Definition
Chronic condition characterized by widespread pain that covers half the body and has lasted for 3 months.
Anatomy
Prevalence ranging 2% to 12% in the general population and primarily involving in mddle aged women
Pathophysiology
With intense or prolonged exposure to painful stimuli, incoming afferent signals are increased, and presynaptic release of substance P and EAAs is enhanced. An influx of Ca2+ increases the production of nitric oxide, which diffuses out of the PTN and causes the PTN to become hyperexcitable and further enhances the presynaptic release of EAAs and substance P..
Clinical Manifestation
11 out of 18 tender points Sleep disturbances Fatigue, stifness, (associated) Psycological aspect (anxiety)
Suboccipital muscle insertion at base of skull; anterior aspect of intertransverse process spaces at C57; midpoint of upper border of trapezius muscle; Above scapular spine near medial border of scapula; second costochondral junction; lateral epicondyle; upper outer quadrant of buttocks; Posterior aspect of trochanteric prominence; medial fat pad of knee
Complications
Sleeping disturbance Posture Anxiety
AEROBIC EXERCISE
Fibromyalgia: TREATMENT
Patients should be informed that they have a condition that is not crippling, deforming, or degenerative, and that treatment is available IMPROVE SLEEP: NSAIDs and corticosteroids Combination therapy Biofeedback, tender point injection Acupuncture, aerobic exercise