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MAGNESIUM THREONATE POWERS THE BRAIN.

(Dr Perlmutter)

Lately, in the lectures that I have been presenting to medical professionals, I


have been emphasizing the virtues of magnesium threonate. Aside from the
information Ive been presenting, I thought it would be good to actually visit
and review some of the exciting new information about what clearly appears to
be offering up an exciting new area of chemistry related to neuronal function
and brain function in general.

Learning is the process by which the brain is able to store new information by
forming new connections between neurons in what are called networks. This
process is an example of neuroplasticity. This process depends on the actual
formation of these connections, as well as the number of connections that are
available. We do know that when synapses, the connections that allow one
nerve cell to communicate with the next, are diminished, memory impairment
ensues. And indeed it is thought that this loss of synapses is an explanation for
what is called age dependent memory decline.
well studied including insulin, ghrelin, various trophic hormones, and, as we
have now learned, the ion magnesium, which enhances the activity of more
than 300 enzymes.

It has now been discovered that magnesium is a critical player in the activation
of nerve channels that are involved in synaptic plasticity. That means that
magnesium is critical for the physiological events that are fundamental to the
processes of learning and memory.

As it turns out, one form of magnesium, magnesium threonate, has the unique
ability to permeate the brain and enhance the receptors that are involved in
this process.

As reported in the journal Neuron researchers demonstrated actual


enhancement in the learning abilities, working memory, as well as short as well
as long-term memory and even quality of sleep, in laboratory animals, who
were given magnesium magnesium threonate.

One of the most aggressively studied forms of magnesium threonate is a


patented product called Magtein, developed by researchers at MIT including a
Nobel Prize winner. Their research has demonstrated actual restoration of
function in aging neurons in laboratory animals. Further, it appears that this
specific form of magnesium, Magtein, may in fact be the only form of
magnesium that significantly increases the levels of magnesium within the
brain.
Synapse formation is dependant upon a variety of factors that have been

MAGNESIUM THREONATE: DR: MERCOLA.

Most people do not welcome any thoughts of getting older because for many,
this is synonymous with occasional forgetfulness, loneliness, and general
decline in cognitive and physical capabilities.

It certainly is inevitable that your mental sharpness and physicality will decline
over time. But I can tell you from personal experience that this does not have
to be a depressing and unfulfilling time of your life.

Despite recently turning 60, I am the fittest I have ever been. I strive to live out
every day to its fullest potential. I may have been able to run faster when I was
younger, but I would never trade that for the muscle strength, flexibility, and
knowledge that I have today. While my experiences may not be representative
of your experiences, my point is that it is never too late to start implementing
healthy lifestyle strategies to enhance your life.

Fortunately, there are steps you can take to help enhance your wellness on
both physical and mental fronts. The bottom line... you don't have to just
reluctantly accept so-called senior moments as inevitable with nothing you
can do to make your life more enjoyable and full of vitality.*

Why Eating Your Veggies is so Important

When it comes to the food you eat, increasing your intake of fresh vegetables is
a surefire way to help support your overall health as times go by. Research has
shown that vegetables, such as spinach, could be beneficial in promoting
central nervous system and cognitive health.

Vegetable Diet Benefits


Adding more vegetables to your diet could play a key role in promoting
cognitive health.
So what turns vegetables into such powerful health-supporting allies?
Vegetables...

Pack a powerful array of free radical-fighting antioxidants


Contain phytochemicals which support healthy cell reproduction
Provide potent sources of vitamins and minerals
And when you eat your fresh veggies raw, you'll also receive what are called
biophotons. These are the smallest physical units of light used by all biological
organisms, including your body. The more sunlight a food can store, the more
nutritious it can be. Raw, fresh organic vegetables are rich in light energy.

In addition to eating raw vegetables, there's an even better way I believe you
can take advantage of their nutrient value...

Magnesium Pay Attention to this Vital Mineral

Another challenge you face as time marches on is your body becomes less
efficient and effective in absorbing important vitamins and minerals. So,
despite a healthy diet rich in fresh organic vegetables, you may still come up
short in certain nutrients.

Plus, consuming a larger number of vegetable servings a day can be somewhat


difficult... and may not always be entirely practical. Certainly, vegetable juicing
is a phenomenal way to overcome the serving challenge. But even then, there
may be some important nutrients you simply may not get enough of.

One nutrient that comes to mind one you probably dont hear much about is
magnesium.

Here are some key facts about this vital mineral and why I feel it's so important
for you not to overlook. Magnesium...

Is the fourth most abundant mineral in your body...


