Which pair correctly lists per capita GDP from lower to higher?
Northern Africa, Western Asia
Written Questions
Articulate the similarity between events (natural and human) during the Younger Dryas and events projected during the next 50-100 years.
Dryas climate change stress -> invention of agriculture, new way of life . 21st century climate change stress likely also to force enormous changes.
"We can perhaps take as a moral guide the mythos of the world's remaining hunter-gatherers: we can learn to want less."
Wells: Paleolithic mythos of human expansion, control of nature unsustainable; must yield to wanting less to assure future human survival.
Obesity rates and home cooking vary inversely across national populations .
Home cooking less fat, sugar, processing than packaged food or take out, therefore less likely to cause obesity.
National populations vary dramatically in their age composition. Explain how age composition shapes national consumption priorities.
Diff generations -> different needs/priorities. "Older" populations high priority for pensions [or healthcare], "middle" for home ownership,
"younger" for education [or jobs].
Chapter 3: Diseased
Dollywood boasts extremely high levels of obesity - clinically obese - with body mass index (BMI) of 30 or greater.
Tennessee, Kentucky, Virginia, West Virginia, Alabama, Mississippi, among the fattest states in the country.
Mississippi, 1/3 of people are clinically obese - fattest state in the country.
Mississippi, Arkansas, and West Virginia are the poorest states in the country.
Poorest states also have 20 percent of population not completing high school.
85% of Americans now consider obesity an epidemic.
Obesity now the second most important root cause of illness and mortality (after cigarette smoking).
Richer countries tend to have lower obesity rates in the US.
In Europe, countries with lower average levels of education and per capita gross domestic product to have higher levels of obesity.
Key to producing an obesity epidemic is for a society to have just enough money and education to give it access to an excess of processed food and an inactive
lifestyle.
Diet of agriculturalists is fundamentally different from that of a hunter-gatherer. In general, Agriculturalists have a much higher percentage of carbohydrates in
their diet.
Chapter 4: Demented
Schizophrenics, psychotics, and manic-depressives showed they were very good artists.
Genome Scan - an analysis of hundreds of variable locations in the genomes of KE family members with and without the speech disorder.
By the time of the Neanderthals, around 500,000 years ago, spoken language had appeared.
FOXP2 gene thought to be responsible for development of speech!
Neanderthals would have been at a disadvantage in an environment like the one during the ice age 35,000 years ago, due to their hunting methods.
Climate change and social sophistication gave modern humans an advantage over Neanderthals.
40,000 years later Homo Sapiens had expanded to nearly every habitable location on the globe, settling Asia, Europe, Australia, and the Americas in only around 15
hundred human generations.
Complex speech allowed early humans to communicate new ways of solving the problems that came their way.
Our migrations were probably set in motion by necessity.
Volcanoes and Macromutations
Lake Toba (Northern Sumatra) is water -filled caldera of a dormant volcano (Mount Toba).
Toba was one of the largest volcanoes ever, it erupted sometime between 75,000 and 70,000 years ago.
Eruption resulted in "volcanic winter", cooling effect lasting several years.
Effects would have been devastating to early human populations.
World population at this time fell to fewer than 10000, maybe even fewer than 2000.
Human response was a change in culture.
First evidence of art shown in hand-carved ochre around 75000 years ago.
Great Leap Forward - abrupt change in behavior that heralds the Upper Paleolithic period, or Late Stone Age.
Seemingly trivial changes in an organism's DNA can have an enormous effect on its physiology or behavior.
Richard Lenski, through a computer program, showed that microevolution could explain traits like eyes after all, and thus in the end Darwin was right.
Process of trial and error coupled with better communication became the model for human innovation.
The Drone of Modern Life
Chapter 5: Fast-Forward
Charlie Whitaker diagnosed with Diamond-Blackfan anemia (DBA), leading family to seek designer baby for perfect bone marrow donor.
July 1978, Louise Joy, first child ever conceived by in vitro fertilization (IVF) - the original test tube baby.
Preimplantation Genetic Diagnosis (PGD) allows IVF team to predict the characteristics of future child.
Mohamed Taranissi - Whitakers' Physician.
June 16, 2003, Whitaker's baby is born c-section (Jamie)
Summer 2004 procedures begin, July 30 Charlie returns home after procedure.
Charlie declared officially cured in March 2007
Successful IVF pregnancy: 40% in women under 35, 10% in women >40
Average age of first pregnancy: 21.4 in 1971, 25.2 in 2003
Between 1960 and 2003, percentage of first births for women over 30 tripled from 7 to 22 percent.
10% of women >35 and 22% of women >40 use IVF to conceive.
The PGD procedure is increasing at a rate of 15 to 30 percent per year
PGD tests aneuploidy; abnormal chromosome count
Pleitropy: the many effects of a gene on the organism's phenotype.
Sickle-cell carriers: people with one mutated copy of the Malaria gene.
Trisonomy 21 - presence of 3 copies of chromosome 21 (Down's Syndrome)
People genetically similar can have different disease rates, depending on their lifestyle.
Genes alone dont tell the whole story; ultimately your DNA influences your health, doesnt determine it.
More than 90% of couples choose to terminate pregnancy and try again if fetus has down syndrome.
Healthcare costs increasing at 11% per year.
2008 - Genetic Information Nondiscrimination Act (protect rights of people with genetic disorders)
52% said they would use PGD for disease, 10 and 13 for height and intelligence.
Disinhibition - the lack of a behavioral "edit" mechanism, by which people limit their activity
One or two copies of genetic variants that predispose you to schizophrenia may also predispose you to being a great mathematician or composer.
W. French Anderson - first to treat genetic disorder with gene therapy.
The Wisdom of Repugnance - subconscious sense of right and wrong in biological modification.