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Comparison chart between osteoarthritis and RA

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Osteoarthritis
Systemic symptoms are not present. Localized joint pain (Knee and hips) but NO swelling Pain severity is important (mechanical, inflammatory, noctornal, sudden)

Rheumatoid Arthritis
Dull pain and inflammation Frequent fatigue (afternoon), stiffness, ulnardeviation, muscle atrophy, swelling of the knuckles , synovial Thickness complications: joint fail, depression, Osteoporosis, infections surgical complications Frequent feelings of "being sick inside," with fevers, weight loss, or involvement of other organ systems.carpal tunnel Extra-articular manifestations: nodules, vasculitis, pulmonary, cardiac, skin (vasculitis), eye (sjorgen's syndrome, scleritis chronic Autoimmune

Presence of symptoms affecting the whole body (systemic):

Associated symptoms:

(no systemic symps) fatigue,muscle weakness, fever, organ involvement; Bony enlargement, deformity, instability, restricted movement, joint locked, sleep dist,depression, comorbid conditions (bursitis, fibromyalgia, gout) Normal wear and tear (chronic degenerative) NSAIDs (short term use) Acetaminophen, Analgesics, exersise

Disease Process:

Treatment:

NSAIDs, Steroids (Prednisone), DMARDs (Methotrexate), Antimalarial (Plaquenil), Corticosteriods, Affects more women than men

Gender:

Common in both men and women. Before 50 more men than women, after 50 more women than men local inflammation/effusion sometimes x-ray, pain assessment- perarticular and articular source of pain, presence of deformity, evidence ofmuscle wasting, local inflammation. asymmetrical joints Herberden's & Bouchard's nodes

Effusions:

Common

Diagnosis:

1- Anemia (ferratin, ion. ion binding capacity) 2- bone (inc ALP) 3Inflammatory markers (C reactive protein and ESR)

Nodules:

Present, especially on extensor surfaces. Swan neck deformity. Biopsy important to eliminate gouty tophi

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Osteoarthritis
Asymmetrical & may spread to the other side. Symptoms begin gradually and are often limited to one set of joints, usually the finger joints closest to the fingernails or the thumbs, large weight-bearing joints, Over 60 Less severe Slow, over years wear and tear associated w/ aging or injury, also caused by injuries to the joints, obesity, heredity, overuse of the joints from sports Joints painful but without swelling; affects joints asymmetrically; affects bigger joints such as hips & knees. Localized with variable, progressive course movement increases pain One or several joints; enlarged, cool, and hard on palpation;

Rheumatoid Arthritis
Symmetrical - often affects small and large joints on both sides of the body, such as both hands, both wrists or elbows, or the balls of both feet,

Pattern of joints that are affected:

Age of onset: Severity: Speed of onset: Cause:

35-45 years old More severe Rapid, within a year Classified as an autoimmune disease, No real known cause.-Connection between environmental and genetic factors;female reproductive hormones Joints are painful, swollen, and stiff; affects joints symmetrically; affects smaller joints such as hands & ankles. Systemic with exacerbations and remissions movement decreases pain Joints are swollen, red, warm, tender, and painful;several joints involved; Extraarticular: Rheumatoid nodules, Sjogrens sydrome, Felty syndrome Bony erosions, soft tissue swelling, angular deformities,

Joint symptoms:

pain w/ movement: Assessment:

Radiologic findings:

Loss of joint space and articular cartilage, routine wear and tear osteophytes, sclerosis, cysts, loose bodies, alignment Rheumatoid Factors (RF) negative, transient elevation in ESR related to synovitis Family HX of OA-womenm

Lab findings:

RF positive, increased ESR & CRP, antinuclear antibody, arthrocentesis

Genetic Factors:

RA and Leukocyte antigen- female reproductive hormones, Epstein-Barr virus

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Osteoarthritis
collaborate with PT to provide heat or cool packs, positioning, and mobility, Keep weight within normal limits, assist with smoking cessation, avoid risk taking activities, avoid or limit participation in recreational sports, wear supportive shoes, do not perform repetitive exercises,

Rheumatoid Arthritis
Helps control the diseas and decrease intensity and number of exacerbations Healthy nutrition, report ASE from medication use, teach that RA is systemic and effects many body systems,

Interdisciplinary Team: Patient Education:

Cause Rheumatoid arthritis (RA) is a disease in which your own immune system mistakenly attacks healthy tissue, causing inflammation that damages your joints. No single cause for RA has been found; current theory suggests patients are genetically predisposed to the disease. On the other hand, Osteoarthritis (OA) is not an autoimmune disease. It is a condition of wear and tear associated with aging or injury. The immune system is not affected. Common causes for OA include joint injury, repetitive strain/use, being overweight as well as genetic predisposition. EDITSigns and symptoms

RA usually causes pain or stiffness lasting for more than 30 minutes in the morning or after long rest and lack of activity. OA stiffness tends to get worse with use throughout the day. RA is associated with symmetrical swelling e.g., both hands, both elbows, etc. whereas OA is associated with asymmetrical (not "matching") swelling in individual joints that are not part of a pair e.g., one knee and an elbow, instead of both knees Most typically, RA symptoms include joint pain, swelling, tenderness, and redness of the joints; prolonged morning stiffness; and less range of movement. Some people also experience fever, weight loss, fatigue, and/or anemia Generally, OA symptoms include joint stiffness, pain, and enlarged joints and it does not have any systemic symptoms. RA tends to cause swelling and pain in smaller joints such as the hands and ankles while OA tends to cause pain and swelling in bigger joints such as the hips and knees.

EDITLocation of joints involved With RA, inflammation generally occurs in the knuckles and at the joints closest to your hands, nearer the base of your fingers. On the other hand with OA, inflammation generally occurs at the joint closest to your fingernail. EDITPrevalence

OA is much more common than RA. In the United States alone, an estimated 20 million people have osteoarthritis, and approximately 2.1 million people have RA.

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