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Xerosis
Ichthyosis, palmar hyperlinearity, or keratosis pilaris
Immediate (type 1) skin-test reactivity
Raised serum IgE
Early age of onset
Tendency toward cutaneous infections (especially S aureus and herpes
simplex) or impaired cell-mediated immunity
Tendency toward non-specific hand or foot dermatitis
Nipple eczema
Cheilitis
Recurrent conjunctivitis
Dennie-Morgan infraorbital fold
Keratoconus
Anterior subcapsular cataracts
Orbital darkening
Facial pallor or facial erythema
Pityriasis alba
Anterior neck folds
Itch when sweating
Intolerance to wool and lipid solvents
Perifollicular accentuation
Food intolerance
Course influenced by environmental or emotional factors
White dermographism or delayed blanch
Pruritus
Eczematous changes that are acute, subacute, or chronic:
a. Typical and age-specific patterns
(i) Facial, neck, and extensor involvement in infants and
children
(ii) Current or prior flexural lesions in adults/any age
(iii) Sparing of groin and axillary regions
b. Chronic or relapsing course
B. Important features that are seen in most cases, adding support to the
diagnosis:
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References:
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Rothe MJ, Grant-Kels JM. Diagnostic criteria for atopic dermatitis. Lancet.
1996; 348: 769-770. [Medline]
Rudikoff D, Lebwohl M. Atopic dermatitis. Lancet. 1998; 351: 1715-1721.
[Medline]
Simpson EL, Hanifin JM. Atopic dermatitis. Med Clin North Am. 2006
4.
Jan;90(1):149-67 [Medline]
Eichenfield LF, Tom WL, Chamlin SL, Feldman SR, Hanifin JM, Simpson EL,
Berger TG, Bergman JN, Cohen DE, Cooper KD, Cordoro KM, Davis DM, Krol
A, Margolis DJ, Paller AS, Schwarzenberger K, Silverman RA, Williams HC,
Elmets CA, Block J, Harrod CG, Smith Begolka W, Sidbury R. Guidelines of
care for the management of atopic dermatitis: section 1. Diagnosis and
assessment of atopic dermatitis. J Am Acad Dermatol. 2014 Feb;70(2):33851. [Medline]