Generic name 1.Celecoxib Classification :NSAID, Analgesic (nonopioid), Specific COX-2 enzyme bloc e! Dosage: 2"" mg re!

uenc": #ID p!n fo pain #oute: O!al

Brand Name Celeb!ex

Mechanism of Action Celecoxib $as COX-2 specific in$ibi%o!y ac%i&i%y' I% in$ibi%s %$e con&e!sion of a!ac$idonic acid %o p!os%aglandins ($ile $a&ing no effec% on %$e fo!ma%ion of p!os%aglandins %$a% media%e %$e no!mal $omeos%asis in %$e )I %!ac%, idneys and pla%ele%s ca%alyzed by COX-*'

Indications Ac+%e and long-%e!m %!ea%men% of signs and symp%oms of !$e+ma%oid a!%$!i%is and os%eoa!%$!i%is ,ed+c%ion of %$e n+mbe! of colo!ec%al polyps in familial adenoma%o+s polyposis (-A.) /anagemen% of ac+%e pain

Contra-indications 0ype!sensi%i&i%y incl+ding %$ose in ($om a%%ac s of angioedema, !$ini%is and +!%ica!ia $a&e been p!ecipi%a%ed by aspi!in, NSAIDs o! s+lfonamides' Se&e!e $epa%ic impai!men%1 se&e!e $ea!% fail+!e1 inflamma%o!y bo(el disease1 pep%ic +lce!1 !enal impai!men% (C!Cl 23" ml4min)1 p!egnancy and lac%a%ion'

Adverse Effects Abdominal pain Dia!!$ea Na+sea 5dema Dizziness 0eadac$e Insomnia +ppe! !espi!a%o!y %!ac% infec%ions !as$ .o%en%ially -a%al6 exfolia%i&e de!ma%i%is S%e&ens-7o$nson synd!om %oxic epide!mal nec!olysis'

Nursing Consideration *' Info!m %$e pa%ien% %o %a e d!+g (i%$ food o! meals if )I +pse% occ+!s' 2' Info!m %$e pa%ien% %o %a e only %$e p!esc!ibed dosage1 do no% inc!ease dosage' 3' Info!m %$e pa%ien% %$a% $e4s$e may expe!ience %$ese side effec%s6 Dizziness, d!o(siness (a&oid d!i&ing o! %$e +se of dange!o+s mac$ine!y ($ile %a ing %$is d!+g)' 8' Info!m %$e pa%ien% %o !epo!% so!e %$!oa%, fe&e!, !as$, i%c$ing, (eig$% gain, s(elling in an les o! finge!s1 c$anges in &ision'

Generic Name $.Cef+!oxime Axe%il

Brand Name Cef+!oxime Axe%il (Cef%in Classification: @.'O'A) Anti-infective Dosage: 9:" mg re!uenc": ;<= #oute: I> ANS?

Mechanism of Action Secondgene!a%ion cep$alospo!in %$a% in$ibi%s cell-(all syn%$esis, p!omo%ing osmo%ic ins%abili%y1 +s+ally bac%e!icidal'

Indications .$a!yngi%is, %onsilli%is, infec%ions of %$e +!ina!y and lo(e! !espi!a%o!y %!ac%s, and s in and s ins%!+c%+!e infec%ions Bncomplica%ed B?Is C O%i%is /edia C .$a!yngi%is and ?onsilli%is C 5a!ly Dyme Disease C Seconda!y bac%e!ial infec%ion of ac+%e b!onc$i%is C Bncomplica%ed gono!!$ea'

Contraindications C Con%!aindica%ed in pa%ien%s $ype!sensi%i&e %o d!+g' C Bse ca+%io+sly in pa%ien%s $ype!sensi%i&e %o penicillin beca+se of possibili%y of c!osssensi%i&i%y (i%$ o%$e! be%a-lac%am an%ibio%ics' C Bse (i%$ ca+%ion in b!eas%-feeding (omen and in pa%ien%s (i%$ $is%o!y of coli%is o! !enal s+fficiency'

