Bacillaceae
Bacillus anthracis
Corynebacteriacea
e
Corynebacterium
diphtheriae
Caracteristicas/DX
Spore forming, large
bacilli
Facultative or aerobic
Mostly saprophytic
Large grayish
colonies
Most are B-hemolytic
Etiologic agent of
anthrax
Straight rods with
square ends
(bamboo)
Non hemolytic
Non motile
Medusa-Head colony
Dx: Pear necklace,
fluorescence, PCR,
ELISA, gamma
bacteriophage test,
ascoli test for objects
Epidemiologia
Virulencia
Most are motile
Spores
Enf/Trat
Mainly a disease of
herbivores
Contact with dying
animals
Contact with animal
products (hides,hair
knitting yarn)
No data suggests
person-person
transmission
Plasmid coded
capsular polypeptide
of D-glutamic acid
Plasmid-coded
complex protein toxin
Cutaneous
Pulmonary
Intestinal anthrax
Woolsorters disease
Oropharyngeal
Variant
Malignant pustule
Trat:
Penicillin,
Ciprofloxacin, IV
doxycyxline
VACUNAS para
humanos y animales!
Pharyngeal difteria
-Bull neck ~ to
mumps
Cutaneous
Laryngeal
Nasal
Treatment: antitoxin
Erythromycin,
penicillin, tetracycline
VACUNA DPT, DPaT
Shick test determines
immu status
Notas
Aparte de
B.anthracis, ninguna
otra especie se
identifica, solo
genero.
Loeffler or tellurite
agar
ELISA PCR
Detection of
toxigenicity with gel
diffusion techniques
Listeria
monocytogenes
Facultative
Tumbling motility at
25C
Non motile 37C
Umbrella formation in
motility agar
Dx: cold enrichment
4C
B-hemolytic
CAMP +
Anton test (animal)
Large reservoir in
animals, flora of
adults and children
Erysipelothrix
rhusiopathiae
Single or long
filament
Small A-hemolytic
colonies
Erysipelas in animals
Erysipeloid in humans
Worldwide
distribution
Zoonotic,
occupational disease
(fishermen, butchers)
Intracell parasite
Listeriosin O (pore
forming cytolysin)
Agent of listeriosis
most lethal foodborne infection
Mild gastroenteritis
(pt may remain
carrier)
Meningitis, sepsis
Granulomatosis
infantiseptica
Treatment: ampicillin
and/or
aminoglycosides or
TMP-S, penicillin,
tetracycline
Violaceous, raised
lesion
Non suppurative,
itches, painful
Resolves in 3-4 wk
with antibiotic
treatment (Penicillin
G)
Rarely endocarditis,
death