CERTIFICACION HACCP

De importancia fundamental para las empresas alimentarias, esta certificacin encuentra su

fundamento en la actuacin de normas comunitarias relativas al control de los puntos crticos.
La norma ha sido confirmada en Italia con el Decr. Leg. 155/97.
Las empresas estn obligadas a garantizar que el tratamiento de los productos alimentarios
proceda de manera higinica.
El responsable de la empresa tiene la obligacin de hacer el autocontrol siguiendo el sistema
HACCP:
1. anlisis de los posibles riesgos para los clientes
2. individuacin de los momentos en que se puedan producir riesgos para los alimentos
3. medidas para tomar respecto a los momentos detectados (osea aquellos momentos de la
produccin en que el producto puede ser afectado por algn factor)
4. individuacin de procediminetos de control de los momentos ms sensibles
5. examen peridico de los riesgos, de los momentos sensibles y de los procedimientos de
vigiliancia.
El desarrollo de un Sistema de Gestin de la Seguridad Alimentaria representa un
acercamiento sistemtico a la prevencin y a la mxima reduccin del riesgo alimentar.

CERTIFICACION ISO 9001

La certificacin ICONTEC ISO 9001, Sistema de Gestin de la Calidad, proporciona una base
slida para un Sistema de Gestin, en cuanto al cumplimiento satisfactorio de los requisitos del
sector y la excelencia en el desempeo, caractersticas compatibles con otros requisitos y
normas como el Sistema de Gestin Ambiental, Seguridad, Salud Ocupacional y Seguridad
Alimentaria, entre otros.
CERTIFICACION BPM


BPM significa Buenas Prcticas de Manufactura en la industria. Sus disposiciones se aplican
a nivel de las instalaciones de la planta de produccin; de los equipos y utensilios utilizados; de
los requisitos higinicos de fabricacin a nivel de personal; de las materias primas e insumos
utilizados; de las operaciones de produccin; del envasado, etiquetado y empaquetado; del
almacenamiento, distribucin, transporte y comercializacin, del aseguramiento y control de
calidad.

HUMANITAS INTERNATIONAL FOUNDATION

Humanitas International Foundation tiene la Misin de disear, desarrollar, promover, y
ejecutar programas de promocin para la salud, dirigidos a la poblacin general y otros
auditorios: programas que sern diseados y preparados para mejorar el conocimiento sobre la
salud, pero principalmente hacerse instrumentos prcticos que ayuden a la humanidad a
alcanzar y mantener la salud y el bienestar general.



EMPRESA PERUANA DEL AO

Organizado por la Asociacin Civil Empresa Peruana del Ao desde hace 17 aos, el Premio
Empresa Peruana del Ao cuenta con el respaldo de prestigiosas organizaciones a nivel
nacional, como la Escuela Acadmico Profesional de Administracin de Negocios
Internacionales de la Universidad Nacional Mayor de San Marcos, la Facultad de Ciencias
Administrativas de la Universidad San Martn de Porres, la Organizacin Latinoamericana de
Administracin, entre otras reconocidas instituciones.


XITO BUSSINES AWARDS


Latin Business Organization plante dentro de sus principales actividades, el galardonar la
valenta de aquellas personas que apostaron por sus sueos y que de manera directa
contribuyen al crecimiento econmico de su pas a travs de la actividad empresarial que
desarrollan.
A travs del Premio Internacional Exito Awards la directiva de la organizacin convoca a
importantes entidades como universidades, instituciones, gremios y colegios empresariales de
la regin para patrocinar y respaldar al comit evaluador, el cual se encarga de realizar
estudios tcnicos, evaluar postulaciones, as como analizar y calificar las diferentes categoras
consideradas. (Industria, Comercio, Servicios, Salud, Turismo, Comunicaciones, Informtica,
Educacin, Gestin Pblica, Responsabilidad Social y Filantropa).
De esta forma, mediante este importante reconocimiento se difunden los casos empresariales
que en merito a su excelencia, compromiso, valor, creatividad, innovacin, ayuda social,
prestigio y calidad han logrado contribuir a la generacin de empleo y al desarrollo econmico
de su sociedad a nivel Iberoamericano y que los conducen por el arduo sendero del xito
Empresarial.
PATENTES

