DOI 10.1007/s11999-010-1339-z
Abstract
Background Child abuse represents a serious threat to the
health and well-being of the pediatric population. Orthopaedic specialists will often become involved when child
abuse is suspected as a result of the presence of bony
injury. Distinguishing abuse from accidental trauma can be
difficult and is often based on clinical suspicion.
Questions/purposes We sought to determine whether
accidental femur fractures in pediatric patients younger
than age 4 could be distinguished from child abuse using a
combination of presumed risk factors from the history,
physical examination findings, radiographic findings, and
age.
Methods We searched our institutions SCAN (Suspected
Child Abuse and Neglect) and trauma databases. We
identified 70 patients in whom the etiology of their femur
fracture was abuse and compared that group with 139
patients who had a femur fracture in whom accidental
trauma was the etiology.
Each author certifies that he or she has no commercial associations
(eg, consultancies, stock ownership, equity interest, patent/licensing
arrangements, etc) that might pose a conflict of interest in connection
with the submitted article.
Each author certifies that his or her institution approved the human
protocol for this investigation, that all investigations were conducted
in conformity with ethical principles of research, and that informed
consent for participation in the study was obtained.
K. Baldwin, N. K. Pandya, H. Wolfgruber,
D. S. Drummond, H. S. Hosalkar
Department of Orthopaedic Surgery, The Childrens Hospital
of Philadelphia, Philadelphia, PA, USA
H. S. Hosalkar (&)
Rady Childrens Hospital, UCSD, 3030 Childrens Way,
Suite 410, San Diego, CA 92123, USA
e-mail: HHOSALKAR@rchsd.org
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Introduction
Orthopaedic surgeons play a critical role in evaluating
potential cases of child abuse because fractures represent
the second most common presentation of abuse behind
only soft tissue injuries [23]. There are numerous studies
that have focused on the characteristics of fractures considered typical of abuse, including fractures of the femur
[1, 4, 5, 9, 14, 19, 28, 29], humerus [3, 12, 19, 31], tibia
[4, 12, 18], and ribs [6, 33]. Yet, orthopaedic surgeons are
less likely than general pediatric and emergency room
colleagues to identify abuse as the potential etiology of
these fractures, thus causing delay for appropriate multidisciplinary intervention [15, 26]. This is concerning
because of the million children annually in the United
States who are the victims of substantiated abuse, orthopaedic surgeons are often the first clinicians to evaluate
these patients, and if the cause of injury is not recognized,
these children will return to an abusive environment with a
50% risk for reinjury and a 10% risk of death [7, 13]. It is
therefore essential orthopaedic surgeons not only treat the
fractures these children present with, but also recognize the
associated etiologic characteristics of the injury that may
suggest child abuse.
When examining a fracture in the emergency room, the
following questions should arise: What patient characteristics may be indicative of abuse versus accidental trauma?
Is the history and mechanism of injury inconsistent with
the presenting injury? Does this fracture type, pattern, and
location represent potential abuse? Fractures of the femur
in young children provide an ideal model to develop a
systematic examination process to differentiate an abusive
from accidental etiology.
Fracture of the femur in children is the most common
musculoskeletal injury requiring hospitalization [5, 20].
Numerous studies describe fractures of the femur in young
children, and many of these have attempted to identify
fracture characteristics that may indicate abuse [2, 5, 8, 11,
20, 21, 24, 25, 28, 29]. The most common presentation
cited is the presence of a femur fracture in a patient
occurring either before walking age or before the second
birthday [5, 9, 13, 20, 28, 30]. In addition, several authors
have classified the radiographic appearance and location of
femur fractures as predictors of abuse [2, 15, 25, 28, 29] as
well as elements of the history (inconsistent history,
inappropriate delay, multiple presentations), physical
examination (examination inconsistent with history, head
injury or fracture in a child not of walking age), and
socioeconomic background [16, 22, 32]. A number of other
reports previously examined fracture patterns in children
younger than 48 months of age [6, 14, 16, 17, 26]. These
studies do not, however, allow a clinician to decide with
confidence whether a given femur fracture is likely caused
by abuse.
We therefore asked whether femur fractures caused by
abusive trauma could be distinguished from those caused
by accidental trauma using presumed risk factors in the
history, physical examination, and radiographic characteristics. We then built a predictive model based on those
factors.
799
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Baldwin et al.
Table 1. Demographic information for child abuse and accidental trauma patients for age, gender, and insurance status
Variable
All accidental
Number of patients
70
139
N/A
N/A
\ 0.001*
Age (months)
N/A
\ 0.001
0.033*
0.795
* Chi square test with Yates correction; Mann Whitney U test; Fishers exact test; **Interquartile range N/A = not applicable.
123
p value
801
Table 2. Comparison of current polytrauma, prior trauma, and history plausibility in child abuse and accidental trauma patients with femur
fractures
Variable
Number
of abuses
Percent abuse
(95% CI)
Number accidental
trauma
Percent accident
(95% CI)
Odds ratio
(95% CI)
p value
\ 0.001*
Current polytrauma
37/70
11/139
44/70
6/139
23/70
6/139
\ 0.001*
Raw number in parentheses; p values generated by Yates chi square test for independence; *statistically significant.
