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LSM1302/GEK1527
LSM1302/GEK1527 Self-Assessment Q's Section II AY13-14 Sem I
Student : 025442 (dbsgl)

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Generated on 04-Sep-2013 11:27 AM by Gapter, Leslie (dbsgl)

Section 1
1) The natural process of exchanging regions of DNA between paired chromosomes during meiosis I is also known as:
inversion
homologous recombination
mutation
transposition
translocation
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2) You have an diploid organism and find that it has 12 chromosomes in its gametes.
Assuming sex is determined as it is in humans, how many total autosomes are there in the somatic cells of this organism?
12
10
24
22
6
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3) Choose which option below contains all of the enzymatic activities that are REQUIRED for nucleotide excision repair:
DNA glycosylase, 3' to 5' exonuclease, DNA polymerase, DNA ligase
endonuclease, DNA glycosylase, DNA polymerase, DNA ligase
helicase, 3' to 5' exonuclease, DNA polymerase, DNA ligase
3' to 5' exonuclease, endonuclease, DNA polymerase, DNA ligase
helicase, endonuclease, DNA polymerase, DNA ligase
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4) Which of the following is/are TRUE regarding translation?
I. In eukaryotes it occurs in the cytoplasm.
II. In prokaryotes it occurs in the cytoplasm.
III. Both eukaryotes and prokaryotes can have polyribosomes.
IV. In eukaryotes and prokaryotes it occurs only when the mRNA is completely transcribed and processed.
I, II, III and IV.
I, II, and III only.
I, II, and IV only.
I and II only.
III and IV only.
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5) The ingredients needed for translation include:

primase, RNA polymerse, mRNA, ribosome, amino acids
RNA polymerase, ribosome, amino acids
RNA polymerase, mRNA, ribosome, tRNA, amino acids
mRNA, tRNA, ribosome, amino acids
DNA polymerase, mRNA, ribosome, amino acids
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6) Proto-oncogenes are genes that code for proteins that normally
cells to progress through the cell cycle;
cells from progressing through the cell
while tumor suppressor genes code for proteins that normally
cell growth and
cycle. When one allele of a proto-oncogene is mutated in a cell, the cell will have
division.
promote; prevent; normal
prevent; promote; normal
none of the options is correct
promote; prevent; abnormal
prevent; promote; abnormal
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7) Different properties of amino acids are due to differences in their:
Charges and sizes
Charges
Central carbon atoms and charges
Sizes
Central carbon atoms
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8) A virus that infects bacteria is known as:
a plasmid
an adenovirus
a bacteriophage
a retrovirus
a mitochondria
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9) Using the list of characteristics below, choose which options are TRUE when describing epigenetics or the epigenome:
i. certain epigenetic tags cannot be changed throughout an organisms lifetime.
ii. certain epigenetic tags can be changed throughout an organisms lifetime.
iii. an example of an epigenetic tag is phosphorylation.
iv. epigenetic tags can be added to histones or the DNA itself.

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i, ii, iii, and iv.

i and ii only.
i, ii, and iv only.
i, iii, and iv only.
i,ii, and iii only.
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10) Increased methylation of DNA in the promoter region of a gene will
compact or dense.
because the DNA is

the expression of the gene

methylation will also cause this effect.

decrease; less; co-activator

increase; more; histone
decrease; less; repressor
decrease; more; histone
increase; less; histone
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11) If during transcription, a single nucleotide is mistakenly copied to a different nucleotide (substitution):
The function or structure of the protein product will be changed.
The genotype and phenotype may be changed.
The genotype will be changed, but the phenotype may or may not be changed.
The structure of the protein product will be changed but the function may or may not be changed.
The function or structure of the protein product may or may not be changed.
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12) Which of the following organisms can use RNA as their genetic material?
bacterium
human
plant
none of the options is correct
retrovirus
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13) You have an diploid organism that has 6 chromosomes.
If non-disjunction occurs between one homologous pair of chromosomes during meiosis I, how many chromosomes are
found in the gametes at the end of meiosis?
Not enough information to determine.
Three chromosomes.
Either two or four chromosomes.
Either zero or six chromosomes.
Either two, three, or four chromosomes.

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14) Splicing of the mRNA:
Can occur in the nucleus or cytoplasm.
Occurs only in eukaryotes.
Occurs only in eukaryotes in either their nucleus or cytoplasm and can occur simultaneously during translation of the
mRNA.
Can occur simultaneously during translation of the mRNA.
Can occur simultaneously during translation of the mRNA and occurs only in eukaryotes.
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15) You have an diploid organism and find that it has 5 chromosomes in each of its gametes.
How many chromosomes are there in the somatic cells of this organism?
20
15
10
5
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16) Which of the following statements is/are TRUE when considering the human genome?
The entire genome contains less than 25,000 protein-coding genes, each of which has a known function.
Most of the DNA sequence contains information that directly codes for proteins.
The entire genome contains less than 25,000 protein-coding genes.
All genes have known functions.
Most of the DNA is made of genes that code for proteins with known functions.
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17) Coat color in certain species is controlled by multiple alleles. The order of decreasing dominance of these alleles in
cattle is as follows:
Black (B), buff (f), brown (r), and albino (b). What phenotypic ratios are observed from a Bb X rb cross?
2 black : 1 brown : 1 albino
all black
1 buff : 1 brown
2 black : 1 buff : 1 brown
3 black : 1 buff
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18) Which of the following statements is/are TRUE regarding genomes of various organisms?
I. Some of the largest genomes belong to plants and amphibians.
II. Less than 10% of the human genome codes for protein.
III. A plasmid is not a part of the bacterial chromosome.
III only.
I and II only.
II only.
I only.
I, II, and III.
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19) Choose which option below contains all of the activities that are needed for mismatch repair:
3' to 5' exonuclease, DNA polymerase
endonuclease, DNA glycosylase, DNA polymerase, DNA ligase
3' to 5' exonuclease, DNA glycosylase, DNA polymerase, DNA ligase
endonuclease, 3' to 5' exonuclease, RNA polymerase, DNA ligase
helicase, 3' to 5' exonuclease, DNA polymerase, DNA glycosylase
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20) Retroviruses are useful in gene therapy because:
I. It can deliver a gene into specific cell types.
II. It can help to integrate a gene into the cell's genome.
III. It can activate transcription/translation of specific genes in target cells.
IV. It has all of the information and components that are needed for making proteins from DNA on its own.
I and II only.
I, II and III only.
I, II, III, and IV.
II and IV only.
I, II, and IV only.
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21) A person is born with two extra sex chromosomes and has a genotype XXXY for the sex chromosomes.
How many barr bodies will there be in the somatic cells of this person?
three
two
one
none
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22) Cells in the G1 stage of the cell cycle:

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Are producing the components needed for the next stage in the cycle, mitosis or meiosis.
Are in a 'resting' or 'quiescent' stage of growth.
Have twice the amount of DNA when compared to a cell in the G2 stage and are producing the components needed
for the next stage in the cycle, mitosis or meiosis.
Have twice the amount of DNA when compared to a cell in the G2 stage.
Have just completed cell division.
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23) Which of the following are CORRECT when describing reverse transcriptase:
I. it synthesizes DNA using an RNA template.
II. it synthesizes RNA using a DNA template.
III. it doesn't require a template.
IV. It has 5' to 3' proof-reading activity.
V. it has RNAse activity.
I, II, IV and V only.
I, II and III only.
I, III, and IV only.
I and V only.
I and II only.
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9/4/2013 11:27 AM