BIOPROTEIN COLUSTRUM

Food supplement having high immunological value,
based on a protein matrix
WO 2013009194 A1
RESUMEN
The invention relates to a food supplement having high immunological value, based on a protein
matrix, i.e. a food compound with high immunological value, based on the mixture of four
protein sources: i. biotechnologically improved bovine colostrum; ii. egg albumin; iii. soy protein
isolate; and, iv. concentrated whey protein.
RECLAMACIONES traducido del espaol (El texto procesado por OCR puede contener
errores)
1. Bionutricional a protein compound soluble in water, comprising, in% by weight: a. Up to
6.17% soy protein isolate;
b. Up to 76.29% egg albumin;
c. Between 17.04% of whey protein concentrate, and
d. 0.5% bovine colostrum protein concentrate biotechnologically improved.
DESCRIPCIN traducido del espaol (El texto procesado por OCR puede contener
errores)
FOOD SUPPLEMENT IN HIGH VALUE UNOLGICO. BASED ON A
MATRIX PROTEIN.
1. TITLE OF INVENTION:
High dietary supplement immune value, based on a protein matrix.
Two. TECHNOLOGY SECTOR:
The invention relates to a food composition immune high value, based on the mixture of four
protein sources (i. Bovine Colostrum biotechnologically improved ii. Egg albumin iii. Isolated
Soy Protein, and iv. Concentrated Protein whey).
Three. PREVIOUS TECHNOLOGY:
Within the spectrum of nutritional supplements currently available, find products of different
brands and backgrounds, who have different qualitative features as immunostimulatory
capacity, high bioavailability (chemical score) and digestibility, but none of them are in a fusion
of these features.
Examples: 3.1 We conducted an information search technology based on the elements "soy /
milk / egg / whey" and "I / milk / egg whey" resulting in 14 patent applications, obtained from the
following sources:
- Database of the European Patent Office
- Database of Spanish Office of Patents
- Database Patent Office U.S.
- Database of the Directorate of Inventions and New Technologies of Peru
The results of the search at the end of the present specification as Table 1. In this regard, we
conclude that the search conducted was not found a history similar to "high-value feed
supplement immune, based on a protein matrix." 3.2 Also in our market we have found the
following products based on a single source of protein, based on some combination of them or
some source of protein combined with Bovine Colostrum. None of them has the unique
combination of Bioprotein + protein nor a base value of 100% Organic: a) 4Life (Tri-Factor
Formula): Capsules and drinks as transfer factors provide immune system support.
b) 4Life (Transfer Factor E-XF): Factor Capsule Bovine Colostrum transfer combined with egg
yolk protein.
c) 4Life (Extract Nano factor) nano capsules extract Bovine Colostrum factors.
d) Herbalife (Frmula-!) nutritional shake with isolated soy protein, vitamins and minerals.
e) Herbalife (Formula 3): Supplement based protein soy protein isolate.
f) Omnilife (Super Mix): based nutritional smoothie whey protein, soy protein, calcium caseinate,
vitamins and minerals.
g) Naturavit: colostrum capsules with improved properties of the immune system.
h) Nature's Sunshine Products (SynerProTein): Protein supplementation with soy protein,
essential amino acids, vitamins, minerals and fiber,
i) Nature's Sunshine Products (Colostrum Plus): a combination capsules of colostrum, nositol
and herbal elements to nourish and support the immune system. j) Lab Mead Johnson
(Sustagen): Nutritional supplement with milk protein (WMP), vitamins and minerals.
k) 80/40 (Hyper Immune Colostrum) colostrum capsules with 40%
Immunoglobulin G, immune stimulant low in casein and lactose.
I) Tegor Sport (Tri-Matrix): Combination of whey proteins ("whey protein"), egg protein
(caseinate) milk, slow assimilation.
m) Aminostar: Powder Supplement whey protein, casein, egg protein, supplemented with
essential amino acids, vitamins and minerals for assimilation during sleep at night,
n) ProWinner Supplement powder soy protein concentrate supplemented with stimulating
hormone (soy isoflavones), with a chemical score of 61%. o) Intact Colostrum powder with high
protein profile.
p) Mervick Supplement powder, combination of whey protein and egg protein for athletes. q)
Pulver (ainer, uvoaiDumin nusj: Powder Supplement, comoinacion proieina ae ae egg and
whey protein, muscle builder,
r) Core: Supplement powder, combination of milk protein (caseinate), whey protein, collagen,
whey protein hydrolyzate, decaffeinated coffee, vitamins and minerals. To strengthen and repair
joints for athletes and to promote growth and weight gain.
April. DESCRIPTION OF THE FIGURES
Figure 1 shows a picture Comparative Biological Value of Proteins commonly used in human
food.
Figure 2 shows a Comparative Table Bioprotein Biological Value + versus other proteins
commonly used in human food.
Figure 3 shows a graphical representation of different protein sources
and limiting amino acids.
Figure 4 shows a graphical representation of the amino acid supplementation of different protein
sources.
Figure 5 shows a representation of the amino acid sequence of a protein.
May. EXPLANATION OF THE INVENTION
An analysis in the previous section dietary supplements currently available, we found that a