Table 3. Comparison of femur fracture location in child abuse and accidental trauma patients
Variable
Number
of abuses
Percent abuse
(95% CI)
Accidental
trauma
Percent accident
(95% CI)
Odds ratio
(95% CI)
p value
Proximal femur
14/70
19/139
0.33
Femoral diaphyseal
32/70
92/139
0.007*
Distal femur
26/70
28/139
0.01*
Raw number in parentheses; p values generated by Yates; chi square test for independence; odds ratios compare patients who are positive for
each fracture type as the outcome and abuse as the risk factor; *statistically significant.
victims of abuse had a greater frequency of current polytrauma (53% versus 8%), physical and/or radiographic
evidence of prior trauma (62% versus 4%), and histories
that were deemed suspicious for abuse (33% versus 4%)
(Table 2). Patients with accidental trauma more often had
diaphyseal femur fractures (46% versus 66%), abuse victims more often had distal femur fractures (37% versus
20%), and there was no difference in proximal femur
fractures between groups (Table 3). The odds of a femur
fracture being the result of abuse rather than accidental
trauma was greater for children younger than 18 months
(19.4 times) and patients of female gender (2.0 times)
(Table 1). Furthermore, abuse was associated more frequently with current polytrauma (13.0 times), physical and/
or radiographic evidence of prior trauma (37.5 times), and
patients with a suspicious history (10.8 times) (Table 2).
Finally, we used a multiple logistic regression model to
calculate a prediction rule for the chance of abuse given the
aforementioned risk factors. All of the variables that were
significant in any portion of the study were used. In addition, variables previously judged important were included
in the initial multiple logistic regression model. The variables were entered using the backward likelihood ratio
method for selection of variables. All variables were
entered and criteria of 0.10 by the 2 log likelihood
method was used for removal of variables. In the backward
regression analysis, only age younger than 18 months,
physical and/or radiographic evidence of prior injury, and
history of plausibility were predictive of an abusive etiology for child abuse. In this model, patients with a femur
Beta
statistic
Odds ratio
(95% confidence interval)
p value
2.0
7.2 (2.223.5)
\ 0.001*
5.0
155.5 (41.6581.0)
\ 0.001*
5.6
273.0 (28.12649.0)
\ 0.001*
* Statistically significant.
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Baldwin et al.
0 RISK
FACTORS
4.2%
1 RISK
FACTOR
2 RISK
FACTORS
24.1 %
87.2%
RISK OF ABUSIVE
FEMUR FRACTURE
3 RISK
FACTORS
92.3%
Results
A simple model using number of risk factors (age younger
than 18 months, physical or radiographic evidence of prior
injury, and suspicious history) predicted abuse in this age
group. Odds ratios were calculated based on the logistic
regression model versus a patient with no risk factors
(Table 4).
The logistic regression equation was then solved for each
number of risk factors to develop a prediction tool. In our
population, patients with no risk factors had a 4% chance of
having abuse as the etiology for their femur fracture, patients
with one risk factor had a 24% chance abuse was the etiology
of their femur fracture, patients with two risk factors had an
87% chance abuse was the etiology of their femur fracture,
and patients with three risk factors had a 92% chance abuse
was the etiology of their femur fracture (Fig. 1).
Discussion
Pediatric femur fractures are the most common musculoskeletal injury requiring hospitalization [5, 20], and their
presence in children raises suspicion for abuse [2, 5, 8, 11,
20, 21, 24, 28, 29]. In fact, it has been proposed that onethird of femur fractures in children younger than age
4 years and 80% of femur fractures in children who are not
yet walking have an abusive etiology [9]. Multiple studies
have attempted to classify the demographic and fracture
characteristics of children whose fracture may have an
abusive etiology, including age (particularly before walking age or the second birthday) [5, 9, 13, 20, 28, 30],
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803
Table 5. Risk factors found to be important or used to help diagnose child abuse
First
author
Historical features
Anatomic location
Coffey
67% (extremity
et al. [4]
injuries were in
patients younger
than 18 months)
N/A
N/A
N/A
Rex and
92% (younger than
Kay [28]
1 year)
N/A
N/A
N/A
Schwend
et al.
[30]
42% of children
younger than
walking age with
femur fractures
Multiple fractures
Leventhal
et al.
[17]
Suspicious history,
None listed for
change in behavior
femurs
or Medicaid payor
Multiple fractures
N/A
N/A
N/A
Bilateral injuries
Associated injuries
worked up more
often, but only 1/7
were positive
No particular distribution
Fong et al.
[6]
52% of abuse
patients younger
than 3 years old
(all fractures)
Worlock
et al.
[33]
80% abusive
fractures in those
younger than
18 months
No historical
Bruising of the head Rib fractures in the 50% metaphyseal chip in the femur
information available
and neck
absence of chest
in abuse patients; in other long
trauma, multiple
bones, spiral or oblique fractures
fractures
more common
Baldwin
et al.
[current
study]
* Based on the 2000 kids inpatient database; N/A = no available data in the study.
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Baldwin et al.
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