MATERIALSAFETYDATASHEET

Titanium(IV)oxide
Section1ChemicalProductandCompanyIdentification
MSDSName:

Titanium(IV)oxide

Catalog
Numbers:

194340000,194340050,194340250,213580000,213580010,213580050,21358
1000,277370000,277370010,384290000,384290010,384290500,384292500

Synonyms:

Titaniumdioxide

CompanyIdentification:

AcrosOrganicsBVBA
JanssenPharmaceuticalaan3a
2440Geel,Belgium

CompanyIdentification:(USA)

AcrosOrganics
OneReagentLane
FairLawn,NJ07410

ForinformationintheUS,call:

800ACROS01

ForinformationinEurope,call:

+3214575211

EmergencyNumber,Europe:

+3214575299

EmergencyNumberUS:

2017967100

CHEMTRECPhoneNumber,US:

8004249300

CHEMTRECPhoneNumber,Europe:

7035273887

Section2Composition,InformationonIngredients
CAS#
13463677

ChemicalName:
Titanium(IV)oxide

%
>98%

EINECS#
2366755

HazardSymbols: XN

RiskPhrases:

40
Section3HazardsIdentification
EMERGENCYOVERVIEW
Limitedevidenceofacarcinogeniceffect.

PotentialHealthEffects
Eye:

Causesmildeyeirritation.

Skin:

Causesmildskinirritation.Maybeharmfulifabsorbedthroughtheskin.

Ingestion: Maycauseirritationofthedigestivetract.Maybeharmfulifswallowed.Ingestionoflarge
amountsmaycausepain,constipationordiarrhea.Maycauseataxia(failureofmuscular
coordination),increasedbloodpressure,hallucinations,hypermotility,muscle
contraction/spasticity,fatigue,psychosis,andtremors.
Inhalation: Maybeharmfulifinhaled.Maycausebloodchanges.Maycauseirritationoftheupper

respiratorytractandbronchi.
Chronic:

Prolongedorrepeatedexposuremaycauselungirritation,chestpain,andpulmonaryedema.
Limitedevidenceofacarcinogeniceffect.
Section4FirstAidMeasures

Eyes:

Flusheyeswithplentyofwaterforatleast15minutes,occasionallyliftingtheupper
andlowereyelids.Getmedicalaid.

Skin:

Getmedicalaid.Flushskinwithplentyofwaterforatleast15minuteswhileremoving
contaminatedclothingandshoes.

Ingestion:

Getmedicalaid.Washmouthoutwithwater.

Inhalation:

Removefromexposureandmovetofreshairimmediately.

Notesto
Physician:
Section5FireFightingMeasures
General
Information:

Asinanyfire,wearaselfcontainedbreathingapparatusinpressuredemand,
MSHA/NIOSH(approvedorequivalent),andfullprotectivegear.

Extinguishing
Media:

Substanceisnoncombustibleuseagentmostappropriatetoextinguishsurrounding
fire.
Section6AccidentalReleaseMeasures

GeneralInformation:

UseproperpersonalprotectiveequipmentasindicatedinSection8.

Spills/Leaks:

Vacuumorsweepupmaterialandplaceintoasuitabledisposalcontainer.
Section7HandlingandStorage

Handling:

Avoidcontactwitheyes,skin,andclothing.Avoidingestionandinhalation.

Storage:

Storeinacool,dryplace.Keepcontainerclosedwhennotinuse.
Section8ExposureControls,PersonalProtection

EngineeringControls:
Useadequateventilationtokeepairborneconcentrationslow.
Exposure
Limits
CAS#13463677:
UnitedKingdom,WELTWA:10mg/m3TWA(totalinhalable)4mg/m3TWA
(respirable)UnitedKingdom,WELSTEL:30mg/m3STEL(totalinhalable)12
mg/m3STEL(respirable)
UnitedStatesOSHA:15mg/m3TWA(totaldust)
BelgiumTWA:10mg/m3VLE
FranceVME:10mg/m3VME(asTi)
Malaysia:10mg/m3TWA
Netherlands:10mg/m3MAC
Russia:10mg/m3TWA(aerosol)
Spain:10mg/m3VLAED
PersonalProtectiveEquipment
Eyes:

Wearchemicalsplashgoggles.

Skin:

Wearappropriateprotectiveglovestopreventskinexposure.

Clothing:

Wearappropriateprotectiveclothingtopreventskinexposure.