group of them ("colostrum", "transfer factors") are run by one side to enhance innate immunity
and resistance of healthy people, and on the other to help them combat certain diseases, while
other compounds are aimed at providing the body rapidly assimilated protein to improve the
quality of nutrition, growth and even induce, for proper muscle development practitioners sports.
Our premise to develop an alternative formula, part of an obvious gap to date. When it comes to
immunity, it is important to note that not just boost the immune system through the use of
various biological agents, but also that this stimulation must find adequate support in the
nutritional status of the individual, which plays an important factor in the performance of our
defenses. This is corroborated by the simple fact that the main molecules involved in immune
defense (immunoglobulins) are proteins. Therefore, very little will stimulate immunity in
convalescents and weakened by disease, or chronic undernourished, because the
responsiveness of your system immunology) is weakened.
Against this background, the compound called "Bioprotein +" is intended to significantly improve
the immunity of the consumer, whether sane or illness, as it provides immunoglobulins and
transfer factors, both stimulatory immunological vehiculizados a protein compound
bionutricional that provides nutritional support for proper immune system response.
Bioprotein + is the result of the combination of colostrum biotechnologically improved (with a
concentration of immunoglobulins five times greater than that of human breast milk and transfer
factors), with a protein food maximum digestibility obtained from three different sources: egg
albumin , soy protein isolate and whey protein concentrate.
Then proceed to detail the stages of the production process Bioprotein +:
RECEPTION
OBJECTIVE: Receive, supplies, packaging materials that meet the requirements of
SAC PROLIFE quality BIOTECH
ACTIVITIES:
1. Front National inputs: Isolated Soy Protein, Albumin Egg Powder from the Temporary
Storage
Two. Receipt of Imported Inputs: Whey Protein Isolate Milk Protein Bovine Colostrum.
Three. Confrontation with purchase order.
April. Review and Quality Control sampling.
May. Spend a target store.
B. WAREHOUSE SUPPLIES
OBJECTIVE: Properly store the inputs are acquired and delivered production temporarily so
they do not lose their organoleptic, physico-chemical and microbiological and suffer no damage.
C. ADDITIVES AND PACKAGING WAREHOUSE PURPOSE: Properly store additives and
packaging materials are purchased so that either retain their organoleptic characteristics,
physico-chemical and / or microbiological and suffer no damage.
OBJECTIVE: This stage involves the weighing of inputs entering each batch.
ACTIVITIES:
1. Receiving input from the previous stage.
Two. Heavy input (fractions) according to the formula. (See Table No. 2 at the end of the
specification presnete)
Three. Sacks and was sent to the mezzanine heavy fractions mixing, respecting the batch.
April. At the end of the shift is performed returning the remaining inputs to the store manager.
MIXED
OBJECTIVE: The mixing consists of homogenizing all the ingredients according to the
formulation. This operation is performed while keeping an order of adding ingredients.
ACTIVITIES:
1. Inputs emptying the hopper of mezzanine which connects through a screw to the surge
hopper of the mixer.
Two. Opens the discharge valve of the hopper to fill the mixer.
Three. Mixing time after the machine is discharged through a discharge control screw.
April. All equipment feed hopper, hopper mixer lung and are constructed of stainless
steel. HEAVY-PACKAGING (BULK)
OBJECTIVE: Remove the mixture homogeneous bulk weight.
ACTIVITIES:
1. The discharge from the mixer is realized in kraft paper bags with polyethylene inner
appropriately coded.
Two. Each bag is weighed, then placed the seal and stitched bag
Three. Product is removed for temporary storage. G. TM IUI ALMAUENAMItlM UHAL
OBJECTIVE: The delivery of finished products in bulk to the temporary storage for later use
ACTIVITIES:
1. Location armed stretchers the buffer
Two. Identifying each parihuela
To better understand the process carried out is attached to the end of the present specification
the corresponding flowchart.
In order to achieve maximum chemical score and maximum bioavailability (100%) have used a
mathematical model for the combination of the three protein sources. This model, called "linear
programming" has enabled us to perform simulations of the combination of different proportions
of protein compounds involved according to their contribution of amino acids (remember that the
critical factor for a higher bioavailability of 99.99% is the limiting amino acid or lower
concentration, which must be supplemented by other sources) to determine the exact
proportions that allow a perfect amino acid complementation between them.
As a result of applying the model of "linear programming" bionutricional got a compound soluble
protein, consisting of (% by weight): a. Up to 6.17% soy protein isolate, b. Up to 76.29% of egg
albumin, c. Between 17.04% of whey protein concentrate, and d. 0.5% bovine colostrum protein
concentrate biotechnologically improved.
Testing the optimal amino acid supplementation, the is the CHEMICAL COMPUTER
