommended by the Nutritionist

Presentation : 25Kg.

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