Polyfuse

Polyfuses is a new standard for circuit protection .It is re-settable by itself. Many manufactures also call it as Polyswitch or Multifuse. Polyfuses are not fuses but Polymeric Positive temperature Coefficient Thermistors (PPTC). We can use several circuit protection schemes in power supplies to provide protection against fault condition and the resultant over current and over temperature damage. Current can be accomplished by using resistors, fuses, switches, circuit breakers or positive temperature coefficient devices. Resistors are rarely an acceptable solution because the high power resistors required are expensive .One shot fuses can be used but they might fatigue and they must be replaced after a fault event. Another good solution available is the resettable Ceramic Positive Temperature Coefficient (CPTC) device. This technology is not widely used because of its high resistance and power dissipation characteristics. These devices are also relatively large and vulnerable to cracking as result of shock and vibration. The preferred solution is the PPTC device, which has a very low resistance in normal operation and high resistance when exposed to fault. Electrical shorts and electrically overloaded circuits can cause over current and over temperature damage. Like traditional fuses, PPTC devices limit the flow of dangerously high current during fault condition. Unlike traditional fuses, PPTC devices reset after the fault is cleared and the power to the circuit is removed. Because a PPTC device does not usually have to be replaced after it trips and because it is small enough to be mounted directly into a motor or on a circuit board, it can be located inside electronic modules, junction boxes and power distribution centers. THE BASICS Technically Polyfuses are not fuses but Polymeric Positive Temperature Coefficient Thermistors. For thermistors characterized as positive temperature coefficient, the device resistance increases with temperature. The PPTC circuit protection devices are formed from thin sheets of conductive semi-crystalline plastic polymers with electrodes attached to either side. The conductive plastic is basically a non-conductive crystalline polymer loaded with a highly conductive carbon to make it conductive. The electrodes ensure the distribution of power through the circuit. Polyfuses are usually packaged in radial, axial, surface mount, chip or washer form. These are available in voltage ratings of 30 to 250 volts and current ratings of 20 mA to 100A. PRINCIPLE OF OPERATION PPTC circuit protection devices are formed from a composite of semi-crystalline polymer and conductive carbon particles. At normal temperature the carbon chains form low resistance conductive network through the polymer. In case an excessive current flows through the device, the temperature of the conductive plastic material rises. When the temperature exceeds the device's switching temperature, the crystallides in the polymer suddenly melts and become amorphous. The increase in volume during melting of the crystalline phase cause separation of the conductive particles and results in a large non-linear increase in the resistance of the device. The resistance typically increases by 3 or orders of magnitude.

Bioinformatics

Introduction
Rapid advances in bioinformatics are providing new hopes to patients of life threatening diseases. Gene chips will be able to screen heart attack and diabetics years before patients develop symptoms. In near future, patients will

go to a doctor's clinic with lab- on- a- chip devices. The device will inform the doctor in real time if the patient's ailment will respond to a drug based on his DNA. These will help doctors diagnose life-threatening illness faster, eliminating expensive, time-consuming ordeals like biopsies and sigmoidoscopies. Gene chips reclassify diseases based on their underlying molecular signals, rather than misleading surface symptoms. The chip would also confirm the patient's identity and even establish paternity. Bioinformatics is an inter disciplinary research area. It is a fusion of computing, biotechnology and biological sciences. Bioinformatics is poised to one of the most prodigious growth areas in the next to decades. Being the interface between the most rapidly advancing fields of biological and computational sciences, it is immense in scope and vast in applications. Bioinformatics is the study of biological information as it passes from its storage site in the genome to the various gene products in the cell. Bioinformatics involves the creation and computational technologies for problems in molecular biology. As such ,it deals with methods for storing, retrieving and analyzing biological data, such as nuclei acid (DNA/RNA)and protein sequence, structures, functions, path ways and interactions. The science of Bioinformatics, which is the melding of molecular biology withcomputer science is essential to the use of genomic information in understanding human diseases and in the identification of new molecular targets of drug discovery. New discoveries are being made in the field of genomics, an area of study which looks at the DNA sequence of an organism in order to determine which genes code for beneficial traits and which genes are involved in inherited diseases.If you are not tall enough, the stature could be altered accordingly. If you are weak and not strong enough, your physique could be improved. If you think this is the script for a science fiction movie, you are mistaken. It is the future reality. Evolution Of Bioinformatics DNA is the genetic material of organism. It contains all the information needed for the development and existence of an organism. The DNA molecule is formed of two long polynucleotide chains which are spirally coiled on each other forming a double helix. Thus it has the form of spirally twisted ladder. DNA is a molecule made from sugar, phosphate and bases. The bases are guanine (G), cytosine(C)adenine(A) and thiamine(T).Adenine pairs only with Thiamine and Guanine pairs only with Cytosine. The various combinations of these bases make up with DNA. That is; AAGCT, CCAGT,

TACGGT etc. An infinite number of combinations of these bases is possible. And then the gene is a sequence of DNA that represents a fundamental unit of heredity. Human genome consists of approximately 30,000 genes, containing approximately 3 billion base pairs. Nanotechnology

Definition
Nanotechnology is defined as fabrication of devices with atomic or molecularscale precision. Devices with minimum feature sizes less than 100 nanometers (nm) are considered to be products of nanotechnology. A nanometer is one billionth of a meter (10-9 m) and is the unit of length that is generally most appropriate for describing the size of single molecules. The nanoscale marks the nebulous boundary between the classical and quantum mechanical worlds; thus, realization of nanotechnology promises to bring revolutionary capabilities. Fabrication of nanomachines, nanoelectronics and other nanodevices will undoubtedly solve an enormous amount of the problems faced by mankind today.

Nanotechnology is currently in a very infantile stage. However, we now have the ability to organize matter on the atomic scale and there are already numerous products available as a direct result of our rapidly increasing ability to fabricate and characterize feature sizes less than 100 nm. Mirrors that don't fog, biomimetic paint with a contact angle near 180, gene chips and fat soluble vitamins in aqueous beverages are some of the first manifestations of nanotechnology. However, immenant breakthroughs in computer science and medicine will be where the real potential of nanotechnology will first be achieved. Nanoscience is an interdisciplinary field that seeks to bring about mature nanotechnology. Focusing on the nanoscale intersection of fields such as physics, biology, engineering, chemistry, computer science and more, nanoscience is rapidly expanding. Nanotechnology centers are popping up around the world as more funding is provided and nanotechnology market share increases. The rapid progress is apparent by the increasing appearance of the prefix "nano" in scientific journals and the news. Thus, as we increase our ability to fabricate computer chips with smaller features and improve our ability to cure disease at the molecular level, nanotechnology is here.

History of Nanotechnology
The amount of space available to us for information storage (or other uses) is enormous. As first described in a lecture titled, 'There's Plenty of Room at the Bottom' in 1959 by Richard P. Feynman, there is nothing besides our clumsy size that keeps us from using this space. In his time, it was not possible for us

to manipulate single atoms or molecules because they were far too small for our tools. Thus, his speech was completely theoretical and seemingly fantastic. He described how the laws of physics do not limit our ability to manipulate single atoms and molecules. Instead, it was our lack of the appropriate methods for doing so. However, he correctly predicted that the time would come in which atomically precise manipulation of matter would inevitably arrive. Prof. Feynman described such atomic scale fabrication as a bottom-up approach, as opposed to the top-down approach that we are accustomed to. The current top-down method for manufacturing involves the construction of parts through methods such as cutting, carving and molding.