CERTIFICATE No. 0607-2008 issued for Bioprotein + by SAC Technical Advisory Company,
located at the end of the present specification and shows how the limiting amino acid "lysine
"with a value above 100%, concluding that" exceeds the minimum specification Bioprotein
99.99% Chemical Computation ".
Another important factor Bioprotein +, is its presentation as a very pleasant flavor milkshake,
since the compounds presented in dosage forms (capsules, tablets) are generally subject to
prejudice and rejection by the average consumer. By contrast, a with saor agraaaoie Datiao
pueae generate naoito ae saiuaaDie Denegaos consumer health ios described above.
Colostrum 5.1 CATTLE AND TRANSFER FACTORS:
Colostrum is the first substance secreted by the mammary glands of any mammal, including
humans, after delivery. This is a process of very short duration (24-96 hours post partum).
Scientific research in the late 90's, have shown that the combination of growth factors and
immune bovine colostrum is virtually identical to the human colostrum and colostrum is not
"species-specific", ie it works effectively in humans as well as other mammals.
Recent studies have also shown that once past puberty, the human body gradually produces
less immune and growth factors, important to prevent disease and heal damaged tissues in the
body. With the loss of these vital components, we age until finally we die. Colostrum is the only
natural source of these vital components.
Bioprotein + is an important source of immune factors mentioned supplemented with protein
intake by way of nutritional support, which ensures its action on the human body.
5.2 TRANSFER FACTORS:
The immune system is the largest human defense against disease. A disease generally
indicates that our immune system is weakened and failed. This may be due to poor diet,
pollution, chemicals, stress, exposure to electromagnetic radiation, and many other factors that
we face daily. Transfer factors are small peptides, composed of 40 amino acids, which store all
the experience of the immune system. These amino acids function as the twenty-six letters of
the alphabet. When in contact with a seed, storing the characteristics of that particular germ,
changing the sequence of amino acids. Transfer factors are the "intelligence" of the immune
system. They are vital to the defense against invading germs and diseases. Ie transfer factors
stored information relevant to the human being relative to viruses, bacteria, fungi and parasites
which have attacked in the past. This information is then transferred to certain immune system
cells, which will defend the attack of such viruses, bacteria, fungi and parasites.
Transfer factors also mobilize the cells called "natural killer" ("natural killer") and directed
against cancer cells. Moreover certain components of transfer factors modulate the immune
system to prevent it from attacking the body itself and cause disease autoimmune diseases,
such as rheumatoid arthritis, lupus, and other conditions.
5.3 PROTEIN:
The proteins constitute about 75% of the solid body and can be structural proteins, enzymes,
hormones, oxygen transport proteins, proteins of muscle contraction and others that perform
specific functions in and out of the cells (See Figure 5) . In turn, twenty amino acids involved in
protein synthesis in living organisms. Of the twenty amino acids, nine are essential and should
be included in the diet, two are semi (especially in childhood, in adulthood are relevant to stress
and disease) and nine non-essential.
These twenty amino acids are: Essential: isoleucine, leucine, valine, lysine, methionine,
phenylalanine, threonine, tryptophan and histidine.
semi: They are synthesized from amino acids. Are tyrosine is synthesized from phenylalanine,
and cysteine, synthesized from methionine. Nonessential: alanine, arginine, asparagine,
glutamic acid, glycine, proline, hydroxyproline and aspartic acid.
Amino acids derived from the digestion, which releases them from ingested proteins. Then the
free amino acids are absorbed by an active process. Animal protein digestibility have close to
100%, and the plant 70 to 80%. 5.4 BIOLOGICAL VALUE OF PROTEIN:
Is given by: The content of essential amino acids
Your digestibility
The use of them to make the human body
This is important because the quality of the protein of food depends on its content of essential
amino acids. In this regard, FAO has indicated that a protein is biologically complete when it
contains all essential amino acids in an amount equal to or greater than that established for
each amino acid in a reference protein or pattern. 5.5 COMPUTATION amino acid:
Proteins possessing one or more limiting amino acids, that is found in a lower proportion than
that provided by the reference protein or pattern, are considered biologically incomplete
because it does not fully used. The ratio of the limiting amino acid found in a lower proportion
compared with the same amino acid in the reference protein, amino acid called computer (CA).
The plant foods such as legumes and cereals constitute a significant percentage of dietary
protein, but both have limiting amino acids that decrease the efficiency of their use and need to
be complemented with others to improve their quality. This can be achieved by adding small
amounts of animal protein or a combination of them, since legumes are low in sulfur amino
