EVALUATION Distribution of Marks By the end of this course we expect you to be well prepared to do experimental research and for

a practical work term. Therefore evaluation will focus on a number of aspects that we feel are pertinent to such preparation. The scheduled exercises in Part 1 of the course will contribute 60% of the total mark. xamples of all evaluation forms used in Part 1 of the course are printed in the course manual. The !esearch Pro"ect in Part # will contribute $0% of the total mark. Contribution to final course mark %aboratory Performance #0% Part 1 %aboratory !eports &0% %earnin' (b"ectives 10% )upervisor*s !eport 10% Project !esearch Pro"ect Presentation 10% Part !esearch Pro"ect !eport #0% Laborator! Performance + ,ccurate and reliable manipulation of e-uipment. + ,bility to identify and solve problems. + .ritical analysis and ability to think. + Participation in cleanin' up at the end of each lab. + Preparation for experiment. + )harin' of workload between 'roup members /without domination0. + ,cceptance of assistance1 information or su''estions. Laborator! "e#orts %earnin' how to write a proper report of the experiments you perform will be a ma"or achievement for you durin' this course. 2our reports must demonstrate that you have attained the stated aims of the experiment. 2our understanding should be sufficient to explain what you did1 what you observed1 what method of analysis you chose to use etc1 nothin' more. !eports may be hand+written and should be in the format of a scientific paper with the followin' sections3 1. Intro$uction% This section should briefly and clearly state the ob"ectives of the work and approaches used. 4eep this section limited to about one half pa'e. #. Materials an$ Met&o$s% )ince most of the content of this section is 'iven in the lab manual1 this section should be fairly short. !efer to the instructions in the lab manual and indicate anythin' that you may have done differently. !emember that methods of data analysis are methods. 5n most of these exercises you are left to decide for yourself how to analyse your data. Therefore you must include this information here. &. "esults% This section should present the information obtained in the course of your work as clearly and concisely as possible. ,lways provide a well annotated sample tracin' of1 for example1 a chromato'ram or an action potential to illustrate salient points that you will refer to. 6se 'raphs and tables1 embed them in the text as close as possible to the point at which they are first mentioned. $. Discussion% This is the section in which you interpret your results and put them into a 'eneral context. .omment on the de'ree to which your results a'ree or differ from what is in the literature or your hypothesis. 7or unsuccessful experiments1 analy8e the reasons for the lack of success and su''est improvements. .omment on shortcomin's of the techni-ue that you used. 9. "eferences% 5nformation taken from previously published work should be acknowled'ed with a reference. !eferences should be cited in the text and listed at the end of your report usin' exactly the style as that employed in the British :ournal of Pharmacolo'y . 6. A##en$i'% ,ppendices are not necessary and are rarely found in the pharmacolo'ical literature except to show the derivation of e-uations used. 5f you have additional material that you would like to keep to'ether then you can place it in an appendix. But remember that the body of the text should be fully comprehensible without reference to the appendix.

4ey words to remember when writin' your report are clear1 concise and critical. ,lthou'h you must work to'ether to analy8e your data1 you must submit individual reports. !eports are due two weeks after the completion of each three weeks exercise. , deduction of 19% per workin' day will be made on late reports. Learnin( Objecti)es ach individual exercise is accompanied by a set of %earnin' (b"ectives1 these represent concepts that you are expected to understand as a result of workin' on and thinkin' about each exercise. 2ou must provide a list of leanin' ob"ectives for each exercise1 alon' with a brief /usually no more than three sentences0 description of your understandin' of each ob"ective. ;o this even thou'h you may have discussed the ob"ective in your %aboratory !eport. *elf+e)aluation of *kills Objecti)es By the end of Part 1 of &B06 you should have mastered the followin' skills sufficiently as to be able to perform them without help from another individual. 2ou will evaluate your own attainment of these ob"ectives. 1. Be able to make up Physiolo'ical )alt )olution #. <iven the solubility and molecular wei'ht1 be able to make up any feasible molar concentration of a compound and serial dilutions &. Be able to operate automatic pipettes to their maximum accuracy $. Be able to set+up the Grass Polygraph for isometric recordin' 9. Be able to set+up the Brandel Cell Harvester for analysis of li'and bindin' 6. Be able to prepare tritiated samples for li-uid scintillation countin' =. Be able to operate the LSC-3801 li-uid scintillation counter and interpret the print+out >. Be able to set+up the colourimetric assay for determination of ), ?. Be able to make patch pipettes usin' the Sutter P-8 Pipette Puller 10. Be sufficiently familiar with Pulse software to write and store functional Pulse Generator files. *u#er)isor,s "e#ort ,t the end of the !esearch Pro"ect component / Part # 0 of &B061 your supervisor will evaluaute your performance usin' exactly the same criteria as for %aboratory Performance above. "esearc& Project Presentation The -uality of your 'roup*s !esearch Pro"ect Presentation will be assessed accordin' to the followin' criteria1 with individual points havin' the same wei'ht3 Intro$uction 1. The students 'ave a succinct outline of the proposed study #. The ob"ectives of the study and hypothesis to be tested were clearly stated &. The students explained clearly why the particular experimental approach was taken Met&o$s 1. The students demonstrated an understandin' of the conceptual basis of the experimental approaches used #. The students demonstrated an understandin' of the stren'ths and weaknesses of the experimental approach used "esults 1. The results were presented clearly with important issues hi'hli'hted #. The students demonstrated an understandin' of the rationale for each set of experiments &. The experiments were lo'ical Discussion 1. The students explained clearly the si'nificance of the results obtained and@or 'ave reasons for failures

#. The students compared and contrasted their results to the appropriate literature &. The students were able to su''est further avenues for exploration "esearc& Project "e#ort The format and style of your !esearch Pro"ect !eport for &B06 should be exactly as used in the British :ournal of Pharmacolo'y. Aarks for your !esearch Pro"ect !eport will be awarded accordin' to the followin' table. Please make sure you understand it before you be'in writin'. .heck your final document to ensure that you have not missed any important points. 5n !esearch Papers references to textbooks are not normally considered sufficient1 hence the mention of citations to the primary literature /ie ori'inal research articles0. Title .oncise1 informative1 'rammatical 1 .orrect style 1 Abstract )ummari8es what was done and what conclusions can be drawn # -e! .or$s 6p to seven keywords suitable for literature search purposes 1 .lear B concise1 all statements are relevant & Intro$uction Provides appropriate back'round to the work bein' undertaken & ;efines the -uestions bein' asked # ;escribes experimental methods in sufficient detail to allow repeat $ Met&o$s ;escribes all analytical and statistical methods appropriately $ Properly labelled sample tracin's as appropriate # Properly labelled fi'ures as appropriate # "esults .lear and informative tables as appropriate # )ufficient linkin' text # .lear and concise1 all statements relevant & !esults interpreted appropriately $ Discussion !esults compared and contrasted with the existin' literature $ ,ppropriate analysis of the reliability of the data obtained & vidence of thou'htfulness $ Ackno/le$(ement )uitable acknowled'ements made 1 ,ll non+ori'inal material backed up by references # .itations in text in correct format # "eferences .itations to primary literature when appropriate # !eference list complete1 uses correct format # Presentation Ceat1 no corrections1 spellin' or 'rammatical errors $ TOTAL 0