Hematologic

System

Endocrine System Anemia Muscular System

Uremia
Fever Muscle weakness
Cannot stimulate
kidney for the
production of
erythropoetin Nervous System

Lethargy
Lymphatic System Decrease level of
consciousness
Decrease
production of
RBC in the bone
marrow Respiratory System

Pulmonary
edema
Digestive System Dsypnea
SIGNS & SYMPTOMS
Loss of appetite of WILMS TUMOR
Constipation
Nausea and
vomiting Cardiovascular
System

High blood
Urinary System pressure

Hematuria
Ischemia
GU defects
Integumentary
System

Reproductive Itching
System Pallor
Edema
GU defects Pruritus
Skeletal System

Pain at the joint

BODY SYSTEM SIGNS & SYMPTOMS RATIONALE
Endocrine > fever > unknown reason
System > cannot stimulate the > due to the kidney cannot perform
kidney for the its function well
production of
erythropoietin
Lymphatic > decrease production > due to the decrease or absence of
System of RBC in the bone erythropoietin hormone which helps
marrow the bone marrow in the production of
RBC
> ascites > accumulation of fluid in the
peritoneal cavity due to excessive
fluid in the body
Digestive > loss of appetite > because any fever may cause
System temporary loss of appetite and all the
nutrient that suppose to be for the
body is being eaten by the tumor cells
> constipation > due to infants who are still
exclusively breastfed may go 7 days
without a stool (for infant patients)
and also due to the fluid imbalance in
the digestive system
> nausea and vomiting > due to uremia the body compensate
by excreting the toxins through
vomiting
Urinary System > hematuria (blood in > indicates that blood has passed
the urine) through the tubule
> ischemia > due to its increasing tumor cells,
compressing the surrounding tissue
> GU defects (in terms > due to blockage of tumor cells in
of excretory) the urine way the urine output
decreases
Reproductive > GU defects (in terms > the genital decreases the urine
System of genital) output due to the CREA which is
suppose to be excreted is reabsorb
again and goes into the circulation.
Skeletal System > pain at the joint > occur only when metabolic process
is affected
Integumentary > itching > due to the CREA that is not
System excreted, can expel out by
perspiration which is very irritating
> pallor > due to urochrome retention
> edema >due to Na and water retention from
reduced glomerular filtration rate
>pruritus > may be associated with
hyperphosphatemia that results from
renal failure
Cardiovascular > high Blood Pressure > due to Na and water retention from
 System reduced glomerular filtration rate
Respiratory > pulmonary edema > results from excessive fluid in the
System body that reaches in the lungs
> dyspnea > that results from pulmonary edema
Nervous System > decrease level of > due to electrolyte imbalance
consciousness
> lethargy > mental and physical sluggishness
Muscular > muscle weakness > due to electrolyte imbalance,
System atrophy and collection of uremic
toxins
Hematologic > anemia > due to erythropoietin are not
System produce which helps bone marrow to
make RBC
> Uremia > presence of abnormal levels of urea
and other nitrogenous products in the
blood due to the kidney cannot
excrete it