Exists in over 300 different bodily enzymes...
Is found primarily in your bones (50% of total body magnesium)...
Plays a role in your bodys detoxification processes...*
Aids your energy metabolism and protein synthesis...*
Helps guide a large number of physiological functions...*
Is required by glutathione (the 'master antioxidant') for synthesis...*
This should give you a pretty good picture why I believe magnesium is so
important. And the number of Americans potentially notgetting enough of this
mineral is estimated as high as 80%. Thats a pretty staggering number.

With all this said, how do you really know if youre getting an adequate supply
or coming up short? In fact

Is It Even Possible to Determine Your Magnesium Level?

Magnesium Level Test


Since only about 1% of the magnesium in your body is distributed in your
blood, there's really not an accurate lab test for magnesium today.
Due to the difficulty with determining magnesium status in your tissues, there's
really not a good lab test today that will provide an accurate assessment.

Additionally, only about 1% of the magnesium in your body is distributed in


your blood.

Some early signs of a potential lack of magnesium in your body include...

Loss of appetite and headache


Nausea and vomiting
Fatigue and weakness
As you can see, many of these symptoms are pretty general and can result
from a variety of different conditions. If you suspect youre low in magnesium,
your first course of action is to consult with a healthcare professional. But are
there any steps you can take yourself to help your body get a sufficient supply?

A Variety of Foods Rich in Magnesium

There are a number of foods with abundant supplies of magnesium. Raw, green
organic vegetables, such as spinach, are excellent choices because the center
of the chlorophyll molecule (which provides green veggies their brilliant color)
contains magnesium.

Chlorophyll is like a plant's version of our hemoglobin. They share a similar


structure but chlorophyll has magnesium plugged in the middle instead of iron.
In order to ensure you're getting adequate amounts of magnesium, I
recommend you first focus on eating a variety of foods that contain the
mineral. And juicing green leafy vegetables can be an excellent strategy for
obtaining magnesium as well.

Here's a handy chart of specific foods that contain abundant amounts of


magnesium for every 100 grams (just over 3 ounces) you consume...

Food (100 grams)

Magnesium Content (mg)

Seaweed, agar, dried

770 mg

Coriander leaf (spice), dried


Pumpkin seeds, dried

694 mg

535 mg

Cocoa, dry powder, unsweetened

499 mg

Basil, dried 422 mg


Flaxseed

392 mg

Cumin seed (spice)366 mg


Brazil nuts, dried

376 mg

Parsley, freeze dried


Almond butter

372 mg

303 mg

Cashew nuts, roasted

273 mg

Whey, sweet, dried176 mg


Leeks, freeze dried 156 mg
Kale, scotch, raw

88 mg

Why You Still May Not Be Getting Enough

Most people can maintain healthy levels of magnesium by simply consuming


plenty of foods rich in the mineral (like those foods in the chart above).
However, there are certain factors (some of which I've already touched on)
which can potentially impact levels of magnesium you consume and your body
absorbs:

Time Simply over time, your body inherently faces challenges that can lead to
decreases in nutrient absorption including magnesium.
Types of food you eat If you consume mostly non-organic foods, their
magnesium levels may be depleted due to chemical fertilizers and pesticides.
The levels of magnesium in food are dependent on the levels found in the soil.
Medication Certain medicines can contribute to the magnesium deficit within
your body.
Practicality It simply may not be possible for you to consume enough foods
rich in magnesium. Some people may not have access to organic supplies of
these foods. However, I strongly recommend that you put the extra effort in to
try and find, and make some of these foods part of your regular diet.
Sometimes, it just takes hard work to maintain a healthy diet.

If any of these factors come into play in your life and you're concerned about
maintaining adequate levels of magnesium, you might want to consider a highquality supplement.

But high-quality is the absolute key when deciding on a magnesium


supplement. There's such a wide-variety of options available to you, it can not
only be confusing, but certain supplement combinations can affect the
absorption and bioavailability of the magnesium nutrient.

And that's why I decided to take the guesswork out of finding a high-quality
magnesium formula and put my team to task to find the best solution for you.

My Must-Haves for a High-Quality Magnesium Supplement

My preferred approach when recommending any supplement is to first compile


a list of the essential requirements. With magnesium, here's the list my team
and I put together that I feel is an excellent guideline to help you "weed-out"
those supplements that fail to make the grade.

