Eksipien Signet

AC-DI-SOL
Croscarmellose Sodium USP/NF, EP, JP

Ac-Di-Sol is a crosslinked sodium CMC that facilitates rapid disintegration and drug dissolution
in tablets, capsules and other solid dosage forms. It performs dual functionality of water wicking
and rapid swelling resulting in it's superior disintegration characteristics.
Grade
Description
Application
Ac-Di-Sol SD711
Cross linked Sodium

CMC or Modified
Cellulose Gum
Highly effective in wet granulation & direct

compression products, independent of tablet
hardness with low use level and excellent stability.
Best known super disintegrant that is effective intra
and extra-granularly.
ALVEOSUCRE
Agglomerated Sucrose USP/NF, EP, JP

Alveosucre is obtained by wet granulation of pure icing sugar followed by subsequently drying
in a fluidized air bed and then sieved.
Grade
Description
Highly absorbent,
Alveosucre fine allows for structured
mixtures with
homogenetic
distribution of active
ingredients while
Alveosucre
avoiding sedimentation
with dextrin
or separation of
ingredients. Instant
cold dissolution
Application
Fast dissolution instant sugar for homogenous dry
mixes and sachet filling.
Designed for dry mixes formulae and direct
compression. Has high compaction rate.
SHIN-ETSU AQOAT (HPMCAS)
Hypromellose Acetate Succinate USP/NF, JPE

AQOAT is an enteric coating material which was first approved in Japan in 1987. Subsequently
the product was approved in Korea, Europe and USA.
Hypromellose acetate succinate is manufactured from highly purified pulp and involves
introduction of acetyl and succinoyl groups into the hydroxyl backbone of Hypromellose.
Various grades of AQOAT are available which differ in the particle size and chemical
substitution levels.
The polymer, Hypromellose acetate succinate, lends itself to use in different coating techniques aqueous, solvent based, ammonia neutralization and dry / deposition coating. It can also be
recommended in solid dispersions to enhance the bioavailability of poorly soluble drugs as well
as in the design of controlled release dosage forms for targeting drug release to specific
gastrointestinal sites.
Description
Grade
Dissolving
pH*
5.5
Acetyl (%) /
Succinoyl
(%)
Mean
particle size
Application
8 / 15
Aqoat AS-LF
Aqoat AS-MF
6.0
9 / 11
Aqoat AS-HF
6.5
12 / 7
Aqoat AS-LG
5.5
8 / 15
Aqoat AS-MG
6.0
9 / 11
Aqoat AS-HG
6.5
12 / 7
5 m
Micronized grades or aqueous

and dry coating.
1 mm
Granular grades for solventbased coating.
* In Mcllvaine's buffer (citric acidNa2HPO4) and USP Phosphate Buffer (NaOH

KH2PO4)
AQUACOAT CPD - 30
Cellulose Acetate Phthalate aqueous dispersion USP/NF, EP, JP

Aquacoat CPD is a 30 percent solid polymer aqueous dispersion of cellulose acetate phthalate
(CAP) for enteric coating. Enteric coatings allow acid sensitive drugs to pass through the
stomach unaffected or to keep stomach upsetting drugs like aspirin from releasing in the
stomach. Although CAP polymer is hydrophobic, the Aquacoat CPD process allows the product
to be delivered in a totally aqueous pseudo-latex form that is easy to use and clean up, almost
similar to that of solvent coating.
Grade
Description
Aquacoat CPD- A water based pseudo30

latex system
comprising of
Cellulose Acetate
Phthalate
No ammonia used
Application
Enteric coating of tablets and capsules (hard and soft
gelatin). Can also be coated onto beads for filling
into hard gelatin capsules.
AQUACOAT ECD - 30
Ethylcellulose aqueous dispersion USP/NF, EP, JP

Aquacoat ECD is a 30 percent solid polymer aqueous dispersion of ethylcellulose for film
coating of pharmaceutical dosage forms. It is designed for a variety of coating applications to
achieve sustained release, taste-masking and moisture-barrier/sealant coatings. As ethylcellulose
is a hydrophobic polymer, various kinds of release patterns can be achieved by use of suitable
plasticizers, pore formers, etc.
Grade
Description
Application
Aquacoat
ECD-30
A water based pseudolatex system
Sustained release beads for use in capsules / tablets,

moisture barrier / sealant coating and for taste
comprising of
Ethylcellulose, Cetyl
alcohol & sodium
lauryl sulphate. Allows
a wide choice of
plasticizer. No
ammonia used
masking of powders, granules, tablets and capsules.
CALCIUM PHOSPHATES
Calcium phosphates are widely used in pharmaceutical formulations as capsule or tablet diluents.
It has many positive characteristics as an excipient including good compressibility, excellent
stability and white colour. Due to their inherent property of good compatibility, they find use in
both direct compression and wet-granulation process. Two particle size grades of calcium
phosphate are available. The Milled or Powder grade is typically used in wet granulation
process or roller compaction while the Unmilled or Granular grade is used in direct
compression process due to its good flow properties.
Granular grades USP/NF, EP, JP
Grade
Description
Application
A-Tab
Dibasic calcium
phosphate Anhydrous
Tablet and capsule diluent / filler, used in direct

compression. Non-hygroscopic, stable at room
temperature adding to better product stability.
Source of calcium and phosphorous.
Di-Tab
Dibasic calcium
phosphate Dihydrate

compression. Flow agent, blend densifier, tablet
punch polishing agent, time release agent and carrier
of actives. Source of calcium and phosphorous.
Tri-Tab
Tribasic calcium
Phosphate Anhydrous

compression and as filler binder in vitamin
mineral formulations. Also used as a glidant due to
high surface area and carrier of actives. Higher

calcium and phosphorous content.
Tri-Cal WG
Tribasic calcium
phosphate Anhydrous
Special high density grade for use in wet

granulation. Benefits similar as Tri-Tab
CALCIUM PHOSPHATES
Grade
Description
Application
A-Tab
Dibasic calcium
phosphate Anhydrous

Di-Tab
Dibasic calcium
phosphate
Dihydrate
Tablet and capsule diluent / filler, used in

direct compression. Flow agent, blend
densifier, tablet punch polishing agent, time
release agent and carrier of actives. Source

of calcium and phosphorous.
Tri-Tab
Tribasic calcium
Phosphate
Anhydrous

direct compression and as filler binder in
vitamin mineral formulations. Also used as
a glidant due to high surface area and carrier
of actives. Higher calcium and phosphorous
content.
Tri-Cal WG
Tribasic calcium
phosphate
Anhydrous

granulation. Benefits similar as Tri-Tab.
AVICEL CE - 15
Microcrystalline Cellulose and Guar Gum
Avicel CE-15 is a patented combination of Microcrystalline cellulose and Guar gum specially
engineered to improve the organoleptic properties of chewable tablets by providing smoother and
creamier mouthfeel, less grittiness, minimum chalkiness and reduced tooth packing. It can be
used even in direct compression applications and yields softer tablets with reduced friability.
Avicel CE-15 in chewable tablets results in dramatic differences for end users, primarily in the
areas of overall sensory experience and perceived taste, when compared to other tablet binders. It
helps to improve overall patient compliance by improving the formulation palatability.
Grade
Description
Application
Avicel CE-15
Free flowing powder,

co-processed blend
Used for improved mouthfeel / superior sensory

characteristics in chewable tablets.
AVICEL DG
Spray dried compound of Microcrystalline Cellulose and Anhydrous Dibasic Calcium
Phosphate
Avicel DG is a synergistic combination of 75% of Microcrystalline Cellulose and 25% of

Anhydrous Dibasic Calcium Phosphate produced using spray dried, co-processing technology.
Avicel DG offers good flow characteristics, a high quality initial compactability, required for the
production of robust ribbons, and excellent recompactability, resulting in enhanced tabletting
performance and fewer rejected tablets.
Grade
Description
Application
Avicel DG
White, odourless
uniform particle size
powder
Dry granulation binder for roller compaction

process
AVICEL HFE - 102

Spray dried compound of Microcrystalline cellulose and Mannitol
Avicel HFE-102 is a novel, proprietary, co-spray dried Microcrystalline cellulose (MCC) and
Mannitol excipient for direct compression. The co-processing of MCC and Mannitol creates a
synergistic functionality, providing superior benefits compared to the use of individual or dryblended components.
Avicel HFE-102 is a highly compactible excipient and exhibits improved flow, superior
compactibility and better disintegration properties compared to traditional MCC grades. The
product also exhibits less sensitivity to lubrication.
Grade
Description
Application
Avicel HFE-
Medium particle size
High functionality excipient for direct compression
102
powder
of tablets, chewable tablets, fast dissolving tablets,

MUPS technology tablets etc. Helps accelerate
tablet development, reduces sensitivity to lubricant
thus enabling higher lubricant levels to reduce
sticking problems in full-scale production.
Avicel PH
Microcrystalline Cellulose USP/NF, EP, JP
Avicel PH is the innovators brand of microcrystalline cellulose. It is a purified, partially depolymerized alphacellulose made by acid hydrolysis of speciality wood pulp controlled to a stringent degree of polymerization than
required by global pharmacopeia.
The unique properties of Avicel PH makes it an indispensable formulation tool and excipient of choice in direct
compression applications on account of its superior compactibility, drug carrying capacity and rapid disintegration.
These properties also benefit dry granulation process such as roller compaction or slugging. When used in wet
granulation process, Avicel reduces the risk of over-granulation, avoids screen blockage and promotes uniform,
rapid drying. Avicel PH is an excellent extrusion-spheronization binder. The inclusion of Avicel PH in capsule
formulations improves flow, facilitates plug formation and aids capsule disintegration.
Avicel PH continues to set new standards with enhanced grades designed to boost productivity and meet any
formulation challenge.
Grade
Description
Application
Avicel PH
101
Fine particle size
For conventional applications, specially in

wet granulation and roller compaction.
Avicel PH
102
Medium particle size For improved flow in direct compression, dry

phase of wet granulation and dry
granulation.
Avicel PH
103
Low moisture with

fine particle size
Well suited for moisture sensitive actives.
Avicel PH
105
Extra fine particle

size
For use in direct compression of coarse or

hardtocompress materials.
Avicel PH
112
Very low moisture

with medium
particle size
Best for direct compression of moisture

sensitive actives with increased flow.
Avicel PH
113
Very low moisture

with fine particle
size
Improves product stability by extending the

shelf life, particularly of moisture sensitive
actives.
Avicel PH
200
Largest particle size
For best flow in direct compression and dry

granulation applications while maintaining
high levels of compressibility with minimum
weight variation and content uniformity
issues.
Avicel PH
200 LM
Very low moisture

with largest particle
size
Best for direct compression of moisture

sensitive actives with superior flow rate than
PH 112.
Avicel PH
301
High bulk density

with fine particle
size
For manufacture of small tablets. reduces

powder stratification and tablet weight
variation by efficient mixing.
Avicel PH
302
High bulk density

with medium
particle size
For manufacture of thin tablets despite high

API content. Prevents powder segregation
and gives good flow.
AVICEL RC/CL
Microcrystalline Cellulose and Carboxymethylcellulose Sodium USP/NF, BP, JPE
Avicel RC/CL are water dispersible, colloidal, spray dried blends of microcrystalline
cellulose and carboxymethylcellulose sodium used in pharmaceutical suspensions,
emulsions, nasal sprays and creams. Avicel RC / CL products produce highly
thixotropic, low viscosity, structured vehicles that yield desirable permanent
suspensions without settling or sedimentation. It also eliminates lengthy hydration
time while increasing formulation stability.
When used in reconstitutable suspensions, Avicel RC / CL facilitates hydration of the dry mix.
Avicel dispersions are stable to heat and freeze/thaw over a wide pH range. Avicel thixotropy
reduces the clearance of nasal spray formulations. It is an excellent stabilizer for oil-in-water
emulsions, reducing oil droplet movement and coalescence. The wide range of thixotropies,
viscosities, gel strengths, and dispersion characteristics of this product line provide unparalleled
suspension stability and functional versatility.
Grade
Description
Application
Avicel RC-581
Bulk dried powder

requiring high shear
mixing for dispersion
Conventional suspending agent and dispersion aid.
Avicel RC-591 Spray dried powder

requiring low shear
mixing for
dispersion
Used for oral suspensions, nasal sprays,

topical sprays, lotions, liquid and semi-solid
dosage forms. Provides a structured
dispersion vehicle, acts as a protective colloid
and facilitates dispersion.
Avicel CL-611 Spray dried powder

requiring low shear
mixing for
dispersion. Has
more CMC content
Recommended for reconstitutable / dry

suspensions. Also for oral suspensions.
BLANOSE
Sodium Carboxymethylcellulose USP/NF, EP, JP
BLANOSE, Carboxymethylcellulose Sodium is the sodium salt of
carboxymethylcellulose (CMC) which is an anionic, water-soluble polymer derived
from cellulose reacted with sodium monochloroacetate. BLANOSE is soluble in cold
or hot water, insoluble in organic solvents, compatible with water / alcohol systems
& imparts low water and oxygen transmission to coatings.
BLANOSE grades find application as thickeners, binders, stabilizers, suspending agents and
rheology modifiers. The grades designated P or PH are purified grades which meet
pharmaceutical standards. A wide range of substitution types are also available, based on number
of carboxymethyl groups present on the cellulose backbone. The low substitution grades (7
types) provide thixotropy whereas the higher substitution grades (9 and 12 types) provide smooth
solutions without thixotropy.
Grade
Viscosity in mPas
(% w/w)*
Application
Blanose 7H4F- 2500 - 4500 (1%)

PH
Tablet coatings - Film former
Blanose 7HFPH
Mucoadhesives - Absorbency
1500 - 2500 (1%)
Blanose 7MF- 400 - 600 (2%)

PH
Syrups & Suspensions - Thickener & suspending

agent
Blanose
7M1F-PH
50 - 100 (2%)
Sustained Release - Thickener, diffusion barrier
Blanose 7LFPH
25 - 50 (2%)
Blanose
9M31F-PH
1500 - 3100 (2%)
Blanose
9M8F-PH
400 - 800 (2%)
Blanose
12M8P
200 - 800 (2%)
Blanose
12M31P
1500 - 3100 (2%)
Bulk Laxative - Inert, high water binding agent
Ointments, Creams & Lotions - Stabilizer,

thickener, film former
*Also avaialbe in finely (X) ground grades.
*Viscosity in milli Pascal per second (mPas or cps) determined on aqueous solutions as per indicated weight %. at 250 C + 0.50 C
using a Brookfield SyncroLectric LVF viscometer.
DSType
Substitution
range
Sodium content, %
0,65 to 0,90 **
7,0 - 8,9
0,80 to 0,95
9,2 - 9,3
12 (for USP
grades)
1,15 to 1,45
10,4 - 12,0
12 (for EP
grades)
1,12 to 1,21
10,2 - 10,8
Cellulose Acetate
Non-enteric celluose ester
Cellulose Acetate is cellulose in which a portion or all of the hydroxyl groups are acetylated. It is
prepared from highly purified cellulose by treatment with acid catalysis and acetic anhydride. It
occurs as a white, odourless, tasteless, free-flowing powders. They are mainly used for sustained
release applications and taste masking.
Cellulose Acetate is used as a semi-permeable coating on tablets, especially on osmotic pumptype tablets and implants. This allows for controlled, extended release of actives. Cellulose
acetate films, in conjunction with other materials, also offer sustained release without the
necessity of drilling a hole in the coating as it is typical with osmotic pump systems. Cellulose
acetate and other cellulose esters have also been used to form drug-loaded microparticles with
controlled-release characteristics.
Grade
Description
CA-320-S
Water insoluble powder Used in controlled-release applications as water

with viscosity of 170 permeable membrane in osmotic systems; direct
280 cps in pyridine.
compression matrix component; barrier component
in taste masking.
CA-398-10
Water insoluble
powder of low
viscosity solution
CALCIUM PHOSPHATES
Application
Used for oral sustained release matrix drug

delivery and in film coating applications.
processes or roller compaction while the Unmilled or Granular grade is used in direct
compression processes due to its good flow properties.
Powder grades USP/NF, EP, JP
Grade
Description
Application
Calipharm A
Dibasic calcium
phosphate Anhydrous
Filler in wet granulation, multivitamin chewable

tablets and nutritional drinks.
Calipharm D Dibasic calcium

phosphate
Dihydrate.
Filler in wet granulation, vitamin premixes

and nutritional drinks.
Calipharm T
Filler in wet granulation, particularly antacid

formulations for its buffer action. Also used in
nutritional drinks and calcium / phosphorous
fortifications.
Tribasic calcium
phosphate
Anhydrous
STURCAL L & CALOPAKE Extra Light

