Pathogenicity of organisms.
I. Vitamin
Deficiency
A ) fat soluble Vit.
(1) Vit. A Diffeciency
Function:
maintain the health of epithelial cells of the skin and
m.m.
responsible for re-epitheliazation as epithelial tissues
provide a protective barrier against invading micro-
organisms
Function:
absorption of calcium from GIT .
maintainer of calcium phosphorus balance
Function:
absorption of calcium from GIT .
maintainer of calcium phosphorus balance
(2) Vit. E
Function:
anticxiddant to limit the free radical reaction .
protect cells from peroxidation .
(1 ) vit, B complex:
Thiamin.
Riboflavin.
Niacin.
Pyridoxine (B6).
Biotin.
Folic acid.
Cobalamin (B12).
oral diseases rarely accure due to diffeciency in one
component but diffeciency is generally multiple
Complications
Microvascular Macrovascular
1. Retinopathy. 1. Cardiovascular.
2. Neuropathy. 2. Cerebrovascular
3. Nephropathy
insulin dependent diabetes.
Preceded by obesity
Gingiva:
inflamed.
enlargement either localized or generalized.
sessile or peduncualted gingival p lips.
Types:
1) Pernicious anemia :
Tongue atrophy red , smooth and shiny appearance .
pallor gingiva .
Idiopathic thrombo-cytopenic
purpura, petechiae and
ecchymoses of the buccal
mucosa.
V. Psycosomatic
disorders
It affect the oral cavity by :
1) development of habits that are injures to the
periodontium as grinding or clenching the teeth,
nibbing on foreign objects as pencils, nail biting of
excessive use of tobacco gingiaval recession and
periodontal diseases .
Agranulocytosis, mild
periodontal destruction.
AIDS:
Etiology :
• human Immuno deficiency virus .
Effects:
• Destruction of lymphocytes increase susceptibility to
opportunistic infections including destructive
periodontitis and malignancies .
VII. Other Systemic
Diseases
Bismuth intoxication:
It will lead to
GIT disturbances, Nausea, Jaundice.
Lucrative gingivostomatitis with pigmentation.
Metallic taste.
Burning sensation of the mucosa .
Inflamed sore tongue .
Erythromatous eruptions of different types and hyrpes
zoster like eruptions of the skin and m.m.
Narrow bluish black discoloration of the gingiaval
margin due to precipitation of bismuth sulfide
associated with vascular changes in
inflammation of the gingiva .
Lead in toxication :
It will lead to :
pallar of face and lips .
GIT disturbances including nausea , vomiting , loss of
apetite and abdominal colic .
Peripheral neuritis, psycologic disorders and
encephalitis .
Excessive salivation .
Coated tongue .
Sweetish taste.
Gingival ulceration and pigmentation (Linear
pigmentation in burtonian line, Steel gray )
Mercury in toxication :
It will lead to :
Headache .
Isornnia .
C.V.S. sympioms .
Increase salivation .
Metallic taste .
Giugival pigmentation in liner pattern due to mercuric
sulfide.
Gingival ulceration and destruction of the underlying
bone.
Other chemicals :
Include :
Phosphorus .
Arsenic .
Chromium .
It will lead to :
Inflammation and ulceration of the gingiva .
Necrosis of alveolar bone and loosening of teeth .