1.Introduction
biological activities. Compounds with cytostatic,
antiviral, antihelminthic, antifungal and antibacterial
activities have been detected in green, brown and red
algae (Newman et al., 2003; Chanda et al., 2010).
Seaweeds or marine algae are potentially prolific
source of highly bioactive secondary metabolites that
might represent useful leads in the development of
new pharmaceutical agents (Kolanjinathan et al.,
2014; Kolanjinathan and Saranraj, 2014). The present
study was undertaken to investigate the antibacterial
activities of solvent extract of seaweeds from
Mandapam coast against 11 human pathogenic
bacteria. The marine environments representing
approximately half of global biodiversity are an
enormous resource for new compounds.
146
Methanol
5
Staphylococcus aureus
170.5
Streptococcus pyogenes
170.3
Streptococcus epidermis
160.4
Proteus mirabilis
170.5
Bacillus cereus
160.4
Escherichia coli
170.5
Pseudomonas aeruginosa
170.3
Vibrio cholerae
150.3
Salmonella typhi
170.4
Klebsiella pneumonia
170.5
Serratia marcescens
170.6
- Standard deviation, *Ampicillin
10
210.3
220.4
200.6
210.5
200.2
200.3
200.5
170.4
200.6
210.5
210.3
Acetone
5
140.3
120.5
130.3
140.4
130.3
130.6
130.2
120.3
130.4
130.5
140.3
10
170.3
150.5
160.3
170.3
160.8
150.6
150.3
110.4
160.4
160.6
160.7
10
170.4
160.3
180.5
180.3
190.4
200.6
190.3
150.4
180.5
190.4
190.5
5
130.5
120.3
130.5
150.4
160.5
150.3
150.6
120.5
150.3
150.2
150.4
10
160.4
150.5
160.6
170.5
180.3
170.3
180.4
140.6
170.4
170.5
180.4
Ethanol
5
140.3
130.2
150.5
180.3
170.6
180.5
180.3
130.5
180.3
180.2
180.3
10
160.6
160.5
170.3
190.4
190.5
190.3
190.3
160.4
200.6
200.5
200.6
Positive
control*
10l
200.5
220.3
180.8
220.6
230.5
210.3
220.7
200.5
210.6
210.8
210.4
Chloroform
8
8
16
4
8
8
16
64
32
8
5
1
2
2
1
1
2
4
8
4
2
1
149
4
8
8
4
4
8
8
32
16
4
4
Ethanol
Positive Control*
2
4
4
2
2
4
8
16
8
2
2
4
8
8
8
8
4
4
16
16
8
8
Methanol
5
Staphylococcus aureus
150.5
Streptococcu spyogenes
150.3
Streptococcus epidermis
140.4
Proteus mirabilis
150.5
Bacillus cereus
140.4
Escherichia coli
160.5
Pseudomonas aeruginosa
160.3
Vibrio cholerae
130.3
Salmonella typhi
150.4
Klebsiella pneumonia
150.5
Serratia marcescens
150.6
- Standard deviation, *Ampicillin
Acetone
Ethanol
10
10
10
10
10
Positive
control*
10l
190.3
200.4
180.6
190.5
180.2
180.3
180.5
150.4
180.6
190.5
190.3
120.3
100.5
110.3
120.4
110.3
110.6
110.2
100.3
110.4
110.5
120.3
150.3
130.5
140.3
150.3
140.8
130.6
130.3
90.4
140.4
140.6
140.7
110.5
110.4
120.3
140.2
140.6
160.5
140.3
110.4
140.2
140.5
150.6
150.4
140.3
160.5
160.3
170.4
180.6
170.3
130.4
160.5
170.4
170.5
110.5
100.3
110.5
130.4
140.5
130.3
130.6
100.5
130.3
130.2
130.4
140.4
130.5
140.6
150.5
160.3
150.3
160.4
120.6
150.4
150.5
160.4
120.3
110.2
130.5
160.3
150.6
160.5
160.3
110.5
160.3
160.2
160.3
140.6
140.5
150.3
170.4
170.5
170.3
170.3
140.4
180.6
180.5
180.6
180.5
200.3
150.8
200.6
210.5
190.3
200.7
180.5
190.6
190.8
190.4
Chloroform
8
8
16
4
8
8
16
64
32
8
4
1
2
2
1
1
2
4
8
4
2
1
150
4
8
8
4
4
8
8
32
16
4
4
Ethanol
Positive Control*
2
4
4
2
2
4
8
16
8
2
2
4
8
8
8
8
4
4
16
16
8
8
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