(Precipitated) Calcium Carbonate USP/NF, EP, JP
Precipitated Calcium Carbonate (PCC), alternatively known as purified, refined or synthetic

calcium carbonate is produced by direct carbonation of hydrated lime by a simple process called
Milk of lime process. The process involves combining lime (CaO) with water to form slaked
lime, addition of carbon dioxide and precipitation of calcium carbonate in a very fine, white
form. The precipitated calcium carbonate is then washed, purified, dried and packaged.
Specialty Minerals Inc. uses high quality limestone sources for its PCC products, including some
from the 150 year old SMI limestone mine in Adams, Massachusetts. Although a number of
different calcite crystal forms are possible, Sturcal L & Calopake Extra Light consist of
agglomerates of scalenohedral calcite crystals. The two grades differ in particle size and apparent
densities and are compliant as per USP/NF, EP & JP.
Grade
Description
Media
n
Partic
le size
(m)
Application
Sturcal L
Heavy grade, apparent

density: 0.78 0.96
75
Used mainly in antacid tablets and

liquids, in dentifrices &
therapeutically as calcium
supplement in pharmaceuticals &
fortified foods.
Calopake
Extra Light
Extra light grade,

apparent density: 0.42
0.50
45
Used as abrasive in dentifrice

products, for calcium
supplementation in nutritional
and pharma products, also as
antacid, pH modulator and
flocculent.
CASTER SUGAR
Screened Sucrose USP/NF, EP, JP
Sieved sucrose or screened sucrose is obtained by purification and crystallization of juice

extracted from sugar beet and subsequently screening it continuously. It is a highly pure
crystalline powder recommended for applications requiring high quality clear solutions or for
coatings.
Grade
Description
Application
Caster Sugar
250
Extremely pure,
Ideal for dry syrups, suspensions, granulation and
crystalline powder with coating. Facilitates dissolution and ensures
low dispersion particle homogenous mixture.
size. Dust free and free
flowing
Caster Sugar
400
Highly pure, fine

grain crystalline
powder. Dust free
and free flowing
Facilitates preparation of dry syrups, liquid

syrups due to higher dissolution rate than
crystal sugar. Also used for coating.
CELLULOSE ACETATE PHTHALATE (C-A-P)

Cellacefate USP / NF, EP, JP
C-A-P is a cellulose in which about half the hydroxyl groups are acetylated, and about a quarter
are esterified with one of two acid groups being phthalic acid, where the remaining acid group is
free. It is a pH-sensitive cellulose derivative designed for enteric coating of pharmaceutical
dosage forms like tablets or granules. It can also be used for matrix drug delivery.
C-A-P can withstand prolonged contact with acidic gastric fluids while being able to dissolve
readily in the mildly acidic to neutral environment of the small intestine. C-A-P is commonly
applied to solid-dosage forms either by coating from organic or aqueous solvent systems or by
direct compression. C-A-P is compatible with many plasticizers and the addition of plasticizers
improves the water resistance of this coating material thus making the formulations more
effective.
Grade
Form
Application
C-A-P Pellets
White pellets
C-A-P Powder
White powder
Used as enteric film coating material for solid

dosage forms like tablets, pellets and capsules. Also
used as a matrix binder.
CELPHERE
Microcrystalline Cellulose USP/NF, EP, JP, JPE
Celphere represents 100% pure microcrystalline cellulose (MCC) spheres or seed cores and is a
product of cellulose particle research, development and process technology at Asahi Kasei. It is
used in manufacturing of granules for sustained / controlled release, taste masked and other
special properties.
Celphere enables greater accuracy and consistency in drug layering and coating as it is highly
spherical, has narrow particle size distribution and exhibits optimum water absorption. It has low
chemical reactivity and hence can be freely used to layer high dose, moisture sensitive & potent
actives. Its high mechanical strength and low friability allows it to withstand the rigors of
fluidized bed or wurster coating process. It is conveniently available in various particle size
grades ranging from 75 to 850 m.
Grade
Particle size
range (m)
Application
Celphere SCP100
75 - 212
Celphere CP102
106 - 212
Used as spherical seed cores for drug layering &

film coating. Also used in manufacture of granules /
beads with sustained / controlled release, taste
masking & other special properties.
Celphere CP203
150 - 300
Celphere CP305
300 - 500
Celphere CP507
500 - 710
Celphere CP708
710 - 850
CEOLUS KG / UF
Microcrystalline Cellulose USP/NF, EP, JP
Ceolus KG / UF are super-compactibility Microcrystalline Cellulose (MCC) powder grades. The

unparalleled compactibility is attributed to its distinctive rod-form particle configuration. Ceolus
KG / UF grades thus enable lowest friability, reduced compression force, low addition rate and
reduced tablet size. Even at 5% addition, they are very effective.
Ceolus KG / UF finds use in direct compression, wet granulation, roller compaction as well as
for adsorption of oily actives for direct compression. They occupy a unique position among dry
binders in its combination of three salient performance characteristics far higher
compactibility, together with an optimum balance of powder flowability and tablet
disintegration.
Grade
Particle size (m) Application
CEOLUS KG
802
Effective in tableting of high dose actives, poorly

compressible actives, pressure -sensitive actives,
coated granules / pellets and orally disintegrating
tablets. It is ideal in formulations based on MUPS
(Multiple unit particulate systems) technology.
50
CEOLUS KG
1000
CEOLUS UF
711
Similar applications like KG grades. However,

flow is more superior compared to KG types.
COMPRESSUC
Spray Dried Sugars USP/NF, EP, JP
Compressuc represents a new generation of sugar for direct compression, produced from an
innovative and patented spray drying process. Anhydrous, fully soluble in water with a sweet
taste; Compressuc is probably one of the most efficient excipient available on the market for
direct compression tabletting.
Grade
Description
Application
Compressuc
MS
Directly compressible
sucrose with
maltodextrins /
inverted sugar.
Excellent diluents, binder for direct compression of

chewable, effervescent and orodispersible tablets.
Has remarkable free-flow, mixing, compaction
properties.
Also used in sachet fillings and dry syrups.
Compressuc
PS
Directly
compressible pure
sucrose (without
additives)
CREMOPHOR
Non-ionic solubilizers / Emulsifiers
Cremophor RH 40 is a non-ionic solubilizer and emulsifying agent obtained by reacting 45

moles of ethylene oxide with one mole of hydrogenated castor oil.
Cremophor EL is a non ionic solubiliser and emulsifier made by reacting castor oil with ethylene
oxide in a molar ratio of 1:35. Cremophor ELP is a purified grade of Cremophor EL specially
developed to give stable formulations of sensitive APIs, especially in injectable form.
The Cremophor A types are prepared by reacting higher saturated fatty alcohols with ethylene
oxide, with the degree of ethoxylation being indicated by the numeral in the name.
Grade
Pharmacopo
eial Name
Appearance
Cremophor RH Polyoxyl-40
White to yellowish,
Hydrogenated nearly odourless,
40
Castor Oil
tasteless, paste
Application
Used to solubilize vitamins,

hydrophobic actives, and
essential oil-in-water or
hydroalcoholic
mixtures, to improve
bioavailability in solid
dosage forms and as solubilizer
in oral / topical liquid and semiliquid dosage forms.
Cremophor
EL
Polyoxyl-35
Castor Oil
(Standard
grade)
Pale yellow oily liquid
Cremophor
ELP
Polyoxyl-35
Castor Oil
(Extra pure
grade of EL).
White to yellowish
paste or cloudy liquid
Used as solubilizer and

emulsifier in
liquid formulation for oral,
topical and parenteral use.
Cremophor A
6
Macrogol-6cetostearyl
ether
Whitish waxy
substance
Cremophor A
25
Macrogol-25cetostearyl
ether
Free flowing,
nondusting micro
beads
Non-ionic emulsifiers used

for production of ointments,
creams, gels based on oil-in
water
emulsions / water-in-oil
emulsions. Also used
for emulsification of
hydrophobic APIs to
form very stable oilinwater
emulsions.
CRYSMEB
Methyl Betacyclodextrin
Kleptose Crysmeb is a new generation, low metylated betacyclodextrin which is a purified

polydisperse product resulting from the controlled reaction of a methylation agent and native
betacyclodextrin. This unique patented product of Roquette has good water solubility, enhanced
stability to form inclusion compounds and a good potential for biological tolerance.
Grade
Description
Application
Crysmeb
Methyl
Betacyclodextrin with
low molar substitution
Suitable for encapsulation of low solubility, volatile

or unstable active ingredients. Used for injectables,
syrups, solutions and oral suspensions.
GLUCOSE
Dextrose USP/NF, EP, JP
Glucose or Dextrose is the monomer of natural starch polymer. It is white,

odourless, sweet, in crystalline or granular powder form and freely soluble in water.
This monomer is also the natural physiological sugar in the human body. In its
crystalline form this doubly natural sugar has long been used both as a filler for oral
dosage forms and as a sweetener. It also helps in improving the stability of API
sensitive to oxidation due to its slight reducing properties. Therapeutically it is used
as a preferred source of carbohydrate in parenteral nutrition.
Roquette has a range of dextrose products wide enough to meet any of
manufacturers different requirements.
Grade
Description
Application
Lycadex PF
Pyrogen free dextrose

monohydrate
Osmotic agent in injectables and dialysis solutions,

for parenteral nutrition and treatment of
hypoglycemia.
Dextrose
Pyrogen free
Anhydrous PF dextrose anhydrous
Dextrose GC
Agglomerated
dextrose
monohydrate
Direct compression diluent with excellent

compressibility and flowability for use in
tablets, sachets and capsule formulations.
Roferose
Dextrose
Monohydrate
Diluent for tablets, capsules and sachets.
Dextrose
Crystalline dextrose
Anhydrous C
anhydrous
Roclys
Dextrose syrup
without extensive
hydrolysis
Flolys
Dextrose syrup with

extensive hydrolysis
For inhibiting sucrose crystallization as

texturizer and bulk sweetener in syrups,
lozenges, pastilles and pharmaceutical
chewing gums.
CALCIUM PHOSPHATES
Calcium phosphates are widely used in pharmaceutical formulations as capsule or tablet

diluents. It has many positive characteristics as an excipient including good compressibility,
excellent stability and white colour. Due to their inherent property of good compatibility, they
find use in both direct compression and wet-granulation process. Two particle size grades of
calcium phosphate are available. The Milled or Powder grade is typically used in wet
granulation process or roller compaction while the Unmilled or Granular grade is used in
direct compression process due to its good flow properties.
Grade
Description
Application
A-Tab
Dibasic calcium
phosphate Anhydrous

Di-Tab
Dibasic calcium
phosphate
Dihydrate

direct compression. Flow agent, blend
densifier, tablet punch polishing agent, time
release agent and carrier of actives. Source
of calcium and phosphorous.
Tri-Tab
Tribasic calcium
Tri-Cal WG
Phosphate
Anhydrous
direct compression and as filler binder in

vitamin mineral formulations. Also used as
a glidant due to high surface area and carrier
of actives. Higher calcium and phosphorous
content.
Tribasic calcium
phosphate
Anhydrous

DOCUSATE SODIUM USP/NF, EP

Dioctyl Ester of Sodium Sulfosuccinate (DSS)
Docusate Sodium (DSS) enjoys the reputation of being one of the most versatile and
effective anionic surfactants (surface active agents) used by the Industry. It has
excellent wetting, solubilizing, dispersing and emulsifying properties allowing it to
be used in a multiplicity of applications in pharmaceutical formulations especially in
oral dosage forms. Cytecs DSS is of exceptionally high purity and has a valid Drug
Master File no. with the USFDA.
DSS is virtually free from adverse reactions, non habit-forming and causes the least
possible disturbance of normal body physiology. It is effective alone or in
combination with peristaltic stimulants and bulking agents in the treatment of
constipation. It is also an effective wetting agent in topically applied medical
preparations like creams, lotions and ointments.
Grade
Description
Application
Docusate Sodium
(100 %)
Rolls of white wax- Aids the granulation process, improves tablet

disintegration and dissolution, facilitates
like plastic sheets
Docusate
Sodium (85%)
with Sodium
Benzoate (15%)
White crystalline
powder
Docusate
White to yellow,
tablet coating, emulsifies gels & suspensions.
Also used in laxatives and stool softeners,

prenatal and geriatric vitamin preparations,
colon cleansing aids (used before Xray or
surgery) and in ear wax removal formulations.
Sodium (50%) in
Polyethylene
glycol (50 %)
clear viscous
liquid
DUB DBHG
Glyceryl Dibehenate EP
Glyceryl Behenate is prepared by the esterification of glycerin by behenic acid

without the use of catalysts. It is a mixture of diacylglycerols, mainly
dibehenoylglycerol, together with variable quantities of mono and triacylglycerols. It
is generally regarded as a relatively non-irritant and non-toxic material.
Grade
Description
Application
DUB DBHG
Fine, micronized
powder with a faint
odour
Used as lubricant for tablets. Also can be used as

lipidic matrix for sustained release.
DUB DBS
Dibutyl Sebacate USP/NF
Dibutyl Sebacate is manufactured by the esterification of n-butanol and sebacic

acid in the presence of a suitable catalyst, and by the distillation of sebacic acid
with n-butanol in the presence of concentrated acid. DUB DBS is stable and is not
reactive with water and thus hazardous polymerization does not occur. However it
is incompatible with strong oxidizing materials and strong alkalis.
Grade
Description
Application
DUB DBS
Clear, colorless, oily
Used in oral pharmaceutical formulations as a
liquid with a bland to

slight butyl odour.
plasticizer for film coatings on tablets, beads and

granules, in controlled-release tablets and
microcapsule preparations.
DUB MCT
Medium Chain Triglycerides USP/NF, EP
Medium chain triglycerides are a class of fatty acids obtained by esterification of

glycerol with mixtures of caprylic and capric fatty acids which are fractionated from
coconut or palm kernel oils. They are specially processed to achieve superior
oxidative stability and low colour and then are further refined to remove residual
fatty acids resulting in a product with no odour or flavor.
Their chemical composition is of a shorter length than the long-chain fatty acids
present in most other fats and oils. They are also different from other fats as they
have a slightly lower calorie content and are more rapidly absorbed and
metabolized as energy resembling a carbohydrate more than fat. The unique
metabolic and functional properties, a consequence of their chemical structure
make them versatile ingredients in a number of pharmaceutical and food
formulations.
Grade
Description
Application
DUB MCT
5545
Oily liquid
Energy source for patients with fat