For a high-quality magnesium supplement, make sure it:

Completely avoids magnesium stearate Magnesium stearate is not a source


of magnesium. It is in fact a flow agent used in production that prevents
supplements from sticking together. It can potentially inhibit absorption of
nutrients inyour digestive tract.
Delivers a high-absorption formula Its not just about the amount of elemental
magnesium found in the supplement. The formula must have high-absorption
capabilities.
Incorporates high-penetration characteristics Absorption of magnesium is
crucial but its also important that the nutrient is capable of penetrating key
tissues and cells to be effective.
Takes advantage of a high-technology encapsulation and delivery system The
total formula package must include a high-quality encapsulation and delivery
system to help ensure consistent protection and delivery of the mineral. In my
opinion, some manufacturers really fall short in this area by employing cheap
solutions.

Helps manage potential discomfort Many magnesium products are used as


laxatives and antacids. Since these are not the driving-force behind this
magnesium supplement, I recommend avoiding any that are specific to stoolsoftening and so-called indigestion aids.
Provides practical, easy-to-take servings Supplement servings must be
practical to fit into anyones busy schedule. Serving size should be straightforward with well-defined guidelines.
With some confusion out there about the use of magnesium stearate in
supplements, I feel even more straight-talk is needed as to why you should...

Steer Clear of this Pretender

Many supplement manufacturers add magnesium stearate to their formulas.


However, it's not only something I don't recommend; in my opinion, it's
something to seriously watch out for and avoid in any supplement you take.

But why is that? Isnt magnesium stearate a form of the mineral itself? Heres
why I strongly recommend you scrutinize any supplement and dont go near it
if contains this compound because magnesium stearate...

Is not a source of magnesium to help boost your bodily supply


Is a chalk-like lubricating compound used to prevent supplements from sticking
together during the manufacturing process
May be sourced from genetically engineered (GE) hydrogenated oils
The bottom line with magnesium stearate I believe you should avoid it
completely. If you're taking a supplement, make sure it's a high-quality foodbased supplement that does not contain potentially harmful fillers and
additives like magnesium stearate. And that certainly applies when selecting a
high-quality magnesium supplement.

Magnesium Supplements A Minefield of ChoicesOne daunting challenge you


face when searching for a high-quality magnesium supplement is that there's
such a wide variety available... so much so, that it can be quite confusing as to
which one is really best to help enhance your levels.

Plus, to add a bit more confusion, there's no such thing as a 100% magnesium
supplement. Magnesium must be bound to another ion and that substance can
affect magnesium's absorption and bioavailability.

So let me help you get through this magnesium minefield and show you why I
believe my selection is a wise choice for you if you're looking for a magnesium
supplement.

But first, let's take a closer look at the different types of magnesium
supplements available out there and some characteristics of each one. Here's a
helpful chart to give you some basic background information info everyone
should be up-to-date on when considering magnesium supplementation.

Magnesium supplement

Characteristics

Magnesium glycinate
A chelated form of magnesium that tends to provide
effective levels of absorption and bioavailability.
Magnesium oxide A non-chelated form of magnesium bound to an organic acid
or fatty acid. Contains up to 60% elemental magnesium and has stool-softening
properties.
Magnesium chloride/Magnesium lactate
Contains only about 12%
elemental magnesium but tends to have better absorption capabilities than
magnesium oxide which has 5 times the magnesium.
Magnesium sulfate/Magnesium hydroxide
These are typically used as
laxatives. Milk of Magnesia is an example of this type of magnesium. Since
magnesium hydroxide can have up to 42% elemental magnesium, caution is
required here not to take too much.
Magnesium carbonate
This form of magnesium has antacid properties and
can contain from 29-45% elemental magnesium.
Magnesium taurate
This contains a combination of magnesium and
taurine (an amino acid) that together may provide a calming effect on the body
and mind.
Magnesium citrate This is a form of magnesium with citric acid which has
laxative properties. This can contain up to 16% elemental magnesium.

Magnesium threonate
This newer, emerging type of magnesium supplement
has shown great promise in absorption, as well as potential tissue and cell
membrane penetration.
Confusion between Elemental and Absorption Rate

"Elemental" magnesium refers to the actual amount of magnesium in each


supplement form. However, this is by no means the whole story.

Just because the supplement contains more elemental magnesium doesn't


necessarily mean it's formulated for high-absorption. Plus, there are some
types of magnesium supplements you may absorb well but they have stoolsoftening properties you probably want to avoid.

So, what to do?

Magnesium Threonate How This Formula Exceeded My Expectations

If you're looking for a magnesium-based laxative or antacid solution, that is a


whole different ball game, and a subject for another time. But if you're in
search of a magnesium supplement to help support your levels due to any of
the potentially influential factors I described earlier... time... foods you eat (or
don't eat)... medicines... diet practicality,* I feel I can help save you a ton of
time.

For a high-quality magnesium supplement, I strongly recommend Magnesium


Threonate. Heres a chart showing the detailsbehind why I think this is such a
fantastic formula and how it exceeded my expectations by surpassing the
checklist requirements:

Checklist requirement

Magnesium Threonate?

