Department of Pharmaceutical Chemistry

Biochemistry Practical (PHARM-113), Pharm.D Program-2014

Course Incharge: Ahsaan Ahmed

EXP.#
01 02

EXPERIMENT TOPICS
Introduction to Biochemistry Lab Qualitative Detection of Carbohydrate (Scheme) Detection of Monosaccharides:

LABS
01 01

03 04 05

a) Glucose b) Galactose c) Fructose Detection of Disaccharides: 06

05 06 07

a) Maltose b) Sucrose c) Lactose Detection of Polysaccharides:

08 08

a) Starch b) Glycogen c) Dextrin

09 10 11 12 13 14 15 16 17

Formation of Osazone Quantitative Estimation Casein estimation from Milk Albumin Peptone Gelatin Acid number fats Saponification Urine Analysis CSF

01 06

01 01

Department of Pharmaceutical Chemistry

Biochemistry Theory (PHARM-111), Pharm.D Program-2014

Course Incharge: Ahsaan Ahmed / Sobia Mastoor

No
1 1.1

TOPICS
GENERAL INTRODUCTION AND BASIC BIOCHEMICAL PRINCIPLES: Role of Pharmaceutical Biochemistry in the health profession. Nature of biochemical reactions.

LECTURES

04

2 2.1

BASIC CHEMISTRY OF BIOMOLECULES: (Nature, Classification etc.) Carbohydrates: Chemistry, Classification, Reactions of Carbohydrates, Optical activity, Biological and pharmaceutical importance of carbohydrates.

-07

2.2

Lipids: Chemistry of Fatty acids and Lipids, Classification (Saponifiable and non-saponifiable lipids, Simple, Complex and Derived lipids), Reactions of Fatty acids and other Lipids, Essential fatty acids, Biological and pharmaceutical importance of lipids.

05

2.3

Vitamins: Chemistry, Classification (Fat-soluble and water-soluble vitamins), Biological and pharmaceutical importance of vitamins.

06

Department of Pharmaceutical Chemistry

Medicinal Chemistry Theory (PHC-601), Pharm.D Program-2014

Course Incharge: Ahsaan Ahmed

No 1 1.1 1.1.1 1.2 1.2.1 TOPICS Introduction to Medicinal Chemistry Course Outline Defination Objective of Medicinal Chemistry Chemical Constitution Structural Features Stereochemistry and biological activity Forces involved in drug receptor interaction Receptor theories ADME Metabolism of Drug a. Introduction b. Enzymes involved in the process c. Reaction involved in Metabolism I)Phase-I transformation ii)Phase-II transformation S.A.R Classification of Synthetic Drugs Synthesis Mechanism and reactions Drug designing and recent approaches Computational Chemistry (CAD, LBDD, SBDD) General Properties, Chemistry (General methods of determination, the structure & isolation from natural source), Biological Action, Structure Activity Relationship And Therapeutic Applications Of The Following: a) Alicyclic Compounds: Cyclopropane, Terpenes, Citral, Pinene, Camphor, Menthol, Carotenes. b) Alkaloids: Atropine, Morphine and related compounds (Codeine, Thebaine), Ergotamine, Reserpine, Ephedrine. c) Vitamins: Water Soluble Vitamins (B1, B2, B6, B12, Folic acid, Nicotinic acid, Biotin, Pantothenic acid and Ascorbic acid) Fat Soluble Vitamins (A, D, E, and K). d) Hormones: Steroidal Hormones (Testosterone, Progesterone, Estrogen, Aldosteron and Cortisol), Proteinous Hormones (Insulin, Glucagon, Oxytocin and Vassopressin). LECTURES 20

1.2.2 1.3 1.4 1.4.1 1.4.2 1.4.3

1.5 2 2.1 2.2 2.2.1 3

09

15

3.1 3.2 3.3

3.4