malabsorption syndrome. Used as plasticizer,
tablet lubricant and as a liquid base for
parenterals. Also used as low calorie fats in
diet preparations and in capsule filling.
DUB MCT
7030
DUB MCT
6535
DUB MICROLUB
Stearic Acid USP/NF, EP
Stearin or Stearic acid is a mixture of stearic acid and palmitic acid derived from an
edible source. The content of stearic acid is not less than 40% while that of palmitic
acid is also not less than 40% and the sum of the two not less than 90%. It occurs
as a hard, white or faintly yellowish, somewhat glossy, crystalline solid or as white
or yellowish white powder, with a faint odor and taste, suggesting tallow.
Grade
Description
Application
DUB
MICROLUB
70
Stearic Acid 70% Micronised powder
Used as a tablet lubricant. Micronized grade

imparts a smooth, shiny surface to film
coated tablets. Also used as emulsifying and
solubilizing agent in topical formulations like
ointments and creams.
DUB
Stearic Acid 50% MICROLUB 50 Micronised powder
Also available is STEARIC ACID 95% (in flakes form) and STEARIC ACID 50% (in pellets or powder form)
DUB PP
Hemi-synthetic Glycerides USP/NF, EP
DUB PP are hard fat suppository bases and are a mixture of triglycerides,
diglycerides and monodiglycerides which may be obtained either by esterification of
natural fatty acids with glycerol or by inter-esterification of natural fats. Each type of
hard fat is characterised by its melting point, its saponification value and its
hydroxyl value. These suppository bases, DUB PP, are made from vegetable fatty
acids. They are presented in non-toxic, neutral pellet form allowing for easier use.
Moreover, they do not contain any oxidizing or stabilizing agent.
Grade
DUB PP C 3
Saponificatio
n
Value
Melting Point
(C)
Hydroxyl
Value
Applicatio
n
230 240
33 35
20 30
Multipurpo
se
DUB PP CDL 1
225 245
33.5 35.5
15
DUB PP D 1
234 247
34 36
10
DUB PP E 1
235 245
35 36.5
10
DUB PP E 3
235 245
35 36.5
20 30
DUB PP F 1
235 245
36 37.5
10
DUB PP H 1
230 240
38 40
10
DUB PP M 1
223 233
42 44
10
DUB PP KC 3
225 240
33.5 35.5
20 30
DUB PP KCD 1
235 245
33.5 35.5
15
DUB PP KD 3
225 240
34 36
20 30
DUB PP KE 3
215 236
Ac-Di-Sol SD711
20 30
DUB PP KF 1
235 250
35.5 37.5
15
Suppositor
y Bases
Specific
Suppositor
y Bases
DUB SE
Sucrose Esters USP/NF, EP
Sucrose esters are natural surfactant materials obtained by the esterification of one
or more of the hydroxyl groups of the sucrose molecule with vegetable fatty acids.
These compounds are non-ionic and have excellent emulsifying, wetting and
dispersing properties. By modifying the esterfication degree of the sucrose, it is
possible to obtain a range of different emulsifiers with HLB from 3 to 16.
Sucrose esters are tasteless, odorless and non-toxic. They are non-irritant, mild to
the skin and find use in pharmaceuticals, cosmetics and foods.
Grade
Description
Application
DUB SE 3S
Sucrose Tristearate
DUB SE 5S
Sucrose Distearate
DUB SE 11S
Sucrose Stearate
Low HLB grades used as tablet / capsule lubricant

while high HLB grades are used to make easy
dispersible tablets. Also used as a solubilizer, foam
enhancer and as an emulsifier - stabilizer in oil-inwater emulsions. Their nonionic nature makes them
co-emulsifiers as well.
DUB SE 15P
Sucrose Palmitate
DUB SE 16P
Sucrose Palmitate
AQUALON ETHYL CELLULOSE PHARM

Ethylcellulose USP/NF, EP, JP
AQUALON EC is a non-ionic ethyl ether of cellulose, soluble in a wide range of

organic solvents. Typically, ethylcellulose is used as a non-swellable, insoluble
component in matrix or coating systems. When water soluble binders cannot be
used in dosage processing because of water sensitivity of the active ingredient,
ethylcellulose is often chosen.
Ethylcellulose can be used to coat one or more active ingredients of a tablet to
prevent them from reacting with other materials or with one another. It can prevent
discoloration of easily oxidizable substances such as ascorbic acid, allowing
granulations for easily compressed tablets and other dosage forms. Ethylcellulose
can be used on its own or in combination with water-soluble polymers to prepare
sustained release film coatings that are frequently used for the coating of microparticles, pellets and tablets.
Grade
Viscosity in mPas
(% w/w)*
Application
EC N 7 Pharm
6 to 8
Microencapsulation - Stabilizes against active
EC N 10
Pharm
8 to 11
EC N 14
Pharm
12 to 16
EC N 22
Pharm
18 to 24
EC N 50
Pharm
18 to 24
EC N 100
Pharm
80 to 105
EC T 10
Pharm
8 to 11
interactions, hydrolysis and oxidation.

Tablet coating Film coating for sustained release.
Tablet Binder - Plastic flow, suitable for direct
compression, injection molding and melt extrusion.
Taste Masking - improved taste through suppression
of bitter taste & strong odours of actives.
Directly compressible, micronized grade with

high ethoxyl content and low viscosity for
optimum compactibility and good powder
flow. Eliminates the need for solvents in
direct compression controlled release
matrices.
* Determined using 5% ethyl cellulose solution (by weight) in 80 parts toluene & 20 parts ethanol
GLUCOSE
Glucose or Dextrose is the monomer of natural starch polymer. It is white,

odourless, sweet, in crystalline or granular powder form and freely soluble in water.
This monomer is also the natural physiological sugar in the human body. In its
crystalline form this doubly natural sugar has long been used both as a filler for oral
dosage forms and as a sweetener. It also helps in improving the stability of API
sensitive to oxidation due to its slight reducing properties. Therapeutically it is
used as a preferred source of carbohydrate in parenteral nutrition.
Roquette has a range of dextrose products wide enough to meet any of
manufacturers different requirements.
Grade
Description
Application
Lycadex PF

monohydrate

hypoglycemia.
Dextrose
Pyrogen free
Anhydrous PF dextrose anhydrous
Dextrose GC
Agglomerated
dextrose
monohydrate
Direct compression diluent with excellent

compressibility and flowability for use in
tablets, sachets and capsule formulations.
Roferose
Dextrose
Monohydrate
Diluent for tablets, capsules and sachets.
Dextrose
Anhydrous C
anhydrous
Roclys
Dextrose syrup
without extensive
hydrolysis
Flolys
Dextrose syrup with

For inhibiting sucrose crystallization as

texturizer and bulk sweetener in syrups,
lozenges, pastilles and pharmaceutical
chewing gums.
Marine Colloids Carrageenan

Carrageenan USP/NF
Carrageenan is a family of naturally-occurring high molecular weight

polysaccharides extracted from red seaweed. The main seaweed types include
Eucheuma, Chondrus and Gigartina which yields kappa, iota and lambda
carrageenan.
The carrageenan structure is made up of repeating galactose and 3,6
anhydrogalactose units, both sulfated and non-sulfated joined by alternating alpha
1-3 and beta 1-4 glycosidic linkages.
The kappa, iota and lambda carrageenans differ in properties mainly due to the
number and position of ester sulphate groups on the galactose units. While kappa
forms a brittle gel, iota forms an elastic gel and lambda does not form a gel. Based
on their properties, they find use as stabilizers, thickeners, suspending agents,
gelling agents and flow regulators in pharmaceutical dosage forms.
Description
Grade
Application
Carrageen
an Type
Viscosity
Gel Type
Gelcarin GP-379
Iota
High
thixotropic
Elastic,
Medium
strength
Creams and
suspensions. Is polyol
and protein reactive.
Promotes freeze thaw.
Gelcarin GP-812
Kappa
Low
Brittle,
Strong
Gives stronger gels

than GP 911 with
higher syneresis.
Gelcarin GP-911
Kappa
Low
Brittle, Firm
Used in encapsulation /
delivery systems. Is
polyol and protein
reactive.
Viscarin GP-109
Lambda
Medium
Nongelling
Used in creams and

lotions. Is polyol and
protein reactive.
Viscarin GP-209
Lambda
High
Nongelling
Used in creams and

lotions. Is polyol and
protein reactive.
SeaSpen PF
Iota
Medium
thixotropic
Elastic,
Weak
Used in suspensions,
reconstitutables, topical
lotions and creams.
GLUCIDEX
GLUCIDEX is a large family of maltodextrins and dried glucose syrups, obtained

from starch by hydrolysis, followed by purification and spray drying. Glucidex
grades exhibit good stability and range from slightly sweet-to-sweet products.
Depending on the grade used, GLUCIDEX products can help adjust and control the
properties of viscosity and texture, sweetness, anti-crystallizing power, browning
reactions, fermentability and freezing point depression.
GLUCIDEX Maltodextrins
Maltodextrin USP/NF, EP
Maltodextrins are dried starch hydrolysis products with a dextrose equivalent (D.E.)
lower than 20. These are fine white, neutral or slightly sweet tasting powders,
soluble in water and with a high standard of organic, mineral and bacteriological
purity.
Grade
Description
Application
Glucidex 2 D
Maltodextrin with
dextrose
equivalent of
maximum 5
Diluent for tablets, capsules, sachets, carrier for

spraydrying, carbohydrate source in infant and
enteral foods. Can also be used for DC formulations
of vitamins or
mineral supplements.
Glucidex 6 D
Maltodextrin with
dextrose
equivalent of 5 to 8
Glucidex 9 D
Maltodextrin with
dextrose
equivalent of 8 to
10
Glucidex 12 D Maltodextrin with

dextrose
equivalent of 11 to
14
dextrose
equivalent of 15 to
18
dextrose
equivalent of 18 to
20
Note: Also available in IT grades with free flow properties and better solubilization due to its particular physical structure.
GLUCIDEX Dried glucose syrups

Corn syrup solids USP/NF, EP
Corn syrup solids (earlier known as dried glucose syrups) are dried starch hydrolysis
products with a Dextrose equivalent (DE) greater than 20. They have greater
sweetness as compared to maltodextrins. These are fine white, neutral or slightly
sweet tasting powders, soluble in water and with a high standard of organic, mineral
and bacteriological purity.
Grade
Description
Application
Glucidex 21 D
Dried glucose syrup

with dextrose
equivalent of 20 to 23
Diluent for tablets, capsules, sachets, carrier in

spraydrying, carbohydrate source in infant and
enteral foods.
Glucidex 33 D Dried glucose syrup

with dextrose
equivalent of 31 to
34
Glucidex 47 D Dried glucose syrup
with dextrose
equivalent of 43 to
47
Note: Also available in IT grades with free flow properties and better solubilization due to its particular physical structure.
GLYCOLYS
Sodium Starch Glycolate USP/NF, EP, JPE
Sodium Starch Glycolate is the sodium salt of cross-linked carboxymethyl ether of

starch. It is a white-to-off-white, odourless, tasteless, free flowing powder which is
sparingly soluble in 95% ethanol and practically insoluble in water. GLYCOLYS is
potato starch based and has the capacity to swell upto 300 times its original
volume in water, a property that attributes to its use as a superdisintegrant.
Roquette has been producing SSG for more than 20 years now and has developed
different grades of GLYCOLYS to meet the specific needs of viscosity, moisture, pH or
solvent-free properties.
Grade
Description
Application
Glycolys
Standard grade SSG Type A
Super disintegrant for solid dosage forms. Used in

both wet granulation and direct
compression processes.
Glycolys LV
Low viscosity grade

SSG - Type A
Designed to withstand high shear in wet

granulation processes.
Glycolys LM
Low moisture grade

SSG - Type A
For moisture sensitive actives.
Glycolys Low
pH
Acid stable grade

SSG - Type B
Designed to resist acidic pH and stabilize

products containing strongly acidic drugs.
HI-SWEET
High Fructose Corn Syrup (HFCS)
High Fructose Corn Syrups (HFCS) products are sweet, clear, clean-tasting, odorless
liquids manufactured by controlled hydrolysis of starch polymers thus resulting in
high fructose compositions with valuable bulk sweetening profiles. Roquette offers
two grades of HFCS differing in sweetness and viscosity.
Grade
Description
Hi-Sweet 55
Used as a bulk sweetener and viscosity

Solid content of
minimum 55% fructose enhancer in medicated syrups and
suspensions. Provides high sweetness and
on dry basis.
Hi-Sweet 42
Solid content of
Application
clean mouth feel compared to sucrose and

invert sugar.
minimum 42%
fructose on dry
basis.
HPMCP
Hypromellose Phthalate USP/NF, EP, JP
Hypromellose Phthalate (Hydroxypropyl Methylcellulose Phthalate) is a phthalic half

ester of Hypromellose and the threshold pH value for rapid disintegration of HPMCP
can be controlled by varying the phthalyl content.
HPMCP is a solvent based enteric coating agent used to protect drugs from gastric
degradation or to protect the gastric mucosa from irritant drugs.
Two types of HPMCP are available based on the pH solubility, HP-50 and HP-55.
Additionally, there is a special type viz, HP-55S which has a higher molecular weight
and gives films of greater strength and gastric resistance.
Grade
Description
Dissolving pH*
HPMCP HP50
Viscosity (cst)
40
HPMCP HP55
HPMCP HP
55S
Application
5.5
5.0
170
55
* In Mcllvaine's buffer solution (citric acidNa2HPO4) and Clark-Lubs buffer solution
ICING SUGAR
Milled Sucrose USP/NF, EP, JP
Regular grade
Greater film strength
Soluble at low pH
Icing Sugar is obtained by continuous grinding of sugar crystals. The range of icing
sugar is particularly adapted to any use requiring a finely milled and high purity
sugar.
Grade
Description
Application
Icing Sugar
Pure
Very fine powder,

impalpable (100%
sucrose)
Used for granulation, coating and in sachets.

