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WESLEYAN UNIVERSITY -PHILIPPINES

Mabini Extension, Cabanatuan City


Philippines 3100
COLLEGE OF NURSING AND ALLIED MEDICAL SCIENCES
BACHELOR OF SCIENCE IN PHYSICAL THERAPY
2ND Semester, AY 2014 -2015
I.

Course Code: NeuroSci

II.

Course Title: Neuroanatomy and neurophysiology

III.

Course Description:

The course focuses on the structure of the human brain and spinal cord, including the
functional organization of the central nervous system. This course will entail extensive,
hands-on examination of human brain models as the primary means for instruction and
learning. This experience will be supplemented by use of interactive digital atlases to
learn the gross anatomy of the central nervous system and the organization of the major
neural systems underlying sensory, motor and cognitive function.
IV. Credit Units: 3 Units Lecture & 1 Unit Laboratory
V. Contact Hours: 3 Lecture Hours /Week & 2 Laboratory Hours/Week
VII. Pre-requisites: Physiology
TIMETA
BLE

WEEK 1

WEEK 2

SESSION TOPICS
OBJECTIVES
Introduction/presentation/orientation of the course (that includes
the syllabus,grading system, textbooks and references).
Introduction
and
Organization
of the
Nervous
System
Neurobiology
of the Neuron
and the
Neuroglia

1. To understand the basic organization of the main


structures that form the nervous system
2. To gain a three-dimensional appreciation of the parts
of the brain and their relative positions to one another.
1. To define the neuron and name its processes
2. To learn the varieties of neurons and identify them in
the different parts of the nervous system
3. To review the cell biology of a neuron and understand
the function of a nerve cell and its processes
4. To review the structure of the plasma membrane as it
is related to its physiology
5. To learn the transport of materials from the cell body
to the axon terminals
6. To understand the structure and function of synapses
and neurotransmitters

7. To review the supporting function of the neuroglial


cells for nerve cells and the possible role that they play
in neuronal metabolism, function, and neuronal death

1. To understand the embryological development of the


nervous system

WEEK 3

Embryological
Development
of the Nervous
System

2. To understand the major embryological subdivision of the


central nervous system as seen on the surface of the human
forebrain, hindbrain and spinal cord.
3. To visualize the relationship of different parts of the
nervous system
4. To understand how the different nerve tracts insinuate
themselves between the central masses of gray matter

WEEK 4

The Cerebrum

1. To introduce the student to the complexities of the


forebrain
2. To understand the definition of the diencephalon and
accurately localize the thalamus and hypothalamus by
studying the sagittal, coronal, and horizontal sections of
the brain
3. To understand the exact position of the main conduit
of the ascending and descending tracts, namely the
internal capsule, which is so often the site of pathologic
lesions

1. Describe the four lobes of the cerebral hemispheres


and the neuroanatomical landmarks that define their
boundaries in the human brain.
2. Identify major gyral and sulcal formations of the
human cerebral cortex.
3. To describe the basic structure and functional localization
of the highly complex cerebral cortex.

WEEK 4

The Structure
and
Functional
Localization
of the
Cerebral
Cortex

4. To discuss the major functions that are localized in a


clinically significant fashion to each of the four lobes of
the cerebral hemispheres of the human brain.
5. To describe the layers of the cerebral cortex as
distinguished by the type, density, and arrangement of their
cells .
6. To understand the precise division of the cerebral cortex
into different areas of specialization, as described by
Brodmann

1. To describe the thalamus and its functions.


The
Diencephalon:
Hypothalamus
and its
connections

WEEK 5

2. To idenfity the subdivisions of the thalamus


3. To discuss the nervous connections of the thalamus,
thalamic nuclei including its location and functions.

1. To identify the location and boundaries of the


hypothalamus and various hypothalmic nuclei
The
Diencephalon:
Thalamus and
its connections

2. To discuss the main nervous connections of the


hypothalamic nuclei including its functions.

3. To describe the connection between the hypothalamus and


pituitary gland and understand the functions of the
hypothalamohypophyseal tract and hypophyseal portal
system and its functions.

PRELIM EXAMINATION
WEEK 7
1. To provide a brief overview of the structure and function of
the reticular formation
The Reticular
Formation and
the Limbic
System

The Basal
Nuclei (Basal
Ganglia) and
Their
Connections

2. To identify the parts of the limbic system and its functions


3. To discusss the major nervous connections of the reticular
formation and limbic system.

1. To describe the basal nuclei, its subdivisions, their nuclei,


nervous connections, pathways and their functions and relate
them to diseases commonly affecting this area of the nervous
system

WEEK 8

The Brainstem

1. To review the anatomy of the skull, cranium and brainstem


2. To develop a three-dimensional picture of the brainstem
(Interior and exterior)
3. To understand the positions of several of the cranial nerve
nuclei, the olivary nuclear complex, and the paths taken by
the various ascending and descending nerve tracts as they
ascend to the higher brain centers or descend to the spinal
cord
4. To assess the signs and symptoms presented by a patient
and identify the exact location of a structural lesion