Completely avoids magnesium stearate?


Yes I made certain this compound was not part of the formula whatsoever. It's
just not a healthy substance you should be putting in your body. Plus, this
formula does not contain any genetically engineered (GE) ingredients as well.
Delivers a high-absorption formula?

Yes With the many types of magnesium supplements available, my team and
I selected magnesium threonate (Magtein) for its breakthrough absorption
characteristics and extensive research. As this magnesium solution is
formulated in a water/glycerin matrix (as opposed to powder-based formulas
prevalent on the market), the magtein is presolubilized to enhance absorption
capabilities.
Incorporates high-penetration characteristics?
Yes One area where other forms of magnesium supplements tend to fall short
involves penetration of tissues and cells. Animal studies have shown how
magnesium threonate has been able to uniquely cross the blood-brain barrier
and penetrate cell membranes.*
Takes advantage of high-tech encapsulation and delivery system?
Yes The Licaps encapsulation/delivery package is fully compatible with the
water/glycerin system to form a formidable absorption combination.
Helps manage potential discomfort?
Yes Many forms of magnesium can cause unpleasant gastrointestinal
discomfort. In fact as you already know, some magnesium products have the
primary purpose of softening stool and acting as a laxative. This is certainly not
the case with Magnesium Threonate and its consistent formula.
Provides practical, easy-to-take servings?
Yes By taking 1 g after lunch time (or in the afternoon) and 1 g at bedtime
with plenty of water, it's easy to take. Food is not required for absorption so
taking it with meals is not necessary. It's always a smart choice to double-check
and consult with a healthcare professional when taking any supplement. I
believe by now you can see why I'm so excited about the Magnesium
Threonate formula. If you're truly looking for a high-quality magnesium
supplement to add to your healthy diet, it has my highest recommendation.

And here's more on how this extraordinary formula uses...

High-Technology Encapsulation That's Off-the-Charts

In addition to the extraordinary mineral ingredient (Magtein) behind the


Magnesium Threonate supplement, it also capitalizes on a capsule delivery
system I consider top-of-the-line.

Its this combination of the Magtein nutrient and high-tech


encapsulation/delivery system (Licaps) which makes the supplement an
outstanding magnesium-supporting solution for you.

Magnesium Level Test


With the Licaps high-technology encapsulation system, leakage potential is all
but reduced to zero.
Here are a few more details on why the delivery system works so well. Licaps is
truly a unique capsule in how its extraordinary technology protects the
enclosed nutrients from potential:

Leakage Uses an innovative hermetic sealing process


Oxidation Helps ensure nutrient freshness by employing a nitrogen-flushing
process during filling of the capsule
Tampering By creating an airtight capsule, its almost impossible to open a
Licaps capsule without leaving visible damage
With this high-quality delivery and encapsulation system, combined with the
high-quality mineral ingredients of Magtein, I truly believe that Magnesium
Threonate is one supplement you should consider adding to your overall
healthy diet.

Don't Let Poor Lifestyle Choices Put the Brakes on Fully Enjoying Your Life

Now that Ive reached age 60, I'm living proof of how you can live your life to
its full potential if you make intelligent lifestyle adjustments as you go.
And this could be one of those times to make another well-informed
adjustment. Even though you may eat a diet rich in magnesium, it's still
possible to come up short. That's where Magnesium Threoneate can help.

With Magnesium Threonate, you can have a high-quality magnesium


supplement with superb absorption one with a type of magnesium (Magtein)
that animal research suggests can cross the blood-brain barrier and penetrate
cell membranes.

Its one of the most practical ways I know of to help balance your overall intake
of this vital mineral. And its so easy to take regardless of how busy your

schedule gets. Its a simple add to support your overall healthy lifestyle
strategy.*

Order Magnesium Threonate today to start taking advantage of everything that


this phenomenal mineral has to offer.*

Label Snapshot for Magnesium L-Threonate


Supplement Facts
Serving Size: 4 Licaps capsules
Servings Per Container: 30
% Daily ValueAmt. Per Serving
Magnesium (from Magtein Magnesium-L-Threonate)
144 mg

36%

Magtein (Magnesium-L-Threonate)
2000 mg

**%

*(%)Percent Daily Values are based on a 2,000 calorie diet.


**Daily Value not established.
Other Ingredients: Glycerin, Vegetable Cellulose, Purified Water
Suggested Use: As dietary supplement, take four(4) Licaps capsule daily.
Two(2) mid-day and two(2) at night, 2 hours before bed.
View Complete Product Label

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