requires higher pressure as compared to a previously ventilated lung
The APGAR score in one minute determines the need for resuscitation Sign 0 Points 1 Point 2 Points Appearance Blue all over Pink torso, blue extremities Pink torso & extremities Pulse Absent <100 bpm >100 bpm Grimace No response to stimuli Limited cry Vigorous cry Activity Flaccid Limited movement Actively moving Respiratory Effort Absent Hypoventilation, irregular Strong loud cry
1 minute APGAR score 0-4 Severe depression, requiring immediate resuscitation 5-7 Some nervous system depression 8-10 normal
CARDIOPULMONARY ADAPTATION
INTRAUTERINE: The newborn breathes by utilizing placental oxygen. AFTE R DELIVERY: The newborns first challenge is to breathe independently.
At birth, the baby's lungs are filled with amniotic fluid and are not inflated. As the newborn is expelled from the birth canal, its central nervous system reacts to the sudden change in temperature and environment. This triggers it to take the first breath, within about 10 seconds after delivery. With the first breaths, there is a fall in pulmonary vascular resistance, and an increase in the surface area available for gas exchange. Over the next 30 seconds the pulmonary blood flow increases and is oxygenated as it flows through the alveoli of the lungs.
PRENATAL OR PERINATAL RISK FACTORS FOR NEONATAL ASPHYXIA
Antepartum Reasons to Suspect a Depressed or Aphyxiated Newborn Intrapartum Reasons to Suspect a Depressed or Asphyxiated Newborn Maternal age <16 or >35 yrs Abnormal fetal heart rate - fetal bradycardia - non-reassuring fetal heart rate patterns Maternal diabetes Meconium stained fluid Maternal hypertension Polyhydramnios Pregnancy-induced hypertension Abnormal presentation Chronic maternal illness Premature labor Maternal hemorrhage Prolonged labor (>24 hrs) Maternal infection Prolonged 2 nd stage (>2 hrs) Premature rupture of membranes Cord prolapsed Maternal drug therapy Use of general anesthesia Maternal drug dependence Emergency caesarean section Polyhydramnios / oligohydramnios Forceps or vacuum-assisted delivery Anemia / isoimmunisation Breech / other abnormal presentation Previous Rh sensitization Foul smelling amniotic fluid Post-term gestation Chorioamnionitis Multiple gestation Abruption placentae Size-dates discrepancy Placenta previa Previous stillbirth Prolonged rupture of membranes (>18 hrs before delivery) Fetal malformation Uterine tetany Diminished fetal activity No prenatal care
EFFECTIVE RESUSCITATION Prevents morbidity and mortality associated with hypoxic-ischemic encephalopathy and hypoxic complication especially affecting the brain, heart and kidneys. Brain hypoxia for 3-4 mins can lead to irreversible brain damage
MAIN GOAL OF RESUSCITATION: To establish an adequate spontaneous respiration and cardiac output at the soonest possible time.
INFANT WHO REQUIRES IMMEDIATE RESUSCITATION ( without bothering to do the APGAR scoring ) born limp cyanotic apneic pulseless
ABCs OF RESUSCITATION guiding rule in resuscitating a depressed newborn
AIRWAY must be immediately cleared of any matter such as fluid and blood meconium-stained amniotic fluid must be completely suctioned before positive breathing can be applied or before positive breathing can be applied or before the infant makes a gasping attempt RECOMMENDED: the OB should suction the oropharynx as soon as the babys head is delivered and before the shoulders are delivered IN CASE THE INFANT IS MAKING SOME RESPIRATORY EFFORT NOTE FOR: Stridor and suprasternal retractions R/O choanal atresia BREATHING initiated either with bag and mask or with direct endotracheal intubation ambubag for 60-80/minute when there is poor response to ventilation endotracheal intubation: performed in infants who do not respond to initial bag and mask ventilation
CIRCULATION may require cardiac massage
DRUGS Naloxone: if the mother received narcotics 0.1 mg/kg IV or intratracheally
ENVIRONMENT: thermal environment Infant should be placed under a radiant heater or any heat source Should be immediately dried Head positioned downwards and slightly extended
CHEST COMPRESSION HR: below 80 bpm after manually ventilating the infant CURRENT RECOMMENDATION: place the two thumbs on the middle of the sternum below an imaginary line between the nipples the rest of the fingers encircling the chest depth: 1/2 - 2/3 inch rate: 120/min compression/ventilation ratio: 3:1 most effective treatment for hypoxia: ventilation with 100% oxygen Epinephrine Asystole 0.1-0.3 ml/ kg IV or intratrachel May be repeated every 5 minutes If unresponsive: use 5-10x the standard dose of epinephrine
Sodium bicarbonate 1-2 mEq/kg 0.5 mEq/ml of a 4.2% solution Given slowly If the resuscitation is prolonged and there is persistent metabolic acidosis Should always be diluted with equal amounts of IV fluid
DOPAMINE or DOBUTAMINE Cardiogenic shock secondary to severe asphyxia Continuous infusion 5-20 ug/kg/min
AFTER SUCCESSSFUL RESUSCITATION In the NICU: Infants multiple organ functions must be monitored closely regardless of the severity of asphyxia or response to resuscitation