DRUGS

INDICATION

ACTION

SIDE EFFECTS

NURSING CONSIDERATION This drug can be taken with or without food For the reason that of a probable intrusion of erdosteine metabolites with the methionine metabolism, erdosteine is no recommended in subjects experiencing hepatic cirrhosis and insufficiency of the cystathionine synthetase enzyme. Ectrin Suspension is also contraindicated for Phenylketonuria, because of existence of aspartame.

Generic Name: Erdosteine Brand Name: Ectrin Classification: Mucolytics

Treatment of acute bronchitis, chronic bronchitis and its exacerbations. Respiratory disorders characterized by abnormal bronchial secretions and impaired mucus transport.

Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.

Sweating Vertigo Flushing

DRUGS Generic Name: Doxofylline Brand Name: Ansimar Classification: Antiasthmatic & COPD

INDICATION Bronchial asthma & pulmonary disease w/ spastic bronchial component.

ACTION Adrenergic bronchodilators and phosphodiesterase inhibitors both work by increasing intracellular level of cyclic-3,5adenosine monophosphate (cAMP); adrenergics by increasing production and phosphodiesterase inhibitors by decreasing breakdown. Increased levels of cAMP produce bronchodilation. Corticosteroids act by decreasing airway inflammation. Anticholinergics (ipratropium) produce brondhodilation by decreasing intracellular levels of cyclic guanosine monophosphate (cGMP).

SIDE EFFECTS Nausea vomiting, epigastric pain cephalalgia irritability insomnia tachycardia extrasystole tachypnea hyperglycemia albuminuria

NURSING CONSIDERATION Assess lung sounds, pulse and blood pressure before administration and during peak of medication. Not amount, color, and character of sputum produced. Monitor pulmonary function tests before initiating therapy and periodically during therapy to determine effectiveness of medication. Observe for paradoxical bronchospasm (wheezing). If conditions occur, withhold medication and notify physician of other health care professional immediately.

DRUGS Generic Name: Citicoline Brand Name: Zynapse Classification: Neurotonics

INDICATION A supplement used to improve thinking, learning, and memory in elderly people.

ACTION For post Cardio Vascular Accident / Stroke. Treatment on elderly, for faster improvement on thinking ability

SIDE EFFECTS SE: Low blood pressure ( faintness, dizziness ), Slow or fast heartbeat, Headache, Nausea and Vomiting or diarrhea AE: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, or rash.

NURSING CONSIDERATION Citicoline may be taken with or without food. Take it with or between meals. The supplement should not be taken in the late afternoon or at night because it can cause difficulty sleeping. Contact the physician immediately if allergic reaction such as hives, rash, or itching, swelling in your face or hands, mouth or throat, chest tightness or trouble breathing are experienced. Citicoline therapy should be started within 24 hours of a stroke. The physician will prescribe the correct dosage and the length of time it should be taken for a medical condition.

DRUGS Generic Name: Ivabradine Brand Name: Coralan Classification: Anti-angina

INDICATION Symptomatic treatment of chronic stable angina pectoris in coronary arterydisease patients w/normal sinus rhythm

ACTION Ivabradine is a pure heart rate-lowering agent, acting by selectiveand specific inhibition of the cardiac pacemaker if current that controls the spontaneousdiastolic depolarisation in the sinus node and regulates heart rate

SIDE EFFECTS bradycardia, palpitations, supra-ventricular extra systoles GI: nausea, constipation

NURSING CONSIDERATION Monitor vital signs. Take the drug as prescribed. Take the tablet on an empty stomach either 30 minutes before or 1-2 hours after meal

DRUGS Generic Name: Cefixime Brand Name: Tergecef Classification: Antibacterial

INDICATION Bronchitis,bronchiectasis withinfection, secondaryinfections of chronicrespiratory tractdiseases, pneumonia,otitis media, sinusitis.Pyelonephritis, cystitis,gonococcal urethritis,cholecystitis. Scarletfever.

ACTION Inhibits bacterial cell wallsynthesis, rendering cellwall osmotically unstable,leading to cell death.

SIDE EFFECTS Hypersensitivity. History of shock due toany ingredient of thisproduct.

NURSING CONSIDERATION Assess patientsprevious reaction topenicillin or other cephalosporins.Crosssensitivitybetween penicillinand cephalosporinsis common. Assess patient for signs and symptomsof infection beforeand duringtreatment; fever,earache,characteristics of wounds, sputum,urine, stool Obtain C&Sbefore beginningdrug therapy toidentify if correcttreatment has beeninitiated Assess for allergicreactions

DRUGS Generic Name: Clopidogrel Brand Name: Plavix Classification: Anti-platelet

INDICATION Treatment of patient at risk for ischemia events such as recent MI, recent ischemia CVA. Treatment of patient with acute coronary syndrome.

ACTION Inhibits platelet aggregation by blocking ADP receptors on platelets, preventing clumping of platelets

SIDE EFFECTS SE: dizziness, lightheadedness , headache, nausea, gastric distress, prolong bleeding AE: skin rash, chest pain, fainting, severe headache, abnormal bleeding.

NURSING CONSIDERATION Lie down in a cool environment and rest. Eat frequent small meals. Alert dentist and health care providers. History: allergy to clopidogel, recent surgery, hepatic impairment

DRUGS Generic Name: Amlodipine Brand Name: Norvasc Classification: Calcium Channel Blocker

INDICATION Angina pectoris due to coronary artery spasm Chronic stable angina, alone or in combination with other agents

ACTION Inhibits the movement of calcium ions across the membranes of cardiac and arterial muscle cells; inhibits trans membrane calcium flow, which results in the depression of impulse formation.

SIDE EFFECTS CNS:Dizziness, lightheadedness, headache,asth enia, fatigue, lethargy CV: Peripheral edema, arrhythmias

NURSING CONSIDERATION Monitor BP for therapeutic effectiveness. BP reduction is greatest after peak levels of amlodipine are achieved 69 h following oral doses. Monitor for S&S of dose-related peripheral or facial edema that may not be accompanied by weight gain; rarely, severe edema may cause discontinuation of drug. Monitor BP with postural changes. Report postural hypotension. Monitor more frequently when additional antihypertensives or diuretics are added.