Easily compressible and dissolves quickly in
water than regular sugar.
Icing Sugar
with Starch
Very fine powder,

impalpable (with
maize starch added
as an anti-caking
agent)
ALGINATES and ALGINIC ACIDS USP/NF, EP, JP
Alginates are natural hydrocolloids of vegetable origin that occur as a structural

component in marine brown algae, where they give strength and flexibility to the
plant. In contrast to most other polysaccharide gels, alginate gels can develop
instantaneously in the presence of divalent cations into acid gels at low pH and
constant temperature. The gelling gives rise to a three dimensional network which
determines the gel strength. Alginates with high content of G-blocks give stronger
gels & M-rich alginates give softer and more fragile gels. The molecular weight
determines the viscosity of alginate solutions while the ratio of mannuronic acid
guluronic acid (M/G) determines the relative strength of the gel.
FMC range of alginates and alginic acids offer unique gel-forming, film-forming,
thickening and stabilizing properties.
Grade
Description
Alginate Type
Protacid F 120
NM
Alginic Acid
Application
Viscosity (mPas)
-
Used in antireflux and

effervescent tablets. Also as a
Kelacid
Alginic Acid
Alginic Acid
DC
Alginic Acid,
Directly
Compressible
Protanal LFR
5/60
Sodium
Protanal LF
Mg 5/60*
Magnesium
Manugel LBA
Sodium
300-700 (10%)
Manugel LBB
Sodium
8000 (10%)
Protanal LF
240 D
Sodium
70 200 (1%)
Protanal LF
120 M
Sodium
70 150 (1%)
Keltone LVCR
Sodium
35 (1%)
Keltone HVCR Sodium
300 700 (10%)
AntiReflux Suspensions (Raft

formation).
1000 - 1800 (7.5%)
Controlled release.
400 (1%)
Manucol LKX
Sodium
60-170 (1%)
Kelcosol
Sodium
1000-1500 (1%)
Manugel LBA
Sodium
500 (10%)
Manucol LB
Sodium
4 (1%)
Kelcoloid S
Propylene Glycol
Manucol DH
Sodium
Gelling.
Viscosity enhancer.
25 (1%)
40-90 (5%)
Manucol DMF Sodium
300 (1%)
Kelvis *
760 (1%)
Sodium
natural disintegrant in wet and

direct compression granulation.
Thickener and stabilizer for

syrups, emulsions.
Protanal Ester Propylene Glycol

SD-LB
Kelcoloid
K3B426
700 - 1800 (2%)
Propylene Glycol
120 (1%)
Kelcoloid HVF Propylene Glycol

*
400 (1%)
Kelcoloid LVF
*
Propylene Glycol
120 (1%)
Manucol
Ester E/RK *
Propylene Glycol
125 (1%)
Manucol
Ester M *
Propylene Glycol
200 (1%)
Protanal KF
200 *
Potassium
200 400 (1%)
Protanal TA
250 *
Triethanolamine
200 400 (1%)
Kelmar *
Potassium
400 (1%)
Manucol SS /
LL
Sodium
200 (1%)
Kelset
Sodium-Calcium
Keltose *
AmmoniumCalcium
Semi-gel (1%)
Protanal LF
200 M
Sodium
200 400 (1%)
Protanal LF
10/60
Sodium
20 - 70 (1%)
Manucol LF
Sodium
25 (1%)
* Non-pharmacopeial grades
500 1000 (0.5%)
Dental Impression
materials.
Dental Fixtures.
Selfgelling polymers for

controlled release.
Wound Healing.
KLEPTOSE
Betadex USP/NF, EP, JPE
The complexes formed with betacyclodextrin are of monomolecular type leading to

the concept of molecular encapsulation. Betacyclodextrins can improve the
solubility of poorly soluble compounds and finds use as encapsulating agents,
solubility and stability enhancers for tablets, capsules, sachets and oral
suspensions. They are also used for taste masking of bitter or unpleasant active
ingredients.
Grade
Description
Application
Kleptose STD
Standard grade
For inclusion in liquid phase.
Kleptose DC
Granular grade
For direct compression.
Kleptose 10
Micronized grade
For aerosols.
Kleptose 7PC
Low moisture grade
For inclusion in dry phase.
KLEPTOSE HPB / HP
Hydroxypropyl Betadex (HPBCD) USP/NF, EP, JPE
Hydroxypropyl Betadex (HPBCD) are purified polydisperse products resulting from

controlled reaction of propylene oxide and native betadex under base catalysis. By
virtue of its amorphous polydisperse composition, it overcomes the low solubility
and inadequate biological tolerance of the native betacyclodextrin. Kleptose HPB is
produced in a purpose built, state-of-the-art manufacturing plant following USFDA
type GMP quality guidelines for API and is perhaps the only brand supported by
toxicology data.
Grade
Description
Application
Kleptose HPB
HPBCD with medium

molar substitution
(Endotoxin controlled)
Kleptose HP
HPBCD with high

molar substitution
(Oral grade)
Increases water solubility of poorly soluble

drugs by encapsulation. Suitable for
parenteral solutions, syrups, oral suspensions
and dry formulation. Increases bioavailability
and improves organoleptic properties of
bitter and unpleasant actives.
KLUCEL
Hydroxypropyl Cellulose USP/NF, EP, JP
KLUCEL HPC is non-ionic water-soluble cellulose ether, formed by reaction of

cellulose with propylene oxide. KLUCEL provides a remarkable set of physical
properties for tablet binding, modified release and film coating. It combines organic
solvent or aqueous solubility, thermoplasticity and surface activity with aqueous
thickening and stabilizing properties.
Grade
Viscosity in mPas
(% w/w)*
Application
Klucel LF
Pharm
75 - 150 (5%)
Tablet binding for immediate release - Yields

unmatched tablet hardness and friability in wet
granulation and direct compression or dry
granulation.
Klucel LXF
Pharm
(extra fine)
Klucel GF
Pharm
Modified release - Provides effective diffusion

limiting matrix systems.
150 - 400 (2%)
Tablet coating - Imparts good flexibility and

adhesion to films while providing a good barrier to
water and oxygen transmission.
Klucel GXF
Pharm
(extra fine)
Klucel JF
Pharm
150 - 400 (5%)
Klucel JXF
Pharm
(extra fine)
Klucel EF
Pharm
300 - 600 (10%)
Klucel EXF
Pharm
(extra fine)
Klucel HF
Pharm
1500 - 3000 (1%)
Klucel HXF
Pharm
(extra Fine)
Klucel MF
Pharm
4000 - 6500 (2%)
Klucel MXF
Pharm
(extra fine)
*Viscosity in milli Pascal per second (mPas or cps) determined on aqueous solutions as per indicated weight %. at 250 C + 0.50 C using a
Brookfield - Syncro-Lectric LVF viscometer.
KOLLICOAT IR
PVA-PEG graft copolymer
A breakthrough in instant release film coating, Kollicoat IR is an innovative new

coating polymer derived from BASFs extensive polymer research. They are
basically polyvinyl alcohol-polyethylene glycol graft copolymers slightly modified to
render different application values. All the grades are in powder form and give an
extremely flexible film without addition of any plasticizer and offer pH independent
release. Kollicoat IR grades are white to faintly yellow free-flowing powder that is
very rapidly soluble in acidic, neutral and alkaline aqueous media. Such aqueous
solutions have low viscosity.
Grade
Description
Application
Kollicoat IR
Graft copolymer of
75% polyvinyl alcohol
units and 25%
polyethylene glycol
units
Used for instant release coating of tablets, pellets

and particulate matter, as a pore former in sustainedrelease coatings, as a binder using a binding solution
for wet granulation.
Kollicoat IR
White
Graft copolymer of
75% polyvinyl
alcohol units and
25% polyethylene
glycol units with
white pigments
Ready-to-use, white colour coating system.

Instantaneous dispersion due to a patented
manufacturing process.
Kollicoat
Protect
Co-processed
product of Kollicoat
IR and Polyvinyl
alcohol
Ready-to-use moisture barrier system for use

in combination with pigments.
KOLLICOAT MAE
Methacrylic acid / Ethyl acrylate copolymer USP/NF, EP, JPE
Kollicoat MAE 30 DP and Kollicoat MAE 100P are anionic polymers based on
methacrylic acid and methacrylic acid esters and are used as film-formers for the
production of enteric coatings for solid dosage forms. The ratio of carboxyl groups to
ester units is about 1:1. The films are insoluble below pH 5 and thus resistant to
gastric fluid. By salt formation in the neutral to weakly alkaline medium of intestinal
fluid, the films dissolve step-wise at pH values above 5.5.
Grade
Description
Kollicoat MAE Aqueous, milky white,

30 DP
low viscosity
dispersion with solid
Application
For enteric film coating of tablets, pellets, capsules,

crystals, soft gelatin capsules and other solid dosage
forms. . Also used as a moisture barrier, taste odour
Kollicoat MAE
100 P
content of 30% and a

faint characteristic
odour
masking and as a barrier between incompatible

actives.
White, partially
neutralized,
redispersible
powder with a faint
characteristic odour
For the production of an aqueous dispersion

for coating or a solution in organic solvents
for enteric coatings on tablets, pellets,
capsules, crystals, soft gelatin capsules and
other solid dosage forms.
KOLLICOAT SR 30 D
Polyvinyl acetate dispersion EP
Kollicoat SR 30 D is a an aqueous dispersion consisting of 27% polyvinyl acetate

stabilized with 2.7% povidone and 0.3% sodum lauryl sulfate. This dispersion is
suitable for the manufacture of pH independent sustained release formulations.
Very effective control of drug release is achieved by coating pellets, granules and
crystals. This dispersion can also be used for taste masking.
Grade
Description
Application
Kollicoat SR
30 D
Low viscosity, milky

white or slightly
yellowish dispersion
with solid content of
30% and a weak
characteristic odour
Used for sustained release coating of pellets,

granules, etc; for sustained release matrix tablets; for
taste and odour masking and protective coatings of
interacting ingredients.
KOLLIDON
Povidone USP/NF, EP, JP
The Kollidon range consists of soluble polyvinyl pyrrolidone which is obtained by

radical polymerization of N-vinylpyrrolidone in water or isopropanol under cGMP
conditions to yield the chain structure constituting polyvinylpyrrolidone (PVP). By
virtue of its solubility in water and many organic solvents, its high binding power
and ability to form complexes, soluble PVP occupies a special position among the
synthetic colloids.
Kollidon is available in different grades on the basis of their K-value and molecular
weight. All grades are supplied as almost white, free flowing, tasteless powders with
a slight characteristic odour in pharmaceutically pure form.
Description
Grade
Kvalue
Kollidon 12 PF 10.2 - 13.8
Molecular
weight (Mw)
Application
Low (2000-3000) Pyrogen free grade, used as
solubilizing, stabilizing agents,

dispersants and crystallization
inhibitors particularly for injectables;
especially antibiotics in solution or
lyophylisate form.
Kollidon 17
PF
15.3 - 18.0
Low (700011000)
Kollidon 25
22.5 - 27.0
Kollidon 30
27.0 - 32.4
Medium (28000 - Versatile and widely used as

34000)
binders in tablets, capsules and
granules, stabilizers in oral
Medium (44000 - suspensions, film formers,
dispersants for pigments,
54000)
thickeners and bioavailability
enhancers
Kollidon 90 F
81.0 - 96.3
High (1000000 1500000)
Same as Kollidon 12 PF. Can be

additionally used as solubilizer,
film former or thickener in
ophthalmic preparations.
Highly effective binder for wet

and dry granulation; stabilizer
and thickener for oral and
topical solutions including
ophthalmic preparations.
KOLLIDON CL
Crospovidone USP/NF, EP, JPE
Crospovidone grades are the insoluble grades of Povidone manufactured by a

polymerization process that yields crosslinked insoluble polyvinylpyrrolidone in the
form of a popcorn polymer. The polymerisation is performed using an aqueous
system.
Crospovidones are Super Disintegrants completely insoluble in solvents. In
contrast to many other disintegrants they are also non-water soluble. As a
consequence, there is no influence on the disintegration of a tablet and the
dissolution of the active due to the increased viscosity. The crosspovidones act as
disintegrants by absorbing water and subsequently swelling. This gain in volume is
responsible for the subsequent disintegration of the tablet. The different Kollidon CL
are distinguished by their different particle sizes.
Grade
Description
Application
Kollidon CL
Standard grade
Used as a tablet disintegrant and for improving the

release of active substances from tablets, capsules
and granules.
Kollidon CL-F
Fine particle size

grade
Used as disintegrant in tablets, especially in

formulations for small tablets and in wet
granulation (less content uniformity
problems).
Kollidon CLSF
Superfine particle
size grade
Used as disintegrant in fast dispersible

tablets for a smooth mouth-feel.
Kollidon CL-M
Micronized grade
Used as a stabilizer for oral and topical

suspensions and for improving the release of
active substances from tablets, capsules and
granules.
KOLLIDON SR
Blend of Polyvinyl Acetate and Povidone
Kollidon SR is a blend of polyvinyl acetate and povidone for use as a matrix-forming

agent in directly compressible sustained release tablets. It consists of 80%
polyvinyl acetate and 19% povidone alongwith small quantities of sodium lauryl
sulfate and silica as stabilizers.
Polyvinyl acetate is a very plastic material that produces a coherent matrix under
low compression forces. When the tablets formulated using Kollidon SR are
introduced into gastric or intestinal fluid, the water soluble povidone is leached out
to form pores through which the active ingredient slowly diffuses out through these
pores to give sustained action. Kollidon SR contains no ionic groups and is therefore
inert to drug substances. The sustained-release properties are unaffected by ions or
salts.
Grade
Kollidon SR
Description
Kvalue
Characteristics
60.0 - 65.0
White or slightly
yellowish, freeflowing powder,
insoluble in water
(only povidone
part is soluble)
and very soluble
in NMP
KOLLIDON VA 64
Copovidone USP/NF, EP, JPE
Application
Used in formulation of pH
independent sustained release
matrix dosage forms tablets,
pellets and granules by either
direct compression, roller
compaction, wet granulation or
extrusion.
Kollidon VA 64 grades are excellent dry binders. Basically they are vinylpyrrolidone
- vinyl acetate copolymers which are soluble in both water and alcohols. It is white
or slightly yellowish powder with a faint characteristic odour and practically no
taste. An important property of Kollidon VA 64 is its plasticity which distinguishes
it from Povidone (eg. Kollidon). This property often gives granules and mixtures that
are less susceptible to capping during tabletting and results in tablets that are less
brittle.
Grade
Description
Kvalue
Kollidon VA 64 25.2 - 30.8
Kollidon VA
64 Fine
Application
Characteristics
Copolymer of
vinylpyrrolidone
and vinyl acetate
in a ratio of 6:4 by
mass
Dry binder for direct

compression and roller
compaction; as a binder for wet
granulation in tablets, capsules
and granules; as a film forming
agent in tablet coating / subcoating and in topical sprays.
Fine particle size grade for
increased tablet hardness
resulting in less friability and
better mechanical stability.
KRONOS 1171
Titanium Dioxide USP/NF, EP, JP
KRONOS 1171 Titanium dioxide is an amorphous, fine, superwhite powder produced

by the sulphate process. It is a special anatase grade of exceptionally high purity
specifically manufactured for the pharmaceutical industry. Due to its high refractive
index, Kronos 1171 Titanium Dioxide has unique light scattering properties and thus
widely used as a white pigment and opacifier.
Kronos 1171 Titanium Dioxide complies to the latest monographs of USP/NF, EP, JP
etc as well as to several purity regulations of the EU and USFDA.
Grade
Description
Application
Kronos 1171
Anatase grade, super

Used as a white pigment and opacifier in film
white, fine particle size coating mixes for tablets, gelatin capsules, sugar
and bacteria controlled coated tablets, films and dermatological
preparations. Can also be admixed with other
pigments to lend different colour tones to tablets and
coatings.
LACTOCHEM
Lactose Monohydrate USP/NF, EP, JP
Lactochem is a white, crystalline powder. It is the alpha-isomer of lactose and in

crystalline form it is present as alpha monohydrate lactose. The water of
crystallization is tightly bound and shows no chemical activity while bound. Moisture
sorption is extremely low even at high relative humidity. Lactochem is available in
sieved and milled forms of different particle size distributions, ranging from coarse
to very fine material.
Milled Lactochem products are all characterized by small particles and high
specific surface area, resulting in good binding properties. Therefore these products
are especially useful in wet granulation tabletting, pelletization as well as
spheronization.
Grade
Description
Application
Lactochem Powder
Milled Lactose
Widely used as fillers in wet granulation processes.