Respirators: FollowtheOSHArespiratorregulationsfoundin29CFR1910.134orEuropeanStandardEN
149.UseaNIOSH/MSHAorEuropeanStandardEN149approvedrespiratorifexposure
limitsareexceededorifirritationorothersymptomsareexperienced.

Section9PhysicalandChemicalProperties
PhysicalState: Powder
Color: whitetooffwhite
Odor: odorless
pH: ~7
VaporPressure: Notavailable
Viscosity: Notavailable
BoilingPoint: 2900degC@760mmHg(5,252.00F)
Freezing/MeltingPoint: 1855degC(3,371.00F)
AutoignitionTemperature: Notavailable
FlashPoint: Notavailable
ExplosionLimits:Lower: Notavailable
ExplosionLimits:Upper: Notavailable
DecompositionTemperature: Notavailable
Solubilityinwater: Insoluble
SpecificGravity/Density: 4.230
MolecularFormula: O2Ti
MolecularWeight: 79.88
Section10StabilityandReactivity
ChemicalStability:

Stableundernormaltemperaturesandpressures.

ConditionstoAvoid:

Incompatiblematerials.

IncompatibilitieswithOther
Materials

Strongoxidizingagents,strongacids,alkalimetals,alkalineearth
metals,aluminum,zinc.

HazardousDecomposition
Products

Notavailable

HazardousPolymerization

Willnotoccur.
Section11ToxicologicalInformation

RTECS#:

CAS#13463677:XR2275000

LD50/LC50:

RTECS:Notavailable.Other:oralratLD50>10g/kgoralratLD50>12g/kgoralrat
LD50>20g/kgoralmouseLD50>10g/kginhratTCLo=250mg/m3/6H/2Yinhrat
LD>2.29mg/L/4HinhratLD>3.56mg/L/4HinhratLC>6.82mg/LskinrabbitLD>
10g/kgskinguineapigLD50>=10g/kgskinrabbit:notirritatingskinrabbit:slightly
irritatingskinhuman:lowirritancyeyerabbit:notirritatingeyerabbit:slightly
irritatingeyerabbit:mildirritationskinguineapig:notsensitizingskinhuman:not
sensitizing

Carcinogenicity: Titanium(IV)oxideIARC:Group3(notclassifiable)
Other:

Thetoxicologicalpropertieshavenotbeenfullyinvestigated.SeeactualentryinRTECS
forcompleteinformation.Mutagenicity:Amestest:negative.Possiblecarcinogen.
Section12EcologicalInformation

Ecotoxicity:

Fish:Leuciscusidus:>=1000mg/L48HLC0static
Daphnia:Daphnia:3mg/L30DEC0
Daphnia:Daphnia:1000mg/L18DEC100
Daphnia:Daphnia:500mg/L30DEC100
Section13DisposalConsiderations

Disposeofinamannerconsistentwithfederal,state,andlocalregulations.

Section14TransportInformation
IATA
Notregulated.

ShippingName:
HazardClass:
UNNumber:
PackingGroup:

IMO
Notregulated.

RID/ADR
Notregulated.

Section15RegulatoryInformation
European/InternationalRegulations
EuropeanLabelinginAccordancewithECDirectives
HazardSymbols:XN
RiskPhrases:
R40Limitedevidenceofacarcinogeniceffect.
SafetyPhrases:
S36/37Wearsuitableprotectiveclothingandgloves.
WGK(WaterDanger/Protection)
CAS#13463677:0
Canada
CAS#13463677islistedonCanada'sDSLList
USFederal
TSCA
CAS#13463677islistedontheTSCAInventory.
Section16OtherInformation
MSDSCreationDate: 7/16/1996
Revision#3Date 10/02/2006
RevisionsweremadeinSections: 2,3,9,11,14
Theinformationaboveisbelievedtobeaccurateandrepresentsthebestinformationcurrentlyavailableto
us.However,wemakenowarrantyofmerchantibilityoranyotherwarranty,expressorimplied,with
respecttosuchinformation,andweassumenoliabilityresultingfromitsuse.Usersshouldmaketheirown
investigationstodeterminethesuitabilityoftheinformationfortheirparticularpurposes.Innoeventshall
thecompanybeliableforanyclaims,losses,ordamagesofanythirdpartyorforlostprofitsorany
special,indirect,incidental,consequential,orexemplarydamageshowsoeverarising,evenifthecompany
hasbeenadvisedofthepossibilityofsuchdamages.