A SURVEY ON THE SALE OF INSULIN THROUGH

RETAIL STORES NEAR THE HOSPITALS

DONE FOR ELI LILLY & COMPANY (INDIA)

SUBMITTED BY:
RAHUL SHUKLA

AMITY BUSINESS SCHOOL

 CONTENTS

1. ABOUT THE COMPANY

2. VISION OF THE COMPANY
3. DIABETES MELLITUS – DEFINITION
4. PILLARS OF MANAGEMENT OF DIABETES
5. INSULIN – types
6. ABOUT THE PRODUCTS – NOVOMIX, NOVORAPID,
LANTUS & HUMALOG
7. VISIT TO HOSPITALS AND RETAIL STORES
RML HOSPITAL
BALRAAMPUR HOSPITAL
KGMC
CIVIL HOSPITAL
 ABOUT THE ELI LILLY & COMPANY (GLOBAL)

• A heritage more than 130 years strong: company founded on

May 10, 1876
• Headquarters located in Indianapolis, Indiana, U.S.A.
• Approximately 40,788 employees worldwide
• Approximately 7,474 employees engaged in research and
development
• Clinical research conducted in more than 50 countries
• Research and development facilities located in 8 countries
• Manufacturing plants located in 13 countries
• Products marketed in 143 countries

Eli Lilly and Company has been in business more than 132 years.
The global, research-based company was founded in May 1876 by
Colonel Eli Lilly in Indianapolis, Ind., in the Midwestern section of
the United States. A 38-year-old pharmaceutical chemist and a
veteran of the U.S. Civil War, Colonel Lilly was frustrated by the
poorly prepared, often ineffective medicines of his day.
Consequently, he made these commitments to himself and to
society:
• He would found a company that manufactured
pharmaceutical products of the highest possible quality.
• His company would develop only medicines that would be
dispensed at the suggestion of physicians rather than by
eloquent sideshow hucksters.
• Lilly pharmaceuticals would be based on the best science of
the day.
Although his business flourished, Colonel Lilly wasn't satisfied with
the traditional methods of testing the quality of his products. In
1886, he hired a young chemist to function as a full-time scientist,
using and improving upon the newest techniques for quality
evaluation. Together, they laid the foundation for the Lilly
tradition: a dedication that first concentrated on the quality of
existing products and later expanded to include the discovery and
development of new and better pharmaceuticals.
Eventually, Colonel Lilly's son, Josiah K. Lilly Sr., and two
grandsons, Eli Lilly and Josiah K. Lilly Jr., each served as president
of the company. And each contributed a distinctive approach to
management. Together, these management styles established a
corporate culture in which Lilly employees were viewed as the
company's most valuable assets, a belief that is still the
cornerstone of our corporate philosophy.

ABOUT THE COMPANY – LILLY INDIA

Eli Lilly and Company (India) Pvt. Ltd is a subsidiary of the US

pharmaceutical major, Eli Lilly and Company.

The company was set up in 1993 primarily to manufacture and

market a select range of drugs. After its inception in 1993, the
Indian operation achieved a quick break-even in 1996. In August
2001, a 100% Lilly subsidiary was created, Eli Lilly and Company
(India) Pvt. Ltd.

In India, we strive to touch the lives of our customers not only with
our path-breaking medicines, but also by providing the medical
fraternity with a range of information, critical to their
understanding and treatment of diseases and people.

This is accomplished through a team of 500 dedicated individuals

based across the country that provides our products and services
to medical practitioners and hospitals.

Everyone has a mission. Ours is a very simple one. To provide

"Answers That Matter". Answers that we get by innovating,
answers that enable people to live longer, healthier and more
meaningful lives.

Lilly's innovative products have been an answer to the needs of

the people suffering from Diabetes, Cancer, Sepsis, Osteoporosis,
Cardio vascular disorders, Growth hormone deficiency and many
other diseases, creating not only awareness among patients and
their well wishers but also giving them assurance and confidence
about managing diseases at a lower cost.
Diabetes Mellitus – is a disease caused by the deficiency of
insulin in the body. The main clinical features of disease are
excessive thirst and hunger, frequency of urination and
susceptibility to infections.

There are two types of diabetes

Type –I: Juvenile Diabetes which means diabetes affecting

children. It is also known as Insulin Dependent Diabetes. Type 1
diabetes results from destruction of the Beta-cell of the pancreas,
usually leading to absolute insulin deficiency. Thus people with
type 1 diabetes cannot produce insulin to utilize glucose for
energy. They require insulin from outside to control their blood
sugar levels.

Type – II: Adult type or Maturity onset diabetes which affects

people over 25 years of age. It is also called Non- Insulin
Dependent Diabetes. People with type 2 diabetes either produce
insufficient quantities of insulin or the quality of the insulin
produced is poor leading to insulin resistance. They may or may
not require insulin from outside source. Type 2 diabetes accounts
for 90-95% of all people with diabetes worldwide.

In order to declare a person to be suffering from diabetes mellitus,

the fasting blood sugar level should be above 120 mg per cent
and the post prandial blood sugar should exceed 140 mg per cent.
Pillars of Management of diabetes

Management of Diabetes includes four modes of treatment which

are: Diet, Exercise, Medicine and education. The common
objectives form these modes are to improve blood glucose levels,
maintain ideal weight, provide adequate nutrition, avoid acute
complication and prevent vascular complications
INSULIN – An important Anti-diabetic drug

Important varieties of Insulin- The Insulin preparations are

generally grouped under three categories:

1. Fast & Short Acting

2. Immediate Acting
3. Long Acting

Soluble or neutral Insulin produces a very prompt action

within half an hour but duration is short i.e 6 to 8 hours. It is
needed during surgery.
Doses – 3 times a day.

