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PATHOPHYSILOGY of APPENDICITIS

Predisposing factors Precipitating factors:


- Age: 18 years old - Unhygienic practices
- Diet
LEGEND:

- signs/symptoms
Fecal obstruction, swelled lymph nodes, bacteria
simultaneously released
!iruses, proto"oa etc#
- $tiology

nursing diagnosis
%cclusion o& Appendi' by Fecalith
(is) Factors
Decreased *ow/drainage o& mucosal secetions
+ncreased +,- in the appendi'
.asocongestion /0$,,+12
and -A+1
Decreased per&usion in the appendi'

3ypo'ia in the appendi'
-yrogens

Appendi' starts to be necrotic4 5acteria in!ade the appendi'
3ypothalamus
Disruption o& 6ell 7embrane o& Appendi' Fe!er
/tart o& +n*ammatory -rocess

(elease o& 6hemical 7ediators Acti!ation o& the .omiting +n*ammation
o& Appendi' 8Appendicitis9
6enter in the 7edulla

Appendectomy +mpaired tissue

integrity
/uppression o&
:issue trauma
6hemical mediators sympathetic 2+ Function

(is) &or
in&ection
7ast cells Anore'ia
5rady)inin -rostaglandins 3istamine ,eu)otrienes disruption o& 6ell
membrane 1ociceptors on the

Dermis
-A+1 !asoconstriction (is) &or De;cient (is) &or +mbalanced start o&
in*ammatory /end impulses to 61/
Fluid !olume nutrition less than
process
.asodilation body re<uirements
+nterleu)in-1 release o&
-rostaglandin,
+ncrease permeability 5rady)inin,
3istamine, ,eu)otrienes
+ncreased 056 and other
chemical mediators

Accumulation o& 056 to the
+nterstitial *uid or compartment
-ain

-hagocytosis

/0$,,+12 $'udates
(is) &or +n&ection
8+& appendi' ruptured9