Also used for capsule filling and in powder mixtures
filled into sachets.
Lactochem Coarse
Powder
Lactochem Regular
Powder
Lactochem Fine
Powder
Lactochem Extra
Fine Powder
Lactochem Super
Fine Powder
Sieved Lactochem products are all characterized by a low Carrs index, implying
good flowability and are therefore ideal for filling of capsules and sachets where
excellent flowability is needed. These products are also successfully applied as
diluents for direct compression. The finer crystal types are suitable for pelletization
as well.
Grade
Description
Application
Lactochem Crystals
Sieved Lactose
Prevents segregation in capsule based formulations

and sachets. Used as filler - binder in directly
compressible formulations.
Lactochem Coarse
Crystals
Lactochem Fine
Crystals
Lactochem Extra
Fine Crystals
LACTOPRESS
Directly Compressible Lactose USP/NF, EP, JP
Lactopress is a white, free flowing directly compressible Lactose powder. It is

available in two forms; spray dried and anhydrous with different particle sizes
distributions. The good flowability of these powders in combination with excellent
compactibility characteristics make them ideal for direct compression tabletting.
These products are also suitable for applications that require only excellent
flowability.
Lactopress Anhydrous is characterized by superior dissolution and excellent
binding properties. It consists mainly of the beta-isomer of lactose, which contains

no water of crystallization and the free moisture content is low. Lactopress
anhydrous does not absorb water even at high relative humidity which makes it the
best choice for use in direct compression of moisture sensitive actives.
Grade
Description
Application
Lactopress Anhydrous Roller dried DC As low moisture DC binder and filler in tablets and
250
Lactose, Coarse capsules. Improves stability of
particle size
moisture sensitive actives as well as their dissolution
due to its high intrinsic solubility.
Lactopress
Anhydrous Fine
Powder
Roller dried
DC Lactose,
Fine particle
size
Lactopress spray-dried is produced by spray-drying a suspension of small

crystals of lactose monohydrate. It consists mainly of spherical particles resulting in
excellent flowability and binding. Lactopress spray-dried contains up to 15%
amorphous lactose, which ensures low friction with the die wall, preventing capping
behavior. It is therefore highly effective in modern, high-speed tabletting machines.
Grade
Description
Application
Lactopress
Spray Dried
250
DC Lactose, Fine
particle size
As binder, fillerbinder, and flow aid in direct

compression due to its excellent flow and high
compressibility. Ensures good content uniformity.
Lactopress
Spray Dried
260
DC Lactose, Coarse
particle size
Lactopress
Spray Dried
DC Lactose, Coarse
particle size
LACTOPRESS GRANULATED
Lactose monohydrate, modified USP/NF, EP, JP
Lactopress granulated is a highly stable excipient having excellent flow, low density,
low hygroscopicity and good compaction properties. It has low lubricant sensitivity
and offers short disintegration time on use in formulations. The short disintegration
time together with the sweet taste, makes it and ideal excipient for use in
orodispersible tablets.
Grade
Description
Lactochem Granulated Granulated

Lactose
monohydrate
Application
Direct compression formulations

Orodispersible tablets
Low dose applications
Capsules and sachets filling
LACTOPRESS

flowability.
Grade
Description
Application
250
particle size
moisture sensitive actives as well as their dissolution
due to its high intrinsic solubility.
Lactopress
Roller dried
Anhydrous Fine
Powder
DC Lactose,
Fine particle
size

Grade
Description
Application
Lactopress
Spray Dried
250
DC Lactose, Fine
particle size

Lactopress
Spray Dried
260
DC Lactose, Coarse
particle size
Lactopress
Spray Dried
DC Lactose, Coarse
particle size
LACTOPRESS GRANULATED
Lactose monohydrate, modified USP/NF, EP, JP
Lactopress granulated is a highly stable excipient having excellent flow, low density,
low hygroscopicity and good compaction properties. It has low lubricant sensitivity
and offers short disintegration time on use in formulations. The short disintegration
time together with the sweet taste, makes it and ideal excipient for use in
orodispersible tablets.
Grade
Description
Lactochem Granulated Granulated

Lactose
Application
Direct compression formulations

Orodispersible tablets
monohydrate
Low dose applications

Capsules and sachets filling
LACTOPRESS

flowability.
Grade
Description
Application
250
particle size
moisture sensitive actives as well as their
dissolution due to its high intrinsic solubility.
Lactopress
Anhydrous Fine
Powder
Roller dried
DC Lactose,
Fine particle
size

Grade
Description
Application
Lactopress
Spray Dried
250
DC Lactose, Fine
particle size

Lactopress
Spray Dried
260
DC Lactose, Coarse
particle size
Lactopress
Spray Dried
DC Lactose, Coarse
particle size
L-HPC
Low substituted Hydroxypropyl Cellulose USP/NF, JP
L-HPC is a low-substituted hydroxypropyl ether of cellulose. It is non-ionic and less

reactive to active ingredients. It is insoluble in water and alcohols but swells in
water. It causes changes in the binding and disintegrating characteristics as a result
of subtle changes in its physical properties like particle size and substituent content.
Hence, it is widely used as a dual-functional excipient (disintegrant / binder) for
tablets, granules or other pharmaceutical solid dosage forms.
Description
Grade
Mean particle
size (m)
Particle type
Application
LHPC LH11
50
Highly fibrous
Direct Compression
(anticapping).
LHPC LH-21
40
Moderately fibrous
Regular grade (dry mixing,

wet granulation).
LHPC LH-22
40
Moderately fibrous
Lower hydroxypropoxy
content (sometimes better
disintegration).
LHPC LH-31
20
LHPC LH-32
20
LHPC LH-B1
50
Micronized
Micronized grade (Pellet

extrusion, layering).
Micronized grade with lower
hydroxypropoxy content
(Pellet extrusion, layering).
Non fibrous
High density grade suitable

for direct compression with
good flowability and high
loading capability.
* Laser diffraction method
LUDIFLASH
Compound of Mannitol, Crospovidone and Polyvinyl Acetate
Ludiflash is an innovative, unique co-processed blend of mannitol (95%),

crospovidone (5%) and polyvinyl acetate (5%) manufactured in a validated patented
process. Ludiflash is practically in a league of its own when it comes to excipients
for direct compression tablets that rapidly disintegrate in the mouth to form a
smooth and creamy texture.
Thanks to its unique composition, Ludiflash produces tablets with an excellent
compression / hardness curve, very low friability and very high content uniformity
even at high tabletting speed. The oro-dispersible tablets made with Ludiflash can
be taken without water, anytime, anywhere and have extremely rapid disintegration
(within seconds) and fast release rates.
Grade
Description
Application
Ludiflash
All-in-one system with Excellent excipient for direct compression of fasta mild sweet taste and disintegrating solid oral dosage forms (mouth-melts)
cooling effect in the
for rapid release.
mouth. White to offwhite powder with
superior flowability
and low
hygroscopicity. Does
not dissolve completely
in water or organic
solvents
LUDIPRESS
Compoud of Lactose Monohydrate and Povidone
Ludipress is the result of an intensive research and development effort by BASF to

produce an advanced excipient for the manufacture of tablets by the direct
compression process. Ludipress is white, free-flowing, tasteless and odourless
granules of lactose monohydrate (93%), povidone (3.5%) and crospovidone (3.5%)
and combines the three functionalities of a filler, binder and disintegrant into a
single, ready-to-use excipient for direct compression. The versatility of Ludipress
allows very simple formulations resulting in rapidly disintegrating tablets of
excellent hardness and low friability
Ludipress LCE, on the other hand, is a directly compressible compound of lactose
monohydrate (96.5%) and povidone (3.5%). Due to the absence of a disintegrant,
Ludipress LCE is completely soluble in water and particularly suitable for cost
saving production of lozenges, chewables, effervescent tablets etc.
Grade
Description
Ludipress
Granules of lactose
Direct compression tabletting (disintegrating tablets)
monohydrate, povidone and as a filler in hard gelatin capsules.
and crospovidone
Ludipress LCE Granular compound

of lactose
monohydrate and
povidone
LUSTRECLEAR LC - 103
Application
Directly compressible production of lozenges,

sublingual, chewable tablets particularly, in
effervescent tablets. Also used as a bulking
agent for modified release formulations.
Microcrystalline Cellulose and Carrageenan based film coating system
LustreClear LC-103 is a highly effective, proprietary all-in-one aqueous film coating

system. This unique film coating technology combines microcrystalline cellulose
(MCC) and carrageenan to provide a distinctive, smooth, satin finish on solid dosage
forms. It is clearly an innovative, cost-effective, aesthetic coating system opening
new possibilities in aqueous film coating for a wide variety of tablets and other solid
dosage forms. This advanced technology platform, makes processing easier and
offers distinctive sensory attributes. Its added advantages of taste masking and
ease of swallowing of the coated dosage forms add to the patients appeal and
compliance.
Grade
Description
Application
LustreClear
LC-103
All-in-one, aqueous,
Used for film coating of tablets and other solid
clear, conventional
dosage forms into elegant, easy to swallow and taste
film coating system
masked products.
comprising of
microcrystalline
cellulose, carrageenan
and polyethylene glycol
LUTROL E
Polyethylene Glycol (Macrogol) USP/NF, EP
Lutrol E types are liquid polyethylene glycols manufactured by alkali-catalysed

polymerisation of ethylene oxide with subsequent neutralisation of the catalyst.
Lutrol E grades are readily soluble in water, ethanol, acetone, glycols and
chloroform. The number in the name of the product is indicative of the average
molecular weight. The higher the molecular weight of the product; the less
hygroscopic it is and lower its solubility in water.
Lutrol E 300 and Lutrol E 400 are colourless, almost odourless and tasteless liquids
at room temperature; while Lutrol E 600 can be either liquid or pasty at room
temperature.
Grade
Description
Application
Lutrol E 300
Molecular weight : 285 - 315

Viscosity : 5.4 - 6.4 mPa.s
Lutrol E 400

Viscosity : 6.8 - 8.0 mPa.s
Lutrol E 600

Viscosity : 9.9 11.3 mPa.s
Used as solvents and

solubilizing agents for oral,
parenteral, topical, ophthalmic
and rectal preparations.
Carriers for dissolved or
suspended drug in soft gelatin
capsules. Widely used as an
ointment base.
LUTROL F
Poloxamer USP/NF, EP, JPE
The Lutrol F grades or Poloxamers are block copolymer of polyoxyethylene

polyoxypropylene (Pluronics). While Lutrol F 68 (Poloxamer 188) is a white to
slightly yellowish, waxy substance in the form of microbeads with a faint odour,
Lutrol F 127 (Poloxamer 407) is a white, coarse-grained powder with a waxy
consistency. Both grades are soluble in ethanol and water.
The Ltrol micro grades - Ltrol F micro 68 and Ltrol F micro 127 are white,
micronized Poloxamer powders of average particle size of ~50 m. with a weak
odour.
Grade
Description
Application
Lutrol F 68
Poloxamer 188 (Block

polymer of 81%
polyethylene glycol
and 19%
polypropylene glycol)
with an average
molecular weight of
8600
Emulsifier, solubilizer and suspension stabilizer in

liquid, oral, topical and parenteral dosage forms, as
a plasticizer and bioavailability enhancer in solid
preparations. Also as coemulsifier in creams and
emulsions and as a tablet lubricant.
Ltrol Micro
Micronized
Dissolution enhancer for actives in solid oral
68
Poloxamer 188 with dosage forms; water soluble lubricant for

a mean particle size effervescent tablets and for actives
of 50 m for
incompatible with stearates.
homogenous mixing
Lutrol F 127
Poloxamer 407
(Block polymer of
73% polyethylene
glycol and 27%
polypropylene
glycol with an
average molecular
weight of 12,000
Gel former, thickening agent and solubilizer

in oral and topical solutions and as a
stabilizer in topical suspensions.
Ltrol Micro
127
Micronized
Poloxamer 407 with
a mean particle size
of 50 m for
homogenous mixing
Dissolution enhancer for actives in solid oral

dosage forms; water soluble lubricant for
effervescent tablets and for actives
incompatible with stearates.
MAGNABRITE
Magnesium Aluminum Silicate USP/NF, BP

Magnabrite product range are highly refined, naturally occurring, complex colloidal white
smectite clays i.e. Magnesium Aluminum Silicates manufactured to meet the specifications of the
USP/NF and BP. Chemically Magnesium Aluminum Silicate is a blend of colloidal
montmorillonite and saponite that has been processed to remove grit and non- swellable ore
components. The plate-like structure and colloidal nature of Magnabrite contributes to a wide
range of applications for stabilization of emulsions, as a suspending agent, thickener, rheology
modifier, binder, and as a tablet disintegrant. Magnabrite is available in different particle sizes
and varying viscosity to suit the end-user.
Grade
Description
Type
Application
Viscosity at 5%
solids (cPs)
800 - 2200
Magnabrite HV High viscosity

grade, Small
flakes,
Excellent suspension and emulsification

properties, delivers high viscosity with
excellent rheology in low solid
formulations.
Magnabrite K
Acid stable
grade, Small
flakes,
100 - 300
Low acid demand and high acid

compatibility, used to reduce thickening
and flocculation in acidic preparations /
suspensions.
Magnabrite S
Standard
grade, Small
flakes,
225 - 600
Excellent emulsification and thickening

abilities, used in formulations requiring
medium viscosity, high brightness and
ease of dispersion.
Magnabrite F
Micro fine
150 - 450
powder grade,
Free flowing
Used as an inert low-bulk disintegrant in

large tablets. Also used as a suspending
agent.
MAGNABRITE HS
Purified Bentonite USP/NF, BP
Magnabrite HS is an absorbent aluminium phyllosilicate, highly refined, naturally occurring

complex colloidal white smectite clay. Chemically it is colloidal montmorillonite which has been
processed to remove grit and non-swellable ores. The properties of Magnabrite HS are similar to
that of the other Magnabrite grades.
Grade
Description
Type
Viscosity at 5%
Application
solids (cPs)
40 - 200
Magnabrite HS High
electrolyte
stability grade,
Small flakes
Easily hydrates in hot or cold water, used

as suspending, thickening agent and
binder.
MAGNESIUM CARBONATE USP/NF, EP, BP
Magnesium carbonate is a basic hydrated magnesium carbonate or a normal hydrated magnesium

carbonate. DSPs magnesium carbonates are manufactured by an unique process which ensures
freedom from the impurities generated by the commonly used precipitation processes grades.
Their product is thus of exceptionally high purity and characterized by particularly low levels of
impurities such as lead and other minerals.
They are offered in two grades Basic and Heavy.
Grade
Description
Application
Basic
Magnesium
Carbonate
Light grade
For use in the manufacture of antacid preparations
(Tapped BD: 0.35-0.55 and mineral supplements, Also used in microsphere
g/cc)
formulations for the purpose of stabilizing
encapsulated proteins or to absorb flavors, in
tableting processes.
Heavy
Magnesium
Carbonate
Heavy grade
(Tapped BD : NLT
0.50 g/cc)
To produce tablets with high crushing strength, low

friability, and good disintegration properties.
MAGNESIUM CARBONATE LIGHT USP/NF, EP, BP
Magnesium carbonate is a basic hydrated magnesium carbonate or a normal hydrated magnesium

carbonate. Scoras magnesium carbonate is manufactured by the Pattinson process which
ensures freedom from the impurities generated by the commonly used precipitation processes
grades. The product is thus of high purity and exceptional quality.
Grade
Description
Application
Basic
Magnesium
Carbonate
Heavy grade, free

flowing
Viscosity regulator, anti-caking and free flow aid.