Isophane Insulin – it is Protamine added suspension of

regular or neutral insulin. Its action starts slowly within one
to two hours but lasts for 18 to 24 hours
Doses – twice a day.

Protamine zinc Insulin or PZI is a suspension of regular

Insulin added with Protamine and Zinc. Its action starts
slowly ranging from 3 to 6 hours and lasts for up to 24 hours.
Doses – a single dose before breakfast.

Biophasic Isophane Insulin is a mixture of soluble neutral

Insulin and Isophane Insulin generally in a ratio of 30:70 .
This has advantage of both rapid and intermediate acting
insulin through a single preparation. It is ideal for Type – II
diabetes.
The two indispensible varieties of Insulin preparations are as
under

1. Chromatographically pure crystalline porcine

insulin
2. Human Insulin produced by recombinant DNA
technology. It is available in the mixture of neutral insulin
30 percent and Isophane Insulin 70 percent and today in
spite of being costlier it is a preferred therapy

Newer Human Insulin analogs produced by

recombinant DNA technology with minimal changes
in Amino Acid Sequences.
NOVORAPID - is a medicine which is used in diabetes mellitus.
NovoRapid contains insulin aspart. It is supplied by Novo Nordisk
Limited

NOVOMIX - it is used in diabetes mellitus. It is manufactured by

Novo Nordisk Ltd
NovoMix is a range of white suspensions for injection. It is
available in cartridges or in prefilled pens. NovoMix contains the
active substance insulin aspart 100 units (U) per millilitre:
NovoMix 30:
30% soluble insulin aspart (rapid acting) and 70%
protamine-crystallised insulin Aspart (long acting),
NovoMix 50:
50% soluble insulin aspart (rapid acting) and 50%
protamine-crystallised insulin aspart (long acting),
NovoMix 70:
70% soluble insulin aspart (rapid acting) and 30% protamine
crystallized insulin aspart (long acting).

LANTUS –
Lantus® (insulin glargine [rDNA origin] injection) is a new
true once a day background insulin from Aventis
Pharmaceuticals. It represents a remarkable breakthrough in
that it is the first insulin to offer truly flat insulin levels through
the entire day for most users. It can be used by people with
Type 1 or Type 2 diabetes who are six years old or older.

HUMOLOG - Humalog® (insulin lispro) is a prescription form of

insulin used to treat type 1 and type 2 diabetes. It is a rapid-
acting insulin, used to help control the spike in blood sugar that
occurs after meals. It is typically used in combination with a long-
acting insulin. The medication can also be used in an insulin
pump.

This article refers to plain Humalog. Humalog is also available in

combination with an intermediate-acting insulin (Humalog
Mix75/25® and Humalog Mix50/50®)
It is manufactured by Elli Lilly and company.

Hospital Name – RML (Ram Manohar Lohiya Hospital)

Insulin in Hospital’s Pharmacy –

Recosulin manufactured by Shreya Pharmaceuticals Ltd.
Cost of Insulin – Rs. 144

Leading doctors who prescribe Insulins –

Dr. Sandeep Choudhry (maximum priscriptions)
Dr. V. D Verma
Dr. S.K Srivastava
Dr. N. Dev
Dr. Ashok Srivastava
Dr. R.K Jain
Dr. A.C Dwivedi

Retail chemists Visited

SAI medical store
Kailash Medical store
Shiva Medical store
Vishal Medical Store

Insulin sold through Retail Chemists

Humicilin 30/70 manufactured by Lilly and company
Cost – Rs. 159

Human Actrapid 40 manufactured by Abott pharmaceuticals.

Name of the Hospital – Balraampur

Insulin in hospital’s pharmacy –

Human Insulin R manufactured by Biochem
Insogen Biochem 130
Cost – Rs. 142

Leading Doctors who prescribe Insulin

Dr. A.C Srivastava
Dr. R.R.P Singh

Retail Chemists Visited

Bharat Medical Store and others

Insulin sold through Retail Chemists

Humicilin 30/70 manufactured by Lilly & Company
Cost – Rs. 159
Name of the Hospital – KGMC

Insulin in Hospital’s Pharmacy –

Human Insulin by Biochem
Cost – Rs. 142

Leading doctors who prescribe Insulin

Dr. D Himanshu (Gandhi Ward)

Retail Chemists Visited

Vishal Medical Store
KGN Medical store
Krishna Medical store
Shukla Medical store
NR Pharma store

Insulin sold through Retail Chemists

Humicilin by Lilliy & Company
Cost – Rs. 159

Human Actrapid 40 by Abott

Name of the hospital – CIVIL hospital

Insulin in Hospital’s Pharmacy –

Recosulin manufactured by Shreya Pharmaceuticals Ltd.
Cost of Insulin – Rs. 144

Name of the Doctors prescribing Insulin

Dr. N.K Bansal
Dr. Pradeep Tiwari
Dr. A.K Sharma
Dr. R.K Gautam

Retail Chemists Visited

Dawaghar.com
Anurag Medical Store
Maha Medicals

Insulin sold through retail chemists

Human Mix Start manufactured by Abott.
Humicilin (only few) by Eli Lilly & company.