acids (methionine + cystine) and cereals such as wheat, rice, corn, are low in lysine (corn also
is low in tryptophan and rice threonine). To be the limiting amino acids different legumes and
grains, a mixture of both amino acid will improve the counting and thus the biological quality of
the protein mixture, amino acid process called complementation.
5.6 QUALITY OF DIET:
FAO and WHO have stressed the importance of measuring the quality of dietary protein (amino
acid score - CAA -, digestibility) consumption and biologically complete proteins because they
are related factors and diet quality that deserve to be taken into account when designing a diet
with a certain amount of protein for the population
'1, 2).
These factors, properly handled in the
daily diet, should guarantee consumers the refund of 100% of labile body protein and allow
100% regeneration of the cells of our body.
In the case of absence of experimental data digestibility of dietary protein or protein sources
which constitute it is suggested to use a value of 85% for digestibility diets consist primarily
those plant foods and 95% for those who are content with a high percentage of refined grains
and animal foods. However, in the first case we see a deficit of 15% and the second at 5%,
which promotes gap further deterioration of the cells in our body.
June. TECHNICAL PROBLEMS THAT ARE SOLVING:
1. Supply of transfer factors and immunoglobulins in the daily diet. The human being is better
immunized breastfeeding stage, given the contribution, first transfer factors from colostrum and
immunoglobulins after, breast milk. At the end of lactation, also ends as providing important
immune factors, which will never be recovered. Bioprotein + is an alternative food which again
allows access to so important nutrients in the form of a milkshake daily consumption.
Two. Refund 100% of labile body protein (100% cell regeneration).
To date, to make a contribution amino acid and biological value approximate daily protein
requirements of human nutrition, the only alternative was the combination of different protein
sources, without implying a refund at 100%, ie complete cell regeneration.
This practice also represents other additional constraints for the average consumer, such as
lack of food types most suitable for combined or the exact proportions of the same for its
effective amino acid supplementation. Bioprotein-h in protein sources (i. improved biologically
Bovine Colostrum ii. Egg albumin iii. Isolated Soy Protein, and iv. Whey Protein Concentrate)
were combined in proportions to provide a bioavailability of 100 %, ie the body guaranteeing
100% refund of labile body protein and thereby allows 100% regeneration of the cells of our
body. + Called Bioprotein compound is a food bionutricional immunological capacity and
nutraceutical unique worldwide.
References 1. aidad hvaiuacin protein and its ingestion and ios Essential Amino Acids in
Pregnant Group. Aliment Cuban Rev Nutr 2000; 14 (1) :28-32.
Two. Balance of Protein Animal and Plant of the Chilean diet. Hundred. Inv.
Agr. 31 (3): 145-154.2004.
July. FIELDS OF APPLICATION OF A HIGH VALUE FOOD SUPPLEMENT IMMUNE BASED
ON A MATRIX PROTEIN (Bioprotein +) IN THE
HUMAN NUTRITION:
Colostrum is the first liquid produced by the mammary glands of the mother within the first 24-48
hours after birth the baby.Colostrum provides immune and growth factors essential for life to
ensure the health and vitality of the newborn. Colostrum is so important that most babies of any
animal would die if they could not take it.
After puberty our body begins to slowly reduce its production of growth hormone, necessary for
the reproduction of virtually all cells and tissues of our body. It has been shown that at age 80
years, virtually do not produce growth hormone and hence, from this moment we die rapidly
age. Growth factors from colostrum are indeed hormones that stimulate normal cell tissue
reproduction. The normal cell reproduction means slow aging and cancer prevention, wrinkles
and general weakness.
A few years ago I heard The New England Journal Medicine said that growth hormone
supplement to more appropriate levels could slow the process of aging, and possibly stop them.
7.1 VALUE HIGH DIETARY SUPPLEMENT IMMUNE (Bioprotein +) IN DISEASE
PREVENTION
The beginning of almost all diseases, whether infectious or degenerative diseases, including
cancer and heart disease, is preceded or accompanied by a decrease in immune system
function. Studies show that colostrum contains powerful factors (immunoglobulins, lactoferrin,
cytokines and interferon) that repotencian immune reaction. Herein lies another advantage of
ProLife Bioprotein +. Colostrum used in the formulation has a content of immunoglobulins (IgG)
five times higher than that of human colostrum. Colostrum contains you tamoien (eptiaos
hICOS Proline), which according to medical studies, help strengthen the immune system
hypoactive, especially when your biodisponibidad is 100%. The PRP thymus help restore the
optimum operating capacity. This gland produces virus-fighting T-lymphocytes and
antigens. The PRP is found in colostrum also help stabilize the hyperactive immune system that
is in autoimmune diseases. This makes the colostrum is extremely effective against diseases
