IUPAC

5-Hydroxytryptamine or
3-(2-aminoethyl)-1H-indol-5-ol

5-Hydroxytryptamine, 5-HT,
Enteramine; Thrombocytin, 3-(Aminoethyl)-5-hydroxyindole,
Thrombotonin

CAS

50-67-9

PubChem

5202

ChemSpider 5013

SMILES

InChI

InChIKey

QZAYGJVTTNCVMB-UHFFFAOYAX

ChEBI

28790

KEGG

C00780

MeSH

Serotonin

IUPHAR
5

C10H12N2O

176.215 g/mol gmol

White powder

121122C(ligroin)[1]

416 30.0C(at 760 Torr)[2]

slightly soluble

2.98 D

MSDS

External MSDS

LD50

750 mg/kg(subcutaneous, rat),[3]

4500 mg/kg(intraperitoneal, rat),[4]
60 mg/kgoral, rat

25
100 kPa

Serotonin 5- 5-HT
5- 5-

2%
[5][6] 5-HT
8%-9%
5-HT 5-HT 5-HT
5-HT
[7]
5-HT -

5-HT

5-HT

5-HT 5-HT
5-HT
5-HT 7 5-HT
5-HT3 6 G
7 3 3 5-H
5-HT 1.
5-HT 5-HT 5-HT3

 5-HT 5HT2
5-HT 5-HT2
2. 5-HT 5-HT2
5-HT4
5-HT
3. 5-HT
5HT 5-HT
5-SSRIs
MAOIs 5-HT

MAO 5- 5-
5-HT
MAO

5 5-5HILL5-

B6

50 B6 100
B6
50mg-2000mg B6

Serotonin is a neurotransmitter, a naturally occurring chemical that can influence mood and appetite. B
complex vitamins, such as thiamine and folic acid, also affect serotonin. Doctors prescribe
antidepressants to help raise the brain's serotonin levels in people suffering from depression. The brain
uses the amino acid tryptophan to produce serotonin, as long as the process is not blocked by conflicting
amino acids. Serotonin is also found in the digestive system, and certain foods may raise or lower
serotonin levels. Diets lacking in tryptophan may cause people to have low serotonin levels and to
experience depression, headaches and sleep disorders.

Grains
Foods rich in vitamin B such as brown rice, wheat germ, wholegrain cereals, yeast extracts and brewers'
yeast, help with serotonin production, according to Scottish general practitioner and author, Dr. Dan
Rutherford of NetDoctor. Eating granola, oatmeal, whole grain cereal or a whole grain muffin for breakfast
will start your day with nutrients that help boost serotonin.

Fish, Poultry and Meat

Salmon, fresh tuna, snapper, sardines, herring, mackerel and halibut are high in tryptophan and excellent
sources of serotonin, according to the World's Healthiest Foods nonprofit website. Poultry, such as
chicken and turkey are excellent sources of the tryptophan necessary for serotonin to stay at an optimal

level in the body and brain. Meat, including beef, lamb and liver can provide amino acids and other
nutrients that facilitate the creation of serotonin.

Nuts and Seeds

Walnuts are especially beneficial for serotonin production. Flaxseeds, sunflower seeds, pumpkin seeds,
sesame seeds, peanuts, almonds and cashews can increase serotonin in the body.

Oils
Essential fatty acids increase serotonin production. These nutrients include the omega-3 fatty acids found
in fish, walnut and flax oil. Omega-6 fatty acids are found in canola, grapeseed, safflower, sunflower and
wheat germ oils. Gamma-linoleic acid is found in spirulina or blue-green algae and black currant, evening
primrose and borage oils.

Dairy
Eggs are protein rich and contain amino acids and essential fatty acids necessary to produce serotonin.
Egg whites are ranked very high on the serotonin food list. Lower levels of tryptophan are found in milk
and a variety of cheeses, according to Outofstress.com. Cottage cheese and yogurt are also good foods
to eat to increase and maintain your serotonin levels.
(reference 3)

Fruits
Bananas, kiwi, pineapple, plantains, plums, grapefruit, mango, honeydew and cantaloupe have a high
serum concentration, which makes them very useful in serotonin production. Tomatoes and avocado are
also rich in nutrients necessary for serotonin to develop and reach optimal levels in the brain.

Vegetables
Corn, broccoli, cauliflower and green leafy vegetables such as spinach are serotonin-rich, as are baked
potatoes with skin, mustard greens and mushrooms. Soy products, including soy milk, tofu and soybeans
provide nutrients that help serotonin levels stay stable.

Sea Vegetables
Sea vegetables include kelp, seaweed and spirulina -- a blue-green algae -- contain tryptophan, an
essential amino acid that is necessary for creating serotonin in the brain.

Legumes and Beans

Lentils, mung beans, chickpeas, peas, cooked beans -- kidney, black, lima, navy and pinto -- are good
sources of serotonin, as are foods such as hummus and lentil soup, which are made with these products.

Read more: http://www.livestrong.com/article/288554-list-of-foods-with-serotonin/#ixzz2nQY71erO