A Case Study about Adult Conjunctivitis In Partial Fulfillment of the Requirements in MICROBIOLOGY AND PARASITOLOGY
by
Bugarin. Mark Ernest P. Caballero, Kayla Marie Carmelo, Maricris R. Castro, Ma. Luisa Cercado, Jeniffer M. De Jesus, Gabriel M. Del Rosario, Klarisse Jane R. Delos Reyes, Ivy Katrina P.
Submitted to: Ms. Serrana
October 20, 2010
1. Etiologic agent The etiologic agent of Adult Conjunctivitis is Chlamydia trachomatis.
2. Signs and symptoms Redness and tearing Itching Swollen eyelid Discharge (watery or thick) Crust that forms overnight Sensitivity to light Gritty feeling abdominal pain low-grade fever
3. Laboratory Diagnostic Procedure The Laboratory Diagnostic procedure includes the cell culture, direct fluorescent monoclonal antibody staining of smears, enzyme immunoassays for Chlamydia organisms, DNA hybridization assays and a polymerase chain reaction test to identify chlamydial antigens. Many ophthalmologists obtain conjunctival cytology scrapings for Gram's staining and/or Giemsa staining to help characterize the conjunctival inflammatory response. The findings can be helpful, particularly for diagnosing allergic, chlamydial and certain atypical forms of conjunctivitis in which the clinical diagnosis is not immediately apparent. 4. Mode of Transmission The mode of transmission is mainly through vaginal and anal sex; although it is much less common, it can also be passed on via oral sex, hand to eye contact and indirect contact. 5. Complication The trachoma serovars of C. trachomatis inclusion conjunctivitis secondary to genital tract infection, there is not the same likelihood of re-infection. Furthermore, in developed countries there is a greater likelihood that the infection will be treated promptly. Thus conjunctival scarring is rarely a complication of adult inclusion conjunctivitis, although micro-pannus, and micro ulceration of the cornea following punctate keratitis do, rarely, occur.
6. Treatment The treatment is essential that all patients with chlamydial conjunctivitis and their sexual partners are examined and treated for concomitant chlamydial genital tract infection. Inclusion conjunctivitis generally responds well to the kind of regimens of macrolide or doxycycline used for treating chlamydial genital tract infection. In the case of doxycycline, treatment with a weekly dose of 300 mg for three weeks or a daily dose of 1.5 mg/kg of body weight (100 mg) for one week produced a clinical and microbiological cure in 100% of 93 patients with adult chlamydial conjunctivitis. However, mild to moderate papillary responses persisted in some patients up to six months from completion of their treatment. The best results were obtained with a daily dose of 100 mg for two weeks, which produced rapid clinical and microbiological cure in all patients. The use of azithromycin for the treatment of trachoma suggests that it is likely to be a convenient and effective drug for use in treating adult chlamydial inclusion conjunctivitis.
7. Prevention Personal hygiene is of ultimate importance. This includes washing the body regularly, especially after returning from outdoors. Clothes must be changed after each outing, and everyday a washed pair of clothes must be worn. Be wary of moving around much in crowded public places. Articles such as towels, combs, pillow covers and soaps must not be shared. Also, clothing items must be washed after each u If a person has conjunctivitis, then the following preventions must be undertaken:- Do not rub your eyes. If only one eye is affected, then rubbing will cause the discharge to go into the other eye and that too will get affected. Do not use your hands to wipe the eyes. This can be spread onto others. In order to ease the pain, you can use a cold compress. Do not wear spectacles or contact lenses while affected. Alternatively, you can change your eye wear once treated. Do not use any cosmetics on the eye or the nearby regions. Do not allow your clothes or beddings to mix with those of other people.