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1. BRIEF PROFILE



Name : Rupinder Tewari
Address: Professor and Coordinator,
Centre for Microbial Biotechnology,
Panjab University,
Chandigarh 160014
Email: rupinder@pu.ac.in

Ph. No.+91-9872216184

D.O.B/sex: Sept. 27, 1956; male



Fields of specialization: Microbiology and Microbial Biotechnology
B.Sc (Hons. School), M.Sc (Hons. School), Deptt. of Microbiology, Panjab University,
Chandigarh.
Ph.D (Microbiology), Panjab University, Chandigarh.
Ph.D. (Microbiology), University of London, London, U.K.
Post Doctorate Fellow ,Washington University, St. Louis, MO, USA.
Recipient of :
(i) Rockefeller Biotechnology Fellowship awarded by The Rockefeller
Foundation, USA.
(ii) Commonwealth Academic Staff Scholarship awarded by The British Council,
U.K.
Fellow, Panjab University Senate (2008 onwards),
Dean (Faculty of Sciences) (2012 onwards)
Founder, Centre for Microbial Biotechnology, PU, Chd. (2008)
Chief-Mentor, Centre for Innovation Cluster in Biotechnology (CIC-B) (2014
onwards) Funded by BIRAC-NInC (GOI, New Delhi)
Coordinator, DST-Policy Research Centre on Promotion of Industry-Academia
interactions. (2013 onwards)
Coordinator, Chandigarh Innovation & Knowledge Cluster (CRIKC) (2013 onwards)
Formerly Director (Hony.), Centre for Industry-Institute Partnership programme
(CIIPP) of PU, Chd. (2012-13).
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Formerly, Chairman, Deptt. of Biotechnology, Panjab University, Chandigarh.
(2004-05)
Formerly, Coordinator, UGC-SAP, Dept. of Biotechnology, PU, Chd.(2005-09)
Formerly, Coordinator, UGC-NET exams held in Dec.2008 and June, 2009.
Formerly, Coordinator, PU Ph.D Entrance exam held in 2009 & 2010
Formerly, Chairperson, UG-CET Admissions of PU in 2010 & 2013.
Granted research projects by agencies like DBT, DST, CSIR, ICMR and UGC.
Research publications in high impact journals (Acta Crystt., JBC, Infect. Immun.,
Appl. Environ. Microbiol., BioResource etc.).
Submitted many gene sequences in GenBank
Submitted many protein structures in Protein Data Bank (PDB).
Submitted many microbial cultures in MTCC, IMTECH (CSIR branch), Chandigarh
Published three books in the areas of Microbiology/Biotechnology. Fourth will be out
soon.
Written two e-chapters on Industrial Microbiology (80 pages) and DNA Replication
(60 pages) for NISCAIR (CSIR, New Delhi)
Guided 24 Ph.Ds. students and more than 40 M.Sc students for their theses /
dissertations.10 research scholars pursuing Ph.D.
Organized various National/ International Conferences/Seminars/Workshops.
Chaired sessions in National / International conferences
Delivered more than 50 invited lectures at various places including JNU (New
Delhi); IISc (Bangalore); BHU (Banares); Indian Science Congress (2014); CSIR
Regional Research Laboratory (Jammu); JALMA (Agra); Univ. of Pune, Pune; Anna
University, Chennai etc.
Member, Board of Editors of Indian Jr. of Microbiology (2009-11)
Reviewer, many journals (national and internationals)
Designed Biotechnology Policy-2004 for U.T. (Chandigarh).
Founder, Chandigarh chapter, Association of Microbiologists of India (AMI)




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2. TEACHING & RESEARCH EXPERIENCE

-- 35 years. (UG, PG and PhD course work)

Introductory Microbiology
Industrial Microbiology
Environment Microbiology
Recombinant DNA Technology
Microbial Biotechnology
Bio-safety Guidelines, GLP, GMP





3. RESEARCH PROJECTS (Funded)

(i) Cloning of Penicillin G Acylase (pga) gene in 100% stable asd
+
vector and
its expression in asd
-
E.coli . (1996-99). Funding agency: CSIR, New Delhi.