Used in antacid preparations / tablets, laxatives and
in production of pharmaceutical magnesium
derivatives. Also used in mineral supplements &
food additives.
MAGNESIUM HYDROXIDE USP/NF, EP, BP
Magnesium hydroxide is an inorganic compound, not very soluble in water. While the solubility
of magnesium hydroxide is low, all of the magnesium hydroxide that does dissolve in the water
does dissociate. DSPs magnesium hydroxides are manufactured by an unique process which
grades. Their product is thus of exceptionally high purity and characterized by particularly low
levels of impurities such as lead and other minerals. They are available as spray dried powders
with different bulk densities thus offering a wide choice of compounding possibilities for tablet
and powder dosage systems.
Grade
Description
Application
Magnesium
Hydroxide
HD5
Lowest bulk density

grade
Spray dried, directly compressible powders for use

in the manufacture of antacid preparations and
mineral supplements.
Magnesium
Hydroxide
HD7
Low bulk density grade
Magnesium
Hydroxide
HD9
Medium bulk density

grade
Magnesium
Hydroxide
HD12
High bulk density

grade
MAGNESIUM OXIDE USP/NF, EP, BP
Magnesium oxide is a free flowing white powder, insoluble in alcohol and almost insoluble in
water. It is a source of magnesium and formed by an ionic bond between one magnesium and one
oxygen atom. DSPs magnesium oxides are manufactured by an unique process which ensures
freedom from the impurities generated by the commonly used precipitation processes grades.
Their product is thus of exceptionally high purity and characterized by particularly low levels of
impurities such as lead and other minerals. They are available in a variety of grades to meet the
requirements of the formulator.
Grade
Description
Magnesium
Oxide Light
Low bulk density grade For use in the manufacture of tablet-form antacid
preparations, pH modifier, mineral supplements and
in the production of pharmaceutical grade
magnesium derivatives.
Heavy grade
Magnesium
Oxide PHRA
50
Magnesium
Oxide DC
Application
grade, Granular
MAGNESIUM OXIDE LIGHT USP/NF, EP, BP
Magnesium oxide is a free flowing white powder, insoluble in alcohol and almost insoluble in
water. It is a source of magnesium and formed by an ionic bond between one magnesium and
one oxygen atom. Scoras magnesium oxides are manufactured by the Pattinson process which
grades. The product is thus of high purity and exceptional quality.
Grade
Description
Magnesium
Oxide Light
Low bulk density grade Used as precursor of magnesium hydroxide, pH

modifier and viscosity regulator in antacid
preparations. Also used in mineral supplements,
food additives and in production of pharmaceutical
grade magnesium stearates.
MALIC ACID
Application
D, L Malic Acid USP/NF, EP
Malic Acid is widely found in nature and is the predominant organic acid in many fruits and
berries. Commercially, Malic Acid is manufactured by hydration of Maleic Anhydride, at high
temperature and pressure. The Malic Acid crystallizes out from aqueous solutions as white,
translucent, anhydrous, non-hygroscopic and non-volatile crystals. It's properties allow it to be
stored under normal conditions for a very long time without any caking & contribute to its long
shelf life.
Malic Acid works by blending with flavours and essences. Its acid taste building up slowly at
the beginning, but persists for a long period. The final effect gives a stronger taste and a
pronounced flavor note. It works synergistically with most sweetners and has the ability to
enhance the effect of the aromas used to mask the undesirable tastes and smell of medicinals.
Polynt offers malic acid in both powder & granule forms.
Grade
Description
Malic acid
granular
White crystalline
powder or granules
with a distinct acidic
taste. Extremely
Malic acid fine
soluble in water
granular
Application
Used in throat lozenges, cough syrups, effervescent
powders and tablets. Masks undesired taste and
odour of medicinals. Also used in health / sports
drinks and anti-wrinkle creams.
Malic acid
special fine
granular
Malic acid
powder
MALTISORB & LYCASIN
Maltitol USP/NF, EP
Maltitol is a white crystalline powder of high purity obtained by the catalytical hydrogenation of
D-maltose using a process patented by Roquette. It is a dimeric polyol with a cool mouthfeel and
sweetness close to that of Sucrose. Maltitol is a stable polyhydric non-cariogenic sugar alcohol
with low glycemic index and low calorific value.
Maltilol solution is obtained by the hydrogenation of maltose syrup and is constituted by D-
sorbitol, hydrogenated disaccharides and polysaccharides. It is supplied as a pure, odourless

liquid with a pleasant sweet taste. Roquette offers Maltitol solution in different compositions to
generate very little acid production when in contact with the plague bacteria; which means they
are guaranteed not to induce caries. It has high sweetening power with good solubility and is
used to totally replace sugar in syrups, lozenges and jellies for specific patient groups.
Grade
Maltisorb P 90
Description
Fine particle size
Maltisorb P 200 Coarse particle size
Application
Diluent for tablets and sachets, excipient for coating
as well as for candying of lozenges, sweetener for
pharmaceutical chewing gums. Used for chewable,
suckable and effervescent tablets.
Maltisorb 75/75 Dry maltitol syrup

(72% - 76%)
Bulk sweetener for pastilles and lozenges.
Lycasin 80/55
Dry maltitol syrup

(50% - 55%)
Liquid sweetener for sugarless syrups, suspensions,

lozenges, oral ampoules, and pharmaceutical
chewing gums.
Lycasin HBC
Dry maltitol syrup

Sweetener for hard boiled candies, pastilles and
(50% - 55%) with high lozenges.
viscosity
GUM BASE
Non-nutritive masticatory substance
Gum base, especially the medicated chewing gum represents the novel and alternative drug
delivery system. It is an inert, insoluble, non-nutritive product designed to deliver flavours,
minerals, vitamins, sweetners and active pharmaceutical ingredients. Once formulated, it is
designed to release the active on chewing without having to swallow or consume the base. The
product can be administered anywhere, anytime and does not require a liquid medium to
swallow or consume the base.
Unique formulations have been designed with gum base for smoking reduction, weight
management, heartburn relief, dry mouth relief, stress reduction, memory and concentration
improvement etc. Various formulations for nicotine delivery, motion sickness and pain relief are
already commercialized. While MedGumBase is ideal for formulating medicated chewing
gums, the Compressed Powder Gum (CPG) forms the basis for a new delivery vehicle for
functional products, with an exceptional chew. CPG, made by a unique process, can be
compressed using cold and dry processes on tablet presses and is ideal for sensitive actives.
CPG offers greater flexibility over conventional chewing gum technology in terms of shape, size
and flavours.
Grade
Description
Application
MedGumBase Specific gum base

developed for
medicated chewing
gums
CPG
(Compressed
Powder Gum)
Absorption through oral mucosa, Good distribution

of active principles, Bypasses hepatic first pass, No
degradation of actives, Easy and pleasant
administration for better patient compliance and
emergency dosage, Efficient delivery of large doses.
chewing gum base
powder for sensitive
actives
* Available with & without flavours. Conventional chewing gum base and Bubble gum base can also be provided on demand
METOLOSE
Hypromellose (HPMC) USP/NF, EP, JP

Methylcellulose (MC) USP/NF, EP, JP
Metolose is a non-ionic water-soluble cellulose ether derived from highly purified natural pulp
by an initial treatment with caustic soda to obtain alkali-cellulose, followed by etherification
with methyl chloride or with the combination of methyl chloride and propylene oxide. Metolose
consists of Methylcellulose and three substitution types of Hypromellose (Hydroxypropyl
methylcellulose) each available in several grades differing in viscosity.
Metolose can be used as a binder for solid dosage forms such as tablets and granules. It also
provides a variety of functions such as water retention, thickening, protective colloid, surface
activity, sustained release, film formation etc. Shin-Etsu also manufactures specific Metolose SR
grades for use in hydrophilic sustained release matrix systems.
Description
Grade
Viscosity (cPs)
USP Substitution
Type
Application
2910
Metolose 60SH-50
50
Metolose 60SH-4000
4000
2910
Metolose 60SH-10000
10000
2910
As sustained release agent,

thickener, suspending agent
and binder for tablets and
granules. Also used for
Metolose 65SH-50
50
2906
Metolose 65SH-4000
4000
2906
Metolose 90SH-4000
4000
2208
Metolose 90SH-15000
15000
2208
Metolose 90SH100000
100000
2208
Metolose 90SH100SR
100
2208
Metolose 90SH4000SR
4000
2208
Metolose 90SH15000SR
15000
2208
100000
2208
Metolose SM-4
Low viscosity
Methylcellulose for granule
coating.
Metolose SM-15
15
Metolose SM-400
400
Metolose SM-4000
4000
Methylcellulose for use as

granulating agent,
emulsifying agent, thickener
and bulk laxative.
ophthalmic formulations.
In hydrophilic sustained
release matrix systems and
direct compression
applications. Gives more
controllable and reproducible
drug release alongwith good
product consistency.
METOLOSE
Hypromellose (HPMC) USP/NF, EP, JP

Methylcellulose (MC) USP/NF, EP, JP
Metolose is a non-ionic water-soluble cellulose ether derived from highly purified natural pulp
by an initial treatment with caustic soda to obtain alkali-cellulose, followed by etherification with
methyl chloride or with the combination of methyl chloride and propylene oxide. Metolose
consists of Methylcellulose and three substitution types of Hypromellose (Hydroxypropyl
methylcellulose) each available in several grades differing in viscosity.
Metolose can be used as a binder for solid dosage forms such as tablets and granules. It also
provides a variety of functions such as water retention, thickening, protective colloid, surface
activity, sustained release, film formation etc. Shin-Etsu also manufactures specific Metolose SR
grades for use in hydrophilic sustained release matrix systems.
Description
Grade
Viscosity (cPs)
USP Substitution
Type
Application
2910
Metolose 60SH-50
50
As sustained release agent,

thickener, suspending agent
and binder for tablets and
granules. Also used for
ophthalmic formulations.
Metolose 60SH-4000
4000
2910
Metolose 60SH-10000
10000
2910
50
2906
Metolose 65SH-4000
4000
2906
Metolose 90SH-4000
4000
2208
Metolose 90SH-15000
15000
2208
Metolose 90SH100000
100000
2208
Metolose 90SH100SR
100
2208
Metolose 90SH4000SR
4000
2208
15000
2208
100000
2208
Metolose SM-4
Low viscosity
Methylcellulose for granule
coating.
Metolose SM-15
15
Metolose SM-400
400
Metolose SM-4000
4000
Methylcellulose for use as

granulating agent,
emulsifying agent, thickener
and bulk laxative.
Metolose 65SH-50
\
NATROSOL
Hydroxyethyl Cellulose USP/NF, EP
In hydrophilic sustained
release matrix systems and
direct compression
applications. Gives more
controllable and reproducible
drug release alongwith good
product consistency.
NATROSOL HEC is a non-ionic water-soluble cellulose ether, formed by reaction of cellulose

with ethylene oxide. It is used as a modified release tablet matrix, film former and thickener,
stabilizer and suspending agent for oral and topical applications when a non-ionic material is
desired. NATROSOL is easily dispersed in cold or hot water to give solutions of varying
viscosities and desired properties, yet it is insoluble in organic solvents.
Grade
Viscosity in mPas (%
w/w)*
Application
Natrosol HHX
Pharm
3500 - 5500 (1%)
Modified release - Provides effective diffusion

limiting matrix systems; most suited for actives with
low water solubility.
Natrosol HX
Pharm
1500 - 2500 (1%)
Natrosol M
Pharm
4500 - 6500 (2%)
Natrosol G
Pharm
250 - 400 (2%)
Natrosol L
Pharm
75 - 150 (5%)
Tablet coating - Imparts flexibility to films while

providing a good barrier to water and oxygen
transmission.
Solutions, gels & emulsions - Controls rheology,
provides thickening and pseudoplasticity, and
stabilizes emulsions with high salt tolerance and
surfactant compatibility.
NUTRIOSE
Soluble Fibre
Nutriose are specialty dextrins developed as innovative soluble dietary fibres with valuable
technological advantages. They are made by dextrinification of wheat or corn starch followed by
refining, purification and drying. The result is an agglomerated water soluble dextrin with high
dietary fibre and very low sugar content. These free flowing micro-granulated powders have
high digestive tolerance and exhibit good stability to both pH and heat.
Nutriose offers other unique benefits like low glycaemic and insulinaemic response, quick
dissolution, high stability, quick dispersion, low osmolality, non-cariogenic, low caloric value,
neutral taste etc. These properties alongwith the simplicity of use makes Nutriose the fibre of
choice for clinical nutrition and for all nutraceutical forms.
Grade
Description
Application
Nutriose FB
Nutriose FM
Speciality dextrin from Fibres for gut regulation, moderation of glucidic and
wheat
lipid metabolism, obesity prevention etc. Also used
for low calorie formulations, direct compression /
granulated formulations and enteral nutrition.
Speciality dextrin from
maize
PC-10
Pregelatinized Starch USP/NF, EP, JPE
PC-10 is a partially pregelatinized starch grade manufactured by controlled thermal gelation of

raw corn starch. It is inert without any starch odour, high in water-absorbing and has pHindependent disintegrating properties. With a far lower soluble content; its particles swell in
contact with water rather than dissolve thereby serving as an excellent disintegrant to effect
active-ingredient release. This mechanism makes possible higher performance levels and new
application parameters for solid dosage formulations.
As compared to conventional pregelatinized starch; PC-10 has higher whiteness, better texture
and superior flow properties. With these and few of its other unique properties it is considered as
an ideal excipient for many unstable actives (API).
Grade
Particle size (m)
Application
PC-10
70
Disintegrant, granulation aid and dissolution

enhancer. Also a stabilizer for moisture-sensitive
actives and carrier for hygroscopic substances like
herbal extracts.
PEARLITOL
Mannitol USP/NF, EP, JP
Mannitol is a polyol manufactured by catalytic hydrogenation of starch, a natural raw material of

vegetable origin. It occurs as a slightly sweet, white crystalline powder that gives a cooling
sensation on dissolution in the mouth. It has excellent stability, low hygroscopicity and good
solubility in different solvents. It forms an ideal excipient for dry formulations (granules, pellets,
tablets) and as a cryoprotective agent in freeze drying applications. It is low-calorie, non-
cariogenic and ideal for sugar-free formulations. These exceptional properties and the excellent
chemical stability make Pearlitol the best choice in excipients for stable formulations.
Crystalline Mannitol
Grade
Description
Application
Pearlitol PF
Pyrogen free grade
(Mannitol PFG)
Diureticosmotic for injectable solutions.
Pearlitol 25 C
(Mannitol 25)
Extra fine particle size
Pearlitol 50 C
(Mannitol 35)
Diluent for unstable or moisture sensitive actives

and flash release, as freeze drying carrier and
sweetener with cooling effect for ODTs and
pharmaceutical chewing gums.
Pearlitol 160 C
(Mannitol 60)
Coarse particle size
Granular Mannitol
Grade
Description
Pearlitol 100
SD
Spray dried, fine

particle size
Pearlitol 200
SD
Spray dried, medium

particle size
Pearlitol 300
DC
Granulated, fine
particle size
Pearlitol 400
DC
Granulated, medium
particle size
Pearlitol 500
DC
Granulated, coarse
particle size
Application
Excellent fillerbinder for direct compression of
chewable, effervescent and fast dissolving tablets.
Ideal for formulation of unstable or moisture
sensitive actives, sugar free diluent for capsules and
sachets. Also used as neutral carrier base for loading
of actives.
PEARLITOL FLASH
Compound of Mannitol and Maize starch
Pearlitol Flash is a compound produced by granulation of 80% mannitol and 20% extra white
maize starch. The intrinsic composition of Pearlitol flash enables successful formulation of ODTs
even at low lubricant levels. The mannitol imparts the sweet and pleasant taste while the starch
aids in instant disintegration.
ODTs formulated with Pearlitol Flash melt in the mouth with a creamy, smooth texture and a
uniquely pleasing taste. Pearlitol Flash helps in the formulating robust tablets of good hardness
capable of disintegrating within stipulated time.
Grade
Description
Application
Pearlitol Flash

