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stiffness, and joint pain. Many types of over the counter anti inflammatory medicines
are available including ibuprofen and aspirin. Powerful medicines that have anti
inflamatory properties are the anti inflammatory steroids such as cortisol.
Antiinflammatory Drugs and Erectile Dysfunction
Surprisingly, Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen
also cause erectile dysfunction. Regardless of the reason for taking them, painkillers
classified as non-steroidal anti-inflammatory drugs (NSAIDs) apparently increase the
likelihood that middle-aged and elderly men will develop erection difficulties. A study
involved 1126 men, between 50 and 70 years of age, without erectile dysfunction in
1994 when they completed a questionnaire that included, among other things,
questions about erectile function and medication usage. The questionnaire was then
re-administered five years later. The investigators found that the erectile dysfunction
rate was 93 cases per 1000 persons per year among Nonsteroidal anti-inflammatory
drugs users compared with just 35 cases among nonusers.
Anti inflammatory drug - anti inflammatory meds for Tendon Injuries
Anti-inflammatory painkillers like ibuprofen and naproxen may not be effective in
many cases of tendon injury. Pain relievers known collectively as nonsteroidal antiinflammatory drugs, or NSAIDs, are often used to treat sore muscles and joints
because the body's inflammatory reaction to injury contributes to pain. However,
there is no reason to believe that NSAIDs heal tendon injuries known as
tendinopathy. Tendinopathy is a general term for disorders of the tendons, bands of
fibrous tissue that connect muscle to bone. The Achilles tendon, tendons in the
shoulder and the patellar tendon in the kneecap are commonly affected areas. While
the initial injury that leads to these tendon problems may involve inflammation in the
first several days, there is no evidence of ongoing inflammation in chronic
tendinopathy. Nor is there evidence that NSAIDs are an effective therapy after the
acute injury is over. In the absence of an overt inflammatory process, there is no
reason to use of NSAIDs in chronic tendinopathy. NSAIDs may bring some pain relief
from tendinopathy, they may, in the long run, hinder the healing process. Lab
research suggests, that while NSAIDs decrease certain inflammatory chemicals, they
may increase the production of substances called leukotrienes that could actually
further damage the tendon. Doctors also often use injections of cortisone, an antiinflammatory drug. But cortisone has the same issues as NSAIDs, and there is
evidence that the injections can make tendons more vulnerable to rupture. Source:
Clinical Journal of Sports Medicine, January/February 2006.
Antiinflammatory Drugs after surgery
Experiments in rats show that the antiinflammatory painkillers celecoxib (brand
name, Celebrex) and indomethacin, given after repair of a rotator cuff injury, impair
the healing process. Both painkillers belong to the class known as non-steroidal
anti-inflammatory drugs or NSAIDs, and recent lab studies have shown that NSAIDs
interfere with ligament healing. Researchers investigated the effect of NSAIDs on
bone-to-tendon healing. Rotator cuff repairs were done in 180 rats. Sixty animals
were then given the non-selective antiinflammatory NSAID indomethacin for 14 days,
60 were given the selective antiinflammatory NSAID celecoxib (a so-called COX-2
inhibitor) for 14 days, and 60 were given neither antiinflammatory drug. Five tendons
failed to heal -- four in the indomethacin group and one in the celecoxib group.
Significantly fewer tendons in the two NSAID groups than in the control group were
able bear weight normally. Even though NSAID treatment was given for only 14 days
after surgery, apparently this was enough time to interfere with healing. American
Journal of Sports Medicine, March 2006.
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