Adverse Effects C>6 p$lebi%is, %$!ombop$lebi%is )I6 pse+domemb!ano+s coli%is, na+sea, ano!exia, &omi%ing, dia!!$ea 0ema%ologic6 %!ansien% ne+%!openia, eosinop$ilia, $emoly%ic anemia, ?$!ombocy%openia S in6 mac+lopap+la! and e!y%$ema%o+s !as$es, +!%ica!ia, pain, ind+!a%ion, s%e!ile abscesses, %empe!a%+!e ele&a%ion' O%$e!6 $ype!sensi%i&i%y !eac%ions, se!+m sic ness, anap$ylaxis'

Nursing Consideration 2' #efo!e adminis%e!ing, ma e s+!e pa%ien% is no% alle!gic %o penicillins o! cep$alospo!ins' 3' Abso!p%ion of cef+!oxime axe%il is en$anced by food' 8' Cef+!oxime axe%il %able%s may be c!+s$ed if s(allo(ing is a diffic+l%y' :' ?a e medica%ion as p!esc!ibed, e&en af%e! feeling be%%e!' E' ?a e o!al fo!m (i%$ food' 9' If s+spension is being +sed, s$a e %$e con%aine! (ell befo!e meas+!ing dose' <' No%ify p!esc!ibe! abo+% !as$es o! s+pe! infec%ions'

Generic Name %..A,AC5 ?A/OD Classificati on: An%ipy!e%ic4Anal gesic orm: ?able%s Dosage: :"" mg re!uenc": F 8 4 .,N #oute: O!al

Brand Name #iogesic

Mechanism of Action ?$o+g$% %o p!od+ce analgesia by bloc ing pain imp+lses by in$ibi%ing syn%$esis of p!os%aglandin in %$e CNS o! of o%$e! s+bs%ances %$a% sensi%ize pain !ecep%o!s %o s%im+la%ion' ?$e d!+g may !elie&e fe&e! %$!o+g$ cen%!al ac%ion in %$e $ypo%$alamic $ea%-!eg+la%ing cen%e!'

Indication G/ild pain o! -e&e!

Contraindications GCon%!aindica%ed in pa%ien% $ype!sensi%i&e %o d!+g' GBse ca+%io+sly in pa%ien% (i%$ long %e!m alco$ol +se beca+se %$e!ape+%ic doses ca+se $apa%o%oxici%y in %$is pa%ien%s'

Adverse Effects G0ema%ologic6 $emoly%ic anemia, ne+%!openia, le+copenia, pancy%openia' G0epa%ic6 Ha+ndice G/e%abolic6 $ypoglycemia GS in6 !as$, +!%ica!ia'

Nursing Consideration *' Ad&ise pa%ien% %$a% d!+g is only fo! s$o!% %e!m +se and %o cons+l% p!esc!ibe! if gi&ing %o c$ild!en fo! longe! %$an fi&e days o! ad+l% fo! longe! %$an %en days' 2' ?ell pa%ien% no% %o +se fo! ma! ed fe&e!( %empe!a%+!e $ig$e! %$an *"3'* - @3I': CA), fe&e! pe!sis%ing longe! %$an %$!ee days, o! !ec+!!en% fe&e! +nless di!ec%ed by p!esc!ibe!' 3' Ale!%6 Ja!n pa%ien% %$a% $ig$ doses o! +ns+pe!&ised long %e!m +se can ca+se li&e! damage' 8' ?ell %o b!eas% feeding (oman %$a% ace%aminop$en appea!s in b!eas% mil lo( le&els ( less %$an *K dose)' D!+g may be +sed safely if %$e!apy is s$o!% %e!m and doesnL% exceed !ecommended doses'

Generic Name &. 5!dos%ein Classificati on: m+coly%ic agen% orm: Caps+le Dosage: 3"" mg re!uenc": #ID #oute: O!al