(ii) Biodegradation of Nitro-aromatic compounds by microbes. (2002-05).
Funding Agency: DRDO, New Delhi.

(iii) Microbial consortium of Phosphate solubilizers and their genotyping.
(2003-06). Funding agency: UGC, New Delhi.

(iv) Production and purification of pectinase from a Bacillus sp.
Funding Agency: UGC, New Delhi (1997-2000).

(v) Construction of illuminating bacteria for the detection of toxic compounds
present in the water samples. (2003-05) Funding agency: DST, New Delhi.

(vi) Cloning, expression and purification of aspartate semialdehyde
dehydrogenase of Mycobacterium tuberculosis. Funding Agency: DBT,
New Delhi (2003-06)

(vii) Cloning of chitinase gene of Enterobacter sp. NRG4 and
characterization and applications of recombinant chitinase. (2006-09).
Funding agency: DBT, New Delhi.

(viii) Characterization of antimicrobial compounds of Burkholderia gladioli.
(2007-08) Funding agency: DBT, New Delhi.

(ix) Structure determination of aspartate semialdehyde dehydrogenase of
Mycobacterium tuberculosis. (2008-10) Funding agency: DBT, New Delhi.
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(x) Biotechnological route for the production of N-acetyl-D-glucosamine: a
pain killer. (2011-14). Funding agency: UGC, New Delhi

(xi) Cloning, expression, purification and structure determination of MurA of
Mycobcaterium tuberculosis (2011-14). Funding agency: DST, New Delhi



4. M.Sc. / Ph.D SUPERVISOR

(i) Guided over 40 M.Sc students for their dissertations
(ii) Guided 24 Ph.D students ; Guiding 10 Ph.D students