such as chronic fatigue syndrome, fibromyalgia, multiple sclerosis, rheumatoid arthritis, lupus
and scleroderma.
7.2 VALUE HIGH DIETARY SUPPLEMENT IMMUNE {Bioprotein +) INCREASE IN MUSCLE
MASS AND BODY WEIGHT CONTROL
According to some publications colostrum serious about bodybuilding is extremely powerful in
generating muscle mass, when accompanied by appropriate exercises.
Research has shown that humans easily assimilate colostrum, especially if it has a suitable
chemical computation. It is also known that only bovine colostrum contains glycoproteins and
protease inhibitors that are highly effective in protecting the active components of colostrum
against the destructive effect of digestive enzymes and stomach acids of adult human.
According to Dr. Robert Preston of the National Institute of Nutrition Research USA, "Colostrum
is so safe that has been made by nature as the first food for infants. Would be difficult to
imagine a more natural nutrient or beneficial ".
7.3 VALUE HIGH DIETARY SUPPLEMENT IMMUNE {Bioprotein +) IN INTESTINAL
PERMEABILITY
Intestinal permeability (leaky gut syndrome) and irritable bowel syndrome occur mostly because
the bowel has been exposed to infectious agents such as bacteria, viruses, fungi (Candida),
parasites and various toxins. There are other causes as well, including poor diet, drinking
alcohol, anti-inflammatory drugs, cytotoxic drugs and bodily stress reactions to situations such
as heart attacks, surgeries, and any other form of shock. This condition can lead to many
problems that are common, such as diarrhea, poor absorption of food, and food allergies. It is
also often associated with more serious conditions, such as Crohn's disease. Furthermore
intestinal symptoms of this type are often a component of many severe autoimmune diseases
such as muscular dystrophy, fibromyalgia and scleroderma. e fact, many doctors believe that
most illnesses originate in the intestines.
Studies show that colostrum can stop leaky gut syndrome, with its unique combination of
immune and growth factors that appear to have been tailored by nature as a remedy against
this disease. Immunoglobulins (IgA, and IgM IgF), lactoferrin and other immune factors can
inhibit reproduction of invading pathogens (infection), and protect against toxins. Epithelial
growth factor from colostrum stimulates intestinal membrane repair cellular
level. Antiinflammatory action raises cell spacing decreases, thereby reducing the
hyperpermeability.
Because of Bioprotein colostrum + decreases intestinal permeability and high bioavailability
assimilation greatly increases also increases the efficacy of all other nutrients consumed in a
normal diet.
7.4 VALUE HIGH DIETARY SUPPLEMENT IMMUNE (Bioprotein +) IN ARTHRITIS AND
AUTOIMMUNE RESPONSE
Arthritis almost always accompanied by inflammation. The inflammation and pain that
accompanies it, in fact, a mild form of autoimmune disease or poor performance. It is the result
of the attack initiated by the immune system to antigens after this response is no longer
needed. Many more serious autoimmune diseases such as muscular dystrophy (Lou Gehrig's
disease) and scleroderma also derived from an overactive immune system.
Recent studies have shown that natural compounds containing sulfur, such as glucosamine
sulfate, have a beneficial effect on inflammation, especially arthritis. Colostrum is an excellent
source of these micronutrients containing sulfur, including the "MSM", or
methylsulfonylmethane, also has garnered much international attention lately. In fact, colostrum
is one of the richest sources of MSM is known. Also has other powerful components, including
two of the most potent anti-inflammatory compounds. This gives far more anti-inflammatory
potency than the sulfur compounds alone. 7.5 EFFECTS OF Colostrum 100% BIOAVAILABLE
(Bioprotein +) IN OSTEOPOROSIS
Studies show that transforming growth factor (TGF) in colostrum can help prevent
osteoporosis. Osteoclasts are cells that dissolve nueso undermining its structure and producing
porosity and loss of bone strength is called osteoporosis.Osteoblasts, moreover, are the cells
that build bone. With aging, the number of osteoblasts and osteoclasts decreases
increases. This is especially true in postmenopausal women, since it has been shown that a
decrease in estrogen levels causes an increase in the number of osteoclasts.
Natural Medicine a study demonstrates that the TGF-B which is in its natural form only in
colostrum, also is naturally produced by the osteoblasts. The study also shows that TGF-B
dramatically increases apoptosis (cell death) between osteoclasts. The study indicates that
TGF-B may reduce the risk of this disease.
7.6 VALUE HIGH DIETARY SUPPLEMENT IMMUNE (Bioprotein +) MUSCULAR
DEVELOPMENT
According to clinical studies, colostrum may be the most powerful natural substance has been
found to help athletes get the results they want.
In fact, many bodybuilders and trainers experts say that colostrum is the agent most effective
muscle development they have ever used.
In his article in Ironman (certified and specialized magazine for bodybuilders), Daniel Shawn,
declares that LGF-1 growth factor (insulin-like) found in colostrum "has greater anabolic effect
than any known compound, even steroids. "
LGF factor-1 can "promote muscle growth alone," writes Steve Schwade, deputy editor of
