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HypertonicSaline
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3%and5%SodiumChlorideInjection,USP
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3%and5%SodiumChlorideInjection,USPisasterile,nonpyrogenic,
hypertonicsolutionforfluidandelectrolytereplenishmentinsingledose
containersforintravenousadministration.ThepHmayhavebeenadjusted
withhydrochloricacid.Itcontainsnoantimicrobialagents.Composition,ionic
concentration,osmolarity,andpHareshowninTable1.
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SIZE COMPOSITION
(ML)
(G/L)
IONIC
CONCENTRATION
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(MEQ/L)
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CHLORIDE
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SODIUM CHLORIDE
USP(NACL)
3%
Sodium
Chloride
500
30
513
513
1027
Injection,
USP
PillIdentifieronRxList
quick,easy,
pillidentification
UsePillFinder
5%
Sodium
5.0
(4.5
to
7.0)
500
50
856
856
1711
Chloride
Injection,
USP
5.0
(4.5
to
7.0)
*Normalphysiologicalosmolarityrangeisapproximately280to310mOsmol/L.Administrationof
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including24hour,
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substantiallyhypertonicsolutions(600mOsmol/L)maycauseveindamage.
TheVIAFLEXplasticcontainerisfabricatedfromaspeciallyformulated
polyvinylchloride(PL146Plastic).Theamountofwaterthatcanpermeate
frominsidethecontainerintotheoverwrapisinsufficienttoaffectthe
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8/6/2015 HypertonicSaline(3%and5%SodiumChlorideInjection)DrugInformation:Description,UserReviews,DrugSideEffects,InteractionsPrescribingInfo
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solutionsignificantly.Solutionsincontactwiththeplasticcontainercanleach
outcertainofitschemicalcomponentsinverysmallamountswithinthe
expirationperiod,e.g.,di2ethylhexylphthalate(DEHP),upto5partsper
million.However,thesafetyoftheplastichasbeenconfirmedintestsin
animalsaccordingtoUSPbiologicaltestsforplasticcontainersaswellasby
tissueculturetoxicitystudies.
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LastreviewedonRxList:10/3/2008
Thismonographhasbeenmodifiedtoincludethegenericandbrandnameinmany
instances.
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