5. RESEARCH PUBLICATIONS (Impact factor > 3.0)
(Total research publications 78)

1. S. Walia, T. Madhavan, R. Tewari (1986). Protein patterns, serotyping & plasmid
profiles in the epidemiological finger printing of Ps. aeruginosa. Eur. J. Clin.
Microbiol. & Infec. Dis. 7(2): 279-285. (IF: 3.024)
2. S. Walia, T. Madhavan, R. Tewari (1986). Plasmid profiles and klebocin types in
epidemiological studies of infections by Klebsiella pneumoniae. Eur. J.Clin.
Microbiol. & Infec. Dis. 7(2): 279-285. (IF: 3.024)
3. A. Khan, R. Tewari, S. Walia (1988). Molecular cloning of 3-phenylcatechol
dioxygenase involved in catabolic pathway of biphenyl from Pseudomonas putida
and its expression in E.coli. Appl. Environ. Microbiol. 54: 2664-71. (IF: 3.678)
4. R. Tewari, S. Hultgren, S. Abraham (1993). Neutrophil activation by nascent
FimH subunits o Rf Type 1 fimbriae purified from the periplasm of Escherichia
coli. J.Biol. Chem. 268(4): 3009-15. (IF: 4.651)
5. R. Tewari, T. Ikada, S. Abraham (1995). The PapG tip adhesin of P fimbriae
protects E.coli from neutrophil bactericidal activity. Infect. Immun. 62(12): 5296-
5304. (IF: 4.074)
6. D.R. Kashyap, P.K. Vohra, R. Tewari (2000). Applications of Pectinases: A
Review. Biores. Technol. 77(3): 215-227. (IF: 4.750)
7. G. Chaturvedi, R. Tewari, N. Mrigank, N.K. Ganguly (2001). Inhibition of
Helicobacter pylori adherence by a peptide derived from neuraminyl lactose
binding adhesin. Molec. Cell. Biochem. 228: 83-89. (IF: 5.372)
8. G. Hoondal, R.P. Tiwari, R. Tewari, N. Dahiya (2002). Microbial alkaline
pectinases and their industrial applications: a review. Appl. Microbiol.
Biotechnol. 59: 409-418. (IF: 3.689)
9. D.R. Kashyap, S.K. Soni, R. Tewari (2003). Enhanced production of pectinase
by Bacillus sp. DT7using solid-state fermentation. Biores. Technol. 88: 251-54.
(IF: 4.750)
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10. N. Dahiya, R. Tewari, G.S. Hoondal (2006). Biotechnological aspects of
chitinolytic enzymes: a review. Appl. Microbiol. Biotechnol.. 71(6): 773-82. (IF:
3.689)
11. V. Mittal, O. Singh, H. Nayyar, J. Kaur, R Tewari (2008). Stimulatory effect of P-
solubilizing fungal strains (Aspergillus awarmori and Penicillium citrinum) on the
yield of chickpea (Cicer arietinum L. cv. GPF2). Soil Biol. Biochem. 40: 718-727
(IF: 3.654)
12. P. Rishi, S. Mavi, S. Bharhan, G. Shukla, R. Tewari (2009). Protective efficacy of
probiotic alone or in conjugation with a prebiotic in Salmonella induced liver
damage. FEMS Microbiol. Ecol. 69(2): 222-30. (IF: 3.563)
13. A. Garg, R. Tewari, G.P.S. Raghav (2010). KiDoQ: using docking based energy
scores to develop ligand-based model for predicting antibacterials. BMC
Bioinformatics 11:125 doi:10. 1186/1471-2105-11-125. (IF: 3.02)
14. A. Garg, R. Tewari, G.P.S. Raghav (2010). Virtual Screening of Potential Drug
like inhibitors of Mycobacterium tuberculosis. BMC Bioinformatics.11 (suppl.):
S53. (IF: 3.02)
15. A. Gautam, R. Vyas, R. Tewari (2010). Peptidoglycan Biosynthesis Machinery:
A rich source of drug targets. Crit. Rev. Biotechnol. 31 (4): 295-336. (IF: 5.095)
16. S. Khan, V. Bhakuni, V. Praveen, R. Tewari, C.K.M. Tripathi, V.D. Gupta (2010).
Maximizing the native concentration and shelf life of protein: a multiobjective
optimization to reduce aggregation. Appl. Microbiol. Biotechnol. 89(1): 99-108.
(IF: 3.689)
17. R. Vyas, R. Tewari, M, Weiss, S.Karthikeyan (2012). Crystal structures of ternary
complexes of aspartate semialdehyde dehydrogenase (Rv3708c) from
Mycobacterium tuberculosis H37Rv. Acta Crystallogr. D68, 671-679 (IF 11.2)

6. Books

R. Tewari, K.G. Mukerji, J.K. Gupta and L.K. Gupta (2001) Role of Microbes in
the Management of Environmental Pollution. A.P.H. Publishing Corporation,
New Delhi. ISBN : 81-7648-223-4
Tiwari, R. P., Hoondal, G. S. and Tewari, R. (2004). Laboratory Techniques in
Microbiology and Biotechnology. Abhishek Publishers, Chandigarh . ISBN:
8182470773
Tewari R (2007) Invitation to Biotechnology. Viva Publishers, New Delhi.
ISBN: 81-309-0599-X
Guest Editor of a book, Microbial Biotechnology, a multi volume set on Recent
Developments in Biotechnology. Publisher: Studium Press LLC, Houston, USA.
Will be in market by end of 2014.

