Multidisciplinary Endocrine Oncology Clinic

Hillsboro Endocrine Clinic has been providing individualized and outstanding care for adult
patients with diabetes, thyroid and other endocrine disorders in Washington County and
beyond for over eight years. Our goal is to help patients feel better and to incorporate
treatment plans into each patients busy life, work, and lifestyle.

Fulvestrant 500 mg was also compared with anastrozole 1 mg/day in the metastatic setting in
the phase II FIRST trial ( n = 205). TTP was significantly prolonged with fulvestrant 500 mg
(hazard ratio = 0.626; P = 0.0496) 40 . Adverse events were comparable between treatment
arms. Data from the FIRST study showed that the significant difference in TTP had persisted
with longer follow-up (23.4 months with fulvestrant versus 13.1 months with anastrozole;
hazard ratio = 0.66; P = 0.01) 41 . Some disorders like low thyroid hormone production or
hypothyroidism deals only with an endocrine organ and an endocrinologist alone may detect,
diagnose and manage such patients.

In many cases, the exact cause of a particular endocrine disorder is not known. Often,
hormones interact with each other, so symptoms of a particular endocrine disorder may be
nonspecific. It is important to seek medical evaluation if you believe you may have an
endocrine disorder, as direct assessment of hormone levels may help find and fix the
underlying cause of hormone imbalance. What are the risk factors for endocrine disorders?
Our study results suggest an at most modest concordance between adherence measures
tested in a sample of breast cancer patients receiving endocrine treatment. Given
correlations of 0.2-0.4, the comparability of results using these study methods is rather
limited.

Dr. Alexander Shifrin, an Endocrine Surgeon from Jersey Shore University Medical Center,
presented a poster entitled Use of molecular markers on FNA biopsies of thyroid nodules, as
recommended by recent ATA guidelines, modifies surgical treatment of thyroid nodules and
thyroid cancer. The poster describes the results of his recent independent evaluation of the
miR Inform Thyroid Panel and its impact on improving the surgical management and
treatment of patients with suspicious or positive thyroid FNA cytology. Predefined adverse
events at the updated analysis of the ATAC trial for which there were significant differences
between anastrozole and tamoxifen at the first analysis

This diagnosis is stressful, and this is difficult to discuss for many people. However, it is
important to have open and honest conversations with your doctor and health care team to
express your feelings, preferences, and concerns. The health care team is there to help, and
many team members have special skills, experience, and knowledge to support patients and
their families. Making sure a person is physically comfortable and free from pain is extremely
important. For germ cell tumors, current efforts are focused on reducing the amount of
chemotherapy while maintaining the excellent cure rates. Because these tumors are so rare,
clinical trials are done in national, multi-institutional collaborations.

Although difficult for parents, it is important not to assign a sex to an affected newborn until
after proper diagnosis is agreed upon by the parents and team of doctors. We think this
because it is more difficult for families to reassign a baby's sex than to postpone an initial
assignment until after a diagnosis is agreed upon. Endocrinologists treat patients who are
overweight or obese, sometimes because of metabolic and hormonal problems. When
someone is obese they have too much body fat. Thyroid, adrenal, ovarian, and pituitary
disorders can cause obesity. Endocrinologists also identify factors linked with obesity, such
as insulin resistance and genetic problems.

On one hand, they can increase a patient's risk for heart attack, stroke, uterine cancer and
blood clots in veins of the legs. When they first take the drug, some women also experience
what are known as flares. The flares may involve an increase in pain and in the size of
tumors located near the skin's surface, but these effects usually pass endocrino Barcelona in
a few weeks, and the worst symptoms can often be controlled with other medications. Dr.
Harrell and Dr. Golding personally perform diagnostic high-resolution ultrasound imaging and
thyroid, parathyroid and neck lymph node biopsies in highly sophisticated ultrasound suites.
They have each performed thousands of these diagnostic procedures.

Previously, scientists and doctors believed that the bone was only a target for hormones
made elsewhere in the body, but recent studies have shown that proteins produced by
skeletal cells can affect the pancreatic secretion of insulin, elevating bone to the status of an
endocrine organ. Bone cells in the skeleton help regulate phosphate homeostasis, and
proteins produced by skeletal cells can affect the pancreatic secretion of insulin, explains Dr.
Rosen, Director of Clinical and Translational Research, Maine Medical Center. Bones are
actually secreting hormones that can influence many other tissues.