Brand Name Me!%in

Mechanism of Action Ac%s as a p!od!+g and i%s me%aboli%es a!e mainly !esponsible fo! m+coly%ic ac%i&i%y' I% (o! s by $elping %o b!ea do(n m+c+s sec!e%ions'

Indication ?!ea%men% of ac+%e and c$!onic b!onc$o p+lmona!y disease

Contraindications Con%!aindica%ed in pa%ien%s (i%$ pep%ic +lce!, .!egnancy and $ype!sensi%i&i%y'

Adverse Effects S%omac$ pain Na+sea >omi%ing loose s%ools spasmodic coli%is $eadac$e'

Nursing Consideration *' #efo!e gi&ing %$e medica%ion ma e s+!e %$a% %$e clien% is no% p!egnan% and non lac%a%ing' 2' Info!m %$e pa%ien% %$a% i% can be %a en (i%$ o! (i%$o+% food' 3' As %$e pa%ien% %o no%ify any of %$e $eal%$ca!e %eam if %$e $e feels na+sea, &omi%ing, abdominal pain o! %a!!y s%ools occ+!' 8' 5mp$asize %$e impo!%ance follo( +p exams

Generic Name '..!ednisone

Classificatio n: Co!%icos%e !oid (in%e!media%e ac%ing), )l+coco!%icoi d, 0o!mone

Brand Name
Del%asone

Mechanism of Action
I% dec!eases inflamma%ion by s+pp!ession of mig!a%ion of polymo!p$on+clea ! le+ ocy%es and !e&e!sal of inc!eased capilla!y pe!meabili%y1 s+pp!esses %$e imm+ne sys%em by !ed+cing ac%i&i%y and &ol of %$e lymp$a%ic sys%em1 s+pp!esses ad!enal f+nc%ion a% $ig$ doses' Indica%ions and dosage a!e same as %$ose fo! p!ednisolone'

Indication
S$o!%-%e!m managemen% of &a!io+s inflamma%o!y and alle!gic diso!de!s, s+c$ as !$e+ma%oid a!%$!i%is, collagen diseases (eg, SD5), de!ma%ologic diseases (eg, pemp$ig+s), s%a%+s as%$ma%ic+s, and a+%oimm+ne diso!de!s' ,eplacemen% %$e!apy in ad!enal co!%ical ins+fficiency

Contraindications
0ype!sensi%i&i%y, se!io+s infec%ions (excep% %+be!c+lo+s meningi%is), &a!icella, sys%emic f+ngal infec%ions'

Adverse Effects
Insomnia, ne!&o+sness, inc!eased appe%i%e, indiges%ion, dizziness4lig$%$eaded ness, $eadac$e, $i!s+%ism, $ypopigmen%a%ion, diabe%es melli%+s, gl+cose in%ole!ance, $ype!glycaemia, a!%$!algia, ca%a!ac%s, gla+coma, epis%axis, diap$o!esis, C+s$ingNs synd!ome, edema, f!ac%+!es, $all+cina%ions, $ype!%ension, m+scle(as%ing, os%eopo!osis, panc!ea%i%is, pi%+i%a!yad!enal axis s+pp!ession, seiz+!es'

Nursing Consideration *' Info!m %$e p%' %o do no% s%op %a ing %$e d!+g (i%$o+% cons+l%ing yo+! $eal%$ ca!e p!o&ide!1 2' Info!m %$e p%' %o A&oid expos+!e %o infec%ions' 3' Info!m %$e p%' %o ,epo!% +n+s+al (eig$% gain, s(elling of %$e ex%!emi%ies, m+scle (ea ness, blac o! %a!!y s%ools, fe&e!, p!olonged so!e %$!oa%, colds o! o%$e! infec%ions, (o!sening of %$e diso!de! fo! ($ic$ %$e d!+g is being %a en'

orm: ?able% Dosage:

: mg

re!uenc": ?ID #oute: O!al