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December 8th, 2013
To provide a resource for evidence-based Emergency Medical education, this list of must-read landmark articles was created to supplement the Emergency Medicine (EM) internship year of training. There are 52 articles so that one article can be read at leisure each week of the year. I searched national databases and polled faculty at the University of Washington to identify articles that faculty would expect any EM resident to be familiar with or that they felt were practicechanging in EM. Articles were selected for the final list based on the quality of study design, sample size, and relevance for EM residents. Feel free to also download a free PDF of this list. Show 100 System entries Authors Search: Title Journal
FR EE P V C A RD S
Airway/ Respiratory
Reed, MJ et al
Can an Airway Assessment Score Predict Difficulty at Intubation in the Emergency Department? Excluding pulmonary embolism at the bedside without diagnostic imaging: Management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer. Incidence and Predictors of Difficult and Impossible Mask Ventilation. Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome. Does End-Tidal Carbon Dioxide Monitoring Detect Respiratory Events Prior to Current Sedation Monitoring
SE A RCH U S ING
Search!
Airway/ Respiratory
Wells, PS et al
2001
Airway/ Respiratory
Kheterpal, S et al
Anesthesiology
Airway/ Respiratory
2000
Pubmed
Airway/ Respiratory
Burton, JH et al
2006
Pubmed
Shock Index: A Predictor of Morbidity and Mortality? ALiEM Journal Club Question 1: Bias
Practices? Airway/ Respiratory Brochard, L et al Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. Preoxygenation and prevention of desaturation during emergency airway management. Routine vs Selective Invasive Strategies in Patients with Acute Coronary Syndromes: A Collaborative MetaAnalysis of Randomized Trials. Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block. Risk for Clinical Thromboembolism Associated with Conversion to Sinus Rhythm in Patients with Atrial Fibrillation Lasting New England Journal of Medicine 1995 Pubmed Metabolized by the Liver
Thyroid Storm: Treatment Strategies All Benzodiazepines are
Airway/ Respiratory
Kline, JA et al
2008
Pubmed
Airway/ Respiratory
Weingart, SD et al
Cardiology
Mehta, S et al
Cardiology
Sgarbossa, E et al
Email 1996
Pubmed
Subscribe!
Cardiology
Weigner, M et al
1997
Pubmed
Less than 48 Hours. Cardiology Than, M et al 2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker: The ADAPT Trial. Prospective validation of the San Francisco Syncope Rule to predict patients with serious outcomes. A Comparison of Vasopressin and Epinephrine for Out-of-Hospital Cardiopulmonary Resuscitation. Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest. A comparison of rate control and rhythm control in patients with atrial fibrillation. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. Nasogastric Journal of the American College of Cardiology 2012 Pubmed
Cardiology
Quinn, J et al
2006
Pubmed
Cardiology
Wenzel, V et al
2004
Pubmed
Cardiology
2002
Pubmed
Cardiology
Wyse, DG et al
2002
Pubmed
Cardiology
Andersen, HR et al
2003
Pubmed
Gastrointestinal
Palamidessi,
Academic
2010
Pubmed
N et al
aspiration and lavage in emergency department patients with hematochezia or melena without hematemesis. Transfusion strategies for acute upper gastrointestinal bleeding. Omeprazole Before Endoscopy in Patients with Gastrointestinal Bleeding. Improved Outcomes in Patients with Acute Allergic Syndromes Who are Treated with Combined H1 and H2 Antagonists. The risk of catheterrelated bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: A systematic review of the literature and meta-analysis. Antibiotic prophylaxis for mammalian bites.
Emergency Medicine
Gastrointestinal
Villanueva, C et al
2013
Pubmed
Gastrointestinal
Lau, J et al
2007
Pubmed
Immunology
Lin, R et al
2000
Pubmed
Infectious disease
Marik, PE et al
2012
Pubmed
Infectious disease
2001
Pubmed
Infectious
Wong, C et al
The LRINEC
2004
Pubmed
disease
(Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Stiell, IG et al Decision Rules for the Use of Radiography in Acute Ankle Injuries. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Worst Headache and Subarachinoid Hemorrhage: Prospective, Modern Computed Tomography and Spinal Fluid Analysis.
Medicine
Musculoskeletal
1993
Pubmed
Neuroscience
Anderson, CS et al
2008
Pubmed
Neuroscience
Perry, JJ et al
2010
Pubmed
Neuroscience
Johnston, SC et al
Lancet
2007
Pubmed
Neuroscience
Morgenstern, L et al
1998
Pubmed
Neuroscience
The National Institute of Neurological Disorders and Stroke rtPA Stroke Study Group.