(200 m)
Direct compression of orodispersible tablets.
PHARMACOAT
Hypromellose USP/NF, EP, JP
Pharmacoat is low viscosity Hypromellose (Hydroxypropyl Methylcellulose) based film coating

polymer. It is easy to use, versatile and gives an excellent finish to the tablet. It is also effective
as a binder since it does not interact with drugs, has superior stability and is non-ionic in
character. It is available in various viscosity grades to suit the end user.
Description
Grade
Viscosity (cPs)
USP Substitution
Type
Application
Binder in wet granulation.
Pharmacoat
603
2910
Pharmacoat
645
4.5
2910
Pharmacoat
606
2910
Pharmacoat
615
15
2910
Film coating, greater film

strength.
Pharmacoat
904
2208
Binder for sugar coating.
Regular film coating.
PHARM-A-SPHERESTM
Sugar Spheres (Non-Pareil seeds) USP/NF, EP
Pharm-a-spheres (Sugar Spheres) are inert, neutral pellets of nearly spherical form, usually of
diameter below one millimeter. They have a slight sweet taste and are composed of sucrose and
corn starch. Sugar Spheres are modern day excipients used in capsule and tablet formulations
particularly in multiparticulate formulations. They are the core upon which a drug is coated by a
classic coating pan process or a fluidised bed coating process; usually for controlled or sustained
release applications.
Werners Pharm-a-spheres are of superior quality in terms of its greater mechanical strength,
low friability and high sphericity which allows precise calculation of drug quantity to be loaded.
Its narrow particle size distribution coupled with its superior flow characteristics and total
regulatory support makes it today the brand of choice for a majority of the pharmaceutical
formulators. Werners Pharm-a-spheres are available in a variety of particle diameters ranging
from 100 m to 2000 m.
Particle size
range
(Mesh ASTM)
Particle size range

(m)
120 140
106 125
100 120
125 150
80 100
150 180
70 80
180 212
60 70
212 250
50 60
250 300
45 50
300 355
45 60
250 355
40 60
250 425
40 50
300 425
40 45
355 425
35 55
355 500
Application
Used as drugfree cores for controlled or sustained

release systems.
35 50
300 500
35 45
400 450
35 40
425 500
30 35
500 600
25 30
600 710
20 25
710 850
18 20
850 1000
16 20
850 1180
16 18
1000 1180
14 16
1180 1400
12 16
1400 1700
12 14
1400 1700
10 12
1700 2000
* Special sizes and mixtures are also possible.
POLYSORB
Anhydrized Liquid Sorbitol USP/NF, EP
Polysorb 85/70/00 is a partially dehydrated liquid sorbitol presented as a clear, colorless, syrupy
liquid, partially miscible with water but practically insoluble in oil.
It was developed as an additive for manufacture of soft gels. Its remarkable plasticizer
properties helps to form soft gelatin capsules without surface crystallization or graining and
prevents leaching into the filler media within the soft gel. Its high dry solid content of almost
83% makes it the most efficient soft gel plasticizer.
Grade
Description
Application
Polysorb
85/70/00
Aqueous solution of
D-Sorbitol and
Sorbitans
Optimal plasticizer for gelatin shell of soft gel

capsules. Enables good stability with the filler soft
gels.
PRONOVA UP
Ultra Pure Sodium Alginates USP / NF, EP
Pronova UP sodium alginates are a family of highly purified and well-characterized alginates
with ultra low levels of endotoxins and proteins developed for use in biomedical and
pharmaceutical applications. They are available in different viscosities and C-5 epimer a-Lguluronate (G) content. These products are manufactured in a specially designed production
facility in compliance with cGMP (21 CFR 210, 211), ISO 9001:2000 and ISO 13485 standards.
The safety and toxicology profile of ultrapure PRONOVA sodium alginate are covered in a Drug
Master File on file at the US FDA.
Alginates are linear copolymers with homopolymeric blocks of (14)-linked b-D-mannuronate
(M) and its C-5 epimer a-L-guluronate (G) residues, respectively, covalently linked together in
different sequences or blocks. Alternating M and G blocks form the most flexible chains which
exhibit excellent solubility at lower pH. In contrast to most other polysaccharide gels, alginate
gels can develop and set at constant temperature lending them useful in pharma applications
involving temperature sensitive molecules.
Grade
Viscosity (mPas)
Mannuronic / Guluronic acid content
Pronova UP
VLVG
< 20
GA content > 60%
Pronova UP
LVG
20 -200
GA content > 60%
Pronova UP
MVG
> 200
GA content > 60%
Pronova UP
VLVM
< 20
MA content > 50%
Pronova UP
LVM
20 -200
MA content > 50%
Pronova UP
MVM
> 200
MA content > 50%
Pronova UP (Sodium Alginate ) Test Kit containing approx. 2 gm of Pronova UP LVM, MVM, LVG and MVG grades available
PROTASAN UP
Ultra pure Chitosan salts
PROTASAN UP chitosans are ultra-purified and well-characterized water-soluble chitosan

chloride and glutamate salts and chitosan bases, for use in biomedical and pharmaceutical
applications such as wound healing, tissue engineering / repair, local delivery of cells, drugs,
proteins, genes, nasal drug delivery and non-viral gene delivery systems. PROTASAN UP
chitosans are manufactured in compliance with cGMP guidelines, ISO 9001:2000 and ISO
13485:2003 standards. Drug Master Files covering the chitosan salts and bases have also been
submitted to the US FDA.
Chitosan is a linear polysaccharide composed of randomly distributed b-(1,4)-linked Dglucosamine and N-acetyl-D-glucosamine It is produced commercially by deacetylation of
chitin, the structural element in the exoskeleton of crustaceans, with its viscosity primarily
dependent on the average molecular weight. Chitosan is positively charged, soluble in acidic to
neutral solutions, bioadhesive, biocompatible and biodegradable. It readily binds to negatively
charged surfaces such as mucosal membranes and enhances the transport of polar drugs across
epithelial surfaces.
Grade
Description
Viscosity (mPas)
Protasan UP B
80 20
Chitosan Base
20 - 199
Protasan UP B
80 200
Chitosan Base
200 - 499
Protasan UP B
80 500
Chitosan Base
500 - 999
Protasan UP B
90 20
Chitosan Base
20 - 199
Protasan UP B
90 500
Chitosan Base
500 - 999
Protasan UP B
90 1000
Chitosan Base
1000 - 2000
Protasan UP
CL 113
Chitosan Chloride EP
< 20
Protasan UP
CL 213
20 - 200
Protasan UP
CL 214
20 - 200
Protasan UP G
Chitosan Glutamate
< 20
113
Protasan UP G
213
Chitosan Glutamate
20 - 200
Protasan UP G
214
Chitosan Glutamate
20 - 200
Protasan UP Chitosan Test Kit Contains approx 2 gm of Protasan UP CL 113, CL 213, G 113 & G 213 grades also available
PVP-Iodine
Povidone - Iodine USP/NF, EP, JP
Iodine has been used for a long time in the form of tincture of iodine or Lugols solution for the
topical antiseptic treatment of minor wounds. Despite its high efficiency, limits were imposed on
a wider application, because these two formulations initiated a number of side-effects, i.e. gastric
irritation, allergy, etc.
In 1950s, Povidone-Iodine, a complex of Iodine with Povidone was first reported in literature &
forms the basis for the PVP Iodine range of topical antiseptics offered by BASF. PVP-Iodine
30/06 is the standard grade, preferred for preparations for application to the intact skin. PVPIodine 30/06 M 10 is a micronized grade, intended for use in suppositories and powder sprays.
Grade
Description
PVP-Iodine
30/06
Brown, pourable
powder soluble in
water, ethanol and
propanol.
PVP-Iodine
30/06 M10
Pale brown-orange,
micronized powder
soluble in water,
ethanol and propanol.
LYCOAT
Aqueous Film Coating System
Application
Used as a disinfectant in topical formulations such
as ointments, solutions, creams, suppositories,
sprays, etc. Also find use in gargles, mouth washes,,
surgical scrubs and soaps.
LYCOAT is a major breakthrough in aqueous film coating for immediate release, solid oral
dosage forms. It is modified peas starch presented as a stable, patent protected powder, instantly
dispersible in cold water at room temperature using traditional mixing equipment with no foam /
lump formation. LYCOAT suspensions are absolutely neutral and its coating does not impair
either the flavor or colour of the tablets. Coating time with LYCOAT is dramatically faster with
no production stops fro gun cleaning and even at high solids content, spraying is uniform. Tablets
coated with LYCOAT has a very attractive, glossy finish, smooth surface and uniform colour
tone. LYCOAT is available in two viscosities as well as in different colours to suit customer
needs.
Another interesting application where LYCOAT is used, is for the production of oro-dispersible
films.
Grade
Description
Application
Lycoat RS 780
Low viscosity grade
For immediate release, aqueous film coating of

tablets.
Lycoat RS 720
High viscosity grade
ReadiLYCOAT Ready-to-use film

coating system based
on LYCOAT
Used for aesthetic and functional benefits in tablets

with improved organoleptic properties, ease of
solubilization and process efficiency.
Lycoat NG 73
Used in the manufacture of orally disintegrating

films or mouth wafers.
Modified peas starch

film former
`GLUCOSE
Glucose or Dextrose is the monomer of natural starch polymer. It is white, odourless, sweet, in
crystalline or granular powder form and freely soluble in water. This monomer is also the natural
physiological sugar in the human body. In its crystalline form this doubly natural sugar has long
been used both as a filler for oral dosage forms and as a sweetener. It also helps in improving the
stability of API sensitive to oxidation due to its slight reducing properties. Therapeutically it is
Roquette has a range of dextrose products wide enough to meet any of manufacturers different
requirements.
Grade
Description
Application
Lycadex PF

monohydrate
Dextrose
Anhydrous PF

anhydrous
Dextrose GC
Agglomerated dextrose Direct compression diluent with excellent

monohydrate
compressibility and flowability for use in tablets,
sachets and capsule formulations.
Roferose
Dextrose Monohydrate Diluent for tablets, capsules and sachets.
Dextrose
Anhydrous C
anhydrous
Roclys
Dextrose syrup without For inhibiting sucrose crystallization as texturizer

and bulk sweetener in syrups, lozenges, pastilles and
Dextrose syrup with
Flolys

hypoglycemia.
GLUCOSE
Glucose or Dextrose is the monomer of natural starch polymer. It is white, odourless, sweet, in
crystalline or granular powder form and freely soluble in water. This monomer is also the natural
physiological sugar in the human body. In its crystalline form this doubly natural sugar has long
been used both as a filler for oral dosage forms and as a sweetener. It also helps in improving the
stability of API sensitive to oxidation due to its slight reducing properties. Therapeutically it is
Roquette has a range of dextrose products wide enough to meet any of manufacturers different
requirements.
Grade
Description
Application
Lycadex PF

monohydrate

hypoglycemia.
Dextrose
Anhydrous PF

anhydrous
Dextrose GC
Agglomerated dextrose Direct compression diluent with excellent
monohydrate
compressibility and flowability for use in tablets,

sachets and capsule formulations.
Roferose
Dextrose Monohydrate Diluent for tablets, capsules and sachets.
Dextrose
Anhydrous C
anhydrous
Roclys
Dextrose syrup without For inhibiting sucrose crystallization as texturizer

and bulk sweetener in syrups, lozenges, pastilles and
Dextrose syrup with
Flolys
SCORALITE
Calcium Carbonate USP/NF, EP, JP, BP
Scoralite is a very pure, highly free flowing synthetic calcium carbonate manufactured by using a
unique synthesis process. It possesses exceptional properties particularly valued in the
pharmaceutical industry. Production of Scoralite is carried out according to GMP guidelines and
is supplied under a C-O-S from the European Pharmacopeia.
Grade
Description
Application
Heavy grade
Inert filler and calcium source. Used in antacid

preparations, osteoporosis treatment tablets
alongwith Vitamin D3, mineral supplements, food
additives and in production of pharmaceutical grade
calcium derivatives.
Scoralite
Scoralite LL
Heavy grade with low

lead content
SICOVIT
Iron Oxide USP/NF, EP
The Sicovit product line comprises of insoluble iron oxide pigments powders of high purity for
use in the pharmaceutical and food industry. Sicovit Iron oxide colours are an useful tool to help
identify a product in its manufacturing and distribution stages. Patients often rely on color to be
able to recognize the prescribed medication. Also use of insoluble pigments like iron oxides,
titanium dioxide, etc in tablet coatings or gelatin shells provides good opacity and protection to
light sensitive actives.

The Sicovit product line is available in different colour shades to suit the end-user.
Grade
Description
Application
Sicovit Red
Red powder pigment
Stable colourant in pigment form, approved for use

in various dosage forms.
Sicovit Yellow
Yellow powder
pigment
Sicovit Black
Black powder pigment
Sicovit Brown
Brown powder pigment
SODIUM GLUCONATE PHARMA USP/NF
Sodium Gluconate Pharma is a pharmaceutical-grade of sodium gluconate with a low endotoxin

content. It is a pyrogen-free organic salts manufactured by natural starch through a fermentation
process.
Grade
Description
Application
Sodium
Gluconate
Pharma
White powder form,

low endotoxin content
Electrolyte for injectables and dialysis solutions, pH

regulation agent, emollient in cosmetics
Sodium Hyaluronate
Ultra pure Sodium Hyaluronate EP
Sodium Hyaluronate Pharma Grade consists of highly purified and well-characterized sodium
hyaluronate with controlled endotoxin content (Max 2.5 EU/g), )developed for use in biomedical
and pharmaceutical applications. Sodium Hyaluronate Pharma Grade is manufactured at a stateof-the-art ISO approved production facility in Japan by a fermentation process involving
Streptococcus zooepidemicus.
Sodium Hyaluronate is a linear copolymer composed of (-1,4)-linked D-glucuronate and (1,3)-N-acetyl-D-glucosamine. It is the only non-sulfated glycosaminoglycan and forms highly
viscous aqueous solutions as a direct result of trapping of approximately 1000 times its weight of
water by its expanded random coil structure. The ultra-pure sodium hyaluronates are clear
solutions and are described in a Drug Master File submitted to the US FDA. They forms an
attractive building block for new biocompatible and bio-interactive materials in drug delivery, in
tissue engineering and for visco-supplementation.
Grade
Intrinsic Viscosity (m3/kg)
Sodium Hyaluronate Pharma grade 80
1.2 2.0
2.1 2.8
2.9 3.5
SODIUM LACTATE PHARMA USP/NF, EP
Sodium Lactate Pharma is a highly purified single isomer and pyrogen free solution presented as
a clear, colourless, slightly syrupy liquid solution with neutral pH. It has low endotoxin content,
is heat stable and exhibits improved organoleptic properties. They are pyrogen-free organic salts
manufactured by natural starch through a fermentation process.
Grade
Description
Application
Sodium
Gluconate
Pharma 60%
Dry Sodium lactate

content (60%)
Electrolyte for injectables and dialysis solutions,

buffering agent in IV, pH regulation agent,
emollient, bacteriostatic agent.
Sodium
Gluconate
Pharma 50%
Dry Sodium lactate

content (50%)
SOLULYS
Corn-steep powder
Solulys is a spray- dried free flowing corn-steep powder produced by the industrial processing of
corn. It is rich in soluble proteins, vitamins and lactic acid making it useful as a culture medium
in the production of a variety of fermentation products- antibiotics, Vitamin B12, etc.
Grade
Description
Application
Spray dried corn-steep

powder
For seed culture as well as in main fermentation

process
Solulys AST
SOLUPHOR P
2-Pyrrolidone, Distilled
Soluphor P is available as a solidified excipient which is soluble in water and a number of

organic solvents, e.g. ethanol, isopropyl alcohol and aromatic hydrocarbons. The solutions of
Soluphor P in water of up to 50% have a viscosity of not more than 4 mPa.s, lending it useful in
injectable formulations.
Grade
Description
Application
Colourless or slightly
coloured liquid which
solidifies at room
temperature and has a
characteristic odour.
Used mainly as a solvent for veterinary injections.