Muscle & Fitness, in its issue of May 1992. "Bovine colostrum having a concentration of LGF-1
higher than human colostrum," he continues, "and its structure is virtually identical. LGF-1
human and bovine LGF-1 differ only in three of the 67 amino acids that make up the molecule of
this factor. Due to this similarity, bovine LGF-1 is as potent as the human. "
Mr. Schwade continues to cite current studies have demonstrated that colostrum causes the
breakdown of protein occurs more slowly and "... stimulates the transport of glucose into
muscle," which means the muscles can be used more efficiently the nutrients that are
available. /. / BU Lb ALIMbl I tN UI AL UI VALUH IUIU IINMUNULU1UU Ut ( +)
folliculin tL
WEIGHT
If we have to talk about fat metabolism, growth factors in colostrum "cause switch from using
carbohydrates to use fat. This does not mean you can eat more fat, but it does mean that the
body can burn more, including manufactures body fat from carbohydrates and protein you eat,
and thus more efficiently produce fuel cell, "continues Mr. Schwade.
And to conclude: "In summary, the growth factors (in colostrum) accelerate and decelerate
protein synthesis catabolism (the breakdown of protein) which leads to an increase in lean
muscle mass without a corresponding increase in the adipose tissue. "
And now again Daniel Shawn, of Ironmarr. "Plain and simple LGF factor-1 is the non plus ultra
of growth factors anabolic peptide compounds."
7.8 VALUE HIGH DIETARY SUPPLEMENT (Bioprotein +) IN SPORT
Recently there have been more studies with athletes. In his article in Nutrition Science News
May 1996, Dr. Edmund Burke, reports on research done with the Finnish Ski Olympic
Team. "The athletes were training very hard and were analyzed creatine kinase levels in seven
days. Muscle enzyme creatine kinase is critically important that has been proven is a sign of
damage to muscle cells is detected in the blood. Therefore when creatine levels rise, it is often
an indication that there has been a significant muscle damage compared to team members who
took placebos, athletes who consumed a drink made with colostrum had only about half of the
rise in creatine kinase levels four days after fatiguing exercises have done. " On the subjective
side, the athletes also said they felt less fatigued and I thought his performance improved.
Burke In the same article goes on to say that colostrum also "enhances athletic performance
through the gut". Colostrum increases nutrient assimilation through these and thereby improves
the efficiency of the absorption of carbohydrates and amino acids. Similarly, the growth factors
in colostrum, "sealing" digestive tract and protect against ulcers, which would reduce the
efficiency of absorption. So we colostrum cuanao happens is that more nutrients from food ia
ae fuel can be used for exercise, whether the type of cardio or bodybuilder.
August. INVENTIVE:
As we mentioned in the specification, natural proteins show a significant limitation in its
Biological Value (BV), with whey protein ("whey protein") which according to FAO, shows the
highest VB: 95% (Figure 1).
On the other hand, although the colostrum has a very complete amino acid profile and
demonstrated positive health effects, does not achieve a bioavailability of 100%. The constant
concern of doctors, nutritionists and other health professionals has been to find or make a
compound naturally occurring protein, administered parenterally, allow the body protein
metabolism to ensure 100% refund of labile body protein and allow to This 100% regeneration
of the cells of our body. If to this we add him collaterally a promoting effect of health, we would
be facing a nutraceutical functional food capabilities unique in the world.
To illustrate this point, in Figure 3 have shown various protein sources such as a glass, and its
limiting amino acid as a hole, also see respective values of VB. If everyone had the ability to fill
to the brim, cell regeneration would be 100%, that's 100% bioavailability. The "limiting amino
acid" causes the protein to lose the ability to fill to the top and get to that 100% bioavailability.
Our starting point was on the assumption that by combining different sources of protein, a
limiting amino acid may be supplied in sufficient quantity on the other. In Figure 4 we plotted
juntramos this premise as if the four vessels. Each would plug the hole in the other, so that
there would be "leaky" and the limiting amino acid would reach 100% Chemical Computing
(bioavailability).
According to the medical evidence available, a colostrum with chemical score of 100% human
organism can provide the following benefits:
> Regenerate and accelerate the normal growth of muscle tissue, bones, cartilage, skin
collagen and nerve tissue. p ia help burn fat instead utmzanaoia as comDustiDie tejiao ae ei
muscle use in times of fasting (and diet).
> Help develop and maintain lean muscle tissue.
> Repair body's genetic material: DNA and RNA.
> Stabilize and regulate blood sugar levels. Control infection and pain associated with gingivitis,
sensitive teeth and dental work.
> Helping to regulate glucose levels in the blood and brain chemicals that keep us on alert and
we facilitate concentration.
> Helping to regulate the chemicals that give us the feeling of comfort and we elevate mood.
TABLE NO. 1



