Subject: Electrical Engineer Job Position Application

My name is Chien-Chun Yang. I am writing to apply for an Electrical Engineer

position in your company.
With a M.S. degree from the University of Rochester and studying in both
Electrical Engineering and Biomedical Engineering as well as emphasizing in Medical
Imaging and Medical Image Analysis, I would like to interview for this Electrical
Engineer position. This opportunity allows me to apply and develop my theoretical
knowledge, research and working experiences in a practical setting, and I believe I
will be a strong asset to your team to solve variety of problems in a challenge and
fast pace environment.
Through my academic background and history, I have been focusing my
studies on DSP, Digital Logic Design, Electronic Circuit, Digital Image Processing,
Feature Extraction/Analysis, Pattern Recognition, Computer Vision and Machine
Learning.
I had experiences with DSP involving varieties of filter design and hardware
simulation with Texas Instrument DSP chip at bit-exact level. I also had one year
experience with FPGA involving Bandpass filter design with hardware co-simulation,
and advanced digital logic design using Verilog for embedded projects to interface
with digital ICs that include establishing protocol for RS-232, PS/2, VGA, DVI and
Ethernet. Besides, I have gained strong knowledge in electronic circuits through
hands-on projects and experiments such as ECG amplifier, Audiometer, circuits for
Biosignal/Vital Signs measurement. One project collaborated with my classmate,
Modular Design of Thermal Cautery Surgical Equipment, won the 1st prize of
Regional IEEE BME student paper contest in 2009.
Through my undergraduate studies, I have had knowledge and experiences
with DSP and electrical engineering design using MultiSim, Microcontroller and TI
DSP chip. In my previous work in Industrial Technology Research Institute, My
partner and I worked together to design and build a prototype working console
station for industrial automation machine, which uses motion control chips for multiaxes servo motors. We also designed Human Machine Interface using LabVIEW and
C/C++ in order to achieve real-time Automation Machine control and monitoring. At
the same time, I had experience with industrial communication protocols that
includes RS-232, RS-485 and EtherCAT.
In addition to the knowledge and experiences mentioned, I am also
specialized in Digital Image Processing, feature analysis, pattern recognition and
Machine Vision/Learning techniques in Medical Image application setting. Through
my studies and research in Rochester Center for Brain Imaging and Department of
Imaging Sciences in University of Rochester Medical Center, I have developed and
demonstrated knowledge of medical imaging modalities, feature analysis, pattern
recognition and machine learning techniques to support medical image research
and to improve the Computer-Aided Diagnosis system. I have had three years
practical experience in analyzing breast MRI, bone CT and breast cancer micro-CT
images with publications in conferences and journal. Besides the MRI and CT, I also
had hands-on projects experience with acoustic ultrasound and ultrasound images,

which are Using Microbubble-Aided Focus Ultrasound to Disrupt the Blood-Brain

Barrier in Assisting Drug Delivery for Alzheimer Treatment and Use Local
Frequency Estimation of Ultrasound Shear Wave to Detect Stiff Region (phantom).
In addition to the mentioned research experiences, while working in Professor
Axel Wismueller's Computational Radiology Lab, I gained tremendous knowledge,
developed strong research abilities and interpersonal communication as well as
teamwork skills with my professor and lab mates to solve real life clinical problems.
After graduating from the University of Rochester in 2013, I joined
Intersection Medical Inc. as an Electrical Engineer. My major duty is to assist senior
engineers and research scientists to research and develop medical device. My tasks
include but not limited to the following.
In hardware and electrical part, I assist hardware engineer to design and
verify analog filters (Passive, Active, LPF and HPF) and Multi-Stage/Multi-rate Digital
Filters (LPF, BPF, CIC, Half-Band, Moving Average and DC Removal Filters) for our
device. In the meantime, I am responsible for testing and verifying the designed
medical device, the associated electronic circuitry and GUI.
In software and algorithms development part, under minimal supervision
from research scientists, I am responsible for simulating and constructing
bioimpedance/bioelectrical resistivity mathematical model using WennerSchlumberger array techniques and perform biosignal analysis.
In addition, I worked closely with research scientists to develop algorithms to solve
challenge ill-posed inverse problems from measured biosignals in order to quantify
the resistivity inside human body. The process involves tremendous data mining
skills (both from biosignals and subjects pathology data), high dimensional feature
extraction/selection/analysis from raw human biosignal.
The skill sets, knowledge and techniques I use but not limit to are 3D
interpolation, regression, fix-effect and mix-effect mathematical modeling, k-means
clustering, SVD, PCA, Lasso and Elastic Net regularization, SVM, logistic regression,
linear & non-linear constrained optimization to solve ill-posed inverse problem. The
whole process of mathematical modeling, regression analysis, feature
extraction/analysis and machine learning all serve the same ultimate goal, which is
to analyze and process the acquired bioimpedance signals in order to assist
physicians clinical/diagnostic interpretation.
Besides the hardware testing, verification and algorithm development, I also
assist FDA specialist to setup the medical device testing protocols, Safety Protocol
Compliance (IEC 60601-1 and IEC-60601-2 for Medical Electrical Equipment
regulation), Quality Collaboration by Design (QCBD) to ensure the quality, safety
and the smoothness of the R&D phase.
To sum, my interdisciplinary academic background in both Electrical and
Biomedical Engineering provides me skill sets that include Verilog for Xilinx FPGA,
C/C++ programming, MATLAB, LabVIEW, and DSP algorithm development, which
makes me an exemplary candidate for this position.

With my academic background and past working experiences, I am confident

to work in this Electrical Engineer position, and willing to be part of the team to
solve challenge problems in real life.
My resume summarizes the experiences and projects that qualify me as an
exemplary candidate for this position, and I am able to start work in September. I
hope to hear from you soon regarding next steps in this process. Thank you very
much for your time and consideration.
P.S. Reference/Recommendation letters are available upon request.
Sincerely,
Chien-Chun Yang
University of Rochester M.S. Biomedical/Electrical Engineering
Email: chien.yang1984@gmail.com Phone: 562-338-6525