Tumor Markers

Tumor marker Alpha fetoprotein (AFP) CA15-3 CA27-29 CA19-9 CA-125 Calretinin Carcinoembryonic antigen CD34 CD99 CD117 Chromogranin Cytokeratin (various types) Desmin Epithelial membrane protein (EMA) Factor VIII, CD31 FL1 Glial fibrillary acidic protein (GFAP) Gross cystic disease fluid protein (GCDFP-15) HMB-45 Human chorionic gonadotropin (hCG) immunoglobulin inhibin keratin (various types) Associated tumor types germ cell tumor, hepatocellular carcinoma[5] breast cancer[6] breast cancer Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer.[7] Mainly ovarian cancer,[8] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer.[9] May also increase in endometriosis.[10] mesothelioma, sex cord-gonadal stromal tumour, adrenocortical carcinoma, synovial sarcoma[5] gastrointestinal cancer, cervix cancer, lung cancer, ovarian cancer, breast cancer, urinary tract cancer[5] hemangiopericytoma/solitary fibrous tumor, pleomorphic lipoma, gastrointestinal stromal tumor, dermatofibrosarcoma protuberans[5] Ewing sarcoma, primitive neuroectodermal tumor, hemangiopericytoma/solitary fibrous tumor, synovial sarcoma, lymphoma, leukemia, sex cord-gonadal stromal tumour[5] gastrointestinal stromal tumor, mastocytosis, seminoma[5] neuroendocrine tumor[5] Many types of carcinoma, some types of sarcoma[5] smooth muscle sarcoma, skeletal muscle sarcoma, endometrial stromal sarcoma[5] many types of carcinoma, meningioma, some types of sarcoma[5] vascular sarcoma[5] glioma (astrocytoma, ependymoma)[5] breast cancer, ovarian cancer, salivary gland cancer[5] melanoma, PEComa (for example angiomyolipoma), clear cell carcinoma, adrenocortical carcinoma[5] gestational trophoblastic disease, germ cell tumor, choriocarcinoma[5] lymphoma, leukemia[5] sex cord-gonadal stromal tumour, adrenocortical carcinoma, hemangioblastoma[5] carcinoma, some types of sarcoma[5]

PTPRC (CD45) lymphocyte marker (various types MART-1 (Melan-A) Myo D1 muscle-specific actin (MSA) neurofilament neuron-specific enolase (NSE) placental alkaline phosphatase (PLAP) prostate-specific antigen S100 protein smooth muscle actin (SMA) synaptophysin thyroglobulin thyroid transcription factor-1 Tumor M2-PK vimentin

lymphoma, leukemia, histiocytic tumor[5] lymphoma, leukemia[5] melanoma, steroid-producing tumors (adrenocortical carcinoma, gonadal tumor)[5] rhabdomyosarcoma, small, round, blue cell tumour[5] myosarcoma (leiomyosarcoma, rhabdomyosarcoma)[5] neuroendocrine tumor, small-cell carcinoma of the lung[5] neuroendocrine tumor, small-cell carcinoma of the lung, breast cancer[5] seminoma, dysgerminoma, embryonal carcinoma[5] prostate[5] melanoma, sarcoma (neurosarcoma, lipoma, chondrosarcoma), astrocytoma, gastrointestinal stromal tumor, salivary gland cancer, some types of adenocarcinoma, histiocytic tumor (dendritic cell, macrophage)[5] gastrointestinal stromal tumor, leiomyosarcoma, PEComa[5] neuroendocrine tumor[5] thyroid cancer (but not in medullary thyroid cancer)[5] all types of thyroid cancer, lung cancer[5] colorectal cancer,[11] Breast cancer,[12][13] renal cell carcinoma[14][15] Lung cancer,[16][17] Pancreatic cancer, [18] Esophageal Cancer,[19] Stomach Cancer,[19]Cervical Cancer,[20] Ovarian Cancer,[21] sarcoma, renal cell carcinoma, endometrial cancer, lung carcinoma, lymphoma, leukemia, melanoma[5]