WEEK 9
The Cranial
Nerve Nuclei
and Their

1. To discuss the basic organization of the cranial nerves


including their motor and sensory nuclei, their locations and
central connections

Central
Connections
and
Distribution
2. To understand the functions and components of each of the
12 cranial nerves

WEEK 10
1, To discuss the main arteries and veins supplying the brain
and spinal cord
The Blood
Supply of the
Brain and
Spinal Cord

2. To identify the areas of the cerebral cortex and spinal cord


supplied by a particular artery and to understand the
dysfunction that would result if the artery were blocked
3. To understand the circle of Willis as well as the blood
supply to the internal capsule
4. To trace the major vessels that supply the anterior and
posterior arterial circulation to the forebrain, hindbrain and
spinal cord

MIDTERM EXAMINATION

1. To understand the structure and function of the three


meninges that surround the brain and spinal cord
The Meninges
of the Brain
and Spinal
Cord

2. To understand the venous sinuses within the skull and see


how the meninges contribute to their walls
3. To appreciate the relationship of the meninges to the
different forms of cerebral hemorrhage

WEEK 12

The Ventricular
System,
Cerebrospinal
Fluid, and the
Blood-Brain
Barrier

1. To identify the location, functions, origins, and the flow of


the cerebrospinal fluid
2. To understand the structure and function of the blood-brain
and bloodcerebrospinal fluid barriers
3. To learn how certain parts of the brain are protected from
trauma and potentially toxic drugs or other exogenous
materials

WEEK 13
The Spinal
Cord and the
Ascending and
Descending
Tracts

1. To understand the position of the main nervous pathways


and nerve cell groups in the spinal cord as well as be able to
correlate radiologic evidence of bone injury with segmental
levels of the spinal cord and neurologic deficits
2. To discuss the basic structure of the delicate spinal cord
and the positions and functions of the various ascending and
descending tracts that lie within it
3. To trace the pathways of each of the ascending and
descending tracts, showing their cells of origin, their course
through the central nervous system, and their destination

WEEK 14
The Ventricular
System,

1. To identify the location, functions, origins, and the flow of


the cerebrospinal fluid

Cerebrospinal
Fluid, and the
Blood-Brain
Barrier

2. To understand the structure and function of the blood-brain


and bloodcerebrospinal fluid barriers
3. To learn how certain parts of the brain are protected from
trauma and potentially toxic drugs or other exogenous
materials

WEEK 14
The Autonomic
Nervous
System

1. To discuss the basic organization of the Autonomic Nervous


system, including its 2 primary divisions; Sympathetic and
Parasympathetic Nervous System
2. To understand the structure, components and function of
the Sympathetic and Parasympathetic Nervous System
3. To understand the effects of the Sympathetic and
Parasympathetic Outflow on specific organs of the human
body

WEEK 15
The Peripheral
Nerves,
Receptor and
Effector
Endings

1. To understand the basic structure and function of nerve


fibers
2. To understand the process of nerve degeneration and
regeneration
3. To review the special organs that lie at the ends of sensory
and motor nerves
4. To compare the different types of encapsulated and nonencapsulated receptors and discuss their functions and
locations

FINAL EXAMINATION

TEACHING METHODS & STRATEGIES:


1. Case presentation
2. Presentation of Evidence-based research
3. Journal Reports related to the case presented
3. Individual assignments and reports
4. Reading assignments and independent study
EVALUATION:
Recitation
Quizzes
Research work
Periodical Examinations
Textbook & References:
Snell, Richard S. Clinical Neuroanatomy. 7th Edition. Lippincott Williams and Wilkins, China., 2010
Gilman, Sid and Newman, Sarah Winans. Manter and Gatzs Essentials of Clinical Neuroanatomy

and Neurophysiology. 10th Edition, FA Davis. 2003


Netter, Frank H. MD. Atlas of Neuroanatomy and Neurophysiology. Selections from the Netter

Collection of Medical Illustrations. Icon Custom Communications. 2002.


Fisch, Adam MD. Neuroanatomy. Draw it to know it. Oxford University Press. NY. 2009.

GRADING CRITERIA:
Class Standing (CS)
Breakdown:

100%

Quizzes
=
Case
Presentation
Recitation =
Assignments
Attendance =
Behavior
=

30%
=
40%
10%
=
5%
10 %
5%

Computation
Examination Grade
(100 X 60 + 40)

Class Standing (CS) Grade


Term Grade

(Raw Score/ Total exam items) X 100)

(CS raw Score / 100) X 60+40

Class Standing Grade X 2 + Examination Grade

Prelim Grade + Midterm Grade + Raw Final

3
(Prelim/Midterm/Finals)
Final Grade
Grade 3

PREPARED BY:
APPROVED BY:
Jacinto Jose P. Gapud, PTRP
Ed.D, RN
PT Coordinator

REVIEWED AND

Wilfredo C. Ramos,
Dean, CONAMS

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