Also indicated as absorption enhancer for topical
formulations using the transdermal or transmucosal
route.
Soluphor P
SOLUTOL HS 15
Macrogol-15-Hydroxystearate EP
Solutol HS 15 is a nonionic solubilizer and emulsifying agent obtained by reacting 15 moles of

ethylene oxide with 1 mole of 12-hydroxy stearic acid. It is soluble in water, ethanol and 2propanol to form clear solutions. Its solubility in water decreases with increasing temperature. It
is insoluble in liquid paraffin.
Solutol HS 15 has high chemical stability and is tolerated extremely well as several toxicological
tests have shown; especially a low histamine release after application of Solutol HS 15 is
observed.
Grade
Description
Application
Solutol HS 15
Yellowish white paste

Used as a non-ionic solubilizer in aqueous
at room temperature
parenteral preparations containing vitamins an
which transforms into a
liquid at approx.30C
STARCH USP/NF, EP, JP
Starch occurs as an odourless, tasteless, fine, white-to-off white coloured powder and has been
used for decades as one of the best known excipient in various pharmaceutical formulations.
Since the beginning of industrial pharmaceutical formulation, Starch has been used as a reliable
excipient in the form of fillers for tablets and capsules, as a powder for sachets and also as a
disintegrant.
Native Starches
Roquette supplies a variety of quality starches from different sources like maize (corn), wheat
and potato for pharmaceutical use. All the starch grades are GMO free and microbiologically
compliant.
Grade
Description
Application
Maize Starch 5
%
Low moisture grade
Used for moisture sensitive drug formulations.
Maize Starch B Standard grade

Extra White
Maize Starch
Extra-white grade
Corn Starch
400 L
Super-white grade,
highly refined.
Wheat Starch
TB
Standard grade
Potato Starch B Standard grade
Modified Starches
Pregelatinized Starch USP/NF, EP
Diluent for tablets and capsules, powder for sachets

and a disintegrant.
To overcome the drawbacks of native starch viz. cooking step, high viscosity, poor flow,
agglomeration etc; the modified range of starch products were introduced by Roquette. The
range consists of pre-cooked starches, partially-cooked starches, partially hydrolyzed starches as
well as compounded starches using special production processes. These modified starches
brought in a lot of reliability, flexibility and advantages for wet granulation as well as direct
compression tabletting.
Grade
Description
Application
Lycatab PGS
Fully
pregelatinize
d maize
starch
Excellent binder for wet granulation.
Lycatab C
Partially
pregelatinize
d maize
starch with
good flow
and
controlled
cohesive
power
Versatile excipient, filler-disintegrant

for hard gelatin capsules, binderdisintegrant for direct compression
and binder for wet granulation
applications. Also used as a flow-aid
in powder blends.
Lycatab D
Partially
hydrolyzed
maize starch
with good
flow, aqueous
solubility and
wettability
Cost effective binder for wet

granulation with high wettability.
Used to granulate mixtures for
capsule/sachet filling and densifying
mixtures for compression.
STARLAC
Spray-dried compound of Maize

Starch and Lactose Monohydrate
StarLac is an innovative, spray dried

compound of native maize starch and
alpha lactose monohydrate in a free
flowing powder form designed for
direct compression. It was developed
by Roquette in collaboration with
Meggle company as a part of its
ongoing drive towards innovation.
Starlac shows technical improvement
and added value for the tablet producer
as it easies tabletting process with an
outstanding combination of high
compactibility, superior flowability, fast

disintegration and excellent tablet
hardness.
Grade Benefits
Application
Starlac
Optimized
disintegration,
excellent
tablet
hardness,
superior
flowability,
high shear
force
resistancy,
higher storage
stability
Direct
compression
filler, lowdosage
formulations,
fast
dissolving
tablets,
capsule
filling, and
cores for
coating.
SH
Lycatab Mineral
Compound of Direct compressible filler / binder

Precipitated with an excellent mouth-feel. Also a
calcium
source of calcium.
carbonate and
maize starch
STEPANOL WA 100
Sodium Lauryl Sulfate USP/NF, EP, JP, BP
STEPANOL WA-100 is sodium lauryl sulfate which is a mixture of sodium alkyl sulfates mainly
consisting the lauryls. It is an anionic surfactant in white to off-white powder form with faint
characteristic odour of fatty substances.
Stepanol WA-100 is produced from the sulfation of fatty alcohol via Stepan's SO3 process. The
product is then spray dried to produce a highly active powder of exceptional quality for
pharmaceutical applications. It is characterized by a very high active substance matter and a very
low content of inorganic salts and unsulfated fatty alcohol.
Grade
Stepanol WA100
Description
Application
White spray-dried
powder with a smooth
feel and soapy, bitter
taste
Tablet and capsule lubricant, wetting agent, anionic

surfactant, emulsifying agent, skin penetrant and
skin cleanser in topical applications.
STURCAL L & CALOPAKE Extra Light
(Precipitated) Calcium Carbonate USP/NF, EP, JP

Precipitated Calcium Carbonate (PCC), alternatively known as purified, refined or synthetic
calcium carbonate is produced by direct carbonation of hydrated lime by a simple process called
Milk of lime process. The process involves combining lime (CaO) with water to form slaked
lime, addition of carbon dioxide and precipitation of calcium carbonate in a very fine, white
form. The precipitated calcium carbonate is then washed, purified, dried and packaged.
Specialty Minerals Inc. uses high quality limestone sources for its PCC products, including some
from the 150 year old SMI limestone mine in Adams, Massachusetts. Although a number of
different calcite crystal forms are possible, Sturcal L & Calopake Extra Light consist of
agglomerates of scalenohedral calcite crystals. The two grades differ in particle size and apparent
densities and are compliant as per USP/NF, EP & JP.
Grade
Sturcal L
Description
Heavy grade, apparent
density: 0.78 0.96
Calopake Extra Extra light grade, apparent

Light
density: 0.42 0.50
Median
Particl
e size
(m)
Application
75
Used mainly in antacid tablets and

liquids, in dentifrices &
therapeutically as calcium
supplement in pharmaceuticals &
fortified foods.
45
Used as abrasive in dentifrice

products, for calcium
supplementation in nutritional and
pharma products, also as antacid, pH
modulator and flocculent.
SUCROSE S-124
Ultra-Pure, Low-Endotoxin Sucrose USP/NF, EP, JP
Ferro Pfanstiehls ultra-pure, low-endotoxin sucrose grades are manufactured from highest purity
cane sugar or beet sugar. These base sugars are generally obtained from non-genetically modified
sources of sugar cane grass or sugar beet. Where commercial sources are not available, the
carbohydrates are either isolated from botanical sources or are manufactured via fermentation.
The ultra-pure, low-endotoxin sucrose grades are further purified through a combination of
various techniques including chromatography, deionization, ultrafiltration, nanofiltration,
activated carbon treatment and dissolution / re-crystallization under cGMP conditions. The end
product of high purity is thus suitable for the manufacture of regulated injectable formulation
grade ingredients or for use in injectable formulations.
Grade
Description
Sucrose S-124- White to-off-white

1
solid with endotoxin
content < 1,5 EU/g
Application
Used in parenteral drug formulations, particularly
intravenous and intramuscular injectables.
Sucrose S-124- White to-off-white

2-MC
powder with endotoxin
content < 0.6 EU/g
SYNPRO STEARATES
Stearates USP/NF, EP, JP
Synpro Stearates are special grade alkali stearates of vegetable origin refined for the
pharmaceutical industry. They are alkali salts (Magnesium, Zinc & Calcium) manufactured from
special grades of vegetable fatty acids with a particular emphasis put on sensory properties
ensuring absence of colour, odour, taste and favorable tactile qualities to get a superior endproduct.
Synpro Stearates are offered in a fine, consistent particle size, white powder form which ensures
consistent performance from batch to batch. They comply to all major international
pharmacopeias viz. USP/NF, EP and BP monographs and are well supported by all regulatory
documents like TSE/BSE, GMO, Residual solvents, Gluten free, Kosher etc. Synpro Stearates
are widely used as lubricants and mould release agents in the pharmaceutical and cosmetic
industry.
Grade
Application
Synpro Magnesium Stearate VG
Used as lubricant to improve granule flow during

tablet compression.
Synpro Zinc Stearate VG
Used as lubricant during tablet compression and as a

protective in formulations for treatment of skin
ailments.
Synpro Calcium Stearate VG
Used as lubricant to improve flow during tablet

compression and capsule filling.
TACKIDEX
Dextrin USP/NF, EP
Dextrins are starch polymers derived through solid-state heating from partially hydrolysed starch
of maize, tapioca or potato. It is partially or completely soluble in cold water with low viscosity.
Grade
Description
Tackidex B 167 White dextrin from

potato starch
Application
Tablet and capsule filler, binder for tablet
granulation, component in sugar coating solution,
thickening agent for suspensions.
TALC LUZENAC PHARMA
Talc USP/NF, EP, JP
Talc is a hydrated magnesium silicate and is the softest mineral in the world. It is a natural
material of white to grayish white colour and generally occurs in two morphologies, either in
macro or microcrystalline. Most talc deposits are mined, extracted, sorted depending on the talc
content and brightness and milled to obtain the right particle size. Talc is odorless, impalpable,
inert, water repellent, platy mineral and shows an affinity for organic substances.
Luzenac Talc products are purified, bacteria controlled grades and are manufactured according to
the IPEC GMP guide for bulk pharmaceutical excipients. They are heat-treated (sterilized) to
decontaminate them before being packaged. Additionally it is extra-white.
Grade
Description
Application
Talc Luzenac
Pharma
Standard grade
Flow regulator (glidant), reduces fluctuations in

tablet weight, enhances tablet homogeneity &
quality and increases productivity.
Talc Luzenac
Pharma M
Micronized grade
Anti-tack agent for tablet coating, eliminates

stickiness during drying, prevents agglomerations in
the coater, reduces coating time and produces
flawless coated products.
Talc Luzenac
Pharma UM
Ultra-micronized grade Lubricant for easier tablet pressing, reduces friction,

prevents binding during compression & ejection and
guarantees smooth crack-free results.
TREHALOSE
Non-reducing Di-Saccharide
Trehalose is a naturally occurring disaccharide present in plants like seaweeds, mushrooms,

yeast etc. It is odorless, moderately sweet and is supplied in form of either powder or crystalline
granules. It has distinctive characteristics like low reactivity to basic drugs, high stability to
moisture / heat & pH, high compactibility and faster disintegration than sugar alcohols. It is
digestible, has low laxative effect and is similar to sucrose in viscosity, osmotic pressure and
water reactivity.
Grade
Description
Application
Trehalose P
Powder
Filler & taste masking agent in solid & liquid

dosage forms.
Trehalose G
Granular
CALCIUM PHOSPHATES

Grade
Description
Application
A-Tab
Dibasic calcium
phosphate Anhydrous

Di-Tab
Dibasic calcium
phosphate Dihydrate

Tri-Tab
Tribasic calcium
Phosphate Anhydrous

Tri-Cal WG
Tribasic calcium
phosphate Anhydrous

CALCIUM PHOSPHATES
Grade
Description
Application
A-Tab
Dibasic calcium
phosphate Anhydrous

Di-Tab
Dibasic calcium
phosphate Dihydrate

Tri-Tab
Tribasic calcium
Phosphate Anhydrous

Tri-Cal WG
Tribasic calcium
phosphate Anhydrous

XANTURAL
Xanthan Gum USP/NF, EP, JP
Xantural is a exocellular polysaccharide produced by fermentation of a pure culture,

Xanthomonas campestris, with protein, carbohydrate source and other nutrients. Xantural gives
clear and transparent gel exhibiting pseudoplastic behaviour; the shear thinning being directly
proportional to the shear rate. The viscosity returns to normal immediately on release of shear
stress. It is nontoxic, compatible with most other pharmaceutical ingredients and has good
stability and viscosity properties over a wide pH and temperature range.
Xantural is widely used as a suspending and stabilizing agent, thickener and emulsifier.
Additionally, xanthan gums swell in gastric fluid to produce a highly viscous layer around the
tablet through which the drug must diffuse. This property makes Xantural a useful ingredient for
controlled and sustained release applications as well.
Grade
Description
Application
Xantural 75
Fine mesh grade with

particle size ~ 200
Reconstitutable oral suspensions & hydrophilic
mesh.
matrix / sustained release tablets.
Xantural 180
Coarse mesh grade

with particle size ~ 80
mesh.
Oral suspensions and syrups.
Xantural 11K
Agglomerated grade
with particle size ~ 14
mesh.
Oral suspensions and syrups. Disperses easily and

hydrates effectively.
XYLISORB
Xylitol USP/NF, EP, JP
Xylitol is a five-carbon polyol with a characteristic crystalline shape. It occurs as a white, sweet
tasting, odorless, granular solid comprising crystalline, equi-dimensional particles which are
stable to heat and marginally hygroscopic. Its sweetening power is identical to that of sucrose
and when combined with its distinct cooling effect in the mouth; it becomes highly effective in
enhancing the flavor of tablets and syrups and masking the unpleasant or bitter flavors associated
with some pharmaceutical actives.
Xylitol is used as a non-cariogenic sweetening agent and an alternative to sucrose in a variety of
pharmaceutical dosage forms, including tablets, syrups and coatings. It also finds increasing
application in chewing gum, mouth rinses and toothpastes as an agent that decreases dental
plaque and tooth decay (dental caries).
Grade
Description
Application
Xylisorb 90
Fine particle size
Diluent for sachets, chewable and suckable tablets.

Sugar free coating (non-cariogenic).
Xylisorb 300
Xylisorb 700
Xylisorb PF
Pyrogen free grade
Parenteral nutrition; used in combination with amino

acids.

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AC-DI-SOL

Croscarmellose Sodium USP/NF, EP, JP

Cross linked Sodium

Highly effective in wet granulation & direct

Agglomerated Sucrose USP/NF, EP, JP

SHIN-ETSU AQOAT (HPMCAS)

Hypromellose Acetate Succinate USP/NF, JPE

Micronized grades or aqueous

Granular grades for solventbased coating.

* In Mcllvaine's buffer (citric acidNa2HPO4) and USP Phosphate Buffer (NaOH

Cellulose Acetate Phthalate aqueous dispersion USP/NF, EP, JP

Aquacoat CPD- A water based pseudo30

Ethylcellulose aqueous dispersion USP/NF, EP, JP

A water based pseudolatex system

Sustained release beads for use in capsules / tablets,

masking of powders, granules, tablets and capsules.

Tablet and capsule diluent / filler, used in direct

Tablet and capsule diluent / filler, used in direct

Tablet and capsule diluent / filler, used in direct

high surface area and carrier of actives. Higher

Special high density grade for use in wet

Granular grades USP/NF, EP, JP

Tablet and capsule diluent / filler, used in direct

Tablet and capsule diluent / filler, used in

release agent and carrier of actives. Source

Tablet and capsule diluent / filler, used in

Special high density grade for use in wet

Free flowing powder,

Used for improved mouthfeel / superior sensory

Avicel DG is a synergistic combination of 75% of Microcrystalline Cellulose and 25% of

Dry granulation binder for roller compaction

AVICEL HFE - 102

Medium particle size

High functionality excipient for direct compression

of tablets, chewable tablets, fast dissolving tablets,

Fine particle size

For conventional applications, specially in

Medium particle size For improved flow in direct compression, dry

Low moisture with

Well suited for moisture sensitive actives.

Extra fine particle

For use in direct compression of coarse or

Very low moisture

Best for direct compression of moisture

Very low moisture

Improves product stability by extending the

Largest particle size

For best flow in direct compression and dry

Very low moisture

Best for direct compression of moisture

High bulk density

For manufacture of small tablets. reduces

High bulk density

For manufacture of thin tablets despite high

Bulk dried powder

Conventional suspending agent and dispersion aid.

Avicel RC-591 Spray dried powder

Used for oral suspensions, nasal sprays,

Avicel CL-611 Spray dried powder

Recommended for reconstitutable / dry

Blanose 7H4F- 2500 - 4500 (1%)

Tablet coatings - Film former