1995
Pubmed
Neuroscience
Hacke, W et al
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. Validation of a Prediction Rule for the Identification of Children With Intraabdominal Injuries After Blunt Torso Trauma. Identification of children at very low risk of clinicallyimportant brain injuries after head trauma: a prospective cohort study. Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma. A Prospective Study of Recurrent Febrile Seizures. Relationship of spontaneous
2008
Pubmed
Pediatrics
Holmes, J et al
2009
Pubmed
Pediatrics
Kuppermann, N et al
Lancet
2009
Pubmed
Pediatrics
Altamimi, S et al
2006
Pubmed
Pediatrics
Berg, AT et al
1992
Pubmed
Renal/ urology
Coll, DM et al
2002
Pubmed
passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT. Renal/ urology Luchs, JS et al Utility of hematuria testing in patients with suspected renal colic: correlation with unenhanced helical CT results. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock. Early goal-directed therapy in the treatment of severe sepsis and septic shock. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. Selective cervical spine radiography in blunt trauma: methodology of the National Emergency X-Radiography Utilization Study (NEXUS).
Roentgenology
Urology
2002
Pubmed
Resuscitation
Dellinger, RP et al
2013
Pubmed
Resuscitation
Rivers, E et al
2001
Pubmed
Resuscitation
Jones, AE et al
2010
Pubmed
Trauma
Hoffman, JR et al
1998
Pubmed
Trauma
Bickell, WH et al
Immediate Versus Delayed Fluid Resuscitation for Hypotensive Patients with Penetrating Torso Injuries. The Canadian CSpine Rule for Radiography in Alert and Stable Trauma Patients. The Canadian CT Head Rule for patients with minor head injury. Prehospital Hypoxia Affects Outcome in Patients with Traumatic Brain Injury: A Prospective Multicenter Study. Indications for Computed Tomography in Patients with Minor Head Injury. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
1994
Pubmed
Trauma
Stiell, IG et al
2001
Pubmed
Trauma
Stiell, IG et al
Lancet
2001
Pubmed
Trauma
Chi, JH et al
Journal of Trauma
2006
Pubmed
Trauma
Haydel, MJ et al
2000
Pubmed
Trauma
Lancet
2010
Pubmed
Trauma
Branney, SW et al
Critical Analysis of Two Decades of Experience with Postinjury Emergency Department Thoracotomy in a Regional Trauma Center. Effects of the Second National Acute Spinal Cord Injury Study of HighDose Methylprednisolone Therapy on Acute Cervical Spinal Cord Injury-Results in Spinal Injuries Center. A national evaluation of the effect of traumacenter care on mortality. Quantitative Sensitivity of Ultrasound in Detecting Free Intraperitoneal Fluid. Emergency department bedside ultrasonographic measurement of the caval index for noninvasive determination of low central venous pressure.
Journal of Trauma
1998
Pubmed
Trauma
Tsutsumi, S et al
Spine
2006
Pubmed
Trauma
MacKenzie, EJ et al
2006
Pubmed
Ultrasound
Branney, SW et al
Journal of Trauma
1995
Pubmed
Ultrasound
Nagdev, AD et al
2010
Pubmed
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Emily: Thanks for compiling a list of ground breaking articles. Did you know about the Best Evidence in Emergency Medicine (BEEM) www.BEEMSite.com BEEM has the only validated audience rating tool in emergency medicine continuing medical education. Worster et al. Consensus Conference Follow-up: Inter-rater Reliability Assessment of the Best Evidence in Emergency Medicine (BEEM) Rater Scale, a Medical Literature Rating Tool for Emergency Physicians. Acad Emerg Med Nov 2011. The BEEM rater score, to the best of our knowledge, is the only known measure of clinical relevance. It has a high interrater reliability and face validity and correlates with future citations. Carpenter et al. Best Evidence in Emergency Medicine (BEEM) Rater Scores Correlate With Publications Future Citations. Acad Emerg Med Oct 2013. Go to http://thesgem.com/beem/ to find out more. I am going to look through our database from 2005-2013 to see how many papers we have both covered. Good job, big effort, keep up the good work. Ken Milne
Ken Milne
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Mat t A s t in
a month ago
Emily, Thanks to you and your colleagues for putting together this list. I know it was hard to pare it down to just 52. Hopefully, someone will continue this list and update it when new landmark articles are published. Great job.
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E mily
Dr Astin, Thanks for your post. It was hard to pare it down to 52! I'm planning on maintaining this list for the next several years to keep it up to date and reflective of new literature, and then setting up a sustainable way for the list to be maintained by other UW residents. Thanks for the nice comments, Emily
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Dan
a month ago
We'll keep a list over at WikEM: http://www.wikem.org/wiki/WikE... where you can keep tack of your notes to ensure long term learning.
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E mily
Great resource! I'll try to add some more articles to the list! Emily
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Niles h P at el
a month ago
A B OU T This blog aims to disrupt how medical providers and trainees can gain public access to high-quality, educational content while also engaging in a dialogue about bestpractices in Emergency Medicine and medical education. We strive to reshape medical education and academia in their evolution beyond the traditional classroom. EM : RA P PO D CA ST Dr. Michelle Lin is on the EM:RAP podcast team reviewing high-yield ALiEM blog content.
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