Debbie Swinarski, BS, LATG Oakland, CA 94618 510.388.7598 deswinarski@gmail.

com

A highly skilled Senior Research Associate with over 10 years of experience in oncology, pharmacology, diabetes and vaccine research. An exceptional surgical and in vivo specialist with excellent leaders hip skills and ability to interact effectively between principal investigat ors, research associates, peers as well as professionals outside the scope of my profession.

Profe ssional Experience: Anacor Pharmaceuticals, Palo Alto, CA 94303 October 2013 present Senior Research Associate lll, Pharmacology Department Performed supportive pharmac ology studies with rodents including handling, dosing; mainly PO and IV, tissue dissection and necropsies. Executed tasks within AALAC compliance that included regulatory oversights with the FDA and the USDA. Oversaw daily operations of the animal facility including procurement and husbandry. Worked with Category B selective agents Epitogene si s, Inc. Walnut Creek, CA 94596 February 2008 October 2013 Senior Research Associate III / Independent contractor Serving as key research associate on independent project foc used on vaccine research including comprehensive aspects of animal handling, injections, nec ropsy and tissue harvesting along with isolation of tissues and lymph nodes. Independently preparing single cell suspension from various lymph nodes and spleen and ex vivo activations. CHORI (Childrens Hospi tal of Oaklan d Research Institute), Oakland, CA 94608 October 2010 December 2012 Staff Research Associate, Diabetes Research Department Performed extensive diabetes research to det ermine the validity of several hypotheses. Analyzed blood and tissue analysis to back up in vivo work. Executed metabolic disease studies consisting of novel surgeries, necropsy and data analysis. Created and maintained 9 mouse strain-breeding colonies. Maintained laboratory notebook with day-to-day data and study progress. Procured supplies and various instruments necessary for res earch. Complied within IACUC guidelines. Genentech, Inc., South San Francisco, CA 94080 October 2009 - May 2010 Associate Project Manager, Translational Oncology Department Managed contract research organizatio ns, evaluated efficacy of anti-cancer agents in xenograft models. Interfaced between Genentech investigators and CROs in the ex perimental design, writing and editing protoc ols, data analysis and communication of study results. Expedited the exchange of drug and study samples, preparation of dosing solutions and database administration. Ensured tracking and reported progress to enable the scientific team at all levels to get a clear picture of project status, upcoming activities and milestones.

Managed the organization and storage of project documents. Tracked and expedited the resolution of action items. Prepared meeting minutes and agendas. Provided support for Translational Oncology and Cancer Signaling team. Proteolix, Inc., South San Francisco, CA 94080 January 2008 - March 2009 Senior Research Associate, Pharmacology Department Developed two mouse models of metastasis evaluating the utility of proteosome inhibitor therapies now adopt ed as a company protocol. Generat ed proof of concept data for target validation in mouse models of metastasis. Designed and reported combination chemotherapy studies (toxicity and efficacy) in murine mouse models. Executed non-clinical pharmacology studies, including range -finding toxicology and anti-tumor activity. Executed rodent (rat & mouse) PK/PD studies for formulation development. E valuated activity of compound in mouse models of inflammatory bowel disease and angiogenesis. Created an IA CUC accredited vivarium in 3 months and $500K under budget. Supervised husbandry staff of 5 for the animal facility. Novarti s Institute for Biomedical Research (formally Chiron), Emery ville, CA 94608 September 1998 -- October 2007 Research Associate II, Pharmacology Department (October 2005 October 2007) Independently maint ained mous e tumor models that support ed multiple drug development projects. Independently executed 5 separate mouse tumor models, including tissue culture, implantation, dosing and data analysis; various histology skills such as wet tissue trimming and paraffin embedding of tissues. Maintained accurate laboratory notebook. Animal Specialist lll, Comparative Medicine ( S eptember 1998 October 2005) Primary surgical specialist and liaison for Pharmacokinetics, Oncology and Toxicology groups. Performed cannulations of rats and mice including jugular, femoral and bile duct that supported PK/PD studies. Performed complete blood count analysis on rodent samples for Pharmacology group. Exceptional proficiency in IP, IV, PO and S C dosing as well as cardiac punctures. Trained new vivarium users and scientific investigators, wrot e SOTs, protocols and amendments. Executed tasks within AALAC compliance that included regulatory oversights with the FDA and the USDA. Oversaw daily operations of the animal facility including procurement and supervising husbandry staff. Established a serology program, handled room logs and maintained compliance for IACUC. Performed supportive pharmac ology studies with rodents including handling, dosing, tissue dissection, novel surgeries including harvesting dorsal root ganglia and necropsies. Presented data at research meetings and monthly departmental meetings. Executed multiple projects in vaccines and independently worked on prion project. Knowledge and experience with ELISA assays, gel electrophoresis and cell extraction. Working knowledge and proficiency in MS Office products and specialty programs such as GraphPad Prism and Study Director for scientific reporting and Alfa Wasserman Diagnostics.

Publications and Education:

CHI R-258 I s Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3 Expressing Orthotopic Multiple Myeloma Model in Mice Clin Cancer Res August 15, 2006 12; 4908 Xiaohua Xin, Tinya Abrams, Paul Hollenbac h, Katherine Rendall, Yan Teng, Yoko Oui, Millicent Embry and Debbie Swinarski Orthotopic Xenograft Model s of Human Multiple Myeloma for Evaluation of Novel Targeted Therapies. AACR Mouse Models of Cancer, 2007, abstract .; Rendahl K, Long L, Patawaran M, Xin X, Gelb A, Garrett E, Zhang W, Oei Y, Swinarski D and Heise C The Orally Bioavailable Proteasome Inhibitor PR-047 Inhibits Meta sta si s in a Mouse Mammary Carcinoma Model; Mol Cancer Ther Dec ember 2009 Jing Jiang, Christopher J. Kirk, Tony Muchamuel, Debbie Swinarski and Mark K. Bennett

AALAS Certified in Microsurgery for Small Animals AALAS Registered LA TG Certified in Blood Testing and Diagnostics from Alfa-Wassermann Doctor of Chiropractic, National College of Chiropractic, Lombard, IL Bachelor of Biological Sciences, DePaul University, Chicago, IL