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7. e-Chapters for NISCAIR (CSIR, GoI)
Tewari, Rupinder (2008) Industrial Microbiology.
http://hdl.handle.net/123456789/684
Tewari, Rupinder (2008) DNA Replication. http://hdl.handle.net/123456789/685

8. Gene sequences submitted to GenBank
S. No. Accession no. Organism Gene
1. GQ906590 Escherichia coli Chitobiase (chb)
2.
AY754011

Enterococcus
faecium
Vancomycin resistance protein A (vanA)
3. AY751080
Enterococcus
casseliflavus
Vancomycin resistance protein C2
(vanC2)
4. AY372113
Mycobacterium
tuberculosis H37Rv
Aspartate semialdehyde dehydrogenase
(asd)
5. GU166748
Pseudomonas
aeruginosa strain
PAO1
Dihydrodipicolinate synthase (dapA)

6. EU840989
Mycobacterium
tuberculosis H37Rv
UDP-N-acetylenolpyruvylglucosamine
reductase (murB)
7. DQ013365
Enterobacter sp.
NRG-4
Chitinase (chiA) gene
8. AY786180
Enterococcus
gallinarum
Vancomycin resistance protein C1
(vanC1)
9. AY786179
Enterococcus
gallinarum
Vancomycin resistance protein B (vanB)


9. Proteins Structures submitted to Protein Data Bank (PDB)

S. No. PDB-ID Organism Enzyme
Resolution
()
1. 3LLG
Mycobacterium
tuberculosis H37Rv
Aspartate semi-aldehyde dehydrogenase 2.18
2. 3PUL
Acinetobacter
baumannii
Dhydrodipicolinate synthase 2.30
3. 3PUO
Pseudomonas
aeruginosa
Dihydrodipicolinate synthase 2.65
4. 3PUD
Acinetobacter
baumannii
Dhydrodipicolinate synthase 2.80
5. 3PUE
Acinetobacter
baumannii
Dhydrodipicolinate synthase 2.60
6. 3PS7
Pseudomonas
aeruginosa
Dihydrodipicolinate synthase 2.85
7. 3KUB
Mycobacterium
tuberculosis H37Rv
Aspartate semi-aldehyde dehydrogenase 2.43
8. 3NOE
Pseudomonas
aeruginosa
Dihydrodipicolinate synthase 2.95
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10. Bacterial strains submitted to Microbial Type Culture Collection Centre
(MTCC) , IMTECH (CSIR Branch) Chandigarh




11. WORKSHOPS / CONFERENCES ATTENDED

More than 40 papers presented in National and International conferences (USA,
UK, Canada)
Organized various conferences/Workshops/Seminars/Special Lectures by
National and International scientists
Chaired sessions in various conferences (national & international)







S. No. Organism MTCC Accession #
1. Aspergillus awamori VQ2 8002
2. Aspergillus awamori VH1 8003
3. Penicillium citrinum VPT 8004
4. Penicillium citrinum VU1 8005
5. Penicillium citrinum VR250 8006
6. Penicillium citrinum VPC 8007
7. Burkholderia gladioli 10216
8. Burkholderia gladioli 10217
9. Serratia marcescens 10238
10. Enterobacter aerogenes 10208
11.
Pseudomonas synxantha 10223
12. Burkholderia gladioli 10242
13. Enterobacter hormaechei 10240
14. Serratia marcescens 10241
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12. INVITED LECTURES

Delivered more than 40 invited lectures at various institutes including JNU (New Delhi),
IISc (Bangalore), Pune University (Pune), Anna University (Chennai), RRL (Jammu),
HPU (Shimla), Punjabi University (Patiala), HAU (Hissar).



13. MEMBERSHIP of SOCIETIES

1. Association of Microbiologists of India.( AMI).-- Life Member
2. All India Biotech Association (AIBA)---- Life Member
3. Electron Microscope Society of India. (EMSI)---- Life Member
4. Biosensor Society of India --- Life member
5. Society for Promotion of Science & Technology in India --- Life Member
6. Environmental Society of India.
7. American Society of Microbiology (1990-97)
8. Canadian Society of Microbiology (2000-02)
9. Society for Promotion of Science & Technology in India