FLOWCHART
PRODUCTION PROCESS OF Bioprotein +
Isolated Soy Protein
Egg Albumin Protein Whey Protein Isolate Dairy (IWPC)
RECEPTION Protein Bovine Colostrum (50% IgG)
Aminogen enzyme complex
WAREHOUSE WAREHOUSE PACKAGING SUPPLIES
HEAVY INPUTS
MIXED
HEAVY -
TEMPORARY STORAGE
Table No. 2. LIST OF INGREDIENTS: Bioprotein +

SAC Technical Advisory Company

COMPUTER GIVE CERTIFIED CHEMICAL No. 0607-2008
APPLICANT DATA deti!
NAME OF APPLICANT: BIOTEC PROLIFE S.A.C.
ADDRESS: Calle Camino Real ti * 1801 Interio D-2 - Santiago de Surco - Lima
CERTIFICATION SYSTEM-N ". 1 (Type or Prototype)
PRODUCT DATA
PRODUCT Bioprotein
BRAND NO BRAND
CONTAINER Piitiieno bag without litografiar x 500g.
Bioprotein PRODUCER NAME REFERENCE DOCUMENT certifications
Technical specifications ef Provided by Customer.
Computing least 99.99% of Qulmiqp:
GIVE TEST METHODS AND QUALITY NEEDS GIVE NUTRIGIONALS DIET. INSTRUCTION
MANUAL AUTO SONIA OLIVARES et al, UNIVERSITY OF CHILE. TA N 199.4
RESULTS According Test Report No. 004-2008

CONCLUSIONS:
From theoretical calculation agrees ai, Limiting Amino Acid: Lysine Product Bioprotein exceeds \
a minimum specification of 99.99% Chemical Computation.

CITAS DE PATENTES
Patente
citada
Fecha
de
present
acin
Fecha
de
public
acin
Solicitante Ttulo
CN1018285
98A *
13 May
2010
15 Sep
2010

Health-care
food for
improving
human
immunity
EP0391416
A1 *
5 Abr
1990
10 Oct
1990
Chugai Seiyaku
Kabushiki Kaisha
Process for
preparing a
Patente
citada
Fecha
de
present
acin
Fecha
de
public
acin
Solicitante Ttulo
therapeutic
agent for
rotavirus
infection
ES2155855
T3 *
Ttulo no
disponible
ES2166084
T3 *
Ttulo no
disponible
ES2346912
T3 *
Ttulo no
disponible
FR2811204
A1 *
Ttulo no
disponible
JP20031378
08A *
Ttulo no
disponible
SU1531948
A1 *
Ttulo no
disponible
US2003000
8016 *
2 May
2002
9 Ene
2003
Crum Albert B.
Prophylactic
and
therapeutic
nutritional
supplement
for
creation/main
tenance of
health-
protective
intestinal
microflora
and
enhancement
of the
immune
system
US2006012
7454 *
4 Nov
2003
15 Jun
2006
Coloplus Ab
Feed or food
product
composition
US2006028
0840 *
24 May
2005
14 Dic
2006
Robertson Marion G
Universal
protein
formulation
meeting
multiple
dietary needs
for optimal
Patente
citada
Fecha
de
present
acin
Fecha
de
public
acin
Solicitante Ttulo
health and
enhancing the
human
immune
system
* Citada por examinador
OTRAS CITAS
Referencia
1 *
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1990-
326426 & SU 1 531 948 A (GORSK AGRIC INST) 30 December 1989
2 *
DATABASE WPI Derwent Publications Ltd., London, GB; AN 2003-
674219 & JP 2003 137808 A (KAKUNAI JUYOTAI KENKYUSHO KK)
14 May 2003
3 *
DATABASE WPI Derwent Publications Ltd., London, GB; AN 2010-
M89128 & CN 101 828 598 A (SHANDONG SENJIAN
BIOLOGYTECH DEV CO LTD) 15 September 2010
* Citada por examinador
CLASIFICACIONES
Clasificacin
internacional
A23J1/14, A23J1/20, A23J1/08
Clasificacin
cooperativa
A23J1/14, A23J1/08, A23J1/20, A23L1/3056, A23L1/3053
EVENTOS LEGALES
Fecha Cdigo Evento Descripcin
6 Mar 2013 121

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