• Introduction
• Important aspects in design and
operation of the extraction processes.
• Selectivity and Distribution coefficient
• Extraction techniques
• Extraction apparatus and equipment
Definition
S
Extract
S+B
A+B
A + eB
Raffinate
Extraction
Partition between two phases
Liquid/solid,
gas/liquid,
liquid/liquid
• Mixture dissolved in
solvent 1 & placed in
separatory funnel
• Immiscible solvent 2
added, stoppered &
agitated
• Mixture components
distribute according to
solubility
• Bottom layer drained
through stopcock to
separate phases
Microscale Extraction
• Mixture dissolved in
solvent 1 in a
centrifuge tube
• Immiscible solvent 2
added & agitated
• Bottom layer
removed with
Pasteur pipet &
transferred to clean
tube
The following need to be carefully evaluated
when optimizing the design and operation of
the extraction processes.
•Solvent selection
•Operating Conditions (pH,T,P & residence time)
•Mode of Operation
•Extractor Type
•Design Criteria
Selection of solvent influenced by
• -its physico-chemical properties (allowing an easy
recovery of the solute or of the solvent),
• -a negligible solubility of the solvent in the diluent
(post-extraction processes have to be as cheap as
possible),
• -physical characteristics offering acceptable
dispersion and separation times of the post-contact
phases (viscosity, interfacial tension, density
difference compared to the feed),
• -favorable properties (Mass transfer kinetics –
equilibrium after contact less than a few minutes - ;
Economy – cheap and available solvent - ; Safety of
use – low toxicity, low flammability, low volatility,
low corrosion in comparison with usual
construction materials -),
But particularly a property called selectivity
Selectivity can be defined as the ability of the solvent to pick up the
desired component in the feed as compared to other components. The
desired properties of solvents are a high distribution coefficient, good
selectivity towards solute and little or no miscibility with feed
solution. Also, the solvent should be easily recoverable for recycle.
The higher the m, the higher β and thus the more selective the solvent.
Single Counter-
stage current
with reflux
Cross- Counter-
current current
1. http://iweb.tntech.edu/chem311dc/
LabPDF/Extraction.pdf
2. Paul Ashall 2007. Liquid-liquid extraction
principle
3. Nadine LE BOLAY, Gilbert CASAMATTA.
Liquid extraction