Schizophrenia Schematic Diagram

Prediscposing Factors:
*Genetics
*Neuro-Anatomy
*Neuro-Chemical
*Unknown

Neuro-Chemical:
*Increased
Dopamine
*Increased
Serotonin
*Excessive
neurotransmitters

Precipitating Factors:
*Environment
*Immuno-virologic

Neuro-Anatomy:
*Decreased brain
tissue and cerebospinal fluid
*Ventricle
enlargement
*Cortical atrophy
*Diminished glucose
metabolism at the
frontal area

*Viral Exposure
*Cytokine
inflammatory
mediator increase
*Cold
environments
*Triggers

Neuro-chemical
changes

Changes in neural activity:

Symptoms

Positive (Hard)
Symptoms:
*Associative Looseness
*Ambivalence
*Delusions
*Flight of Ideas
*Echopraxia
*Hallucinations
*Ideas of Reference
*Perseveration

Negative (Soft)
Symptoms
*Alogia
*Apathy
*Blunt Affect
*Catatonia
*Flat Affect
*Lack of Volition
*Anhedonia