ACUTE GASTROENTERITIS

Ingestion of fecally contaminated food and water

Direct invasion of the bowel wall

cytotoxin Released toxin Protein

Irritation and inflammation of the bowel endotoxin

Increased permeability of mucosal cell

Destruction of mucosal lining

Absorptive
malfunction Increase secretion of
CI and HCO3 ions in
Ulceration the bone
Digestive malformation

Bleeding Peristaltic movement Inhibition of Na

Excessive gas formation
rearbsorption

GI distention H2o is drawn into intestinal

lumen

Increase protein in the lumen

Frequent passage of loose

Metabolic acidosis Fluid and electrolytes
watery stool
imbalances

Serious fluid
Hypovolemic shock
volume deficits

Death
Signs and symptoms

Irritation and inflammation of the bowel

 Abdominal pain
 Fever
 Increase WBC

Bleeding

 Hematochezia
 Melena
 Hematemesis

Digestive malformation

 Muscle wasting
 Body weakness

GI distention

 Nausea and vomiting

 Flatus formation

Peristaltic movement

 Abdominal pain
 Hyperactive bowel sound

Serious fluid volume deficit

 Decrease urine output

 Poor skin turgor
 Dry mouth
 Dry skin
 Dry mucous membrane