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Code No: RR322305

Set No. 1

III B.Tech II Semester Supplementary Examinations, Aug/Sep 2006 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13] 2. Dene immunoglobulin and explain about its structure and function. [3+8+5]

3. (a) Describe in brief about the Human MHC class I genes and explain about their functions. [4+4] (b) Describe in brief about Human MHC class II genes and explain about their role. [4+4] 4. Discuss about various types of cell mediator defence mechanism. 5. Dene hybridoma and explain monoclonal antibody production? [16] [3+13]

6. Dene anity and determine antibody anity by equilibrium dialysis method? [2+14] 7. Give an account on the mediators of type I hypersensitivity? [16]

8. Describe dierent types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

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Code No: RR322305

Set No. 2

III B.Tech II Semester Supplementary Examinations, Aug/Sep 2006 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. Explain any two (a) adjuvants. (b) complement. (c) MHC. (d) T cells. 2. Dene immunoglobulin and explain about its structure and function. 3. What are monoclonal antibodies and explain its importance? [3+8+5] [12+4] [8+8]

4. What is meant by cell mediated immunity and explain about the dierent components involved in it. [8+8] 5. Dene cellular immunity and explain the process involved in identication of cell types of immune system? [4+12] 6. Explain ow Cytometry and discuss its role in antigen - antibody interactions? [4+12] 7. Describe the various types of type III hypersensitivity? 8. Explain the signicance of MHCs in graft rejection? [16] [16]

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Code No: RR322305

Set No. 3

III B.Tech II Semester Supplementary Examinations, Aug/Sep 2006 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What is meant by immunity and explain about the various components involved in the immune system. [4+12] 2. Give an account on basic structure of B cells and explain their activation process. [5+11] 3. What is meant by Idiotypic antibodies and explain their role. [11+5]

4. What is meant by phagocytosis and what is its role in the cell mediated immunity. [8+8] 5. Dene hybridoma and explain monoclonal antibody production? 6. Explain the role of cytokines in signal transduction? 7. The DNA vaccines are proved to be highly benecial. Justify? [3+13] [16] [16]

8. Describe dierent types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

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Code No: RR322305

Set No. 4

III B.Tech II Semester Supplementary Examinations, Aug/Sep 2006 IMMUNOLOGY (Bio-Technology) Time: 3 hours Max Marks: 80 Answer any FIVE Questions All Questions carry equal marks 1. What are the various cells involved in the immune response and explain about their role in immune response. [3+13] 2. Explain the process involved in the activation of B cells. 3. What are monoclonal antibodies and explain its importance? 4. Explain various types of cells involved in the cell mediated immunity. 5. Explain the process of formation and selection of hybrid cells? 6. Explain the role of cytokines in signal transduction? 7. Give an account on the signicance of vaccination in Immunology? [16] [12+4] [16] [10+6] [16] [16]

8. Describe dierent types of systemic autoimmune diseases and explain in detail about anyone of them? [4+12]

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