AQUEOUS LEAF EXTRACT OF SIKERPUD,Biophytum sensitivum Linn.

(OXALICIDEAE) TO REDUCE BLOOD SUGAR IN MICE

A Special Problem Presented To The Faculty of the Graduate Studies Mindanao State University Naawan Naawan, Misamis riental

!n Partial Fulfillment of the "e#uirements For the $e%ree Master of &iolo%y

WILFREDO RIVERA JABINES Ap i! "#$%

The Master's Special p" &()M attached hereto entitled *A+U) US ()AF ),T"A-T F S!.)"PU$, Biophytum sensitivum / ,A(!-!$)A)0 T ")$U-) &( $ SUGA" !N M!-)1 prepared and submitted by 2ilfredo "3 4abines in partial fulfillment of the re#uirements for the de%ree of Master in &iolo%y was successful defended and approved on March 56, 57783

&ELEN J. VICENTE, P'.D. Adviser

GRACE I. PRADO Member

This Master's Special Problem is hereby officially accepted as partial fulfillment of the re#uirements for the de%ree of Master of &iolo%y3

JESSIE G. GOROSPE, P'.D. $ean of School of Graduate Studies

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ACKNOWLEDGMENT

The author e9pressed his %ratitude to the followin% persons whom in one way or another he owed effort, moral, spiritual, and financial support to ma:e his study successful in the end3 $r3 ;elen 43 <icente for the %uidance and the e9pertise shared that provided the vital framewor: of the study3 $r3 4essie G3 Gorospe, for the constant reminders= ;is wife, "ebecca, for the encoura%ement, love, spiritual and moral support to %ive inspiration and more meanin%s in his life= ;is children> <ernun Gustavio and (ourd Patrice for the inspiration as the special %ifts of love= The late $r3 -esar $3 Padero%, the former school head of Mat?i /Naawan0 National ;i%h School, for the continued support= Mrs3 4anit A3 (lanita, his co?teacher for the wishes and prayers= Mrs3 (ilia &a%ares, for the constant company= and Above all, his -reator for ma:in% everythin% possible under ti%ht circumstances3

2!(F")$

"3 4A&!N)S

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BRIEF CURRICULUM VITAE

NAM) ; M) A$$")SS $AT) F &!"T; P(A-) F &!"T; PA")NTS SP US) -;!($")N P S!T! N ;)($ >2ilfredo "ivera 4abines >Puro: @, Poblacion, Naawan, Misamis riental >September 5A, 6B8C >"amon Ma%saysay, Damboan%a del Sur >"estituto "ubillar 4abines and Patrocenia (ubiranes "ivera >"ebecca "iEardo 4abines ><ernun Gustavio "3 4abines and (ourd Patrice "3 4abines >Teacher !!!

EDUCATIONAL ATTAINMENT(&ONORS(AWARDS RECEIVED

)lementary >-ampo < )lementary School -ampo <, "amon Ma%saysay, Damboan%a del Sur March 6BF8 >!mmaculate ;eart Academy Poblacion, $umalinao, Damboan%a del Sur March 6B@6 >Mindanao State University at Naawan School of Marine Fisheries and Technolo%y &achelor of Science in Marine &iolo%y April 6B@@ >Mindanao State University at Naawan School of Marine Fisheries and Technolo%y Master of &iolo%y April 5765

Secondary

-olle%e

Graduate

SELECTED TRAINING AND WORKS&OPS ATTENDED

>"escue !nitiative in Science )ducation ?"!S), /Teacher Trainin% in Science and Technolo%y0, April 58?May 7@, 577G Up%radin% )ducation for Teachers Teachin% Science and Mathematics, 577F? 577@

M)M&)"S;!P !N P" F)SS! NA(

"GAN!DAT! N
ro -ity -hapter

>&iolo%y Teachers Association of the Philippines? -a%ayan de

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ABSTRACT

Teen youn% mice treated with a a#ueous leaf e9tract of Si:erpud, &iophytum sensitivum from a standard amount of C7% of dried leaves boiled in A77m( of hot water3 From initial "&S test before treatment was found out that the readin% of blood su%ar in mice is lower than after treatment of the a#ueous leaf e9tract3 -onsiderin% the positive result in the e9periment, it is indicative that &3 sensitivum can reduce the blood su%ar in mice so it can be used to treat for human diabetes mellitus3

TABLE OF CONTENTS

Pa%e
A&ST"A-T (!ST F TA&()S (!ST F F!GU")S (!ST F APP)N$!-)S 63 !NT" $U-T! N 6363 "ationaleHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH3 6 6353 General bIectiveHHHHHHHHHHHHHHHHHHHHHHHHHHH33 C 63C3 Specific bIectiveHHHHHHHHHHHHHHHHHHHHHHHHHHH333 63G3 Si%nificance of the StudyHHHHHHHHHHHHHHHHHHHHHHHHH 63A3 (imitation of the StudyHHHHHHHHHHHHHHHHHHHHHHHHHH 6383 ;ypothesisHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 5373 MAT)"!A(S AN$ M)T; $S 5363 )9perimental $esi%n33HHHHHHHHHHHHHHHHHHHHHHHHHH 5353 Plant -ollectionHHHHHHHHHHHHHHHHHHHHHHHHHHHH33 5353 Plant PreparationHHHHHHHHHHHHHHHHHHHHHHHHHHHH 53C3 Preliminary Test for Standard -oncentrationHHHHHHHHHHHHHHHH3 C373 ")SU(TSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH33 G373 $!S-USS! NHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH A373 SUMMA"J AN$ - N-(US! NHHHHHHHHHHHHHHHHHHHHHHHHH 8373 ")- MM)N$AT! N AN$ !MP(!-AT! NHHHHHHHHHHHHHHHHHHHH3 ")F)")N-)S APP)N$!-)S

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LIST OF TABLES

Table No3 6 5 C G 3 A

$escription Milestone in the Study of ;erbal MedicinesHHHHHHHH Photochemical StudiesHHHHHHHHHHHHHHHH3 Pharmacolo%yK Fol:loric Medicine HHHHHHHHHHH3 Preliminary "andom &lood Su%ar /"&S0 TestHHHHHH3 "andom &lood Su%ar "esults /"&S0 Usin% the Standard -oncentration HHHHHHHH33

Pa%e

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Li)* +, Fi-. /)

Fi%ure No3 6 5 C G A 8 F @ B 67 66

$escription A flowerin% plant of Si:erpud Biophytum sensitivum. The 5?wee: old baby mice fo r the plant e9tract testHHHH Plant Material Preparation HHHHHHHHHHHHHH3 (eaf )9tract of the plant, B. sensitivum HHHHHHHHH $i%ital F&SK"&S Tester .itHHHHHHHHHHHHHH3 Preliminary Test Set?UpHHHHHHHHHHHHHHH333 )9perimental $esi%nHHHHHHHHHHHHHHHHH3 Flow of Method involved in the studyHHHHHHHHHH3 Mean $ifference / d0 between initial and final readin% in "&S in Standard -oncentration TestHHHHHH Percenta%e Mean $ifference from Mean $ifference of "&S in Standard -oncentration TestHHHHH33

Pa%e

Graphical presentation of !nitial and Final "&S in the Standard -oncentration of C7%KA77m(HHHHHHHHHH3

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LIST OF APPENDICES

App/n0i1 6 5 C L

D/)2 ip*i+n Statistical AnalysisHHHHHHHHHHHHHH3 TablesHHHHHHHHHHHHHHHHHHH3 Fi%uresHHHHHHHHHHHHHHHHHHH

P3-/

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